Cadmium exposure exerts neurotoxic effects in peacock blennies Salaria pavo
Keywords: حمل کننده ABC; CdCl2; Salaria pavo; mRNA expression; Histology; ABC transporters; AChE;
مقالات ISI حمل کننده ABC (ترجمه نشده)
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4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer
Keywords: حمل کننده ABC; ABC transporters; ATP-binding cassette transporters; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; AOR; alkenal/one oxidoreductase; AP-1; activator Protein-1; AR; aldose reductase; ARE/EpRE;
Research articleProteomic comparison of Chelidonium majus L. latex in different phases of plant development
Keywords: حمل کننده ABC; Chemometrics; Defense-related proteins; Greater Celandine; Label-free protein quantification; Major latex protein; Milky sap; 2-DE; two-dimensional electrophoresis; ABC transporters; ATP-binding cassette transporters; CDS; coding sequences; LRR; leucine-r
A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies
Keywords: حمل کننده ABC; MDCK cells; ABC transporters; efflux pumps; P-glycoprotein; permeability; membrane transporter; drug transport; genomics; proteomics; multidrug resistance transporters;
Specific stabilization of CFTR by phosphatidylserine
Keywords: حمل کننده ABC; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; EGFP; enhanced green fluorescent protein; NBD; nucleotide binding domain; PI; phosphatidylinositol; POPC; 1-palmitoyl-2-oleoyl-phosphatidylcholine; POPE; 1-palmitoyl-2-oleoyl-
Characterization of cancer stem cell drug resistance in the human colorectal cancer cell lines HCT116 and SW480
Keywords: حمل کننده ABC; Colonosphere; Cancer stem cell markers; Aldehyde dehydrogenase; ABC transporters;
Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins
Keywords: حمل کننده ABC; ABC transporters; P-glycoprotein (P-gp); Cancer; Chemotherapeutic drugs; Multidrug resistance; 7q21 amplicon; Sorcin;
Rosuvastatin Pharmacokinetics in Asian and White Subjects Wild Type for Both OATP1B1 and BCRP Under Control and Inhibited Conditions
Keywords: حمل کننده ABC; clinical pharmacokinetics; drug interaction; race; organic anion-transporting polypeptide transporters; ABC transporters; efflux pumps; hepatic transport; intestinal absorption;
Mdr65 decreases toxicity of multiple insecticides in Drosophila melanogaster
Keywords: حمل کننده ABC; ABC transporters; Drosophila melanogaster; Mdr65; Insecticide toxicity; RNAi;
Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP
Keywords: حمل کننده ABC; drug interactions; intestinal absorption; pharmacokinetics; pharmacogenomics; organic anion-transporting polypeptide transporters; ABC transporters;
Circadian Clock Is Involved in Regulation of Hepatobiliary Transport Mediated by Multidrug Resistance-Associated Protein 2
Keywords: حمل کننده ABC; ABC transporters; P-glycoprotein; multidrug resistance-associated proteins; pharmacokinetics; biliary excretion; ABC; ATP-binding cassette; Bcrp; breast cancer resistance protein; BMAL1; brain and muscle arnt-like protein-1; CLOCK; circadian locomotor out
R- and S-Warfarin Were Transported by Breast Cancer Resistance Protein: From In Vitro to Pharmacokinetic-Pharmacodynamic Studies
Keywords: حمل کننده ABC; ABC transporters; drug transport; mass spectrometry; preclinical pharmacokinetics; pharmacokinetics/pharmacodynamics; INR; international normalized ratio; BCRP; breast cancer resistance protein; ABCG2; ATP-binding cassette transporter G2; CYP450; cytochro
A Critical View on In Vitro Analysis of P-glycoprotein (P-gp) Transport Kinetics
Keywords: حمل کننده ABC; drug transport; ABC transporters; P-glycoprotein; Michaelis-Menten kinetics; drug interactions; ADME; in vitro models;
Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites
Keywords: حمل کننده ABC; ABC transporters; transporters; skin; P-glycoprotein; tissue partition; ABCB1; ATP binding cassette subfamily B member 1; ABCG2; ATP binding cassette subfamily G member 2; BCRP; breast cancer resistance protein; CRC; colorectal cancer; CYP3A4; cytochrome
Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
Keywords: حمل کننده ABC; MDCK cells; CRISPR-Cas9; ABC transporters; efflux pumps; P-glycoprotein; permeability; membrane transporter; drug transport; genomics; proteomics;
Breast Cancer Resistance Protein Abundance, but Not mRNA Expression, Correlates With Estrone-3-Sulfate Transport in Caco-2
Keywords: حمل کننده ABC; Caco-2 cells; proteomics; liquid chromatography; mass spectrometry; intestinal absorption; efflux pumps; ABC transporters; ABC; ATP-dependent binding cassette; BCRP; breast cancer resistance protein; BSA; bovine serum albumin; E-3-S; estrone-3-sulfate; HB
Role of the lysophosphatidylinositol/GPR55 axis in cancer
Keywords: حمل کننده ABC; LPI; G protein-coupled receptor 55; Cancer; ABC transporters; Cannabidiol;
Usefulness of A Model-Based Approach for Estimating In Vitro P-Glycoprotein Inhibition Potency in a Transcellular Transport Assay
Keywords: حمل کننده ABC; ABC transporters; Caco-2 cells; drug interactions; efflux pumps; inhibition; mathematical models; membrane transport/transporters; P-glycoprotein; pharmacokinetics; transporters;
Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [18F]Ciprofloxacin, a Positron Emission Tomography Study in Mice
Keywords: حمل کننده ABC; PET; drug interactions; hepatic transport; ABC transporters; multidrug resistance-associated proteins; organic anion-transporting polypeptide transporters; hepatobiliary disposition;
Inhibitory potential of tuberculosis drugs on ATP-binding cassette drug transporters
Keywords: حمل کننده ABC; Tuberculosis; Drug-drug interactions; ABC transporters; Membrane vesicles; Protein overexpression; Vesicular transport assay;
Toxicological effects of particulate matter (PM2.5) on rats: Bioaccumulation, antioxidant alterations, lipid damage, and ABC transporter activity
Keywords: حمل کننده ABC; Antioxidant capacity; Bioaccumulation; Heart; ABC transporters; Oxidative stress; Particulate matter;
Danio rerio embryos on Prozac – Effects on the detoxification mechanism and embryo development
Keywords: حمل کننده ABC; Fluoxetine; Zebrafish embryos; ABC transporters; Phase I and II; Antioxidant enzymes; Nuclear receptors
Genetic features of livestock-associated Staphylococcus aureus ST9 isolates from Chinese pigs that carry the lsa(E) gene for quinupristin/dalfopristin resistance
Keywords: حمل کننده ABC; Staphylococcus aureus; Quinupristin/dalfopristin; Resistance; Livestock-associated; ST9; ABC transporters;
Know your ABCs: Characterization and gene expression dynamics of ABC transporters in the polyphagous herbivore Helicoverpa armigera
Keywords: حمل کننده ABC; ABC transporters; Detoxification; Generalist; Helicoverpa armigera; Herbivore; TranscriptomeABC, ATP-binding cassette (transporter); MT, Malpighian tubules; G, gut; RB, rest body; NBD, nucleotide binding domain; Ha, Helicoverpa armigera; Hvir, Heliothis v
Crystal structure analysis in Zn2+-bound state and biophysical characterization of CLas-ZnuA2
Keywords: حمل کننده ABC; Candidatus Liberibacter asiaticus; ABC transporters; Metal binding protein; Crystal structure; Surface plasmon resonance; Circular dichroism;
Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer
Keywords: حمل کننده ABC; intestinal absorption; membrane conductance and resistance; paracellular transport; permeability; tight junction; transcellular transport; ABC transporters; cell culture; intestinal epithelia;
Bioinformatic survey of ABC transporters in dermatophytes
Keywords: حمل کننده ABC; ABC; ATP binding cassette; NBD; nucleotide binding domain; TMD; transmembrane domain; Dermatophytes; ABC transporters; Drug resistance; Phylogenetics;
2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2
Keywords: حمل کننده ABC; ABC transporters; ABCC2 inhibitors; Indolylmethylenebenzofuranone; Aurones; Drug interactionsABCC2, second member of the C subfamily of the ABC pumps; DDI, drug-drug interactions; P-gp, P-glycoprotein; MRP, multidrug resistance protein; BCRP, breast cance
The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
Keywords: حمل کننده ABC; proteomics; caco-2 cells; permeability; transporters; ABC transporters; solute transporters; epithelial delivery/permeability; oral absorption; tight junction in vitro/in vivo correlations;
Transient production of artemisinin in Nicotiana benthamiana is boosted by a specific lipid transfer protein from A. annua
Keywords: حمل کننده ABC; Lipid transfer proteins; ABC transporters; Pleiotropic Drug Resistance protein; Artemisinin; Artemisia annua; Nicotiana benthamiana;
A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: Activation of MRP3 with concurrent inhibition of MRP2 and BCRP
Keywords: حمل کننده ABC; ABC transporters; Lipid excipients; Flavonoids; Multidrug resistance-associated protein;
Explication of Definitional Description and Empirical Use of Fraction of Orally Administered Drugs Absorbed From the Intestine (Fa) and Intestinal Availability (Fg): Effect of P-glycoprotein and CYP3A on Fa and Fg
Keywords: حمل کننده ABC; ABC transporters; intestinal absorption; intestinal metabolism; mathematical model; passive diffusion/transport;
Effects of in vitro exposure to ivermectin and levamisole on the expression patterns of ABC transporters in Haemonchus contortus larvae
Keywords: حمل کننده ABC; ABC transporters; Anthelmintics; Resistance; Haemonchus contortus; P-glycoprotein
In silico analysis of the binding of anthelmintics to Caenorhabditis elegans P-glycoprotein 1
Keywords: حمل کننده ABC; Anthelmintics; Macrocyclic lactones; Nematodes; Caenorhabditis elegans; ABC transporters; Molecular docking; ABC; ATP-binding cassette; ABA; abamectin; AH; anthelmintic; Cel; Caenorhabditis elegans; Ceg; Cylicocylus elongatus; Cgr; Cricetulus griseus; CID
Leishmania tarentolae as a host for heterologous expression of functional human ABCB6 transporter
Keywords: حمل کننده ABC; NTC; nourseothricin; BHI; brain-heart infusion; HRP; horseradish peroxidase; ABC transporters; Membrane protein expression; Leishmania;
Receptors are affected by selection with each Bacillus thuringiensis israelensis Cry toxin but not with the full Bti mixture in Aedes aegypti
Keywords: حمل کننده ABC; ALP; alkaline phosphatase; APN; aminopeptidase N; ABC transporters; ATP-binding cassette transporter; Bti; Bacillus thuringiensis israelensis; SNP; Single Nucleotide Polymorphism; RNA-seq; Bacillus thuringiensis israelensis toxins; Mosquito; Bio-insectici
Drug transporter expression during in vitro differentiation of first-trimester and term human villous trophoblasts
Keywords: حمل کننده ABC; Placenta; Cytotrophoblast; Syncytiotrophoblast; ABC transporters; SLC transporters;
MDR1 P-glycoprotein transports endogenous opioid peptides
Keywords: حمل کننده ABC; P-glycoproteins; ABC transporters; Opioids; Opiates; Blood brain barrier; Bioactive peptides; Transport
Glucagon-like peptide 1 (GLP-1)-based therapy upregulates LXR-ABCA1/ABCG1 cascade in adipocytes
Keywords: حمل کننده ABC; ABC transporters; Adipocytes; Cholesterol; DPP-4 inhibitor; GLP-1;
Transcription profiling of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone
Keywords: حمل کننده ABC; Neurospora crassa; Transcriptional profiling; Xanthones; Acetophenone; ABC transporters; CZT-1
ABCB1 and ABCC4 efflux transporters are involved in methyl parathion detoxification in ZFL cells
Keywords: حمل کننده ABC; ABC transporters; Methyl parathion; Multixenobiotic resistance (MXR); Verapamil;
BCRP protein levels do not differ regionally in adult human livers, but decline in the elderly
Keywords: حمل کننده ABC; ABC transporters; Development; Geriatrics; Obesity
Both aluminum and ABA induce the expression of an ABC-like transporter gene (FeALS3) in the Al-tolerant species Fagopyrum esculentum
Keywords: حمل کننده ABC; ABC transporters; Abscisic acid; Aluminum tolerance; Buckwheat; Fagopyrum esculentum; FeALS3;
Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice
Keywords: حمل کننده ABC; Acetaminophen; ABC transporters; Brain; Nrf2ALT, alanine aminotransferase; P-gp, P-glycoprotein; APAP, acetaminophen; R123, Rhodamine 123; Mrp, multidrug resistance-associated protein; ANOVA, analysis of variance; Ho-1, heme oxygenase; Keap1, Kelch-like E
Regulation of the expression of renal drug transporters in KEAP1-knockdown human tubular cells
Keywords: حمل کننده ABC; ABC transporters; Proximal tubule epithelial cells; KEAP1; NRF2; SLC transporters; Sulforaphane;
P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions
Keywords: حمل کننده ABC; ABC; ATP-binding cassette; ER; endoplasmic reticulum; U.S. FDA; U.S. Food and Drug Administration; NMQ; N-methyl quinidine; P-gp; P-glycoprotein; P-gp; MDR1; Conazoles; Propiconazole; Chemosensitization; ABC transporters;
A longitudinal study of ABC transporter expression in canine multicentric lymphoma
Keywords: حمل کننده ABC; Canine; Lymphoma; ABC transporters; Multidrug resistance; P-glycoprotein;
Ingredients in Fruit Juices Interact with Dasatinib Through Inhibition of BCRP: A New Mechanism of Beverage-Drug Interaction
Keywords: حمل کننده ABC; ABC transporters; drug interactions; drug transport; food interactions; natural products; tyrosine kinase inhibitor;
Quantitative Analysis of the ABCG2 c.421C > A Polymorphism Effect on In Vivo Transport Activity of Breast Cancer Resistance Protein (BCRP) Using an Intestinal Absorption Model
Keywords: حمل کننده ABC; pharmacogenetics; ABC transporters; pharmacokinetics; intestinal absorption; mathematical model
PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer
Keywords: حمل کننده ABC; A1AR; adenosine A1 receptor; ABC transporters; ATP-binding cassette; ABCB1/P-gp/MDR1; P-glycoprotein; ABCG2/BCRP; breast cancer resistant protein; Ang-1; angiopoietin 1; ASCs; Adipose stem cells; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra-lar