Keywords: 5-Aza-2'-deoxycytidine; Epigenetics; Prostate cancer; ERβ1; HDAC inhibition;5-aza-2â²-deoxycytidine; DPN;
مقالات ISI 5-Aza-2'-deoxycytidine (ترجمه نشده)
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Keywords: 5-Aza-2'-deoxycytidine; Airway inflammation; asthma; phthalates; epigenetics; TÂ cells; AHR; Airway hyperreactivity; Aza; 5-Aza-2â²-deoxycytidine; BBP; Butyl benzyl phthalate; DEG; Differentially expressed gene; DMR; Differentially methylated region; Fads1; Fatty acid desaturas
Keywords: 5-Aza-2'-deoxycytidine; HDAC; histone deacetylase; TSA; trichostain A; AZA; 5-Aza-2â²-deoxycytidine; Met; methionine; FA; folic acid; LPS; lipopolysaccharide; PBMC; peripheral blood mononuclear cells; HAT; histone acetylase; SAM; S-adenosylmethionine; DNMT; DNA methyltransferas
Keywords: 5-Aza-2'-deoxycytidine; TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: 5-Aza-2'-deoxycytidine; Runx2; Runt-related transcription factor 2; SPARC; secreted protein acidic and rich in cysteine; dAza; 5-aza-2â²-deoxycytidine; PPARγ; Peroxisome proliferator activated receptor γ; ROI; regions of interest; PTEN; phosphatase and tensin homolog; ME; mic
Keywords: 5-Aza-2'-deoxycytidine; H. pylori; Helicobacter pylori; CGI; CpG islands; 5-Aza-dC; 5-aza-2â²-deoxycytidine; TSS; transcription start site; Epigenetics; Chromatin remodeling; DNA methylation; Field defect;
Keywords: 5-Aza-2'-deoxycytidine; 5-aza-CdR; 5-aza-2â²-deoxycytidine; AML; acute myeloid leukemia; ANRIL; antisense non-coding RNA in the INK4 locus; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A; CoREST; co-repressor for element-1-silencing transcription factor
Keywords: 5-Aza-2'-deoxycytidine; HIF1/HIF-1; hypoxia inducible factor-1; VHL; von Hippel-Lindau; HRE; hypoxia response element; CBP; CREB binding protein; MBD; methyl-CpG binding domain; SRA; SET and RING finger-associated; KBS; Kaiso binding site; ANOVA; analysis of variance; FDR; fal
Keywords: 5-Aza-2'-deoxycytidine; Acetylcholinesterase; AChE antisense RNA; Epigenetic modulation; Apoptosis; Cis-platin; Mitomycin C; AChE; acetylcholinesterase; S-AChE; synaptic acetylcholinesterase; R-AChE; read-through acetylcholinesterase; E-AChE; erythrocyte acetylcholinesterase; AZ
Keywords: 5-Aza-2'-deoxycytidine; ECMs; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β1; transforming growth factor-β1; Ang-II; angiotension II; DNMTs; DNA methyltransferases; 5-Aza-dC; 5-Aza-2â²-deoxycytidine; EZH2; Enhancer of zeste homolog 2; HDAC; histone deacetylases;
Keywords: 5-Aza-2'-deoxycytidine; Treg; Regulatory T cells; Aza; 5-Aza-2â²-deoxycytidine; DNMT; DNA methyltransferase; MLR; Mixed leukocyte reaction; FCM; Flow cytometry; CD4+CD25+ Treg cell; IL-35; Decitabine; Cardiac allograft;
Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications
Keywords: 5-Aza-2'-deoxycytidine; Mouse embryonic stem cells; Endoderm hepatic specification; Endothelial cells; VEGFR2; Epigenetic modifications; ESC; human embryonic stem cell; EB; embryoid body; AL End; mouse ESC-derived endoderm cells cultured alone; CC End; mouse ESC-derived endoderm
ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells
Keywords: 5-Aza-2'-deoxycytidine; ETV7; Ets Variant Gene 7; ETS; E26 Transformation-Specific; DNAJC15; DNAJ Heat Shock Protein family (Hsp40) member C15; ABCB1; ATP Binding Cassette subfamily B member 1; DNMT3A; DNA Methyl-Transferase 3A; 5-Aza; 5-Aza-2â²-deoxycytidine; TNBC; Triple Nega
The role of DNA methylation in coronary artery disease
Keywords: 5-Aza-2'-deoxycytidine; (5Aza); 5-aza-2â²-deoxycytidine; (ACAT1); acetyl-CoA acetyltransferase 1; (ACS); acute coronary syndrome; (ApoE); Apolipoprotein E; (ABCA1); ATP-binding cassette A1; (BDNF); brain-derived neurotrophic factor; (CNKI); China National Knowledge Infrastructu
Hypericin inhibits hepatitis C virus replication via deacetylation and down-regulation of heme oxygenase-1
Keywords: 5-Aza-2'-deoxycytidine; Hepatitis C virus (HCV); Hypericin; Epigenetic; Deacetylation; HCV; Hepatitis C virus; NS5A; non-structure protein 5A; NS3; non-structure protein 3; HO-1; heme oxygenase 1; 5-Aza-dC; 5-aza-2â²-deoxycytidine; DAAs; direct acting antivirals; PCR; polymeras
Loss of c-KIT expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by KIT gene promoter DNA hypermethylation
Keywords: 5-Aza-2'-deoxycytidine; Breast Cancer; c-KIT; Epigenetics; DNA methylation; Immunohistochemistry; ADH; Atypical ductal hyperplasia; BCA; Bicinchoninic acid; CML; Chronic myelogenous leukemia; CK5/6; Cytokeratin 5/6; CK903; Cytokeratin 903; DCIS; Ductal Carcinoma in situ; ER; Est
DNMT1 mediated promoter methylation of GNAO1 in hepatoma carcinoma cells
Keywords: 5-Aza-2'-deoxycytidine; HCC; hepatic celluler cancer; GNAO1; Guanine nucleotide-binding protein α1; BSP; bisulfite sequence PCR; DAC; 5-Aza-2â²-deoxycytidine; TSA; Trichostatin A; DNMT-1; DNA methyltransferase 1; TGF-β; transforming growth factor β; Src; steroid receptor cof
Integrated data analysis identifies potential inducers and pathways during the endothelial differentiation of bone-marrow stromal cells by DNA methyltransferase inhibitor, 5-aza-2â²-deoxycytidine
Keywords: 5-Aza-2'-deoxycytidine; 5-aza-dC; 5-aza-2â²-deoxycytidine; ac-LDL; acetylated low-density lipoprotein; ANGPT; Angiopoietin; BMSCs; Bone-Marrow Stromal Cells; BSP; Bisulfite sequencing PCR; CD31/PECAM1; Platelet and endothelial cell adhesion molecule 1; CD105/ENG; Endoglin; eNOS
Epigenetic silencing of SFRP5 promotes the metastasis and invasion of chondrosarcoma by expression inhibition and Wnt signaling pathway activation
Keywords: 5-Aza-2'-deoxycytidine; SFRP5; Methylation; 5-Aza-2â²-deoxycytidine; Wnt/β-catenin pathway; Chondrosarcoma;
Neuronal Growth Factor regulates Brain Specific Kinase 1 expression by inhibiting promoter methylation and promoting Sp1 recruitment
Keywords: 5-Aza-2'-deoxycytidine; NGF; DNA methylation; Brsk1; DNMT3B; MAPK; 5â²Aza-dC; 5-aza-2â²-deoxycytidine; AKT/PKB; Protein kinase B; BRSK 1/2; Brain-Specific Kinase 1/2; C-5; cytosine 5'; CNS; Central Nervous System; DNMT; DNA methyltransferase; EMSA; Electrophoretic Mobility S
5-aza-2â²-deoxycytidine Inhibits the Proliferation of Lung Fibroblasts in Neonatal Rats Exposed to Hyperoxia
Keywords: 5-Aza-2'-deoxycytidine; bronchopulmonary dysplasia; lung interstitial fibrosis; P16 gene; 5-aza-2â²-deoxycytidine;
Cadmium-induced malignant transformation of rat liver cells: Potential key role and regulatory mechanism of altered apolipoprotein E expression in enhanced invasiveness
Keywords: 5-Aza-2'-deoxycytidine; IARC; International Agency for Research on Cancer; ApoE; Apolipoprotein E; LXR; liver X receptor; LXRE; liver X receptor response element; 5-aza-dC; 5-aza-2â²-deoxycytidine; ABCA1; ATP-binding cassette transporter; SREBP-1c; sterol regulatory element-bin
Original ArticleBCLB, methylated in hepatocellular carcinoma, is a starvation stress sensor that induces apoptosis and autophagy through the AMPK-mTOR signaling cascade
Keywords: 5-Aza-2'-deoxycytidine; BCLB; Tumor suppressor gene; Methylation; Apoptosis; Autophagy; TSGs; tumor suppressor genes; HCC; hepatocellular carcinoma; MEM; minimum essential medium; DMEM; Dulbecco's Modified Eagle's Medium; 5-Aza; 5-aza-2â²-deoxycytidine; TSA; trichostatin A; MSP
Determinants of orofacial clefting II: Effects of 5-Aza-2â²-deoxycytidine on gene methylation during development of the first branchial arch
Keywords: 5-Aza-2'-deoxycytidine; 1-BA; first branchial arch; AzaD; 5-Aza-2â²-deoxycytidine; CGI; CpG island; CM; complete media; CP; cleft palate; CL/P; cleft lip with or without cleft palate; GD; gestational day; IPA; ingenuity pathway analysis; MCS; MethylCap-sequencing; MEMM; mouse e
5-Aza-2â²-deoxycytidine induces human Tenon's capsule fibroblasts differentiation and fibrosis by up-regulating TGF-β type I receptor
Keywords: 5-Aza-2'-deoxycytidine; 5-Aza-2â²-deoxycytidine; DNA methylation; TGF-β type I receptor; Human Tenon's fibroblasts; Differentiation;
DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies
Keywords: 5-Aza-2'-deoxycytidine; DNMT; DNA methyltransferase; 5azadC; 5-aza-2â²-deoxycytidine; 5azaC; 5-azacytidine; SAM; S-adenosyl-l-methionine; SAH; S-adenosyl-l-homocysteine; DNMTi; DNMT inhibitors; HDACi; histone deacetylase inhibitors; CpGs; 5â²-CpG-3â² dinucleotides; CGis; CpG
Determinants of orofacial clefting I: Effects of 5-Aza-2â²-deoxycytidine on cellular processes and gene expression during development of the first branchial arch
Keywords: 5-Aza-2'-deoxycytidine; aCasp3; anti-activated caspase 3; aPH3; anti-phosphohistone H3; 1-BA; first branchial arch; AzaD; 5-Aza-2â²-deoxycytidine; CGI; CpG island; CP; cleft palate; CL/P; cleft lip with or without cleft palate; DAPI; 4â²-6â²-diamidino-2-phenylindole; FBS; fet
Targeting vasa vasorum dysfunction to prevent atherosclerosis
Keywords: 5-Aza-2'-deoxycytidine; Vasa vasorum; Atherosclerosis; Neoangiogenesis; Endothelial metabolism; Epigenetic regulation; microRNA; 5-aza-2â²-dC; 5-aza-2â²-deoxycytidine; BRD4; bromodomain-containing protein 4; BET; bromodomain and extra terminal domain; CAMs; cell adhesion molec
Inhibition of DNA Methylation in the COL1A2 Promoter by Anacardic Acid Prevents UV-Induced Decrease of Type I Procollagen Expression
Keywords: 5-Aza-2'-deoxycytidine; 5-AZA-dc; 5-AZA-2â²-deoxycytidine; AA; anacardic acid; bp; base pair; ChIP; chromatin immunoprecipitation; CPG; 5â²-cytosine-phosphate-guanine-3â²; DNMT; DNA methyltransferase; HAT; histone acetyltransferase; HDF; human dermal fibroblast; MMP; matrix m
Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer
Keywords: 5-Aza-2'-deoxycytidine; 5-aza-dC; 5-aza-2â²-deoxycytidine; AA; arachidonic acid; ADT; androgen deprivation therapy; AR; androgen receptor; BCR; biochemical recurrence; ChIP; chromatin immunoprecipitation; CNA; copy number alteration; COX; cyclooxygenase/prostaglandin G2/H2 synt
MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/β-Catenin and MYOD1/Caspase-3 Signaling Pathways
Keywords: 5-Aza-2'-deoxycytidine; AJCC; American Joint Committee on Cancer; Aza; 5-aza-2â²-deoxycytidine; ChIP-Seq; chromatin immunoprecipitation sequencing; DMSO; dimethyl sulphoxide; DTGs; direct target genes; FFPE; Formaldehyde-fixed paraffin-embedded; GC; gastric cancer; MBD; methyl-
Epigenetic regulation of CFTR in salivary gland
Keywords: 5-Aza-2'-deoxycytidine; CFTR; Salivary glands; Organ culture; 5-Aza-2â²-deoxycytidine; Epigenetic regulation; DNA methylation;
Simultaneous quantitative determination of 5-aza-2â²-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors
Keywords: 5-Aza-2'-deoxycytidine; 5-Aza-2â²-deoxycytidine; Decitabine; DNA methyltransferase inhibitor; LC/MS/MS; Genomic DNA; Global DNA demethylation; 5-Methyl-2â²-deoxycytidine; 5-Methylcytosine;
Frequent inactivation of MCC/CTNNBIP1 and overexpression of phospho-beta-cateninY654 are associated with breast carcinoma: Clinical and prognostic significance
Keywords: 5-Aza-2'-deoxycytidine; BC; breast carcinoma; ER; estrogen receptor; PR; progesterone receptor; TNBC; triple negative breast cancer; Her2; human epidermal growth factor receptor 2; UICC; International Union Against Cancer; TNM; tumor size, lymph node, metastasis; MA; microsatell
Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA
Keywords: 5-Aza-2'-deoxycytidine; 5-aza-dC; 5-aza-2â²-deoxycytidine; AD; Alzheimer's disease; AMD; Age-related Macular Degeneration; APOE; apolipoprotein E; ARPE-19; retinal pigmented epithelium cell line; ATP; adenosine triphosphate; BSA; bovine serum albumin; DMEM; Dulbecco's modified
MiR-143 and miR-135 inhibitors treatment induces skeletal myogenic differentiation of human adult dental pulp stem cells
Keywords: 5-Aza-2'-deoxycytidine; DPSCs; dental pulp stem cells; MSCs; mesenchymal stem cells; 5-Aza; 5-aza-2â²-deoxycytidine; GRMD; golden retriever muscular dystrophy; MEF2C; myocyte-specific enhancer factor 2C; MyoD; myogenic differentiation antigen; MyHC; myoglobin heavy chain; IMDM;
Effect of 5-Aza-2â²-deoxycytidine on Odontogenic Differentiation of Human Dental Pulp Cells
Keywords: 5-Aza-2'-deoxycytidine; 5-Aza-2â²-deoxycytidine; dental pulp cells; DNA methylation; odontogenic differentiation;
Perinatal nicotine exposure suppresses PPARγ epigenetically in lung alveolar interstitial fibroblasts
Keywords: 5-Aza-2'-deoxycytidine; α-SMA; Alpha smooth muscle actin; ATII; Alveolar epithelial type II; Aza-CdR; 5-Aza-2â²-deoxycytidine; ChIP; Chromatin immunoprecipitation; DMSO; Dimethyl sulfoxide; DNMT1; DNA methyltransferase 1; LIFs; Lipofibroblasts; MSP; Methylation-specific-PCR; M
Metabolomic analysis revealed the role of DNA methylation in the balance of arachidonic acid metabolism and endothelial activation
Keywords: 5-Aza-2'-deoxycytidine; AA; arachidonic acid; COX; cyclooxygenases; LOX; lipoxygenases; CYP; cytochrome P450; EETs; epoxyeicosatrienoic acids; HETEs; hydroxyeicosatetraenoic acids; PGs; prostaglandins; PGD2; prostaglandin D2; PTGDS; prostaglandin D2 synthase; TXB2; thromboxane B
Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells
Keywords: 5-Aza-2'-deoxycytidine; 5-Aza; 5-Aza-2â²-deoxycytidine; α-CTF; α-C-terminal fragment; β-CTF; β-C-terminal fragment; AD; Alzheimer's disease; APP; amyloid precursor protein; ASBI; APP-selective BACE1 inhibitor; Aβ; β-amyloid; BACE1; β-site amyloid precursor protein-clea
Novel aberrant genetic and epigenetic events in Friedreich׳s ataxia
Keywords: 5-Aza-2'-deoxycytidine; FRDA; Friedreich׳s ataxia; FXN; frataxin; ISC; iron-sulphur cluster; hPDL; human periodontal ligament; CASP3; active caspase-3; DNMT; DNA methyltransferase; CpG; cytosine phosphate group guanine; TSS; transcription start site; UP; upstream GAA repetiti
Research ArticleMicroRNA-221 governs tumor suppressor HDAC6 to potentiate malignant progression of liver cancer
Keywords: 5-Aza-2'-deoxycytidine; HCC; hepatocellular carcinoma; HDAC6; histone deacetylases 6; miRNA; microRNA; 5-aza; 5-aza-2â²-deoxycytidine; TSA; trichostatin A; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; UTR; u
Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation
Keywords: 5-Aza-2'-deoxycytidine; 5-Aza-dC; 5-Aza-2â²-deoxycytidine; AR; androgen receptor; DMSO; dimethyl sulfoxide; DNMT; DNA methyltransferase; ER-β; estrogen receptor beta; FOXO-1; forkhead box O-1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MBD; methyl binding domain; MSP; me
Structural perspective of ARHI mediated inhibition of STAT3 signaling: An insight into the inactive to active transition of ARHI and its interaction with STAT3 and importinβ
Keywords: 5-Aza-2'-deoxycytidine; ARHI; Aplasia Ras Homologue member I; STAT3; Signal Transducer and Activator of Transcription 3; NTD; N-terminal domain; CCD; Coiled-coil domain; DBD; DNA binding domain; LD; Linker domain; SH2; Src-homology-2 domain; TAD; transactivation domain; LOH; los
Secreted phospholipases A2 are differentially expressed and epigenetically silenced in human breast cancer cells
Keywords: 5-Aza-2'-deoxycytidine; DAC; 5-aza-2â²-deoxycytidine; HDACi; histone deacetylase inhibitor; TF; transcription factor; TSA; trichostatin A; TSS; transcription start site; DNA methylation; Epigenetics; Histone acetylation; Secreted phospholipase A2; Lipid signalling; Breast cance
Wnt inhibitory factor-1 functions as a tumor suppressor through modulating Wnt/β-catenin signaling in neuroblastoma
Keywords: 5-Aza-2'-deoxycytidine; WIF-1; Wnt inhibitory factor-1; MSP; methylation-specific PCR; 5-Aza-dC; 5-Aza-2â²-deoxycytidine; IHC; immunohistochemistry assay; IF; immunocytofluorescence assay; ICC; immunocytochemistry assay; Neuroblastoma; Wnt inhibitory factor-1 (WIF-1); Wnt/β-ca
B cell CLL/lymphoma 6 member B inhibits hepatocellular carcinoma metastases in vitro and in mice
Keywords: 5-Aza-2'-deoxycytidine; 5-Aza; 5-aza-2â²-deoxycytidine; 7-AAD; 7-aminoactinomycin D; BCL6B; B cell CLL/lymphoma 6 member B; cDNA; complementary DNA; FACS; fluorescence-activated cell sorting; DMEM; Dulbecco's modified Eagle medium; HCC; hepatocellular carcinoma; HTATIP2; HIV-1
SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages
Keywords: 5-Aza-2'-deoxycytidine; RAW264.7 mouse macrophage cell line; Suppressors of cytokine signaling1 (SOCS1); Hypermethylation; DNA methyltransferase1 (DNMT1); Pro-inflammatory cytokines; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IL-6; interleukin 6; SOCS; suppressor
Re-expression and epigenetic modification of maspin induced apoptosis in MCF-7 cells mediated by myocardin
Keywords: 5-Aza-2'-deoxycytidine; DNMT; DNA methyltransferase; 5-aza-dc; 5-aza-2â²-deoxycytidine; HDAC; histone deacetylase; TSA; Trichostatin A; serpin; serine protease inhibitor; DMEM; Dulbecco's modified Eagle's medium; EB; ethidium bromide; PS; phosphatidylserine; TUNEL; terminal deo
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts
Keywords: 5-Aza-2'-deoxycytidine; H2-DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; 5-Aza; 5-aza-2â²-deoxycytidine; 5-mC; 5-methylcytosine; ATF; activating transcription factor; AID; activation-induced deaminase; AGE; advanced glycation end-product; ARC; age-related cataract; A