دانلود مقالات ISI درباره Aβ + ترجمه فارسی

Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity

Keywords: AD; Alzheimer disease; FAD; familial AD; Aβ; amyloid-β peptide; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme 1; PDMP; dl-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; DMAPP; (1S,2R-d-erythro-2-N-myristoylamino)-1-phenyl-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Live imaging reveals a new role for the sigma-1 (σ1) receptor in allowing microglia to leave brain injuries

Keywords: Aβ; amyloid-β; IL; interleukin; TNF; tumor necrosis factor; σ Receptor; Fluorescence microscopy; Microglia; Optical imaging;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Curcumin inhibits Aβ-induced microglial inflammatory responses in vitro: Involvement of ERK1/2 and p38 signaling pathways

Keywords: Microglia; Curcumin; Aβ; Inflammation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Hippocampal DHCR24 down regulation in a rat model of streptozotocin-induced cognitive decline

Keywords: AD; Alzheimer's disease; Aβ; amyloid β; DHCR24; 24-dehydrocholesterol reductase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; ICV-STZ; intracerebroventricular-streptozotocin; IGF-1; insulin-like growth factor 1; MWM; Morris water maze; RT-PC; re

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Keywords: ACO1; acotinase 1; AD; Alzheimer's disease; ANCOVA; univariate analysis of co-variance; APP; amyloid-beta precursor protein; Aβ; amyloid-beta; CDR; Clinical Dementia Rating; Cp; ceruloplasmin; CPO; Cp oxidase activity; eQTLs; expression quantitative trai

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Stabilization of intracellular trafficking and metabolism of amyloid β-protein precursor and Alcadein β by apolipoprotein E

Keywords: AD; Alzheimer's disease; Alcs; Alcadein family proteins; Alcα; Alcadein α; Alcβ; Alcadein β; Alcγ; Alcadein γ; APP; amyloid β-protein precursor; Aβ; β-amyloid; p3-Alc; small peptide generated by α-and γ-site cleavages of Alc; sAlc; amino-term

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 mice

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β peptide; ANOVA; one-way analysis of variance; APP; amyloid-β precursor protein; BCA; bicinchoninic acid; BrdU; 5-bromo-2-deoxyuridine; DG; dentate gyrus; ELISA; enzyme-linked immunosorbent assay; NeuN; neuron-sp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The effects of ginsenosides to amyloid fibril formation by RCMκ-casein

Keywords: Ginsenosides; Amyloid fibrils; κ-Casein; ThT assay; TEM; AD; Alzheimer's disease; Aβ; Amyloid β; A.U.; arbitrary units; CA; corpora amylacea; PD; Parkinson's disease; RCMκ-CN; reduced and carboxymethylated κ-casein; TEM; transmission electron microsc

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A facile method for expression and purification of 15N isotope-labeled human Alzheimer's β-amyloid peptides from E. coli for NMR-based structural analysis

Keywords: AD; Alzheimer's disease; Aβ; Alzheimer's β-amyloid peptide; IDP; intrinsically disordered peptide; IFABP; intestinal fatty acid binding protein; LB; lysogeny broth; DTT; dithiothreitol; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The kynurenine pathway and neurodegenerative disease

Keywords: 3-HANA; 3-hydroxyanthranilic acid; 3-HAO; hydroxyanthranilate 3,4-dioxygenase; 3-HK; 3-hydroxykynurenine; α7nACh; α7-nicotinic acetylcholine; Aβ; β-amyloid peptide; ACMS; 2-amino-3-carboxymuconic 6-semialdehyde; AD; Alzheimer's disease; aSyn; α-synuc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations

Keywords: P-glycoprotein; Aβ; Blood-brain barrier; Aging; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid

Keywords: Aβ; β-amyloid; AD; Alzheimer's Disease; AICD; APP Intracellular Domain; APP; Amyloid Precursor Protein; ARG1; Arginase 1; CHF5074; 1-(3′,4′-dichloro-2-fluoro[1,1′-biphenyl]-4-yl)-cyclopropanecarboxylic acid; FIZZ1; Found in Inflammatory Zone; GS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloid-β precursor protein: Multiple fragments, numerous transport routes and mechanisms

Keywords: APP; Amyloid-β Precursor Protein; AD; Alzheimer׳s disease; Aβ; Amyloid-β; ER; endoplasmic reticulum; ERGIC; ER-Golgi Intermediate Compartment; TGN; trans-Golgi network; AICD; APP Intracellular Domain; PTB; phosphotyrosine binding; JIP-1; JNK-interacti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ShcC proteins: Brain aging and beyond

Keywords: ShcC adaptor proteins; Signaling; Aging; Brain ischemia; Brain tumors; Immunity; Aβ; beta-amyloid; AD; Alzheimer's disease; Akt; protein kinase B (PKB); ALK; anaplastic lymphoma kinase (receptor tyrosine kinase); APP; alpha-amyloid precursor protein; ARD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice

Keywords: Aβ; amyloid β-peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; APP/PS1 mice; mice with APPswe/PS1ΔE9 mutations; DNMT; DNA methyltransferase; HCY; homocysteine; IOD; integrated optical density; OD; optical density; ORF; open reading f

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Acetylation and phosphorylation of STAT3 are involved in the responsiveness of microglia to beta amyloid

Keywords: STAT3; 14-3-3epsilon; Alzheimer's disease; Amyloid beta peptides; Microglia; ac-STAT3(K685); acetylated form of STAT3 on Lys685 residue; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid beta peptides; CCL5; chemokine (C-C motif) lig

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one

Keywords: ASK1; apoptosis signal-regulating kinase 1; MAPK; mitogen-activated protein kinase; ER; endoplasmic reticulum; TNF-α; tumor necrosis factor-alpha; AIP-1; ASK1-interacting protein 1; VEGF; vascular endothelial growth factor; Aβ; amyloid beta; CK2; protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewNeuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy

Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; ADAPT; Alzheimer's Disease Anti-inflammatory Prevention Trial; APP; amyloid precursor protein; ARG1; arginase 1; CAA; cerebral amyloid angiopathy; CSF; cerebrospinal fluid; ICAM1; intracellular adhesion mole

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Microvesicles in the brain: Biomarker, messenger or mediator?

Keywords: ABCA1; ATP-binding cassette transporter A1; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-beta peptide; CM; cerebral malaria; CNS; central nervous system; CSF; cerebrospinal fluid; EAE; experimental autoimmune encephalomyelitis; EM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo

Keywords: AD; Alzheimer׳s disease; Aβ; amyloid-beta; ABC; avidin-biotin peroxidase complex; Bcl-2; B-cell lymphoma 2; Bax; Bcl-2-associated X; DAB; 3,3-diaminobenzidine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; GSK-3β; glycogen syntha

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

LC3 overexpression reduces Aβ neurotoxicity through increasing α7nAchR expression and autophagic activity in neurons and mice

Keywords: α7nAChR; Aβ; Apoptosis; Autophagy; LC3;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells

Keywords: 5-Aza; 5-Aza-2′-deoxycytidine; α-CTF; α-C-terminal fragment; β-CTF; β-C-terminal fragment; AD; Alzheimer's disease; APP; amyloid precursor protein; ASBI; APP-selective BACE1 inhibitor; Aβ; β-amyloid; BACE1; β-site amyloid precursor protein-clea

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportPaeoniflorin attenuates Aβ1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-κB- and VEGF/Flt-1 signaling pathways

Keywords: Aβ; beta-amyloid; AD; Alzheimer׳s disease; CNS; central nervous system; PF; paeoniflorin; TNF-α; tumor necrosis factor α; IL-1β; interleukin 1β; IL-6; interleukin 6; NF-κB p65; nuclear factor kappa B subunit p65; IκBα; NF-κB inhibitor alpha; CXC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Accumulation and age-related elevation of amyloid-β within basal forebrain cholinergic neurons in the rhesus monkey

Keywords: Aβ; amyloid-β; Aβ1-40; 1-40 amino acid isoform of Aβ; Aβ1-42; 1-42 amino acid isoform of Aβ; AD; Alzheimer's disease; APP; amyloid precursor protein; BFCN; basal forebrain cholinergic neurons; Ca2 +; calcium; Ch4; cholinergic cell group 4;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Treadmill exercise enhances synaptic plasticity, but does not alter β-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; β-amyloid; DG; dentate gyrus; ELISA; enzyme-linked immune sorbent assay; f-EPSP; field-excitatory postsynaptic potential; HFS; high-frequency stimulation; IHC; immunohistochemical; LTD; long

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer's disease in vitro and in vivo

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; ARE; antioxidant response element; Aβ; amyloid-beta; BACE; β-secretase; EDTA; ethylenediaminetetraacetic acid; ERK; Extracellular signal-regulated kinase; GSK3β; glycogen synthase kinase-3beta;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer's disease

Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; ANOVA; analysis of variance; APP; amyloid precursor protein; CSF; cerebrospinal fluid; DLBD; Diffuse Lewy Body Disease; ISF; interstitial fluid; PS1; Presenilin1; REM; rapid eye movement; SWS; slow wave sleep;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model

Keywords: Alzheimer's disease; Geniposide; APP/PS1 transgenic mice; Amyloid-β; Receptor for advanced glycation end products; AD; Alzheimer's disease; APP/PS1 mice; mPrP-APPswe/PS1dE9 AD transgenic mice; Aβ; Amyloid-beta peptide; BACE1; β-site APP cleaving enzyme

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Asymmetric dimethylarginine exacerbates Aβ-induced toxicity and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease

Keywords: AD; Alzheimer disease; ADMA; asymmetric dimethylarginine; APP; β-amyloid precursor protein; APPsw; Swedish mutant form of human β-amyloid precursor protein; Aβ; β-amyloid; CSF; cerebrospinal fluid; DDAH; dimethylarginine dimethylaminohydrolase; ERK; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Ischemic conditions and β-secretase activation: The impact of membrane cholesterol enrichment as triggering factor in rat brain endothelial cells

Keywords: CNS; central nervous system; AD; Alzheimer's disease; RBE4; rat brain endothelial cell line; OGD; oxygen and glucose deprivation; ogR; oxygen and glucose Restoration; BACE1; amyloid precursor protein (APP) β-secretase; PSEN1; presenilin-1; Aβ; amyloid p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR

Keywords: TLR2; SIGIRR; TIR8; Aβ; Microglia; LTP; Hippocampus; PPARγ; PI3 kinase; Akt;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells

Keywords: Aβ; β-amyloid; AGC1; aspartate/glutamate carrier isoform 1; APP; amyloid precursor protein; BAPTA-AM; 1,2-bis(2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester); ChIP; chromatin immunoprecipitation; P-CREB; phospho-cAMP-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Dietary (−)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing

Keywords: Flavanol; Flavonoid; Alzheimer's disease; TASTPM; BACE1; Amyloid pathology; Aβ; Dietary polyphenolic; Dementia; APP processing; Catechin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography

Keywords: Alzheimer's disease; β-Amyloid plaques; Benzyloxybenzenes; F-18 tracer; PET imaging; AD; Alzheimer's disease; Aβ; β-amyloid; PET; positron emission tomography; PIB; 2-(40-(methylaminophenyl)-6-hydroxybenzothiazole; GE-067; 2-(3-fluoro-4-(methylamino)ph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Emerging roles of the γ-secretase-notch axis in inflammation

Keywords: Inflammation; Notch; γ-Secretase; Inflammatory diseases; Stroke; Aβ; amyloid-β; AD; Alzheimer's disease; AICD; APP intracellular domain; ALPS; autoimmune lymphoproliferative syndrome; Aph-1; anterior pharynx-defective 1; ApoE; apolipoprotein E; APP; am

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-HSV1 activity of brown algal polysaccharides and possible relevance to the treatment of Alzheimer's disease

Keywords: AD; Alzheimer's disease; ACV; acyclovir; HSV1; herpes simplex virus type 1; Aβ; β-amyloid; P-tau; AD-like tau; APOE-ɛ4; apolipoprotein E, type 4 allele; PRA; plaque reduction assay; ICC; immunocytochemistry; MOI; multiplicity of infection; Alzheimer's

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Reconstituted mother tinctures of Gelsemium sempervirens L. improve memory and cognitive impairment in mice scopolamine-induced dementia model

Keywords: AD; Alzheimer׳s disease; Aβ; amyloid β; AChE; acetylcholinesterase; ANOVA; analysis of variance; ANSM; Agence Nationale de Sécurité des Médicaments (French); APP; amyloid precursor protein; b-APP; b-amyloid precursor protein; ATCI; acetylthiocholine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular chaperones and neuronal proteostasis

Keywords: 17-AAG; 17-allylamino-17-demethoxygeldanamycin; 17-DMAG; 17-dimethylamino-ethylamino-17-demethoxygeldanamycin; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ARSACS; autosomal recessive spastic ataxia of Charlevoix-Saguena

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Oleic acid ameliorates Aβ-induced inflammation by downregulation of COX-2 and iNOS via NFκB signaling pathway

Keywords: AD; Alzheimer's disease; Aβ; amyloid β peptide; APP; amyloid peptide precursor; β-secretase; BACE1; ROS; reactive oxygen species; COX-2; cyclooxygenase; iNOS; inducible nitric oxide synthase; NF-κB; nuclear factor-κB; MAPK; mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Long-term treatment with Ginkgo biloba extract EGb 761 improves symptoms and pathology in a transgenic mouse model of Alzheimer's disease

Keywords: Alzheimer's disease; Aβ; Autophagy; Inflammation; Microglia; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The storm before the quiet: neuronal hyperactivity and Aβ in the presymptomatic stages of Alzheimer's disease

Keywords: Alzheimer's disease; Aβ; Neuronal hyperactivity; Synaptotoxicity; Disease progression;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure

Keywords: Toxin exposure; Alzheimer's disease; Inflammation; NLRP3 inflammasome; Paraquat; Mitochondria; Oxidative stress; Aβ;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin

Keywords: Amyloid-beta; Neprilysin; Intra-vitreal injection; C57BL/6J mouse; 5XFAD mouse; Electroretinogram; Aβ; amyloid-beta; NEP; neprilysin; sNEP; soluble catalytic domain of neprilysin; PA; phosphoramidon; ERG; electroretinogram; PBS; phosphate-buffered saline

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportEstrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1

Keywords: AD; Alzheimer׳s Disease; Aβ; amyloid β; ERβ; estrogen receptor β; Drp1; dynamine-related protein 1; PKA/AKAP1; protein kinase A/A kinase anchoring protein 1; DPN; Diarylpropionitrile (2,3-bis(4-Hydroxyphenyl)-propionitrile); Estrogen receptor β; Alz

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Lysophosphatidylcholine increases the neurotoxicity of Alzheimer's amyloid β1-42 peptide: Role of oligomer formation

Keywords: Aβ; amyloid β; AD; Alzheimer's disease; DHE; dihydroethidium; DMEM; Dulbecco's modified eagle medium; EC; endothelial cell; FBS; fetal bovine serum; IgG; immunoglobulin G; LDH; lactate dehydrogenase; LPC; lysophosphatidylcholine; MTT; Dimethyl thiaz

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer's disease

Keywords: AD; Alzheimer's disease; ANOVA; analysis of variance; Aβ; amyloid-β; BBB; blood-brain barrier; EDTA; ethylenediaminetetraacetic acid; ET; endothelin; MAPK; mitogen-activated protein kinase; MWM; Morris water maze; NGF; nerve growth factor; PBS; phos

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective effect of astaxanthin against glutamate-induced cytotoxicity in HT22 cells: Involvement of the Akt/GSK-3β pathway

Keywords: AD; Alzheimer's disease; AIF; apoptosis-inducing factor; ARE; antioxidant-responsive element; ATX; astaxanthin; Aβ; β-amyloid; Cyto-c; cytochrome-c; DCFH-DA; dichlorofluorescein dilacerate; FBS; Fetal bovine serum; GSK-3β; glycogen synthase kinase-3Î

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol

Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; IP; immunoprecipitation; SEC; size exclusion chromatography; AβM; Aβ monomers; AβD; LDS-stable Aβ dimers; Chiro; chiro-inositol; Scyllo; scyllo-inositol; ICC; immunocytochemistry; IHC; immunohistochemi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

Keywords: N-terminally truncated; Aβ; Alzheimer's disease; Neurons; Astrocytes; Microglia; Intracellular; Extracellular; BACE; Secretase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth

Keywords: Alzheimer's disease; β-amyloid; Disaggregation; Neurite outgrowth and neurodegeneration; AD; Alzheimer's disease; Aβ; β-amyloid; fAβ; Aβ fibrils; NGF; nerve growth factor; AChE; acetylcholinesterase; GAP43; growth-associated protein 43; MAPK; mitogen

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه