A Descriptive Study of Small Airway Reticular Basement Membrane Thickening in Clinically Stable Lung Transplant Recipients

Our data suggest that airway remodeling can occur early in lung allografts and before development of airflow limitation and BOS. Longitudinal pathophysiologic studies are needed to elucidate potential relationships between airway inflammation, Rbm thickening and allograft failure. Airway biopsies would be of value in such studies.