Keywords: Vortioxetine (PubChem CID 9966051); Paroxetine (Pubmed CID 43815); 8-OH-DPAT (PubChem CID 1220); Flesinoxan (PubChem CID 57347); CP-94253 (PubChem CID 4029677); Ondansetron (PubChem CID 4595); Vortioxetine; 5-HT1A; 5-HT1B; 5-HT3; Male rat sexual behavior;
مقالات ISI (ترجمه نشده)
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Keywords: Pearl; Nacre; Anticonvulsant; Sedative–hypnotic; 5-HT3; GABAB
Keywords: OCD; Low-dose ondansetron; Augmentation; 5-HT3;
Keywords: 5-HT3; 5-hydroxytryptamine; AM; Abdominal migraine; AP; Abdominal pain; CHW; Children's Hospital of Wisconsin; CT; Computed tomography; CVS; Cyclic vomiting syndrome; FAP; Functional abdominal pain; FGIDs; Functional gastrointestinal disorders; FHx; Famil
Keywords: 5-HT; 5-hydroxytryptamine; 5-HT1A; 5-hydroxytryptamine1A; 5-HT3; 5-hydroxytryptamine3; CBD; cannabidiol; CBDA; cannabidiolic acid; D2; dopamine2; DA; dopamine; i.p.; intraperitoneally; i.v.; intravenously; LiCl; lithium chloride; MCP; metoclopramide; OND;
Keywords: Neuroprotection; Retina; Excitotoxicity; Retinal ganglion cells; Tropisetron; Pig; ACh; acetylcholine; AEBSF; 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride; α7 nAChR; alpha7 nicotinic acetylcholine receptor; ANOVA; analysis-of-variance; EDTA; e
In vitro pharmacology of ambroxol: Potential serotonergic sites of action
Keywords: Ambroxol; Radioligand binding; Serotonin; Receptor; 5-HT3; 5-HT transporter; SERT;
The nicotinic receptor drug sazetidine-A reduces alcohol consumption in mice without affecting concurrent nicotine consumption
Keywords: Alcohol; Nicotine; Sazetidine-A; Consumption; Abstinence; Withdrawal; nAChR; nicotinic acetylcholine receptor; DA; dopamine; VTA; ventral tegmental area; NAc; nucleus accumbens; DHβE; dihydro-beta-erythroidine; 5-HT3; 5-hydroxytryptamine3; KO; gene knock
Yokukansan contains compounds that antagonize the 5-HT3 receptor
Keywords: Yokukansan; Yi-Gan San; Serotonin receptor; Ion channel; Antagonist; 5-HT3; 5-HT; 5-hydroxytryptamine or serotonin;
Modality selective roles of pro-nociceptive spinal 5-HT2A and 5-HT3 receptors in normal and neuropathic states
Keywords: In vivo electrophysiology; Ventral posterolateral thalamus; Spinal nerve ligation; Neuropathic pain; Descending facilitation; Serotonergic pain modulation; Ondansetron; Ketanserin; 5-HT2A; 5-HT3; CPM; conditioned pain modulation; R; receptor; RM; repeated
Ethanolic extract of the aerial parts of Passiflora cincinnata Mast. (Passifloraceae) reduces nociceptive and inflammatory events in mice
Keywords: Passifloraceae; Passiflora; Antinociceptive activity; Mechanisms of antinociception; Anti-inflammatory activity; TRP; transient potential receptor; L-arg; L-arginine; L-Noarg; NÏ-nitro-L-arginine; 5-HT3; serotoninergic receptor type 3; NO; nitric oxide;
Peripheral 5-HT3 mediates mirror-image pain by a cross-talk with acid-sensing ion channel 3
Keywords: Serotonin; Acid; 5-HT3; Mirror image pain; Acid-sensing ion channel 3;
The binding orientations of structurally-related ligands can differ; AÂ cautionary note
Keywords: Cys-loop; Ion channel; Receptor; Radioligand; 5-HT3; Agonist; Antagonist; Crystal; Binding; Granisetron; Tropisetron; Ligand; Structure; Synthesis; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryon
Contrasting effects of 5-HT3 receptor stimulation of the nucleus accumbens or ventral tegmentum on food intake in the rat
Keywords: Nucleus accumbens; Ventral tegmental area; Serotonin; 5-HT3; Food intake; Motivation;
Docking, characterization and investigation of β-cyclodextrin complexed with farnesol, an acyclic sesquiterpene alcohol, produces orofacial antinociceptive profile in experimental protocols
Keywords: 5-HT3; 5-hydroxytryptamine; ANOVA; analysis of variance; Ca2+; calcium; CDs; cyclodextrins; DSC; differential scanning calorimetry; DTG; derivative thermogravimetry; DZP; diazepam; FAR; farnesol; FTIR; Fourier transform infrared spectroscopy; i.p; intrape
Potential of α7 nicotinic acetylcholine receptor PET imaging in atherosclerosis
Keywords: 5-HT3; type of 5-hydroxytryptamine (serotonin) receptor; (125I-)αBTX; (125I-labeled) α-bungarotoxin; α-CT; α-contotoxin, α7 nAChR antagonist; AAA; abdominal aorta aneurysm; ACh; acetylcholine; AChE; acetylcholinesterase; AngII; angiotensin II therapy
The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT3 receptors
Keywords: 5-HT3; Cys-loop; Binding site; Ligand docking; Scopolamine; Muscarinic; Antagonist; Muscarinic; Anxiety; Cognition; Memory; Depression; Hippocampus; Amygdala;
Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex
Keywords: 2-arachidonoylglycerol (2-AG); c-Fos; Endocannabinoid; Insular cortex; Monoacylglycerol lipase (MAGL); Nausea; 2-AG; 2-arachidonoylglycerol; 5-HT3; 5-hydroxytryptamine 3; AEA; anandamide; CB; cannabinoid; CTA; conditioned taste avoidance; COX; cyclooxygen
Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action
Keywords: Depression; Serotonin; 5-HT1A; 5-HT2A; 5-HT3; 5-HT7; 2-methoxyphenylpiperazine; Forced swim test
Original ResearchFull Report: Clinical-Alimentary TractRamosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women
Keywords: 5-Hydroxytryptamine-3-Receptor Antagonist; Abdominal Pain; Discomfort; 5-HT; BSFS; Bristol Stool Form Scale; CI; confidence interval; FDA; Food and Drug Administration; 5-HT; 5-hydroxytryptamine; 5-HT3; 5-hydroxytryptamine receptor 3; IBS; irritable bow
Aggression and anxiety in adolescent AAS-treated hamsters: A role for 5HT3 receptors
Keywords: Adolescence; AAS; Serotonin; 5-HT3; Aggression; Anxiety;
Evaluation of palonosetron and dexamethasone with or without aprepitant to prevent carboplatin-induced nausea and vomiting in patients with advanced non-small-cell lung cancer
Keywords: AUC; area under the curve; CINV; chemotherapy-induced nausea and vomiting; ECOG; Eastern Cooperative Oncology Group; HEC; highly emetogenic chemotherapy; 5-HT3; 5-hydroxytryptamine-3; MEC; moderately emetogenic chemotherapy; NK-1; neurokinin-1; NSCLC; non
Mechanisms and latest clinical studies of new NK1 receptor antagonists for chemotherapy-induced nausea and vomiting: Rolapitant and NEPA (netupitant/palonosetron)
Keywords: AE; adverse event; AUC; area under the curve; 5-HT3; serotonin subtype 3; CINV; chemotherapy-induced nausea/vomiting; Cmax; maximum serum concentration; CNS; central nervous system; CR; complete response; CYP; cytochrome P450; ECG; electrocardiogram; FLIE
Imidacloprid and thiacloprid neonicotinoids bind more favourably to cockroach than to honeybee α6 nicotinic acetylcholine receptor: Insights from computational studies
Keywords: nAChR; nicotinic acetylcholine receptor; Ac-AChBP; Aplysia californica-acetylcholine binding protein; LGICs; ligand-gated ion channels; GABA; gamma-aminobutyric acid; 5-HT3; 5-hydroxytryptamine receptor subtype 3; CHARMM; Chemistry at Harvard Molecular Me
5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option
Keywords: Obsessive-compulsive disorder; HTR3A; HTR3B; HTR3C; HTR3D; HTR3E; 5-HT3; Serotonin; Symptom dimensions; Endophenotype; Visual memory; Visual organization;
The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptors
Keywords: Antagonist; Cys-loop; Ion channel; Radioligand; 5-HT3; Agonist; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HTBP; an AChBP mutant modified to
Reduced Chrna7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABAA receptor subunits
Keywords: 5-HT3; serotonin 3 receptor; BDNF; brain-derived neurotrophic factor; CHRNA7/Chrna7; gene (human/mouse) encoding the α7 nicotinic acetylcholine receptor; CREB; cAMP response element binding protein; DLPFC; dorsal lateral prefrontal cortex; DTT; dithiothr
Lack of interaction of endocannabinoids and 5-HT3 neurotransmission in associative fear circuits of the amygdala: Evidence from electrophysiological and behavioural experiments
Keywords: CB1; 5-HT3; Amygdala; Fear conditioning; Slice; IPSC
Recent developments in 5-HT3 receptor pharmacology
Keywords: 5-HT3; antagonist; agonist; competitive; non-competitive; binding site
Antidepressant Potential of 5-HT3 Receptor Antagonist, N-n- propyl-3-ethoxyquinoxaline-2-carboxamide (6n)
Keywords: 5-HT3; receptor antagonists; forced swim test; head twitch; reserpine; tail suspension test;
Regulation of respiratory-related hypoglossal motor output by α1 adrenergic and serotonin 5-HT3 receptor activation in isolated adult turtle brainstems
Keywords: Reptile; Chelonian; Turtle; Episodic breathing; Respiratory regularity; α1 adrenergic; 5-HT3;
The Haemonchus contortus UNC-49B subunit possesses the residues required for GABA sensitivity in homomeric and heteromeric channels
Keywords: 5-HT3; serotonin (5-hydroxytryptamine)-gated ion channel receptor; AChBP; acetylcholine binding protein; cRNA; copy RNA; LGIC; ligand-gated ion channels; MS-222; 3-aminobenzoic acid ethyl ester, methanesulphonate salt; nAChR; nicotinic acetylcholine recep
Fluorophore assisted light inactivation (FALI) of recombinant 5-HT3A receptor constitutive internalization and function
Keywords: 5-HT3; 5-hydroxytryptamine (serotonin) type 3 receptor; BBS; bungarotoxin binding sequence; BTX; α-bungarotoxin; FALI; fluorophore assisted light inactivation; HA; hemagglutinin; 5-Hydroxytryptamine type 3 (5-HT3) receptors; Fluorophore assisted light in
A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patients
Keywords: Schizophrenia; Endophenotype; 5-HT3; Continuous Performance Test; Sustained attention; HTR3
Calcium modulation of 5-HT3 receptor binding and function
Keywords: Serotonin; Cys-loop; Channel; Pore; Extracellular domain; Modulation; Calcium; 5-HT3; HEK 293; human embryonic kidney cell line 293; 5-HT; 5-hydroxytryptamine (serotonin); 5-HT3-R; 5-hydroxytryptamine receptor type 3;
Added ondansetron for stable schizophrenia: A double blind, placebo controlled trial
Keywords: Cognitive impairments; 5-HT3; Ondansetron; Schizophrenia
Differential mediation of descending pain facilitation and inhibition by spinal 5HT-3 and 5HT-7 receptors
Keywords: Serotonergic; Pain; Descending facilitation; Inhibition; 5-HT7; 5-HT3
Central 5-HT receptors in cardiovascular control during stress
Keywords: Serotonin; Psychological stress; Sympathetic; Brainstem; Heart rate; Arterial pressure; 5-HT1A; 5-HT2A; 5-HT3
Bronchodilating effect of combined therapy with ipratropium bromide and ondansetron in patients with COPD
Keywords: Drug combination; Combination bronchodilator; COPD; Bronchodilation; Ondansetron; 5-HT3; Ipratropium bromide
Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
Keywords: Stress; Gene; Strain; Mouse; Inbred; Serotonin; Serotonin transporter; Tryptophan hydroxylase; VMAT2; MAOA; 5-HT1A; 5-HT1B; 5-HT2A; 5-HT2C; 5-HT3; Prefrontal cortex; Hippocampus; Amygdala; Anxiety; Depression; Emergence test; Forced swim test; Restraint
Chemosensitivity of unmyelinated axons in isolated human gastric vagus nerve
Keywords: Unmyelinated axons; Vagus nerve; Excitability; nAChR; 5-HT3; TRPV1
5-HT2 and 5-HT3 receptors in the lateral parabrachial nucleus mediate opposite effects on sodium intake
Keywords: 5-HT3; 5-HT2; angiotensin II; thirst; NaCl intake; LPBNANG II, angiotensin II; CCK, cholecystokinin; DOCA, deoxycorticosterone acetate; LPBN, lateral parabrachial nucleus; LY-278,584, 1-methyl-N-[8-methyl-8-azabicyclo (3.2.1)-oct-3-yl]-1H-indazole-3-carbo
Differential action of anti-emetic drugs on defecation and emesis induced by prostaglandin E2 in the ferret
Keywords: Prostanoid; Emesis; Defecation; Ferret; NK1; 5-HT3;
Plasticity of synaptic transmission in autonomic ganglia
Keywords: ACh; acetylcholine; ACTH; adrenocorticotropic hormone; CaMKII; calcium calmodulin kinase II; CAP; compound action potential; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; CO; carbon monoxide; CNS; central nervous system; EPSC