دانلود مقالات ISI درباره Aβ + ترجمه فارسی

CD47 does not mediate amyloid-β(1-42) protofibril-stimulated microglial cytokine release

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; HFIP; hexafluoroisopropanol; IL-1β; interleukin-1β; SEC; size exclusion chromatography; ThT; thioflavin T; TNFα; tumor necrosis factor α; Amyloid-beta protein; A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain

Keywords: AD; Alzheimer's disease; ChAT; choline acetyltransferase; OLE; oleuropein aglycone; NBM; nucleus basalis magnocellularis; Aβ; amyloid β; NFT; neurofibrillary tangles; GFAP; glial fibrillary acid protein; Iba 1; ionized calcium binding adaptor molecule;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Estrogen receptor α promotes non-amyloidogenic processing of platelet amyloid precursor protein via the MAPK/ERK pathway

Keywords: Aβ; amyloid β peptide; APP; amyloid precursor protein; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease domain; BBB; blood brain barrier; ERα; estrogen receptor α; α-ERKO; estrogen receptor α knock-out; ERK; extracellular-signal-re

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells

Keywords: Aβ; amyloid beta peptide; AD; Alzheimer's disease; ADAM; A disintegrin and metalloproteinase; APOE; apolipoprotein E; APP; amyloid precursor protein; BACE1; beta-secretase; CHO; Chinese hamster ovary; CTF; C-terminal fragment; DN; dominant negative; FA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Tolfenamic acid downregulates BACE1 and protects against lead-induced upregulation of Alzheimer's disease related biomarkers

Keywords: Alzheimer's disease; Amyloid beta; BACE1; Pb; Sp1; Tolfenamic acid; Aβ; amyloid β; AD; Alzheimer's disease; ANOVA; analysis of variance; APP; amyloid β precursor protein; BACE; beta-site APP cleaving enzyme; FBS; fetal bovine serum; Pb; lead; SEM; stan

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Metallothionein-III increases ADAM10 activity in association with furin, PC7, and PKCα during non-amyloidogenic processing

Keywords: APP; amyloid precursor protein; MT-III; metallothionein-III; sAPPα; soluble APPα; AD; Alzheimer's disease; Aβ; amyloid-β; PC7; proprotein convertase7; PKC; protein kinase C; ADAM10; A-disintegrin and metalloproteinase 10; TGN; trans-Golgi network; T

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin

Keywords: ACh; acetylthiocholine iodide; AChE; acetylcholinesterase; AGEs; advanced glycation endproducts; AR; aldose reductase; ARI; aldose reductase inhibitor; AMT; 2-amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride; AD; Alzheimer's disease; Aβ; amyloi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; APP; amyloid precursor protein; BACE1; beta-site APP-cleaving enzyme 1; CuBD; copper binding domain; ICD; intracellular domain; PCa; prostate cancer; sAPPα; soluble APP alpha; sAPPβ; soluble APP beta; SDS-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewAlzheimer's and ABC transporters - new opportunities for diagnostics and treatment

Keywords: AD; Alzheimer's disease; Aβ; amyloid-beta; ABC; ATP binding cassette; BBB; blood-brain barrier; BPND; non-displaceable binding potential; CAA; cerebral amyloid angiopathy; CSF; cerebrospinal fluid; CP; choroid plexus; DLB; dementia with Lewy bodies;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of mitochondrial fission attenuates Aβ-induced microglia apoptosis

Keywords: AD; Alzheimer's disease; Aβ; β-amyloid protein; BALB; Bagg albino; CytC; cytochrome c; DMEM; Dulbecco's modified eagle medium; Drp1; dynamin-related protein 1; FBS; fetal bovine serum; GTP; Guanosine triphosphate; HD; Huntington's disease; Mdivi-1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Implications of heparan sulfate and heparanase in neuroinflammation

Keywords: HS; heparan sulfate; HSPG; heparan sulfate proteoglycan; SDC; syndecan; GPC; glypican; -OST; -O-sulfotransferase; NDST; N-deacetylase-N-sulfotransferase; FGF; fibroblast growth factor; CNS; central nervous system; BBB; Blood Brain Barrier; ECM; extracel

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Lixisenatide rescues spatial memory and synaptic plasticity from amyloid β protein-induced impairments in rats

Keywords: AD; Alzheimer's disease; Aβ; amyloid β; ANOVA; analysis of variance; BBB; blood-brain barrier; DPPIV; DPPIV dipeptidyl peptidase IV; fEPSPs; Field excitatory postsynaptic potentials; GLP-1; glucagon-like peptide-1; GLP-1R; GLP-1 receptor; GSK3β; gl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Novel presenilin mutations within Moroccan patients with Early-Onset Alzheimer's Disease

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; beta-amyloid; EOAD; Early-Onset Alzheimer's Disease; FAD; familial Alzheimer's disease; MRI; Magnetic Resonance Imaging; MMSE; Mini-Mental State Examination; PS1; presenilin 1; PS2; prese

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice

Keywords: AD; Alzheimer's disease; AICD; amyloid precursor protein intracellular domain; ANOVA; analysis of variance; APP; amyloid precursor protein; Aβ; amyloid-β; βFGF; fibroblast growth factor; BrdU; 5-bromo-2-deoxyuridine; DMEM; Dulbecco's modified Eagle m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid precursor protein; DMEM; Dulbecco's-Modified Essential Medium; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; LDH; lactate dehydrogenase; l-NBP; l-3-n-butylphthalide; 3-MA; 3-m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Exogenous amyloidogenic proteins function as seeds in amyloid β-protein aggregation

Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; Act; actin; αS; α-synuclein; Cas; casein; EM; electron microscopy; Fibro; fibroin; fAβ; Aβ fibrils; fAct; Act fibrils; fCas; casein fibrils; fFibro; fibroin fibrils; fIAPP; IAPP fibrils; fSer; sericin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Purification of pre-miR-29 by arginine-affinity chromatography

Keywords: miRNA; microRNA; RNA; ribonucleic acid; mRNA; messenger RNA; RISC; RNA-induced silencing complex; AD; Alzheimer's disease; Aβ; β-amyloid; APP; β-amyloid precursor protein; BACE1; β-site APP-cleaving enzyme 1; SPE; silica-based solid-phase extraction;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

SEVI, the semen enhancer of HIV infection along with fragments from its central region, form amyloid fibrils that are toxic to neuronal cells

Keywords: Aβ; Amyloid β; AIDS; Acquired Immunodeficiency Syndrome; COCA-2; Epithelial colon carcinoma cells; HIV; Human Immunodeficiency Virus; MTT; 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide; PAP; Prostatic acid phosphatase; PC 12; Pheochromocyt

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Protective effects of perindopril on d-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampus of mice

Keywords: Aβ; beta-amyloid protein; AD; Alzheimer's disease; AlCl3; aluminium trichloride; d-gal; d-galactose; GSH-Px; glutathione peroxidase; MDA; malondialdehyde; ROS; reactive oxygen species; SOD; superoxide dismutase; Perindopril; d-Galactose; Aluminum trichlo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Research reportRutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation

Keywords: Rutin; Alzheimer's disease; β-Amyloid; Oligomer; Oxidative stress; Neuroinflammation; AD; Alzheimer's disease; Aβ; β-amyloid; MWM; Morris water maze; ROS; reactive oxygen species; GSH; glutathione; GSSG; glutathione disulfide; MDA; malondialdehyde; SOD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Widespread genome transcription: New possibilities for RNA therapies

Keywords: Aβ; amyloid beta; AGO; argonaute; AON; antisense oligonucleotide; AS RNA; antisense RNA; ATL; adult T-cell leukemia; EBOV; Ebola virus; eRNA; enhancer RNA; ES; embryonic stem; HBZ; HTLV-1 basic leucine zipper factor; HTLV-1; human T-cell leukemia virus t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; ATP; adenosine triphosphate; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; AMP; adenos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Localization of amyloid beta (Aβ1-42) protofibrils in membrane lateral compartments: Effect of cholesterol and 7-Ketocholesterol

Keywords: Cholesterol; 7-Ketocholesterol; Amyloid beta localization; Membrane lateral compartments; Membrane fluidity; 7keto; 7-Ketocholesterol; Aβ; amyloid beta; AD; Alzheimer's disease; Fig; Figure; GM1; monosialotetrahexosylganglioside; GP; generalized polari

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of TRPV4 channels in Aβ40-induced hippocampal cell death and astrocytic Ca2+ signalling

Keywords: AA; arachidonic acid; Aβ; amyloid β peptide; BSO; buthionine sulfoximine; GFAP; glial fibrillary acidic protein; GSH; reduced glutathione; MAFP; methyl arachidonyl fluorophosphonate; MAP2; microtubule associated protein-2; PI; propidium iodide; PLA2; ph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Amyloid β binds procaspase-9 to inhibit assembly of Apaf-1 apoptosome and intrinsic apoptosis pathway

Keywords: Aβ; Amyloid-β; ABAD; alcohol dehydrogenase; ACE; cells treated with 20 μM Aβ42; AD; Alzheimer's disease; C9; caspase-9; Cyto c; cytochrome c; ΔC; caspase-9 lacking the prodomain; HCE; extracts prepared from untreated healthy HeLa cells; MTT; 3-(4, 5

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; BBB; blood-brain barrier; BSA; bovine serum albumin; GSK-3β; glycogen synthase kinase-3β; GST; glutathione S-transferase; ICV; intracerebroventricularly; NFTs; neurofibrillary tangles; Nrf2; nuclear factor-E

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Detection and quantification of plasma amyloid-β by selected reaction monitoring mass spectrometry

Keywords: Aβ; amyloid-β; SRM; selected reaction monitoring; RPLC; reversed-phase liquid chromatography; LOQ; limit of quantification; CSF; cerebrospinal fluid; AD; Alzheimer's disease; APP; amyloid precursor protein; ApoE; apolipoprotein E; ApoJ; apolipoprotein J

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Differential role of APP and APLPs for neuromuscular synaptic morphology and function

Keywords: AD; Alzheimer's disease; Aβ; amyloid β-peptide; APP; amyloid precursor protein; APLPs; amyloid precursor-like proteins; KO; knock-out; DKO; double knockout; NMJ; neuromuscular junction; CNS; central nervous system; PNS; peripheral nervous system; KPI; K

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Inactivation of brain Cofilin-1 by age, Alzheimer's disease and γ-secretase

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; APP/PS1; APPKM670/671NL/PS1L166P transgenic mice; APPKO; amyloid precursor protein knockout mice; Aβ; Amyloid-β peptides; Cofilin1; Cofilin isoform 1; CpdE; Compound E; DIV; days in vitro; DMSO; d

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Featured ArticleAβ and cognitive change: Examining the preclinical and prodromal stages of Alzheimer's disease

Keywords: Aβ; Cognitive decline; Preclinical AD; Prodromal AD; Neuropsychology;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease

Keywords: Aβ; Alzheimer's disease; Pore formation; Membrane disruption; Aβ toxicity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroprotective effect of purple rice extract and its constituent against amyloid beta-induced neuronal cell death in SK-N-SH cells

Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; APP; amyloid precursor protein; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CAT; catalase; DNA; deoxyribonucleic acid; DPPH; 2,2-diphenyl-1-picrylhydrazyl; EDTA; ethylenediaminetetra acetic acid;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Excessive hydrogen peroxide enhances the attachment of amyloid β1-42 in the lens epithelium of UPL rats, a hereditary model for cataracts

Keywords: ADAM10; A disintegrin and metalloprotease domain protease 10; Aβ; amyloid β; APP; amyloid precursor protein; BACE1β; site APP cleaving enzyme; Ca2+; calcium ion; DDC; diethyldithiocarbamate; DMSO; dimethyl sulfoxide; DSF; disulfiram; GSH; glutathione;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Interleukin-1β mediated amyloid plaque clearance is independent of CCR2 signaling in the APP/PS1 mouse model of Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; APP; amyloid precursor protein; APP/PS1; APPswe/PS1dE9; IL-1β; interleukin-1 beta; CCR2; chemokine (C-C motif) receptor 2; BMD; bone marrow-derived; eGFP; enhanced green fluorescent protein; Iba1; ionized calci

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Research ReportImpaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration

Keywords: Aβ; amyloid beta; ACh; acetylcholine; AD; Alzheimer's disease; APP; amyloid precursor protein; BFCD; basal forebrain cholinergic degeneration; ChAT; choline acetyltransferase; HPLC; high performance liquid chromatography; icv; intracerebroventricular;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Neural HO-1/sterol interactions in vivo: Implications for Alzheimer's disease

Keywords: 3xTg-AD; triple transgenic AD mouse; 4β-OH; 4β-hydroxycholesterol; 7α-OH; 7α-hydroxycholesterol; 7β-OH; 7β-hydroxycholesterol; 7keto-CH; 7-ketocholesterol; 24-OH; 24-hydroxycholesterol; Aβ; β-amyloid; AD; Alzheimer-disease; APP; amyloid precursor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice

Keywords: AD; Alzheimer's disease; apoE; apoliporpotein E; apoE TR mice; human apoE3- and apoE4-targeted replacement mice; APP; amyloid precursor protein; Aβ; amyloid beta peptide; BDNF; Brain-derived Neurotrophic Factor; DDCt; Delta-Delta Ct; EDTA; ethylenedi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Aβ-AGE aggravates cognitive deficit in rats via RAGE pathway

Keywords: Aβ; β-amyloid; Aβ-AGE; glycated Aβ; AD; Alzheimer's disease; AGEs; advanced glycation end-products; AP; anterior to posterior; APP; amyloid precursor protein; DV; dorsal to ventral; EDTA; ethylenediaminetetraacetic acid; EPSP; excitatory postsynapti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease

Keywords: Aβ; APP; tau; Tangles; β Blockers;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

N-truncation and pyroglutaminylation enhances the opsonizing capacity of Aβ-peptides and facilitates phagocytosis by macrophages and microglia

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; APP; amyloid precursor protein; BSA; bovine serum albumin; CNS; central nervous system; DAMP; damage-associated molecular pattern; DAPI; 4′,6-diamidino-2-phenylindole; E. coli; Escherichia coli; EDTA; ethylene

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; ADAM; a disintegrin and metalloproteinase; APP; amyloid precursor protein; BACE1; β-site APP-cleaving enzyme-1; BCA; bicinchoninic acid; BSA; bovine serum albumin; CA; carnosic acid; CHAPS; 3-[(3-Cholamidopropyl)

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Memantine improves spatial learning and memory impairments by regulating NGF signaling in APP/PS1 transgenic mice

Keywords: Aβ; β-amyloid; AD; Alzheimer's diseases; APP; amyloid precursor protein; BDNF; brain-derived neurotrophic factor; c-Raf; proto-oncogene serine/threonine-protein kinase, Raf1; CREB; cAMP-response element binding protein; DAB; 3′-diaminobenzidine; ERK

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Frealix: Model-based refinement of helical filament structures from electron micrographs

Keywords: WLC; worm-like chain; Aβ; amyloid beta; Amyloid; Structure; Cryo-EM; Curvature; Filament; Helical;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; Akt; protein kinase B; APP; amyloid precursor protein; BACE1; β-site APP-cleaving enzyme 1; BDNF; brain-derived neurotrophic factor; CGI-S; Clinical Global Impression-Severity scale; CREB; cAMP-response element

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Screening and identification of neuroprotective compounds relevant to Alzheimer׳s disease from medicinal plants of S. Tomé e Príncipe

Keywords: Aβ; amyloid beta peptide; AD; Alzheimer׳s disease; APP; amyloid precursor protein; ATP; adenosine triphosphate; BBB; blood-brain barrier; CLogP; lipophilicity; CNS; Central nervous system; DMEM; Dulbecco׳s modified Eagle׳s medium; ESI; Electrospray

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D

Keywords: Phosphodiesterase inhibitors; GEBR-7b; APP/PS1; Cognition; BDNF; CREB; Aβ; amyloid-β; AD; Alzheimer's disease; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-bindin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation

Keywords: AD; Alzheimer disease; Aβ; β-amyloid; APP; amyloid precursor protein; ASMase; acid sphingomyelinase; BACE; β-secretase β-site amyloid cleaving enzyme; BBB; blood-brain barrier; BCA; bicinchoninic acid; BHT; butylated hydroxytoluene; BSO; buthionine

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease

Keywords: Aβ; β-amyloid peptide; AD; Alzheimer disease; ETC; electron transport chain; DCFDA; 2,7-dichorofluorescein diacetate; mtDNA; mitochondrial DNA; APP; amyloid precursor protein; ROS; reactive oxygen species; MitoQ; mitoquinone mesylate, 10-(4,5-dimethoxy-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

Keywords: AD; Alzheimer's disease; mtDNA; Mitochondrial DNA; DLP1; Dynamin-like protein; Mfn2; Mitofusin 2; ERK; Extracellular signal-regulated kinase; Aβ; Amyloid beta peptide; CcO; Cytochrome c oxidase; ROS; Reactive oxygen species; PD; Parkinson disease; HD; Hu

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Aβ induces its own prion protein N-terminal fragment (PrPN1)-mediated neutralization in amorphous aggregates

Keywords: Alzheimer; α-Cleavage; PrPN1; Aβ; Amorphous aggregates; Diffuse plaques; Prion; Neuroprotection; Fibrillization;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه