دانلود مقالات ISI درباره 6-OHDA، 6-hydroxydopamine + ترجمه فارسی

اسید کافئیک باعث کاهش استرس اکسیداتیو، کمبود یادگیری و حافظه در ضایعات آزمایشگاهی ناشی از استرپتوزوتوسین در داخل مغز و اعصاب در موش صحرایی

Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer’s disease; ANOVA, analysis of Variance; Aβ, amyloid-beta; BSA, bovine serum albumin; Caffeic acid, 3,4-dihydroxycinnamic acid; DMSO, dimethylsulfoxide; DNPH, 2,4-dini

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

معکوس اثر سیمواستاتین بر کاهش تراکم گیرنده کانابینوئید 1 در مغز موشهای مبتلا به شکستگی 6 هیدروکسیدوپامین

Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; 2-AG, 2-arachidonoylglycerol; BDNF, brain derived neurotrophic factor; CB1, cannabinoid receptor type 1; Cg, cingulate cortex; CNS, central nervous system; CO2, carbon dioxide; Cpudl, caudate putamen dorsolateral; Cpum, caudate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی اثربخشی دیازپام در رفتار اضطرابی مانند موش های همی پارکونسونی

Investigation of diazepam efficacy on anxiety-like behavior in hemiparkinsonian rats

Keywords: 6-OHDA، 6-hydroxydopamine; LA, low anxiety; HA, high anxiety; 6-OHDA, 6-hydroxydopamine; EPM, elevated plus maze; MFB, medial forebrain bundle; OFT, open field test; PD, Parkinson’s disease; SNc, substantia nigra compactaAnxiolytic; Parkinson’s disease; Non-motor symptom; Elevated

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

افزایش ابتدای آزادسازی دوپامین در سینههای دو طرفه پس از یکبار تزریق لانتاکتی سستین یک طرفه، باعث چرخشهای متقاطع خود به خود در موشهای صحرایی

Early increase in dopamine release in the ipsilateral striatum after unilateral intranigral administration of lactacystin produces spontaneous contralateral rotations in rats

Keywords: 6-OHDA، 6-hydroxydopamine; α-Syn, α-synuclein; 3-MT, 3-methoxytyramine; 6-OHDA, 6-hydroxydopamine; Ach, acetylcholine; ANOVA, analysis of variance; COMT, catechol-O-methyltransferase; DA, dopamine; DAT, dopamine transporter; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanilic a

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

سی تی اسکلت به عنوان یک هدف درمان جدید برای اختلالات نابرابری عصبی

The cytoskeleton as a novel therapeutic target for old neurodegenerative disorders

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ABP, actin binding protein; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; Aβ, amyloid-β; Cdk5, cyclin-dependent kinase 5; CMT, Charcot-Marie-Tooth disease; CMT2, Charcot-Marie-Tooth

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

اثرات تعدیل کننده سدیم سالیسیلات بر عوامل مؤثر بر تجمع پروتئین در طی پاتولوژی بیماری پارکینسون ناشی از روتنون

Modulatory effects of sodium salicylate on the factors affecting protein aggregation during rotenone induced Parkinson’s disease pathology

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; BCIP, 5-bromo-4-chloro-3-indolyl phosphate; COX-2, cyclooxygenase-2; DTNB, 5,5-Dithiobis 2-Nitrobenzoic acid; ETC, electron transport chain; GFAP, glial fibrillary acidic protein; HSP, heat shock proteins; HSF-1, heat shock fact

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

فعالیت سوپاتالامیک و مونوآمین استرییتال توسط تحریک سوپالاتالوم مدولاسیون می شوند

The subthalamic activity and striatal monoamine are modulated by subthalamic stimulation

Keywords: 6-OHDA، 6-hydroxydopamine; 5-HIAA, 5-hydroxyindoleacetic acid; 6-OHDA, 6-hydroxydopamine; DA, dopamine; DOPAC, 3–4-dihydroxyphenylacetic acid; EDTA, ethylenediaminetetraacetic acid; FFT, fast Fourier transform; H2O2, hydrogen peroxide; HPLC, high-performance liquid chromatography;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

مدلسازی دیسکینزی در مدل های حیوانی بیماری پارکینسون

Modeling dyskinesia in animal models of Parkinson disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AIMs, abnormal involuntary movements; AMPA, 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid; DA, dopamine; DBS, deep brain stimulation; ERK1/2, extracellular signal-regulated kinase 1/2; GPe, external globus pallidus;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

اثر درمان مزمن با آنتاگونیست گیرنده آنژیوتانسین 1 نوع در سطوح دوپامین استرینیاتیک در موش صحرایی و در یک مدل موش صحرایی از بیماری پارکینسون تحت درمان با لیپیدفا

Effect of chronic treatment with angiotensin type 1 receptor antagonists on striatal dopamine levels in normal rats and in a rat model of Parkinson's disease treated with l-DOPA

Keywords: 6-OHDA، 6-hydroxydopamine; Angiotensin; Candesartan; l-DOPA; Neuroprotection; Parkinson; Serotonin5-HIAA, metabolite 5-hydroxyindolacetic acid; 5-HT, serotonin; 6-OHDA, 6-hydroxydopamine; AII, angiotensin II; AT1, angiotensin type-1 receptor; AT2, angiotensin type-2 receptor; AUC,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

اثرات تحریک کننده و انگیزشی الکل: درس های مدل های جوندگان و پریمات

Stimulant and motivational effects of alcohol: Lessons from rodent and primate models

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ADH, alcohol dehydrogenase; ALDH, acetaldehyde dehydrogenase; BAC, blood alcohol concentration; BAES, Biphasic Alcohol Effects Scale; B-BAES, Brief Biphasic Alcohol Effects Scale; BXD RI, recombinant inbred mice; COF, consume of

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

اثرات متوقف کردن یک رژیم غذایی با چربی بالا بر پروتئین های میتوکندریایی و کاهش سدیم دوپامین ناشی از 6 هیدروکسی دیوپامین در موش صحرایی

Effects of discontinuing a high-fat diet on mitochondrial proteins and 6-hydroxydopamine-induced dopamine depletion in rats

Keywords: 6-OHDA، 6-hydroxydopamine; PD, Parkinson’s disease; DA, dopamine; 6-OHDA, 6-hydroxydopamine; PGC-1α, peroxisome proliferator-activated receptor-γ coactivator 1α; AMPK, AMP-activated protein kinase; pAMPK, phospho-AMP-activated protein kinase; TCF11/Nrf1, transcription factor 11/Nuc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Neurosteroid allopregnanolone attenuates cognitive dysfunctions in 6-OHDA-induced rat model of Parkinson’s disease

Keywords: 6-OHDA، 6-hydroxydopamine; PD, Parkinson’s disease; Allo, allopregnanolone; 6-OHDA, 6-hydroxydopamine; MWM, Moris water maze; NOR, novel object recognition; TH, thyrosin hydroxylase; SGZ, hippocampal subgranular zone; MPTP, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine; EGF, epid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity

Keywords: 6-OHDA، 6-hydroxydopamine; Hydroxytyrosol; Parkinson's disease; Dopamine; Oxidative stressPD, Parkinson's disease; DA, Dopamine; DAQ, Dopamine quinone; HT, Hydroxytyrosol; SF, Sulforaphane; 6-OHDA, 6-Hydroxydopamine; MPP+, 1-Methyl-4-phenylpyridinium; ROS, Reactive oxygen species;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Overexpression of α-synuclein simultaneously increases glutamate NMDA receptor phosphorylation and reduces glucocerebrosidase activity

Keywords: 6-OHDA، 6-hydroxydopamine; α-syn, α-synuclein; CMA, chaperone-mediated autophagy; GBA, glucosidase beta acid; GCase, glucocerebrosidase; GFP, green fluorescent protein; NMDAR, N-methyl-d-aspartate receptor; 6-OHDA, 6-hydroxydopamine; PD, Parkinson’s disease; TH, tyrosine hydroxylas

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; CNS, central nervous system; CSF, cerebrospinal fluid; IGF-1, insulin-like growth factor-1; IR, insulin receptor; METH, methamphetamine; NTFs, neurotrophic factors; PD, Parkinson’s disease; PFA, paraformaldehyde; SN, substantia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Striatal mRNA expression patterns underlying peak dose l-DOPA-induced dyskinesia in the 6-OHDA hemiparkinsonian rat

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AIM, abnormal involuntary movements; ANOVA, analysis of variance; LTP, long term potentiation; PD, Parkinson’s disease; SNc, substantia nigra pars compactaRNA-seq; dyskinesia; 6-OHDA; l-DOPA; striatum; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

l-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AADC, aromatic amino acid decarboxylase; AIM, abnormal involuntary movements; ANOVA, Analysis of Variance; DA, dopamine; ISH, in situ hybridization; l-DOPA, l-3,4-Dihydroxyphenylalanine; LID, l-DOPA-induced dyskinesia; mfb, medi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

New therapeutic opportunities for 5-HT2C receptor ligands in neuropsychiatric disorders

Keywords: 6-OHDA، 6-hydroxydopamine; 5-HT receptors; mRNA editing; G protein coupled receptors; Receptor oligomers; Dopamine; GABA5-HT2C receptor, serotonin2C receptor; DRN, dorsal raphe nucleus; MRN, medial raphe nucleus; DA, Dopamine; 6-OHDA, 6-hydroxydopamine; MPTP, 1-methyl-4-phenyl-1,2,

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

MIF-1 and its peptidomimetic analogs attenuate haloperidol-induced vacuous chewing movements and modulate apomorphine-induced rotational behavior in 6-hydroxydopamine-lesioned rats

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ADTN, 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene; DA, dopamine; EPS, extrapyrimidal side effects; HP, haloperidol; IP, intraperitoneally; MIF-1, melanocyte-stimulating hormone release inhibiting factor-1; MPTP, 1-methyl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: A longitudinal in-vivo study

Keywords: 6-OHDA، 6-hydroxydopamine; 3-D, three-dimensional; 6-OHDA, 6-hydroxydopamine; 11C-CH3I, carbon-11 labeled methyliodide; 11C-DTBZ, carbon-11 labeled dihydrotetrabenazine; ANOVA, analysis of variance; BR, binding ratio; DA, dopamine; DAT, dopamine transporter; DMSO, dimethyl sulfoxid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Suppression effects of O-demethyldemethoxycurcumin on thapsigargin triggered on endoplasmic reticulum stress in SK-N-SH cells

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AD, Alzheimer's disease; ATF6, activating transcription factor 6; BiP, binding immunoglobulin protein; BSA, bovine serum albumin; CHOP, C/EBP homologous protein; CNS, central nervous system; DMSO, dimethyl sulfoxide; DNA, deoxyr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Alteration of enteric monoamines with monoamine receptors and colonic dysmotility in 6-hydroxydopamine–induced Parkinson's disease rats

Keywords: 6-OHDA، 6-hydroxydopamine; β-AR, β-adrenoceptor; DA, dopamine; DAT, dopamine transporter; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GI, gastrointestinal; 5-HT, 5-hydroxytryptamine; IR, immunoreactive; NE, norepinephrine; 6-OHDA, 6-hydroxydopamine; PD, Parkinson's disease; SN

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Serotonergic interaction between medial prefrontal cortex and mesotelencephalic DA system underlies cognitive and affective deficits in hemiparkinsonian rats

Keywords: 6-OHDA، 6-hydroxydopamine; 5,7-DHT, 5,7-dihydroxytryptamine; 5-HIAA, 5-hydroxyindoleacetic acid; 6-OHDA, 6-hydroxydopamine; DA, dopamine; dmPFC, dorsal mPFC; DOPAC, 3,4-dihydroxyphenylacetic acid; dSTR, dorsal striatum; EPM, elevated plus maze; FST, forced swim test; MDS, midbrain

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of nociceptive response to chemical, mechanical, and thermal stimuli in adolescent rats with neonatal dopamine depletion

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ADHD, attention-deficit hyperactivity disorder; ANOVA, analysis of variance; Fos-ir, c-Fos-immunoreactivity; LC, locus coeruleus; MAP, methamphetamine; SN, substantia nigra; TH, tyrosine hydroxylase; VTA, ventral tegmental arean

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Loss of Nogo-A-expressing neurons in a rat model of Parkinson’s disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ANOVA, analysis of variance; CB, calbindin; ChAT, choline acetyltransferase; CNS, central nervous system; CR, calretinin; DA, dopamine; DAB, diaminobenzidine; FG, fluorogold; GABA, γ-aminobutyric acid; GFAP, glial fibrillary aci

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Giant GABAA receptor mediated currents in the striatum, a common signature of Parkinson's disease in pharmacological and genetic rodent models

Keywords: 6-OHDA، 6-hydroxydopamine; FS, fast spiking interneuron; HFS, high frequency stimulation; LTS, low threshold spiking interneuron; MSN, medium spiny neuron; PINK 1, PTEN-induced putative kinase 1; 6-OHDA, 6-hydroxydopamine; STN, subthalamic nucleus; TAN, tonically active neuronGABA;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Decreased ipsilateral [123I]iododexetimide binding to cortical muscarinic receptors in unilaterally 6-hydroxydopamine lesioned rats

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ACh, Acetylcholine; AChEI, Acetylcholinesterase inhibitor; AD, Alzheimer’s dementia; DLB, Dementia with Lewy bodies; HC-3, Hemicholinium-3; MFB, Medial forebrain bundle; NBM, Basal nucleus of Meynert; PD, Parkinson’s disease; PD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; the ADAGIO study, the Attenuation of Disease Progression with Azilect Given Once-daily) study; CBZ, carbamazepine; curcumin, (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; the DATATOP Study, the Deprenyl an

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Upregulation of β1-adrenoceptors is involved in the formation of gastric dysmotility in the 6-hydroxydopamine rat model of Parkinson's disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; β-AR, β-adrenoceptor; cDNA, complementary DNA; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GE, gastric emptying; GI, gastrointestinal; IC50, half maximal inhibitory concentration; IR, immunoreactivity; mRNA, messenger RNA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of prelimbic 5-HT1A receptors produces antidepressant-like effects in a unilateral rat model of Parkinson’s disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ANOVA, analysis of variance; DA, dopamine; EAAC1-ir, EAAC1-immunoreactive; FST, forced swim test; MFB, medial forebrain bundle; mPFC, medial prefrontal cortex; PD, Parkinson’s disease; PrL, prelimbic; SNc, substantia nigra pars

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroprotection by 6-(methylsulfinyl)hexyl isothiocyanate in a 6-hydroxydopamine mouse model of Parkinson׳s disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; PD, Parkinson׳s disease; 6-MSITC, 6-(methylsulfinyl)hexyl isothiocyanate; TH, tyrosine hydroxylase; SN, substantia nigra; STR, striatum; GSH, glutathione; ROS, reactive oxygen speciesParkinson׳s disease; 6-hydroxydopamine; Neuro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Neurotrophic and neuroprotective efficacy of intranasal GDNF in a rat model of Parkinson’s disease

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; BBB, blood–brain barrier; BSA, bovine serum albumin; GDNF, glial cell line-derived neurotrophic factor; IOD, integrated optical density; MFB, median forebrain bundle; OVAL, ovalbumin; PBS, phosphate-buffered saline; PD, Parkinso

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Levodopa-induced dyskinesias are associated with transient down-regulation of cAMP and cGMP in the caudate-putamen of hemiparkinsonian rats: Reduced synthesis or increased catabolism?

Keywords: 6-OHDA، 6-hydroxydopamine; cAMP, cyclic adenosine monophosphate; cGMP, cyclic guanosine monophosphate; PDE, phosphodiesterase; 6-OHDA, 6-hydroxydopamine; PDE10A, phosphodiesterase 10A; PDE1B, phosphodiesterase 1BParkinson disease; Levodopa dyskinesia; cAMP; cGMP; Phopsphodiesterase

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Heterozygous mutations in the FGF8, SHH and nodal/transforming growth factor beta pathways do not confer increased dopaminergic neuron vulnerability—A zebrafish study

Keywords: 6-OHDA، 6-hydroxydopamine; fgf8, fibroblast growth factor 8; shh, sonic hedgehog; PD, Parkinson's disease; MPP+, 1-Methyl-4-phenyl-pyridinium; TGF-β, transforming growth factor beta; 6-OHDA, 6-hydroxydopamine; WISH, whole-mount in situ hybridization; TH, tyrosine hydroxylase; FWD,

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

5-HT1 receptor agonists for the treatment of L-DOPA-induced dyskinesia: From animal models to clinical investigation

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AIMs, Abnormal involuntary movements; DA, Dopamine; L-DOPA, L-3,4-dihydroxyphenylalanine; LID, L-DOPA-induced dyskinesia; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Partkinson's disease6-OHDA; Dopamine; Serotonin; L

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned mice

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AIMs, abnormal involuntary movements; ANOVA, analysis of variance; cdk5, cyclin-dependent kinase 5; CS, citrate synthase; DARPP-32, dopamine and cAMP-regulated phosphoprotein 32 kDa; DA, dopamine; EDTA, ethylenediaminetetraaceti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Beta oscillations in the cortico-basal ganglia loop during parkinsonism

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; BBO, beta band oscillations; CBG, cortico-basal ganglia; DBS, deep brain stimulation; GPe, globus pallidus externus; GPi, globus pallidus internus; LFP, local field potential; MPTP, 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Adaptive gene expression changes on the healthy side of parkinsonian rats

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; D1R, D1-class dopamine receptor; D2R, D2-class dopamine receptor; DAT, dopamine transporter; DYN, dynorphin; ENK, enkephalin; GABA, γ-aminobutyric acid; M1, primary motor cortex; MFB, medial forebrain bundle; NR, NMDA glutamater

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Delayed administration of zingerone mitigates the behavioral and histological alteration via repression of oxidative stress and intrinsic programmed cell death in focal transient ischemic rats

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ANOVA, Analysis of variance; Apaf-1, Apoptotic protease activating factor-1; ATP, Adenosine triphosphate; b.wt, Body weight; Bax, Bcl-2 associated X protein; Bcl-2, B-cell lymphoma-2; BSA, Bovine serum albumin; caspase, Cysteine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; DA, dopamine; DBS, deep brain stimulation; DOPAC, 3,4-dihydroxyphenylacetic acid; GABA, γ-aminobutyric acid; GPe, globus pallidus externa; GPi, globus pallidus interna; HPLC-EC, high performance liqiuid chromatography with coupl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Axon degeneration in Parkinson's disease

Keywords: 6-OHDA، 6-hydroxydopamine; [3H]TBZOH, tritiated α-dihydrotetrabenazine; 6-OHDA, 6-hydroxydopamine; AAV, adeno-associated virus; AD, Alzheimer's disease; AVs, autophagic vacuoles; DLB, dementia with Lewy Bodies; ILB, incidental Lewy bodies; LB, Lewy body; LRRK2, leucine rich repeat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

α4β2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats

Keywords: 6-OHDA، 6-hydroxydopamine; Dyskinesia; l-dopa; Nicotine; Nicotinic; Parkinson's disease; SazetidineAIMs, abnormal involuntary movements; ANOVA, analysis of variance; nAChRs, nicotinic receptors; CNS, central nervous system; α-CtxMII, α-conotoxinMII; 6-OHDA, 6-hydroxydopamine; 125I-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Alterations in the expression of nNOS in the substantia nigra and subthalamic nucleus of 6-OHDA-lesioned rats: The effects of chronic treatment with l-DOPA and the nitric oxide donor, molsidomine

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; CV, cresyl violet; NADPH-d, nicotinamide dinucleotide phosphate diaphorase; nNOS, neuronal nitric oxide synthase; NO, nitric oxide; MFB, medial forebrain bundle; mol, molsidomine; PD, Parkinson's disease; SNc, substantia nigra p

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Lipopolysaccharide-induced nigral inflammation leads to increased IL-1β tissue content and expression of astrocytic glial cell line-derived neurotrophic factor

Keywords: 6-OHDA، 6-hydroxydopamine; DA, dopamine; ELISA, enzyme linked immunosorbent assay; GDNF, glial cell lined-derived neurotrophic factor; GFAP, glial fibrillary acidic protein; 6-OHDA, 6-hydroxydopamine; IL-1b, interleukin 1 beta; IL-1ra, interleukin 1 receptor antagonist; iNOS, induc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; AIMs, abnormal involuntary movements; KPBS, potassium phosphate buffered saline; LID, L-DOPA-induced dyskinesia; MFB, medial forebrain bundle; PBS, phosphate buffered saline; PD, Parkinson's disease; SERT, serotonin transporter;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Key factors determining the efficacy of gene therapy for continuous DOPA delivery in the Parkinsonian brain

Keywords: 6-OHDA، 6-hydroxydopamine; 3-OMD, 3-methoxy-4-hydroxy-l-phenylalanine; 5-HT, serotonin; 5,7-DHT, 5,7-dihydroxytryptamine; 6-OHDA, 6-hydroxydopamine; AADC, aromatic l-amino acid decarboxylase; AAV, adeno-associated virus; BBB, blood–brain barrier; BH4, 5,6,7,8-tetrahydro-l-biopterin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Proteomic analysis reveals a protective role for DJ-1 during 6-hydroxydopamine-induced cell death

Keywords: 6-OHDA، 6-hydroxydopamine; 6-OHDA, 6-hydroxydopamine; ROS, reactive oxygen species; PD, Parkinson’s disease; SOD3, extracellular superoxide dismutase; 2-DE, 2-dimensional electrophoresis; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight; PYGB, glycogen phosphor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Portable microstimulator for chronic deep brain stimulation in freely moving rats

Keywords: 6-OHDA، 6-hydroxydopamine; DBS, deep brain stimulation; 6-OHDA, 6-hydroxydopamine; ODs, optical densities; PD, Parkinson's disease; STN, subthalamic nucleusImplantable device; High frequency stimulation; Electrode; Parkinson's disease; Rodent; Subthalamic nucleus

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Differential susceptibility to the PPAR-γ agonist pioglitazone in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine rodent models of Parkinson's disease

Keywords: 6-OHDA، 6-hydroxydopamine; MAO-B, monoamine oxidase-B; PPAR, peroxisome proliferator-activated receptor; SNc, substantia nigra pars compacta; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA, 6-hydroxydopamine; VTA, ventral tegmental area; TH, tyrosine hydroxylasePPAR; Pi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Full and partial peroxisome proliferation-activated receptor-gamma agonists, but not delta agonist, rescue of dopaminergic neurons in the 6-OHDA Parkinsonian model is associated with inhibition of microglial activation and MMP expression

Keywords: 6-OHDA، 6-hydroxydopamine; HPLC-ECD, High performance liquid chromatography-Electrochemical detection; 6-OHDA, 6-hydroxydopamine; mfb, medial forebrain bundle; PD, Parkinson's disease; SNc, substantia nigra pars compacta; PPAR, Peroxisome proliferator-activated receptor; MMP, matri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه