Recipient intramuscular cotransfection of transforming growth factor β1 and interleukin 10 ameliorates acute lung graft rejection

Recipient intramuscular cotransfection of transforming growth factor β1 and interleukin 10 suppressed interleukin 2 expression and provided a synergistic effect that reduced acute lung graft rejection. This approach might be applied to the clinical setting because transplant recipients could be treated at the time of implantation.