Risk of Major Haemorrhage in Patients after Infrainguinal Venous Bypass Surgery: Therapeutic Consequences? The Dutch BOA (Bypass Oral Anticoagulants or Aspirin) Study

Treating patients at highest risk of major haemorrhage with aspirin instead of oral anticoagulants would have resulted in a reduction of non-fatal haemorrhages, but for venous bypasses this reduction was outweighed by an increase in ischemic events and graft occlusions. We still recommend treatment with oral anticoagulants after peripheral venous bypass surgery.