Keywords: 15-لیپوکسیژناز; RA; rheumatoid arthritis; RF; rheumatoid factor; ACPA; anti-citrullinated protein antibodies; AA; arachidonic acid; PG; prostaglandins; LT; leukotrienes; TX; thromboxanes; LX; lipoxins; NSAID; non steroidal anti-inflammatory drugs; COXIB; COX-2 selective
مقالات ISI 15-لیپوکسیژناز (ترجمه نشده)
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Keywords: 15-لیپوکسیژناز; Aronia melanocarpa; A. prunifolia; DPPH; 15-Lipoxygenase; Xanthine oxidase; α-Glucosidase;
Keywords: 15-لیپوکسیژناز; Pulmonary arterial hypertension; Placenta growth factor; 15-Hydroxyeicosatetraenoic acid; 15-Lipoxygenase; Pulmonary artery endothelial cell;
15-Lipoxygenase/15-hydroxyeicosanoid and activator protein 1 contribute to hypoxia-induced pulmonary artery smooth muscle cells phenotype alteration
Keywords: 15-لیپوکسیژناز; Hypoxia; Activator protein 1; Proliferation; Pulmonary artery smooth muscle cells; 15-hydroxyeicosanoids; AA; arachidonic acid; AP-1; Activator protein 1; PA; pulmonary artery; PAH; pulmonary arterial hypertension; PASMC; pulmonary arterial smooth muscle
Role of extracellular vesicles in rheumatoid arthritis
Keywords: 15-لیپوکسیژناز; FLS; fibroblast-like synoviocyte; APC; antigen presenting cell; EV; extracellular vesicle; MMP; matrix metalloproteinase; VEGF; vascular endothelial growth factor; Id1; inhibitor of DNA binding 1; CD13; aminopeptidase N; MCP; monocyte chemoattractant prot
The potential use of leaf extracts of two Newtonia (Fabaceae) species to treat diarrhoea
Keywords: 15-لیپوکسیژناز; AchEI; acetylcholinesterase inhibitors; MIC; minimum inhibitory concentration; DPPH; 2,2â²-diphenyl-1-picrylhydrazyl; ABTS; 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions
Keywords: 15-لیپوکسیژناز; 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-
Development of a novel monoclonal antibody against 4-hydroxy-2E,6Z-dodecadienal (4-HDDE)-protein adducts: Immunochemical application in quantitative and qualitative analyses of lipid peroxidation in vitro and ex vivo
Keywords: 15-لیپوکسیژناز; Fe3+-NTA; Ferric nitrate enneahydrate and nitrilotriacetic acid disodium salt; 5-HpETE; 5-Hydroperoxyeicosatetraenoic acid; 12-HpETE; 12-Hydroperoxyeicosatetraenoic acid; 15-HpETE; 15-Hydroperoxyeicosatetraenoic acid; 4-HDDE; 4-Hydroxy-2E,6Z-dodecadienal;
ReviewMildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles
Keywords: 15-لیپوکسیژناز; 15-LO; 15-lipoxygenase; ABCA1; ATP-binding casette transporter A1; apo; apolipoprotein; apoA-I; apolipoprotein A-I; apoB; apolipoprotein B; AUC; area under the curve; AU; aggregation units; BCA; bicinchoninic acid assay; BMP; bis(monoacylglycero)phosphate
Substituted (E)-2-(2-benzylidenehydrazinyl)-4-methylthiazole-5-carboxylates as dual inhibitors of 15-lipoxygenase & carbonic anhydrase II: synthesis, biochemical evaluation and docking studies
Keywords: 15-لیپوکسیژناز; Thiazoles; 15-Lipoxygenase; Bovine carbonic anhydrase II; Docking studies;
Antioxidants and HNE in redox homeostasis
Keywords: 15-لیپوکسیژناز; 15-LOX; 15-lipoxygenase; 4-HNE; 4-hydroxynonenal; AKRs; aldo-keto reductases; ALDHs; aldehyde dehydrogenases; AP-1; activator protein 1; ARE; antioxidant responsive element; Bcl-2; B-cell lymphoma 2; COX-2; cyclooxygenase-2; DHN; 1,4-dihydroxy-2-nonene;
Resolvin D1 via prevention of ROS-mediated SHP2 inactivation protects endothelial adherens junction integrity and barrier function
Keywords: 15-لیپوکسیژناز; AJ; adherens junctions; CD; chow diet; CSN; cysteine sulfonate; DHA; docosahexanoic acid; EV; Evans blue; Frk; Fyn-related kinase; GJ; gap junctions; HUVEC; human umbilical vein endothelial cells; 15-LOX; 15-lipoxygenase; LSGS; low-serum growth supplement
(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid: A stable isomer of 15(S)-HETE that retains key vasoconstrictive and antiproliferative activity
Keywords: 15-لیپوکسیژناز; Arachidonic acid; 15-Lipoxygenase; 15-HETE; Vasoconstriction; Proliferation
Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; Thiophene-based inhibitor; Substitution Oriented Screening; Multi component chemistry; Inflammation; NeurodegenerationDMF, dimethylformamide; EtOAc, ethyl acetate; EtOH, ethanol; Et2O, diethyl ether; TEA, trimethylamine; rt, room temperat
Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers
Keywords: 15-لیپوکسیژناز; Syzygium guineense; Ethnopharmacology; Antioxidants; DPPH; Xanthine oxidase; 15-lipoxygenase;
Synthesis and structure-activity relationship study of tacrine-based pyrano[2,3-c]pyrazoles targeting AChE/BuChE and 15-LOX
Keywords: 15-لیپوکسیژناز; Acetylcholinesterase; Butyrylcholinesterase; 15-Lipoxygenase; Alzheimer's disease; Tacrine;
Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; Nitric oxide; Natural compounds; RAW264.7 macrophages;
3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; Inhibitors; Arachidonic acid; Pyrazole; Triazole; Benzoxazole
N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; Inhibitors; Arachidonic acid; Pyrazole
On the biosynthesis of 15-HETE and eoxin C4 by human airway epithelial cells
Keywords: 15-لیپوکسیژناز; Asthma; Airway epithelial cells; 15-Lipoxygenase; 15-HETE; Eoxin C4; Glutathione transferase; Pseudomonas aeruginosa;
15–Lipoxygenase inhibition of Commelina benghalensis, Tradescantia fluminensis, Tradescantia zebrina
Keywords: 15-لیپوکسیژناز; Inflammation; Medicinal plants; Plant extracts; 15-Lipoxygenase
Synthesis, biological evaluation and docking study of 3-aroyl-1-(4-sulfamoylphenyl)thiourea derivatives as 15-lipoxygenase inhibitors
Keywords: 15-لیپوکسیژناز; Thiourea; Sulfonamides; Enzyme inhibitors; 15-Lipoxygenase; Antioxidant activity; Docking study
Enzyme inhibition, antioxidant and immunomodulatory activities, and brine shrimp toxicity of extracts from the root bark, stem bark and leaves of Terminalia macroptera
Keywords: 15-لیپوکسیژناز; Terminalia macroptera; α-Glucosidase; 15-Lipoxygenase; Xanthine oxidase; DPPH; Immunomodulation;
Imidazo[2,1-b]thiazole derivatives as new inhibitors of 15-lipoxygenase
Keywords: 15-لیپوکسیژناز; Imidazo[2,1-b]thiazole; Enzyme inhibitors; 15-Lipoxygenase; Docking study;
Immunopharmocology and inflammationEnhancement of PLGF production by 15-(S)-HETE via PI3K-Akt, NF-κB and COX-2 pathways in rheumatoid arthritis synovial fibroblast
Keywords: 15-لیپوکسیژناز; COX-2; 15-lipoxygenase; Inflammation; PLGF; Synovial fibroblasts;
Eicosanoid biosynthesis during mucociliary and mucous metaplastic differentiation of bronchial epithelial cells
Keywords: 15-لیپوکسیژناز; Airway epithelium; Eicosanoids; Goblet cell metaplasia; Th2 cytokines; 15-Lipoxygenase;
Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype
Keywords: 15-لیپوکسیژناز; Resolution of inflammation; Macrophages; Galectin-1; 15-Lipoxygenase; Efferocytosis;
Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins
Keywords: 15-لیپوکسیژناز; Endothelial cells; High density lipoprotein; 15-Lipoxygenase; LOX-1
Biosynthesis of eoxin C4 by porcine leukocytes
Keywords: 15-لیپوکسیژناز; Porcine eosinophil; Arachidonic acid; 12/15-Lipoxygenase; 15-Lipoxygenase; Eoxin; 15-Hydroxyeicosatetraenoic acid
Bioactive polyphenols in Ximenia americana and the traditional use among Malian healers
Keywords: 15-لیپوکسیژناز; Ximenia americana; Ethnopharmacology; Polyphenols; DPPH; Xanthine oxidase; 15-Lipoxygenase;
Preeclampsia activates 15-lipoxygenase and its metabolite 15-hydroxyeicosatetraenoic acid enhances constriction in umbilical arteries
Keywords: 15-لیپوکسیژناز; 15-lipoxygenase; 15-hydroxyeicosatetraenoic acid; Umbilical artery; Vasoconstriction; Preeclampsia
Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta
Keywords: 15-لیپوکسیژناز; AA; arachidonic acid; 15-LO-1; 15-lipoxygenase-1; THETA; 11,12,15-trihydroxyeicosatrienoic acid; HEETA; 15-hydroxy-11,12-epoxyeicosatrienoic acid; NO; nitric oxide; ACH; acetylcholine; LNA; nitro-l-arginine; LO; lipoxygenase; GC; guanylate cyclase; NDGA;
NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells
Keywords: 15-لیپوکسیژناز; 15-LOX; 15-lipoxygenase; AD; Alzheimer's disease; CFH; complement factor H; HNG; human neuronal-glial; LPS; lipopolysaccharide; miRNA; micro RNA; PDTC; pyrollidine dithiocarbamate; SYN-2; (SYN-II, synapsin-2); TNFα; tumor necrosis factor alpha; TSPAN-12;
Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; Inhibitors; Pyrazole; Sulfonamides; Sulfamides; Arachidonic acid; Linoleic acid
Identification of the methylation preference region in heterogeneous nuclear ribonucleoprotein K by protein arginine methyltransferase 1 and its implication in regulating nuclear/cytoplasmic distribution
Keywords: 15-لیپوکسیژناز; hnRNP K; heterogeneous nuclear ribonucleoprotein K; PRMT1; protein arginine methyltransferase 1; RGG box; glycine- and arginine-rich box; DICE; differentiation control element; LOX; 15-lipoxygenase; MAPKs; mitogen-activated protein kinases; Erk; extracell
Î9-Tetrahydrocannabinol and Its Major Metabolite Î9-Tetrahydrocannabinol-11-oic Acid as 15-Lipoxygenase Inhibitors
Keywords: 15-لیپوکسیژناز; 15-lipoxygenase; atherosclerosis; Î9-Tetrahydrocannabinol; metabolism. oxidation; inhibition; Î9-THC-11-oic acid; lipid/lipoprotein; low-density lipoprotein; structure-activity relationship;
Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells
Keywords: 15-لیپوکسیژناز; LOX-1; LDL; 15-Lipoxygenase; Endothelial cells; ICAM-1;
γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer
Keywords: 15-لیپوکسیژناز; GT3; R-γ-tocotrienol; 15-LOX-2; 15-lipoxygenase-2; 15-S-HETE; 15-S-hydroxyeicosatetraenoic acid; NF-κB; nuclear factor κB; TGFβ; transforming growth factor β; TAK-1; TGFβ-activating kinase-1; TAB-1; TGFβ-activating kinase-1 subunit; AT; RRR-α-toco
Functional and pathological roles of the 12- and 15-lipoxygenases
Keywords: 15-لیپوکسیژناز; AD; Alzheimer's disease; AIF; apoptosis-inducing factor; AA; arachidonic acid; CAM; cellular adhesion molecule; CDC; cinnamyl-3,4-dihydroxy-α-cyanocinnamate; COX; cyclooxygenase; EPA; eicosapentaenoic acid; ESI; electrospray ionization; ELISA; enzyme-l
Resolution, the grail for healthy ocular inflammation
Keywords: 15-لیپوکسیژناز; neutrophil; macrophage; acute inflammation; resolution; heme-oxygenase; 15-lipoxygenase; retina; cornea; ω-3 PUFA; neuroprotectionPUFA, polyunsaturated fatty acid; DHA, Docosahexaenoic Acid, ω-3 PUFA C22:6; AA, eicosatetraenoic acid, ω-6 PUFA C20:4; ALX,
Cloning, purification and characterization of non-human primate 12/15-lipoxygenases
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; 12-Lipoxygenase; Phylogeny; Arachidonic acid; Anandamide; Endocannabinoid; Inflammation
No association of two functional polymorphisms in human ALOX15 with myocardial infarction
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; 12-Lipoxygenase; 15-LOX; 12-LOX; ALOX15; ALOX12; Inflammation; Atherosclerosis; Myocardial infarction; Genetics; Haplotype; Polymorphism;
Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation
Keywords: 15-لیپوکسیژناز; BSTFA, N,O-Bis(trimethylsilyl)-trifluroroacetamide; HFBI, heptafluorobutyryl imidazole; DHA, docosahexaenoic acid; sLOX, soybean lipoxygenaseDocosahexaenoic acid; 15-Lipoxygenase; 10,17-Dihydroxy-docosahexaenoic acid; Double lipoxygenation; Ion mobility s
Computational analysis of R and S isoforms of 12-Lipoxygenases: Homology modeling and docking studies
Keywords: 15-لیپوکسیژناز; Lipoxygenase; 12R-LOX; 12S-LOX; 15-Lipoxygenase; Homology modeling; Molecular docking
Subacute hypoxia suppresses Kv3.4 channel expression and whole-cell K+ currents through endogenous 15-hydroxyeicosatetraenoic acid in pulmonary arterial smooth muscle cells
Keywords: 15-لیپوکسیژناز; Kv3.4; 15-lipoxygenase; 15-hydroxyeicosatetraenoic acid; Subacute hypoxia; Pulmonary arterial smooth muscle cells
Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues
Keywords: 15-لیپوکسیژناز; Asthma; microarrays expression profiling; candidate genes; genetic association study; tagging single nucleotide polymorphism; 15-lipoxygenase; AHR; Airway hyperresponsiveness; ALOX15; Arachidonate 15-lipoxygenase gene; CAPPS; Canadian Asthma Primary Preve
Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs
Keywords: 15-لیپوکسیژناز; Nordihydroguaiaretic acid; NDGA; Insulin-like growth factor 1 receptor; IGF-1R; 15-Lipoxygenase; 15-LOX
Discovery of selective imidazole-based inhibitors of mammalian 15-lipoxygenase: Highly potent against human enzyme within a cellular environment
Keywords: 15-لیپوکسیژناز; 15-Lipoxygenase; Inhibition; Imidazole; Sulfonamide; Sulfamide; Arachidonic acid; Linoleic acid
Design and synthesis of pyrimido[4,5-b][1,4]benzothiazine derivatives, as potent 15-lipoxygenase inhibitors
Keywords: 15-لیپوکسیژناز; Pyrimido[4,5-b][1,4]benzothiazine; 5-Bromo-2,4-dichloro-6-methylpyrimidine; 15-Lipoxygenase; Docking; Molecular modeling; QSAR
Activation of cytosolic phospholipase A2 and 15-lipoxygenase by oxidized low-density lipoproteins in cultured human lung fibroblasts
Keywords: 15-لیپوکسیژناز; Phospholipase A2; 15-lipoxygenase; Low-density lipoprotein; MAP kinases; Fibroblasts;