Stereotactic radiosurgery for brain AVMs: Role of interobserver variation in target definition on digital subtraction angiography

Conclusion: Substantial interobserver variations exist when contouring brain AVMs on DSA for the purpose of radiosurgical planning. Such variations may result in underdosage to the AVM and, thereby, contribute to treatment failure. The consequences of contouring variations may increase with the use of more conformal radiosurgical techniques.