Keywords: Buspirone; Analgesia; Learning and memory; Serotonin 1A receptors; Hyperphagia; 5-HT; 5-hydroxytryptamine; 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino) tetralin;
مقالات ISI (ترجمه نشده)
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Keywords: BCA; bicinchoninic acid; BSA; bovine serum albumin; 8-OH-DPAT; 8-hydroxy-2(di-N-propylamino)tetralin; CHAPS; 3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate; CMC; critical micelle concentration; di-8-ANEPPS; 4-(2-(6-(dioctylamino)-2-naphthaleny
Membrane cholesterol oxidation in live cells enhances the function of serotonin1A receptors
Keywords: 5-HT1A receptor; 5-hydroxytryptamine-1A receptor; BCA; bicinchoninic acid; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DPH; 1,6-diphenyl-1,3,5-hexatriene; GTP-γ-S; guanosine-5â²-O-(3-thiotriphosphate); 8-OH-DPAT; 8-hydroxy-2(di-N-propylamino)tetr
Keywords: 5-HT; 5-hydroxytryptamine (serotonin); LFP; local field potential; MEC; medial entorhinal cortex; OIM; oscillatory interference model; navigation; theta; grid cells; 8-OH-DPAT; diazepam;
Keywords: 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino) tetralin; HFS; high-frequency stimulation; ACh; acetylcholine; BDNF; brain derived neurotrophic factor; BG; basal ganglia; CSF; cerebro-spinal fluid; DA; dopami
Keywords: 8-OH-DPAT; 8-hydroxy-2(di-N-propylamino)tetralin; BCA; bicinchoninic acid; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DPH; 1,6-diphenyl-1,3,5-hexatriene; GPCR; G protein-coupled receptor; GTP-γ-S; guanosine-5â²-O-(3-thiotriphosphate); PEtOH; phe
Keywords: 5-HT; 5-HT1A receptors; LTP; SPW-R; Fenfluramine; Citalopram; NAN-190; 8-OH-DPAT
Keywords: Electrophysiology; Event related potential; Hearing; Mouse; Serotonergic; Tone; 5-HT; 5-hydoxytryptamine, serotonin; 8-OH-DPAT; 8-hydroxy-DPAT hydrobromide, 5-HT1A receptor agonist; ABR; auditory brainstem response; AEP; auditory evoked potential; ANOVA;
Keywords: Serotonin; Depression; Neurodevelopment; Prenatal; Postnatal; Behavior; 5-HT; 5-hydroxytryptamine serotonin; SSRI; selective serotonin reuptake inhibitors; 5-MT; 5-methoxytryptamine; 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino) tetralin; CGS-120066B; 4-(4-me
Keywords: 5-HT; serotonin; 8-OH-DPAT; Dipropylamino-5,6,7,8-tetrahydronaphthalen-1-ol; AOB; accessory olfactory bulb; AVP; vasopressin; BNST; bed nucleus of the stria terminalis; CNS; central nervous system; EB; estradiol benzoate; ERα-IR; estrogen receptor-α imm
Keywords: ADL; activities of daily living; COMT; catechol-O-methyltransferase; DOI; 2,5-dimethoxy-4-iodoamphetamine; GIRK; G-protein-gated inwardly rectifying potassium; GP; globus pallidus; GPCR; G protein-coupled receptor; GPe; external segment of GP; GPi; intern
Keywords: 5-HT; serotonin; 5-HTTLDR; 5-HTT-linked polymorphic region; 5HIAA; 2-(5-hydroxy-1H-indol-3-yl)acetic acid; 8-OH-DPAT; 8-hydroxy-2-dipropylaminotetralin; ACTH; adrenocorticotrophic hormone; AID; agranular insular cortex; AVP; vasopressin; BAC; blood alcoho
Keywords: 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; Serotonin, 5-hydroxytryptamine; 5-HTP; 5-hydroxytryptophan; 8-OH-DPAT; 7-(Dipropylamino)-5,6,7,8-tetrahydronaphtalen-1-ol; AADC; Aromatic l-amino-acid decarboxylase (EC 4.1.1.28); ACTH; Adrenocorticotropic hormone
Breathing stimulation mediated by 5-HT1A and 5-HT3 receptors within the preBötzinger complex of the adult rabbit
Keywords: AU; arbitrary units; BötC; Bötzinger complex; BSA; bovine serum albumin; DLH; D, L-homocysteic acid; DMSO; dimethyl sulfoxide; 5-HT; serotonin; iVRG; inspiratory portion of the VRG; 8-OH-DPAT; (R)-(+)-8-Hydroxy-DPAT hydrobromide; PBG; 1-phenylbiguanide
The antipsychotic trifluoperazine reduces marble-burying behavior in mice via D2 and 5-HT2A receptors: Implications for obsessive-compulsive disorder
Keywords: DOI; (±)-2,5-dimethoxy-4-iodoamphetamine; 5-HT; serotonin; OCD; obsessive-compulsive disorder; 8-OH-DPAT; 8-hydroxy-2-(dipropylamino)tetralin; SERT; serotonin transporter; SRIs; serotonin reuptake inhibitors; SSRIs; selective serotonin reuptake inhibit
The influence of 5-HT1A receptors in the dorsal raphé nucleus on genioglossus activity
Keywords: DRN; dorsal raphé nucleus; ACSF; artificial cerebrospinal fluid group; 8-OH-DPAT; (±)-8-hydroxy-2-(dipropylamino); OSA; obstructive sleep apnea; CIH; chronic intermittent hypoxia; TMS; transcranial magnetic stimulation; IH; intermittent hypoxia; RMg; ra
Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD
Keywords: Aging; 8-OH-DPAT; Hypothermia; Cognition; Hippocampus; FADD;
Paternal Cocaine Disrupts Offspring Circadian Clock Function in a Sex-Dependent Manner in Mice
Keywords: 8-OH-DPAT; 8-hydroxy-n,n-dipropylaminotetralin; ANOVA; analysis of variance; BDNF; brain-derived neurotropic factor; CocSire; cocaine-sired offspring; CtlSire; control-sired offspring; DD; constant darkness; F1; first generation offspring; i.p; intraperit
The long-term effect of maternal dietary protein restriction on 5-HT1A receptor function and behavioral responses to stress in adulthood
Keywords: 5-HT; serotonin; PND; postnatal day; ED50; dose of drug that is pharmacologically effective for 50% of the population; Emax; concentration that produces the maximum possible response for that agonist; 8-OH-DPAT; 8-Hydroxy-2-(dipropylamino)tetralin hydrobr
A behavioral mechanistic investigation of the role of 5-HT1A receptors in the mediation of rat maternal behavior
Keywords: Serotonin; Serotonin 1A receptor; 8-OH-DPAT; WAY-101405; Pup preference; PPI and startle; Pup separation; Maternal behavior;
Further investigation of the effects of 5-hydroxytryptamine, 8-OH-DPAT and DOI to mediate contraction and relaxation responses in the intestine and emesis in Suncus murinus
Keywords: 5-Hydroxytryptamine; 8-OH-DPAT; DOI; 5-HT1A and 5-HT2 receptor subtypes; Suncus murinus intestine;
The GABAergic Gudden's dorsal tegmental nucleus: A new relay for serotonergic regulation of sleep-wake behavior in the mouse
Keywords: Serotonin; 5-HT1A receptor; Sleep-wake cycle; Gudden dorsal tegmental nucleus; Lateral mammillary nucleus; Rabies viral tracing; 3V; 3rd ventricle; 4V; 4th ventricle; 7n; facial nerve; 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino)-tetraline; aCSF; artificial
Sphingolipids modulate the function of human serotonin1A receptors: Insights from sphingolipid-deficient cells
Keywords: 5-HT1A receptor; 5-hydroxytryptamine-1A receptor; BCA; bicinchoninic acid; GTP-γ-S; guanosine-5â²-O-(3-thiotriphosphate); 8-OH-DPAT; 8-hydroxy-2(di-N-propylamino)tetralin; Nutridoma-BO; nutridoma-oleic acid-albumin complex; PMSF; phenylmethylsulfonyl fl
The effect of 8-OH-DPAT and dapoxetine on gene expression in the brain of male rats during ejaculation
Keywords: 8-OH-DPAT; Dapoxetine; Brain; Gene expression; Ejaculation; Male rats;
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes
Keywords: 5-HT1A receptor; α1-Adrenoceptor subtypes; D2-like receptor subtypes; Selective 5-HT1A receptor agonists; Docking studies; Anxiolytic effect; 5-HT; 5-hydroxytriptamine; GPCR; G protein-coupled receptor; TM; transmembrane; ARs; adrenoceptors; SAR; structu
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain
Keywords: Duloxetine; Fluoxetine; 8-OH-DPAT; Forced swimming test; Neuropathic pain; Depression;
Review ArticleA ventral root avulsion injury model for neurogenic underactive bladder studies
Keywords: 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino)-tetralin; CGRP; calcitonin gene-related peptide; CM/CE; conus medullaris/cauda equina; DU; detrusor underactivity; EMG; electromyography; EUS; external urethral sphincter; LUT; lower urinary tract; PPN; preganglio
Neuropeptide Y signaling in the dorsal raphe nucleus inhibits male sexual behavior in mice
Keywords: 5-HT; serotonin or 5-hyrodxytryptamine; 8-OH-DPAT; (±)-8-hydroxy-2-dipropylaminotetralin; DOI; (+)-DOI hydrochloride; DRN; dorsal raphe nucleus; MPOA; medial preoptic area; MRN; median raphe nucleus; NPY; neuropeptide Y; PBS; phosphate-buffered saline; T
An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells
Keywords: Serotonin transporter; Adrenal chromaffin cell; Calcium channel; Exocytosis; Catecholamine; 5-HT receptor; Amperometry; Calcium imaging; GPCR; 8-OH-DPAT; 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; DMSO; dimethyl sulfoxide; GIRK channel; G protei
Research PaperInfluence of urothelial or suburothelial cholinergic receptors on bladder reflexes in chronic spinal cord injured cats
Keywords: AMN; Atropine methyl nitrate; ATP; Adenosine triphosphate; 5-HT1A; Serotonergic receptor1A; 8-OH-DPAT; (±) 8-hydroxy-2-di-N-propylaminotetralin hydrobromide; BC; Bladder capacity; CMGs; Cystometrograms; MMP; Maximal micturition pressure; OXO-M; Oxotremor
MDMA-assisted therapy: A new treatment model for social anxiety in autistic adults
Keywords: 5HT1A; 5-hydroxytryptamine (serotonin) receptor 1A; 8-OH-DPAT; 7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; ADOS-2; Autism Diagnostic Observation Schedule, Second Edition (Module 4); BDI; Beck Depression Inventory; CAPS; Clinician-Administered PTS
Enhanced discriminative stimulus effects of Î9-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys
Keywords: Cannabinoid; Rhesus monkey; Drug discrimination; Cannabidiol; 8-OH-DPAT; Serotonin; 5-HT1A; Rimonabant; Dependence;
Serotonin 1A agonism decreases affiliative behavior in pair-bonded titi monkeys
Keywords: Pair-bonding; Oxytocin; Vasopressin; Cortisol; Monogamy; 8-OH-DPAT; Social behavior; Primate;
Effects of L-dopa priming on cortical high beta and high gamma oscillatory activity in a rodent model of Parkinson's disease
Keywords: 5-HT; serotonin; 6-OHDA; 6-hydroxydopamine; 8-OH-DPAT; (+)-8-hydroxy-2-(dipropylamino)tetralin hydrobromide; AIMs; abnormal involuntary movements; ALO; axial, limb, and orolingual; benserazide; dl-serine 2-(2,3,4-trihydroxybenzyl) hydrazide hydrochloride;
Sphingolipids in the function of G protein-coupled receptors
Keywords: 5-HT1A receptors; serotonin1A receptors; 8-OH-DPAT; 8-hydroxy-2(di-N-propylamino)tetralin; CCK receptor; cholecystokinin receptor; ER; endoplasmic reticulum; FB1; fumonisin B1; GM1; monosialotetrahexosylganglioside; GPCR; G protein-coupled receptor; GQ1b;
5-Hydroxytryptamine does not reduce sympathetic nerve activity or neuroeffector function in the splanchnic circulation
Keywords: 5-CT; 5-carboxamidotryptamine; 5-HT; 5-hydroxytryptamine; 8-OH-DPAT; (±)-8-hydroxy-2-dipropylaminotetralin; CP93129; 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one; EFS; electrical field stimulation; TTX; tetrodotoxin; 5-HT;
Medial prefrontal cortex serotonergic and GABAergic mechanisms modulate the expression of contextual fear: Intratelencephalic pathways and differential involvement of cortical subregions
Keywords: 5-HT; 5-hydroxytryptamine; 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino) tetralin; ACC; anterior cingulate cortex; ANOVA; analysis of variance; BDA; biotinylated dextran amine; Cg1; anterior cingulate cortex area 1; dH; dorsal hippocampus; FPS; fear-potentiat
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands
Keywords: Learning and memory; Passive avoidance; 5-HT1A receptors; MC18; 8-OH-DPAT;
Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice
Keywords: ASD; autism spectrum disorders; TSC; tuberous sclerosis complex; mTOR; mechanistic target of rapamycin; PTEN; phosphatase and tensin homolog; 5-HT; 5-hydroxytryptophan; SerT/Slc6a4; serotonin transporter; CaMKIIα; Ca2 +/calmodulin-dependent protein kina
Research reportBidirectional amygdaloid control of neuropathic hypersensitivity mediated by descending serotonergic pathways acting on spinal 5-HT3 and 5-HT1A receptors
Keywords: CeA; central nucleus of amygdala; i.t.; intrathecal; NMDA; N-methyl-d-aspartate; 8-OH-DPAT; 8-hydroxy-2-dipropylaminotetralin; RVM; rostral ventromedial medulla; Amygdala; Descending pain control; Neuropathic pain; Rostral ventromedial medulla; Serotonerg
Activation of 5-HT1A receptors in the preBötzinger region has little impact on the respiratory pattern
Keywords: 5-HT receptors; Control of breathing; Respiratory neurons; preBötzinger complex; 5-HT1A receptors; 8-OH-DPAT
Moderate Role of Oxytocin in the Pro-Ejaculatory Effect of the 5-HT1A Receptor Agonist 8-OH-DPAT
Keywords: 8-OH-DPAT; WAY-100635; Oxytocin; Ejaculation; Paraventricular Hypothalamic Nucleus;
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. Part 5
Keywords: Pyrido[1,2-c]pyrimidines; Antidepressants; Dual SSRI/5-HT1A activity; Quinoline derivatives; SERT; serotonin transporter; SAR; structure-activity relationship; 5-HT1AR; serotonin 5-HT1A receptors; 8-OH-DPAT; 8-hydroxy-2-(di-n-propylamino)tetralin; Ki; inh
Serotonergic 5-HT2A/2C receptors are involved in prolactin secretion in hyperestrogenic rats
Keywords: Hyperprolactinemia; Serotonin; MK212; 8-OH-DPAT; Pindolol; Hyperestrogenism;
Role of 5-HT1A- and 5-HT2A receptors for the murine model of the serotonin syndrome
Keywords: 5-HT; serotonin; 5-HTP; 5-hydroxy-l-tryptophan; 8-OH-DPAT; 8-hydroxy-N,N-dipropyl-2-aminotetralin hydrobromide; SS; serotonin syndrome; SRI; serotonin reuptake inhibitor; SSRI; selective serotonin reuptake inhibitor; TCB-2; 4-bromo-3,6-dimethoxybenzocyclo
Serotonin 1A receptors and sexual behavior in a genetic model of depression
Keywords: 5-HIAA; 5-hydroxyindoleacetic acid (5-HIAA metabolite of 5-HT); 5-HT; serotonin; CE; copulatory efficiency; E; ejaculation; EF; ejaculation frequency; EL; latency to the ejaculation; FRL; Flinders Resistant Line; FSL; Flinders Sensitive Line; I; intromiss
Stereospecific requirement of cholesterol in the function of the serotonin1A receptor
Keywords: 5-HT1A receptor; 5-hydroxytryptamine-1A receptor; 8-OH-DPAT; 8-hydroxy-2(di-N-propylamino)tetralin; BCA; bicinchoninic acid; CHAPS; 3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate; DMPC; dimyristoyl-sn-glycero-3-phosphocholine; DPH; 1,6-dipheny
Effects of (+)-8-OH-DPAT on the duration of immobility during the forced swim test and hippocampal cell proliferation in ACTH-treated rats
Keywords: Adrenocorticotropic hormone; 8-OH-DPAT; 5-HT1A receptor; Cyclin D1; Forced swim test; Cell proliferation
Cardiovascular pharmacologyThe role of the sympathetic nervous system in the resuscitative effect of stimulating the central serotonin 1A receptors in haemorrhagic shock in rats
Keywords: Hypovolaemia; Shock; Sympathetic nervous system; Serotonin; Serotonin 1A receptor; 8-OH-DPAT;
5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19
Keywords: GPCRs; G protein coupled receptors; RGS; regulator of G protein signaling; GAP; GTPase accelerating protein; RH; RGS homology domain; shRNA; short hairpin RNA; GFP; green fluorescent protein; IBMX; 3-isobutyl-1-methylxanthine; MAPK; mitogen-activated prot