کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9913313 1550308 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthetic bacterial lipopeptide analogs: structural requirements for adjuvanticity
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Synthetic bacterial lipopeptide analogs: structural requirements for adjuvanticity
چکیده انگلیسی
Synthetic analogs of bacterial lipoproteins were described more than a decade ago, but their capacity to act as adjuvants has been only recently dissected. These low molecular weight non-immunogenic molecules can be reproducibly synthetized, are safe, and of easy handling and administration. Furthermore, new experimental data from our laboratory reveal their powerful adjuvant effect on human HLA-I/II restricted T cell responses and identify the molecular and cellular requirements for optimal adjuvanticity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunobiology - Volume 210, Issues 2–4, 19 August 2005, Pages 211-215
نویسندگان
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