کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
989789 935458 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing the Determinants of the Potential for Cost-Effectiveness Over Time: The Empirical Case of COPD
ترجمه فارسی عنوان
ارزیابی عوامل تعیین کننده بالقوه برای اثربخشی هزینه در طول زمان: مورد تجربی COPD
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

ObjectivesThe objective of this study was to assess the potential for cost-effectiveness of new technologies for chronic obstructive pulmonary disease (COPD) over the period from 2001 to 2010.MethodsLung function outcomes and drug prices were observed for a UK COPD population over the period from 2001 to 2010. Cost-effectiveness was assessed at regular intervals on the basis of an established cost-effectiveness model, and the maximum price a technology providing cure could achieve under the current cost-effectiveness rules was estimated.ResultsThe results of this study show that although the scope for clinical improvement in COPD was still considerable, during the 10 years studied, the potential for cost-effectiveness at each point in time was dependent on momentary market characteristics, such as the changing price of comparators and improvements in clinical effectiveness. As a result, the analysis demonstrates that the future cost-effectiveness of a technology in development depends on the manner pricing and clinical effectiveness evolve throughout time.ConclusionsBecause any predictions will be short-lived and dependent on a number of uncertain factors, we conclude that producing accurate forecasts on the potential for cost-effectiveness of new therapies earlier during the development process is especially difficult under the current static cost-effectiveness framework.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Value in Health - Volume 16, Issue 2, March–April 2013, Pages 426–433
نویسندگان
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