The oxidative neurotoxicity of clioquinol
Keywords: β-آمیلوئید; Alzheimer's disease; β-Amyloid; Chelator; Iron; Free radical; Oxidative;
مقالات ISI β-آمیلوئید (ترجمه نشده)
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AP-1 mediates β-amyloid-induced iNOS expression in PC12 cells via the ERK2 and p38 MAPK signaling pathways
Keywords: β-آمیلوئید; AP-1; β-Amyloid; ERK; iNOS; Nitrosative stress; p38 MAPK; PC12 cells;
The expression of calcium/calmodulin-dependent protein kinase II-α in the hippocampus of patients with Alzheimer's disease and its links with AD-related pathology
Keywords: β-آمیلوئید; Degenerative disease; Alzheimer's miscellaneous; Alzheimer's disease; Hippocampus; Calcium/calmodulin-dependent protein kinase II-α; Hyperphosphorylated tau; β-Amyloid; Senile plaques;
Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42
Keywords: β-آمیلوئید; AD; Alzheimer's disease; Aβ; β-amyloid; ThT; Thioflavin T; AFM; atomic force microscopy; MTT; 3-2,5-diphenyltetrazolium bromide; Alzheimer's disease; Beta-amyloid; Trehalose; Aggregation; Atomic force microscope; Cytotoxicity; Oligomers;
Can tau filaments be both physiologically beneficial and toxic?
Keywords: β-آمیلوئید; Tau filament; β-Amyloid; Alzheimer's disease;
Sequence variants of IDE are associated with the extent of β-amyloid deposition in the Alzheimer's disease brain
Keywords: β-آمیلوئید; IDE; Linkage disequilibrium; Alzheimer's disease; β-Amyloid;
The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of β-amyloid
Keywords: β-آمیلوئید; Aβ; β-amyloid; AD; Alzheimer's disease; APP; β-amyloid precursor protein; DD; death domain; JICD; juxtamembrane domain; p75NTR; p75 neurotrophin receptor; PI3K; phosphatidylinositide 3-kinase; AO; acridine orange; EB; ethidium bromide; WT; wortmannin;
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to β-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
Keywords: β-آمیلوئید; Microglia; β-amyloid; Alzheimer's disease; Transgenic; Bone marrow; Transplantation; Recruitment; Inflammation;
The synthetic estrogen 4-estren-3α,17β-diol (estren) induces estrogen-like neuroprotection
Keywords: β-آمیلوئید; 4-Estren-3α, 17β-Diol; Estren; Estrogen; 17β-Estradiol; 17α-Estradiol; β-Amyloid; Neuroprotection; Protein kinase C; Alzheimer's disease;
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice
Keywords: β-آمیلوئید; APP; β-amyloid; Tau; Lysosomes; Stereology; Neuronal loss; Transgenic mice; Alzheimer's disease;
Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease
Keywords: β-آمیلوئید; Methionine; Methionine sulfoxide; Sulfide radical cation; One-electron oxidation; Hydroxyl radical; β-Amyloid; Alzheimer's disease; Aging;
Age-dependent differential expression of BACE splice variants in brain regions of tg2576 mice
Keywords: β-آمیلوئید; β-Secretase; Alternative splice variants; Brain regions; Age dependent; APP; β-Amyloid; tg2576 transgenic mice; Alzheimer disease;
Novel d-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases
Keywords: β-آمیلوئید; Wilson's disease; Alzheimer's disease; Metal chelation; β-Amyloid; Copper; Aggregates; Resolubilization;
Endogenous β-amyloid peptide synthesis modulates cAMP response element-regulated gene expression in PC12 cells
Keywords: β-آمیلوئید; intracellular Aβ; β-amyloid; CRE-regulated gene expression; ERK; Alzheimer's disease; synaptic plasticity; Aβ; β-amyloid; AD; Alzheimer's disease; AICD; AβPP intracellular C-terminal domain fragment; AβPP; β-amyloid precursor protein; CBP; cAMP
Red cell interactions with amyloid-β1-40 fibrils in a murine model
Keywords: β-آمیلوئید; Erythrocytes; β-Amyloid; Alzheimer's disease; Murine in vivo study; Spleen; Liver; Immunohistochemistry;
Chronic treatment with amyloid β1-42 inhibits non-cholinergic high-affinity choline transport in NG108-15 cells through protein kinase C signaling
Keywords: β-آمیلوئید; Disorders of the nervous system; Degenerative disease: Alzheimer's beta amyloid; Amyloid β-peptide1-42; Aβ1-42; Amyloid Precursor Protein; APP; Hemicholinum-3; HC-3; Choline Transporter-like Protein 1; CTL1; High-affinity choline transporter 1; ChT1
β-Amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-κB signaling pathway
Keywords: β-آمیلوئید; β-Amyloid; ERK; COX-2; Inflammatory cell death; NF-κB; p38 MAPK; PC12 cells; Oxidative stress;
Reductions in β-amyloid concentrations in vivo by the γ-secretase inhibitors BMS-289948 and BMS-299897
Keywords: β-آمیلوئید; Aβ; β-amyloid; APP; Amyloid precursor protein; DAPT; [N-(3,5-difluor-phenacetyl)-l-alanyl]-S-phenylglycine; BMS-289948; 4-chloro-N-(2,5-difluorophenyl)-N-((1R)-{4-fluoro-2-[3-(1H-imidazol-1-yl)propyl]phenyl}ethyl)benzenesulfonamide hydrochloride; BMS-29
Effect of d-amino acids at Asp23 and Ser26 residues on the conformational preference of Aβ20-29 peptides
Keywords: β-آمیلوئید; β-Amyloid; β-sheet; β-turn; α-helix; Peptide; Aggregation; Circular dichroism; d-Amino acid; Racemization;
Expression and purification of a recombinant peptide from the Alzheimer's β-amyloid protein for solid-state NMR
Keywords: β-آمیلوئید; Alzheimer's; β-Amyloid; Amyloid fibrils; Solid-state NMR;
Stress in the brain: novel cellular mechanisms of injury linked to Alzheimer's disease
Keywords: β-آمیلوئید; Disorders of the nervous system; Degenerative disease: Alzheimer's-miscellaneous; β-Amyloid; Akt; Cysteine proteases; Erythropoietin; Metabotropic; Wnt;
The role of α-synuclein in neurodegenerative diseases
Keywords: β-آمیلوئید; αSp22; O-glycosylated α-synuclein; 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid; AD; Alzheimer's disease; A; adenine; Ala; alanine; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; AR-JP; autosomal recessive juvenile parkinsonism; BS3;
Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease
Keywords: β-آمیلوئید; Aβ; β-amyloid; AD; Alzheimer's disease; AIF; apoptosis-inducing factor; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; APC; adenomatous polyposis coli; APP; amyloid precursor protein; BrdU; bromodeoxyuridine; CARD; cas