دانلود مقالات ISI درباره 3-Bromopyruvate + ترجمه فارسی

Menadione-mediated WST1 reduction assay for the determination of metabolic activity of cultured neural cells

Keywords: Brain; Cell viability; Electron cycler; Menadione; Metabolic activity; WST1; 3-BP; 3-bromopyruvate; ANOVA; analysis of variance; DMEM; Dulbecco's modified Eagle's medium; GFAP; glial fibrillary acidic protein; FCS; fetal calf serum; LDH; lactate dehydroge

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

3-Bromopyruvate treatment induces alterations of metabolic and stress-related pathways in glioblastoma cells

Keywords: Glioblastoma; GL15 cells; 3-Bromopyruvate; Proteomics; Two-dimensional gel electrophoresis; Mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

مهار گلیکولیز و اثر آن در مقاومت به دوکسوروبیسین در نوروبلاستوما

Glycolysis inhibition and its effect in doxorubicin resistance in neuroblastoma

Keywords: Glycolysis inhibition; Neuroblastoma; ATP; 3-bromopyruvate; Doxorubicin;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

نقش مولکولی آنزیم های گلیکولیتی در مرگ سلولی

Modulatory roles of glycolytic enzymes in cell death

Keywords: Glycolysis; Cancer; Cell death; GAPDH; Hexokinase; ANT; adenine nucleotide translocase; APAF-1; apoptotic protease activating factor-1; ATG5; autophagy related 5; ATP; adenosine triphosphate; Bak; Bcl-2 homologous antagonistic killer; Bax; Bcl-2-associate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

3-Bromopyruvate reverses hypoxia-induced pulmonary arterial hypertension through inhibiting glycolysis: In vitro and in vivo studies

Keywords: Pulmonary arterial hypertension; 3-Bromopyruvate; Glycolysis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Antitumor action of 3-bromopyruvate implicates reorganized tumor growth regulatory components of tumor milieu, cell cycle arrest and induction of mitochondria-dependent tumor cell death

Keywords: 3-Bromopyruvate; Tumor metabolism; Tumor progression; Tumor milieu;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Valproate sensitizes human glioblastoma cells to 3-bromopyruvate-induced cytotoxicity

Keywords: Glioblastoma; 3-Bromopyruvate; Valproate; ATP-binding cassette transporter; Monocarboxylate transporter;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

The promising anticancer drug 3-bromopyruvate is metabolized through glutathione conjugation which affects chemoresistance and clinical practice: An evidence-based view

Keywords: Glutathione; 3-Bromopyruvate; Conjugation; Cancer; Metabolism; Paracetamol;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation

Keywords: 3-BrPA; 3-bromopyruvate; ΔΨm; mitochondrial membrane potential; DMS; dimethyl succinate; HDAC; histone deacetylase; ETC; electron transport chain; HIF-1; hypoxia-inducible factor 1; IGF-1R; insulin-like growth factor 1 receptor; IDH; isocitrate dehydrog

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleA perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells

Keywords: Bromopyruvate; Monocarboxylate transporter; Perillyl alcohol; Protein alkylation; 3-BP; 3-bromopyruvate; CFA; colony formation assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSH; glutathione; MCT-1; monocarboxylate transporter 1; NAC; N-acetylcys

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Antitumor and chemosensitizing action of 3-bromopyruvate: Implication of deregulated metabolism

Keywords: 3-Bromopyruvate; Thymoma; Dalton's lymphoma; Metabolism; Cell survival; Apoptosis; Necrosis;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Anticancer agent 3-bromopyruvic acid forms a conjugate with glutathione

Keywords: 3-Bromopyruvate; Erythrocyte; Glutathione; Mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

ABCB1-overexpressing MDCK-II cells are hypersensitive to 3-bromopyruvic acid

Keywords: MDKC-II cells; ABCB1 protein; ABCG2 protein; Multidrug resistance; 3-Bromopyruvate; ATP; 3-BP; 3-bromopyruvic acid; FDG; [18F]fluorodeoxyglucose; Pgp; P-glycoprotein (ABCB1 protein);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming

Keywords: SHMT; serine hydroxymethyltransferase; SHMT1; cytosolic SHMT; SHMT2; mitochondrial SHMT; 3BP; 3-bromopyruvate; PLP; pyridoxal 5′-phosphate; H4PteGlu; tetrahydropteroylglutamate; Cancer metabolic reprogramming; Serine hydroxymethyltransferase; Isozymes;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondria: 3-bromopyruvate vs. mitochondria? A small molecule that attacks tumors by targeting their bioenergetic diversity

Keywords: 3-Bromopyruvate; Glycolytic inhibitor; Mitochondrial respiration inhibitor; Alkylation; Tumor cell metabolism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

p53 inactivation decreases dependence on estrogen/ERK signalling for proliferation but promotes EMT and susceptility to 3-bromopyruvate in ERα+ breast cancer MCF-7 cells

Keywords: Epithelial-mesenchymal transition; Estrogen hypersensitivity; MEK inhibition; 3-Bromopyruvate; mutant p53 R175H; mutant p53 Arg 175His; wt; wild type; ERα; estrogen receptor alpha; 3-BrPA; 3-bromopyruvate; E2; estradiol; EMT; epithelial-mesenchymal t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin

Keywords: Multi-walled carbon nanotubes; Platinum(IV) prodrug; Cisplatin; Mitochondria; Rhodamine; 3-Bromopyruvate;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

PARP and other prospective targets for poisoning cancer cell metabolism

Keywords: ATP; adenosine 5′-triphosphate; 3-BrPA; 3-bromopyruvate; EGFR; epidermal growth factor receptor; FDA; food and drug administration; GSH; glutathione; GSSG; oxidized GSH; GST; glutathione S-transferase; HDAC; histone deacetylase; HIF1; hypoxia inducible

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2014 سفارش ترجمه

3-Bromopyruvate: A novel antifungal agent against the human pathogen Cryptococcus neoformans

Keywords: 3-Bromopyruvate; Antifungal activity; Cryptococcus neoformans;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Oroxylin A sensitizes non-small cell lung cancer cells to anoikis via glucose-deprivation-like mechanisms: c-Src and hexokinase II

Keywords: polyHEMA; poly-2-hydroxyethylmethacrylate; 3-BrPA; 3-bromopyruvate; PP2; 4-amino-3-(4-chlorophenyl)-1-(t-butyl)-1H-pyrazolo[3,4-d]pyrimidine; NAC; Nacetylcysteine; MTT; 3-[4,5-dimethylthiazol-2-yl] 2,5-diphenyltetrazolium bromide; DAPI; 4′, 6-diamidino-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Antiglycolytic Therapy Combined with an Image-guided Minimally Invasive Delivery Strategy for the Treatment of Breast Cancer

Keywords: ATP; adenosine triphosphate; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; H&E; hematoxylin and eosin; MEM; modified Eagle medium; MMP; matrix metalloproteinase; PBS; phosphate-buffered saline; PCR; polymerase chain reaction; 3-BrPA; 3-bromopyruvate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines

Keywords: ATP; 3-Bromopyruvate; Glutathione; Melanoma; Metabolomics; Superoxide anion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies

Keywords: Cancer; Mitochondria; Warburg effect; Hexokinase 2; VDAC; 3-bromopyruvate;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleMalignant but not naïve hepatocytes of human and rodent origin are killed by TNF after metabolic depletion of ATP by fructose

Keywords: HKII; hexokinase II; HIF1; hypoxia-inducible factor1; TNF; tumor necrosis factor-alpha; IHP; isolated hepatic perfusion; EC; effective concentration; Br-PA; 3-bromopyruvate; Selective targeting; Hepatocellular carcinoma; TNF; Hexokinase II; Warburg theory

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy

Keywords: Warburg; Cancer; Hexokinase-2; PET analysis; 3-Bromopyruvate; Cancer therapy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate

Keywords: Warburg effect; Mitochondria; Hexokinase II; 3-Bromopyruvate; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Intraarterial Therapy with a New Potent Inhibitor of Tumor Metabolism (3-bromopyruvate): Identification of Therapeutic Dose and Method of Injection in an Animal Model of Liver Cancer

Keywords: ATP; adenosine triphosphate; CI; confidence interval; HCC; hepatocellular carcinoma; 3-BrPA; 3-bromopyruvate; TUNEL; doxynucleotidyl transferase-mediated dUTP nick end labeling;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Local Toxicity of Hepatic Arterial Infusion of Hexokinase II Inhibitor, 3-Bromopyruvate: In Vivo Investigation in Normal Rabbit Model

Keywords: 3-Bromopyruvate; hexokinase II inhibitor; intra-arterial chemotherapy; hepatotoxicity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Inactivation of H+-vacuolar ATPase by the energy blocker 3-bromopyruvate, a new antitumour agent

Keywords: 3-bromopyruvate; Ehrlich ascites tumour cells; Acidic compartments; Lysosomes; H+-vacuolar ATPase; Antitumour drugs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه