
Premature ageing of the immune system underlies immunodeficiency in ataxia telangiectasia
Keywords: ATM, ataxia telangiectasia mutated gene product; A-T, ataxia telangiectasia; BCR B, cell receptor; CHK2, cell cycle checkpoint kinase 2; CREB, cAMP response element-binding protein; IGF1, insulin-like growth factor 1; KAP-1, KRAB associated protein; NBS1,