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Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction
Keywords: 4-MU، 4-methylumbelliferone; UGT, UDP-glucuronosyltransferase; HLMs, human liver microsomes; QSAR, quantitative structure activity relationship; HDI, herb-drug interactions; CYPs, cytochrome P450s; TCAs, tricyclic antidepressants; 4-MU, 4-methylumbelliferone; MgCl, 22magnesium chlori