Cardenolides from Calotropis gigantea as potent inhibitors of hypoxia-inducible factor-1 transcriptional activity
Keywords: (HIF-) 1; hypoxia-inducible factor; (SAR); structure-activity relationship; (IC50); concentrations that reduced HIF-1 transcriptional activity or cell viability of MCF-7 or MCF-10A by 50%; Cardenolide; Calotropis gigantea; HIF-1 inhibitor; cytotoxicity; A