Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; 8-OHdG, 8-hydroxy-2-deoxyguanosine; ALT, alanine aminotransferase; AST, aspartate transaminase; BUN, blood urea nitrogen; Cr, Creatinine; ELISA, enzyme-linked immuno sorbent assay; I/R injury, ischemia–reperfusion injury; MCAO, midd
مقالات ISI 3-NT، 3-نیتروتیروسین (ترجمه نشده)
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Blood–brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation
Keywords: 3-NT، 3-نیتروتیروسین; NOS, Nitric oxide synthase; NO, Nitric oxide; ONOO−, Peroxynitrite; 3-NT, 3-nitrotyrosine; BBB, Blood–brain barrier; ZO-1, Zonula occludens-1; MMP, Matrix metalloproteinase; TJ, Tight junction; Hb, Hemoglobin; nNOS, Neuronal NOS; iNOS, Inducible NOS; eNOS
Chronic administration of methylmalonate on young rats alters neuroinflammatory markers and spatial memory
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; BBB, blood–brain barrier; BCIP/NBT, 5-bromo-4-chloro-3-indolyl phosphate and p-nitro blue tetrazolium; BSA, bovine serum albumin; CNS, central nervous system; COX-2, cyclooxygenase-2; ELISA, enzyme-linked immunosorbent assay; EPM, e
Exhaled breath condensate: Determination of non-volatile compounds and their potential for clinical diagnosis and monitoring. A review
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; 5-HPETE, 5-hydroperoxyeicosatetraenoic acid; 5-LO, 5-lipoxygenase; 8-IP, 8-isoprostane; ALF, airway lining fluid; BAL, bronchoalveolar lavage; CF, cystic fibrosis; COPD, chronic obstructive pulmonary disease; COX, cyclooxygenase; EB
Protective effects of (−)-epicatechin against nitrative modifications of fibrinogen
Keywords: 3-NT، 3-نیتروتیروسین; PN, Peroxynitrite; Fg, Fibrinogen; DMSO, Dimethylsulfoxide; C-ELISA, Competition ELISA; 3-NT, 3-nitrotyrosine; Vmax, Maximum velocity; HMW, High molecular weight proteinsFibrinogen; Peroxynitrite; (−)-Epicatechin; Flavonoids; Antioxidative; 3-nitrotyrosin
Competitive, non-competitive, and mixed format cleavable tag immunoassays
Keywords: 3-NT، 3-نیتروتیروسین; CTI, cleavable tag immunoassay; MCE, microchip capillary electrophoresis; 3-NT, 3-nitrotyrosine; T4, thyroxine; CRP, C-reactive protein; RNS, reactive nitrogen species; ELISA, enzyme linked immunosorbent assays; CEIA, capillary electrophoresis immunoassay
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; AD, Alzheimer disease; HNE, 4-hydroxy-2-nonenal; HO, heme oxygenase; MCI, mild cognitive impairment; PC, protein carbonyls; pSer, phosphoserine; pThr, phosphothreonine; pTyr, phosphotyrosineAlzheimer disease; Heme oxygenase; Mild co
Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; 8-OHdG, 8-hydroxy-2-deoxyguanosine; BAL, bronchoalveolar lavage; CuZnSOD, copper–zinc superoxide dismutase; ECSOD, extracellular superoxide dismutase; GPx-1, glutathione peroxidase 1; HO-1, heme oxygenase-1; iNOS, inducible nitric o
The inflammatory footprints of alcohol-induced oxidative damage in neurovascular components
Keywords: 3-NT، 3-نیتروتیروسین; Blood–brain barrier; Microvessels; Oxidative damage; Tight junction; NeuroinflammationAch, acetaldehyde; BBB, blood–brain barrier; EtOH, ethanol; 3-NT, 3-nitrotyrosine; NOX1, NADPH oxidase 1; 4HNE, 4-hydroxynononal; iNOS, inducible nitric oxide synthase;
Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: A novel mechanism of action
Keywords: 3-NT، 3-نیتروتیروسین; PC, protein carbonyls; HNE, 4-hydroxy-2-nonenal; 3-NT, 3-nitrotyrosine; Aβ, amyloid beta peptide; 7-K, 7-ketocholesterol; 25-OH, 25-hydroxy cholesterolAlzheimer disease; Atorvastatin; Cholesterol oxidation products; Oxidative stress; Cognitive function
Intravenous low redox potential saline attenuates FeCl3-induced vascular dysfunction via downregulation of endothelial H2O2, CX3CL1, intercellular adhesion molecule-1, and p53 expression
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; 4-HNE, 4-hydroxynonenal; DCFDA, 2’,7’-dichlorodihydrofluorescein diacetate; DPI, diphenylene iodonium; HUVEC, human umbilical vein endothelial cell; ICAM-1, intercellular adhesion molecule-1; OCT, optimal cutting temperature; ORP, o
Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: Role of asymmetric dimethylarginine
Keywords: 3-NT، 3-نیتروتیروسین; ALI, acute lung injury; LPS, lipopolysaccharide; ADMA, asymmetric dimethylarginine; DDAH, dimethylarginine dimethylaminohydrolase; 3-NT, 3-nitrotyrosine; NO, nitric oxide; NOS, nitric oxide synthaseNitration; Superoxide; Arginine metabolism
Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice
Keywords: 3-NT، 3-نیتروتیروسین; AMPK, AMP-activated protein kinase; AOX, acyl-CoA oxidase; CYP2E1, cytochrome P4502E1; DHE, dihydroethidine; 4-HNE, 4-hydroxynonenal; GSH, reduced glutathione; IG, intragastric; KO, knockout; KI, knock-in; 3-NT, 3-nitrotyrosine; PPARα, peroxisome prolifer
Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
Keywords: 3-NT، 3-نیتروتیروسین; TNF, tumor necrosis factor; CYP2E1, cytochrome P4502E1; PY, pyrazole; 1400W, N-(3-aminomethyl)benzylacetamindine; NAC, N-acetyl-l-cysteine; MAPK, mitogen-activated protein kinase; 3-NT, 3-nitrotyrosine; ALT, alanine aminotransferase; AST, aspartate aminot
Renin-angiotensin-aldosterone system-mediated redox effects in chronic kidney disease
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; 8-OHdG, 8-hydroxy-deoxyguanosine; ACE, angiotensin converting enzyme; Ang II, angiotensin II; ARB, angiotensin receptor blocker; Aogen, angiotensinogen; AT1R, angiotensin type 1 receptor; BP, blood pressure; CCD, cortical collecting
Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease
Keywords: 3-NT، 3-نیتروتیروسین; AD, Alzheimer's disease; HNE, 4-hydroxy-2-nonenal; IPL, inferior parietal lobule; MCI, mild cognitive impairment; NO, nitric oxide; 3-NT, 3-Nitrotyrosine; PCO, protein carbonyls; SOD, superoxide dismutaseMild cognitive impairment (MCI); Alzheimer's diseas
Interaction between COX-2 and iNOS aggravates vascular lesion and antagonistic effect of ginsenoside
Keywords: 3-NT، 3-نیتروتیروسین; COX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; ONOO−, peroxynitrite; 3-NT, 3-nitrotyrosine; Tm, melting temperature; LCSM, laser confocal scanning microscopy; TEM, transmission electron microscope; PGs, prostaglandins; eNOS, endothelial N
Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency
Keywords: 3-NT، 3-نیتروتیروسین; CYP, Cytochrome P450; GST, glutathione-S-transferase; 3-NT, 3-nitrotyrosine; LPS, lipopolyssachride; Vc, vitamin C; Nrf2, nuclear factor erythroid 2-related factor 2; iNOS, inducible nitric oxide synthase; GCS, γ-glutamylcysteine synthetase; SAM, S-adenos
Protein tyrosine nitration—Functional alteration or just a biomarker?
Keywords: 3-NT، 3-نیتروتیروسین; ARDS, acute respiratory distress syndrome; BTBE, N-t-BOC L-tyrosine tert butyl ester; PGH synthase, prostaglandin endoperoxide H synthase; GR, glutathione reductase; 3-NT, 3-nitrotyrosine; SOD, superoxide dismutase; TH, tyrosine hydroxylase3-nitrotyrosine
Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: Therapeutic implications for Parkinson's disease explained via in silico studies
Keywords: 3-NT، 3-نیتروتیروسین; PD, Parkinson's disease; SN, Substantia nigra; PN, Peroxynitrite; CI, Mitochondrial complex I; DTNB, 5,5-dithio-bis-2-nitrobenzoic acid; DTT, Dithiothreitol; 3-NT, 3-nitrotyrosine; ROS, Reactive oxygen species; RNS, Reactive nitrogen species; GSH, Glutath
In vitro activity of the essential oils of Origanum vulgare, Satureja montana and their main constituents in peroxynitrite-induced oxidative processes
Keywords: 3-NT، 3-نیتروتیروسین; EO, essential oil; 3-NT, 3-nitrotyrosine; MDA, malondialdehydePeroxynitrite; Malondialdehyde; 3-Nitrotyrosine; Origanum vulgare; Satureja montana; Essential oils; Carvacrol; Thymol
Low nitric oxide: a key factor underlying copper-deficiency teratogenicity
Keywords: 3-NT، 3-نیتروتیروسین; NOS, nitric oxide synthase; iNOS, inducible nitric oxide synthase; eNOS, endothelial nitric oxide synthase; Cu+, copper adequate; Cu−, copper deficient; SOD, superoxide dismutase; O2−, superoxide anion; ONOO−, peroxynitrite; 3-NT, 3-nitrotyrosine; cGMP, c
Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
Keywords: 3-NT، 3-نیتروتیروسین; 3-NT, 3-nitrotyrosine; 8-OHdG, 8-hydroxy-2-deoxyguanine; 8-OHG, 8-hydroxyguanine; Aβ, amyloid β-peptide; AD, Alzheimer disease; APP, amyloid precursor protein; CAII, carbonic anhydrase II; CK BB, creatine kinase BB isoform; CSF, cerebrospinal fluid; DHAP,
In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: Relevance to Alzheimer’s disease and other oxidativ
Keywords: 3-NT، 3-نیتروتیروسین; Aβ(1–42), amyloid β-peptide 1–42; AD, Alzheimer’s disease; D609, tricyclodecan-9-yl-xanthogenate; DAG, diacylglycerol; GPx, glutathione peroxidase; GR, glutathione reductase; GST, glutathione S-transferase; HNE, hydroxynonenal; 3-NT, 3-nitrotyrosine; PBS,