The Effect of Combined Angiotensin-Converting Enzyme Inhibition and Calcium Antagonism on Allograft Coronary Vasculopathy Validated by Intravascular Ultrasound

The combined use of an ACE inhibitor and a calcium antagonist is more effective than the individual use of either drug alone on the development of coronary vasculopathy in cardiac transplant recipients. Large randomized clinical trials are warranted to evaluate such a synergistic efficacy.