کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9872717 | 1533195 | 2005 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The dual parameter model containing pHi and T2 to predict the pCR in STSs treated with thermoradiotherapy was not verified. However, other parameters were statistically significant, including the PDE/Pi ratio and hypoxic fraction. These relationships may have interfered with our ability to obtain the pCR rate predicted by thermal doses achieved in these patients. The relationship between the PME/PDE ratio and metastasis-free and overall survival was provocative, but requires additional study to verify its predictive capability. Currently, 50% of all STS patients with high-grade tumors develop distant metastasis even when excellent local control is achieved. Parameters that could help select for patients who need adjuvant chemotherapy could have significant clinical benefit.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Radiation Oncology*Biology*Physics - Volume 61, Issue 2, 1 February 2005, Pages 480-491
Journal: International Journal of Radiation Oncology*Biology*Physics - Volume 61, Issue 2, 1 February 2005, Pages 480-491
نویسندگان
Mark W. D.V.M., Ph.D., Jean M. D.V.M., Ph.D., Daohai Ph.D., Linda M.S., Michaël D.V.M., Zeljko M.D., Ph.D., Ellen L. M.D., Thaddeus V. Ph.D., Barbara E. D.V.M., Ph.D., David M. M.D., Leonard R. M.D., H. Cecil Ph.D.,