Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis
Keywords: Multiple sclerosis; Biotin; Promyelinogenic agent; Virtual hypoxia; ACC; acetyl-CoA carboxylase; AMN; adrenomyeloneuropathy; BBB; blood-brain barrier; BTBGD; biotin-thiamine responsive basal ganglia disease; EDSS; Expanded Disability Status Scale; HLCS;