A Phe-rich region in short-wavelength sensitive opsins is responsible for their aggregation in the absence of 11-cis-retinal Fulltext Access 5 Pages 2013
Determination of topological structure of ARL6ip1 in cells: Identification of the essential binding region of ARL6ip1 for conophylline Fulltext Access 5 Pages 2013
NMR localization of the O-mycoloylation on PorH, a channel forming peptide from Corynebacterium glutamicum Fulltext Access 5 Pages 2013
Solution NMR determination of hydrogen bonding and base pairing between the glyQS T box riboswitch Specifier domain and the anticodon loop of tRNAGly Fulltext Access 5 Pages 2013
Michaelis and Menten and the long road to the discovery of cooperativity Fulltext Access 5 Pages 2013
Arabidopsis cysteine proteinase inhibitor AtCYSb interacts with a Ca2+-dependent nuclease, AtCaN2 Fulltext Access 5 Pages 2013
Structure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressive Brucella effector BtpA/Btp1/TcpB Fulltext Access 5 Pages 2013
Subcellular localization of the pyoverdine biogenesis machinery of Pseudomonas aeruginosa: A membrane-associated “siderosome” Fulltext Access 5 Pages 2013
Potassium ion-dependent trehalose phosphorylase from halophilic Bacillus selenitireducens MLS10 Fulltext Access 5 Pages 2013
Biochemical interactions between HIV-1 integrase and reverse transcriptase Fulltext Access 5 Pages 2013
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity Fulltext Access 5 Pages 2013
α-Galacturonidase(s): A new class of Family 4 glycoside hydrolases with strict specificity and a unique CHEV active site motif Fulltext Access 5 Pages 2013
Presynaptic kainate receptor-mediated facilitation of glutamate release involves Ca2+-calmodulin and PKA in cerebrocortical synaptosomes Fulltext Access 5 Pages 2013
The heme-copper oxidase superfamily shares a Zn2+-binding motif at the entrance to a proton pathway Fulltext Access 5 Pages 2013
A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway Fulltext Access 5 Pages 2013
HY5 regulates anthocyanin biosynthesis by inducing the transcriptional activation of the MYB75/PAP1 transcription factor in Arabidopsis Fulltext Access 5 Pages 2013
Irradiation-tolerant lung cancer cells acquire invasive ability dependent on dephosphorylation of the myosin regulatory light chain Fulltext Access 5 Pages 2013
An endogene-resembling transgene delays the onset of silencing and limits siRNA accumulation Fulltext Access 5 Pages 2013
Downregulation of miR-16 promotes growth and motility by targeting HDGF in non-small cell lung cancer cells Fulltext Access 5 Pages 2013
Escherichia coli multiple [Ni-Fe]-hydrogenases are sensitive to osmotic stress during glycerol fermentation but at different pHs Fulltext Access 5 Pages 2013
Structural differences between the closed and open states of channelrhodopsin-2 as observed by EPR spectroscopy Fulltext Access 5 Pages 2013
Aminoacylation of tRNA 2â²- or 3â²-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases Fulltext Access 5 Pages 2013
Effect of pH on the catalytic function and zinc content of native and immobilized anthrax lethal factor Fulltext Access 5 Pages 2013
The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site Fulltext Access 5 Pages 2013
The fission yeast Pvg1p has galactose-specific pyruvyltransferase activity Fulltext Access 5 Pages 2013
Ca2+-binding properties and regulatory roles of lobster troponin C sites II and IV Fulltext Access 5 Pages 2013
Contiguous RNA editing sites in the mitochondrial nad1 transcript of Arabidopsis thaliana are recognized by different proteins Fulltext Access 5 Pages 2013
The [NiFe]-hydrogenase accessory chaperones HypC and HybG of Escherichia coli are iron- and carbon dioxide-binding proteins Fulltext Access 5 Pages 2013
Effect of cargo size and shape on the transport efficiency of the bacterial Tat translocase Fulltext Access 5 Pages 2013
Recombinant expression of soluble murine prion protein for C-terminal modification Fulltext Access 6 Pages 2013
Stat3 inhibits WTX expression through up-regulation of microRNA-370 in Wilms tumor Fulltext Access 6 Pages 2013
A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae Fulltext Access 6 Pages 2013
Caveolin-1 up-regulates integrin α2,6-sialylation to promote integrin α5β1-dependent hepatocarcinoma cell adhesion Fulltext Access 6 Pages 2013
Completion of cell division is associated with maximum telomerase activity in naturally synchronized cultures of the green alga Desmodesmus quadricauda Fulltext Access 6 Pages 2013
The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner Fulltext Access 6 Pages 2013
Globular adiponectin modulates expression of programmed cell death 4 and miR-21 in RAW 264.7 macrophages through the MAPK/NF-κB pathway Fulltext Access 6 Pages 2013
Negative control of cell size in the cyanobacterium Synechococcus elongatus PCC 7942 by the essential response regulator RpaB Fulltext Access 6 Pages 2013
Synthesis of novel inhibitors blocking Wnt signaling downstream of β-Catenin Fulltext Access 6 Pages 2013
Chemomechanical coupling mechanism of F1-ATPase: Catalysis and torque generation Fulltext Access 6 Pages 2013
Interactions between subunits a and b in the rotary ATP synthase as determined by cross-linking Fulltext Access 6 Pages 2013
Functional conservation between mammalian MGRN1 and plant LOG2 ubiquitin ligases Fulltext Access 6 Pages 2013
General interaction mode of CIDE:CIDE complex revealed by a mutation study of the Drep2 CIDE domain Fulltext Access 6 Pages 2013
Triose phosphate isomerase from the blood fluke Schistosoma mansoni: Biochemical characterisation of a potential drug and vaccine target Fulltext Access 6 Pages 2013
DHTKD1 is essential for mitochondrial biogenesis and function maintenance Fulltext Access 6 Pages 2013
Phylogenetic analysis and substrate specificity of GH2 β-mannosidases from Aspergillus species Fulltext Access 6 Pages 2013
Phospho-ÎNp63α regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation Fulltext Access 6 Pages 2013
Distinct tRNA modifications in the thermo-acidophilic archaeon, Thermoplasma acidophilum Fulltext Access 6 Pages 2013
ADAM 10 is over expressed in oral squamous cell carcinoma and contributes to invasive behaviour through a functional association with αvβ6 integrin Fulltext Access 6 Pages 2013
Role of phospholemman and the 70Â kDa inhibitor protein in regulating Na+/K+ ATPase activity in pulmonary artery smooth muscle cells under U46619 stimulation Fulltext Access 6 Pages 2013
In silico investigation of PHD-3 specific HIF1-α proline 567 hydroxylation: A new player in the VHL/HIF-1α interaction pathway? Fulltext Access 6 Pages 2013
MicroRNAs with analogous target complementarities perform with highly variable efficacies in Arabidopsis Fulltext Access 6 Pages 2013
Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111) Fulltext Access 6 Pages 2013
Activation of the yeast cell wall integrity MAPK pathway by zymolyase depends on protease and glucanase activities and requires the mucin-like protein Hkr1 but not Msb2 Fulltext Access 6 Pages 2013
Conformational change of a unique sequence in a fungal galectin from Agrocybe cylindracea controls glycan ligand-binding specificity Fulltext Access 6 Pages 2013
Excision of 8-oxoguanine from methylated CpG dinucleotides by human 8-oxoguanine DNA glycosylase Fulltext Access 6 Pages 2013
FixL-like sensor FlbS of Brucella abortus binds haem and is necessary for survival within eukaryotic cells Fulltext Access 6 Pages 2013
Strand-specific RNA sequencing uncovers chloroplast ribonuclease functions Fulltext Access 6 Pages 2013
Characterization of the supporting role of SecE in protein translocation Fulltext Access 6 Pages 2013
LMO4 modulates proliferation and differentiation of 3T3-L1 preadipocytes Fulltext Access 6 Pages 2013
Additivity-based design of the strongest possible turkey ovomucoid third domain inhibitors for porcine pancreatic elastase (PPE) and Streptomyces griseus protease B (SGPB) Fulltext Access 6 Pages 2013
The essential gene YMR134W from Saccharomyces cerevisiae is important for appropriate mitochondrial iron utilization and the ergosterol biosynthetic pathway Fulltext Access 6 Pages 2013
Remaining structures at the N- and C-terminal regions of alpha-synuclein accurately elucidated by amide-proton exchange NMR with fitting Fulltext Access 6 Pages 2013
Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy Fulltext Access 6 Pages 2013
Isobavachalcone and bavachinin from Psoraleae Fructus modulate Aβ42 aggregation process through different mechanisms in vitro Fulltext Access 6 Pages 2013
A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A Fulltext Access 6 Pages 2013
Structural peculiarities of the (MHF1-MHF2)4 octamer provide a long DNA binding patch to anchor the MHF-FANCM complex to chromatin: A solution SAXS study Fulltext Access 6 Pages 2013
TNFα-induced miR-130 resulted in adipocyte dysfunction during obesity-related inflammation Fulltext Access 6 Pages 2013
Site-directed mutagenesis of a fatty acid elongase ELO-like condensing enzyme Fulltext Access 6 Pages 2013
Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain Fulltext Access 6 Pages 2013
Polypyrimidine tract binding protein (PTB) associates with intronic and exonic domains to squelch nuclear export of unspliced RNA Fulltext Access 6 Pages 2013
Interleukin-32δ interacts with IL-32β and inhibits IL-32β-mediated IL-10 production Fulltext Access 6 Pages 2013
Dimeric peptides of the C-terminal region of CXCL14 function as CXCL12 inhibitors Fulltext Access 6 Pages 2013
Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells Fulltext Access 6 Pages 2013
DksA2, a zinc-independent structural analog of the transcription factor DksA Fulltext Access 6 Pages 2013
Identification of a novel 'aggregation-prone'/'amyloidogenic determinant' peptide in the sequence of the highly amyloidogenic human calcitonin Fulltext Access 6 Pages 2013
Engrailed homeobox transcription factors as potential markers and targets in cancer Fulltext Access 6 Pages 2013
Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes Fulltext Access 6 Pages 2013
Two leucines in the N-terminal MAPK-docking site of tomato SlMKK2 are critical for interaction with a downstream MAPK to elicit programmed cell death associated with plant immunity Fulltext Access 6 Pages 2013
Crystal structure at 1.5Â Ã resolution of the PsbV2 cytochrome from the cyanobacterium Thermosynechococcus elongatus Fulltext Access 6 Pages 2013
Endoplasmic Reticulum stress reduces COPII vesicle formation and modifies Sec23a cycling at ERESs Fulltext Access 6 Pages 2013
Pyrrolysyl-tRNA synthetase variants reveal ancestral aminoacylation function Fulltext Access 6 Pages 2013
Amino acid sequence determinants in self-assembly of insulin chiral amyloid superstructures: Role of C-terminus of B-chain in association of fibrils Fulltext Access 6 Pages 2013
Studies with the Plasmodium falciparum hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis Fulltext Access 6 Pages 2013
Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124 Fulltext Access 6 Pages 2013
RNA self-processing: Formation of cyclic species and concatemers from a small engineered RNA Fulltext Access 6 Pages 2013
Molecular basis of the NO trans influence in quaternary T-state human hemoglobin: A computational study Fulltext Access 6 Pages 2013
AtDGAT2 is a functional acyl-CoA:diacylglycerol acyltransferase and displays different acyl-CoA substrate preferences than AtDGAT1 Fulltext Access 6 Pages 2013
miR-150 promotes the proliferation of lung cancer cells by targeting P53 Fulltext Access 6 Pages 2013
Enzymatic characterization of an active NDH complex from Thermosynechococcus elongatus Fulltext Access 6 Pages 2013
Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes Fulltext Access 6 Pages 2013
Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL Fulltext Access 6 Pages 2013
pH-rate profiles support a general base mechanism for galactokinase (Lactococcus lactis) Fulltext Access 6 Pages 2013