Time-Dependent Regional Myocardial Denervation as a Nonspecific Response to Transmyocardial Laser Revascularization

Transmyocardial revascularization caused partial alteration in myocardial innervation immediately after TMR. Tissue responses may continue to occur for the first 2 weeks after treatment. Tissue responses may also contribute to the development of denervation regardless of the energy source in non-ischemic canine myocardium.