کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9877524 1534078 2005 21 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A mechanism of synchronization in interacting multi-cell genetic systems
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
A mechanism of synchronization in interacting multi-cell genetic systems
چکیده انگلیسی
We investigate a general coupled noisy system with time delays, which may be applied to biologically plausible systems for cell-cell communication in a simplified context. The main conclusion is that appropriate noise intensities and coupling strengths are capable of driving the system to be synchronous. We first provide an analytical treatment for the synchronization process, based on the essential phase-locking mechanism, and then derive sufficient conditions which, if satisfied, ensure existence of the synchrony solution. Finally, a multi-cell system with a synthetic gene regulatory network, which contains both intracellular and extracellular noises and time delays, is adopted to demonstrate effects of extracellular noises and couplings on synchronization.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica D: Nonlinear Phenomena - Volume 211, Issues 1–2, 1 November 2005, Pages 107-127
نویسندگان
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