Keywords: ABCB1; ATP-binding cassette subfamily B member 1; ABCC2; ATP-binding cassette subfamily C member 2; CDS; clinical decision support; CPIC; clinical pharmacogenetics implementation consortium; CYP; cytochrome P450; MDR 1; multidrug resistance 1 gene; EHR; e
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Keywords: ABCB1; gene coding the efflux transporter P glycoprotein; AUC; area under the concentration time curve; BPAR; biopsy proven acute rejection; C0; residual whole blood tacrolimus concentration; C24h; whole blood tacrolimus concentration at the end of the 24
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
Keywords: Treatment resistance; Cancer stem cells; Cancer progression; Mutation; EMT; EMT transition; ABCB1; ATP-binding cassette, Sub-family B, Member 1; ABCG2; ATP-binding cassette, Sub-family G, Member 2; AKT; V-Akt murine thymoma viral oncogene; APC; adenomatou
Keywords: Cell viability assay; Calcein AM; Sytox Orange; Retinal cell line; Fluorescence assay; Plate reader; 7kCHOL; 7-ketocholesterol; ABCB1; ATP-binding cassette sub-family B member 1 (P-glycoprotein); ABCC1; ATP-binding cassette sub-family C member 1 (Multidru
Keywords: ALK; anaplastic lymphoma receptor tyrosine kinase; ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; APE1; apurinic/apyimidinic endonuclease 1; AKT; v-akt murine thymoma viral oncogene; BER; base excision repair; BRCA1; breast cancer 1; BRCA2
Keywords: Clopidogrel; Genotype-guided antiplatelet therapy; CYP2C19; ABCB1;
Keywords: Ethambutol; BsmI; Cdx2; FokI; CYP24A1; ABCB1;
Keywords: Therapeutic drug monitoring; Antipsychotic; Antidepressant; Psychopharmacology; Psychiatry; Psychopharmacotherapy; Pharmacokinetics; HPLC; Mass spectrometry; LC-MS/MS; ABCB1; ATP-binding cassette sub-family B member 1; AGNP; Arbeitsgemeinschaft für Neuro
Keywords: ABCB1; ATP-Binding Cassette, Sub-Family B; MDR; Multi Drug Resistance; DAPK; Death Associated Protein Kinase; APAF-1; Apoptotic Peptidase Activating Factor 1; MLH1; MutL Homolog 1; MGMT; O-6-Methylguanine-DNA Methyltransferase; KDM5A; Lysine (K)-Specific
Keywords: ABCB1; SLC28A2; IL28B; AKR1; BCRP1; FokI;
Keywords: CYP2C19*2; ABCB1; Clopidogrel;
Keywords: Polychlorinated naphthalenes; Juvenile growth test; Dietary exposure; CYP1A1; ABCB1; Passive dosing; Rainbow trout
Keywords: ABCB1; adenosine triphosphate-binding cassette transporter 1; ASC; apoptosis-associated Speck-like protein containing Caspase recruitment domain; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BD; Behcetʼs disease; Ca2+; calcium; Caspase; cystein
Keywords: MDR cell lines; Multidrug resistance; ABCB transporters; ABCB1; Methylation; Cancer
Keywords: Codeine; Pharmacogenetics; Drug interactions; CYP2D6; ABCB1; Post-mortem;
Keywords: Tramadol; Pharmacokinetics; Pharmacodynamics; CYP2D6; ABCB1; OPRM1
Keywords: Clopidogrel resistance; VASP; CYP2C19; ABCB1; CYP2C9
Keywords: Block copolymer micelles; Intracellular trafficking; Intermembrane transport; NPC1; ORP2; ABCB1;
Keywords: anesthesia – genetics; pharmacogenetics; drug–drug interactions; drug–gene interactions; CYP2D6; CYP3A4; CYP2B6; opioid metabolism; OPRM1; OPRK1; UGT2B7; COMT; GABA; ABCB1; MC1R
Keywords: P-glycoprotein; ABCB1; MDR1; Antidepressant treatment; Side effects; Major depressive disorder
Keywords: ABCB1; African American; allograft failure; APOL1; CAV1; kidney transplantation;
The ABCB1 2677G>T/A polymorphism is associated with baseline blood HDL-cholesterol levels in newly diagnosed hyperlipidemic patients
Keywords: ABCB1; hyperlipidemics; blood lipids; cholesterol;
Association of Allelic Interaction of Single Nucleotide Polymorphisms of Influx and Efflux Transporters Genes With Nonhematologic Adverse Events of Docetaxel in Breast Cancer Patients
Keywords: ABCB1; ABCC2; Pharmacogenetics; SLCO1B3; SNPs;
PXR polymorphisms have impact on the clinical efficacy of clopidogrel in patients undergoing percutaneous coronary intervention
Keywords: ABCB1; ATP-binding cassette, sub-family B, member 1; ACEI; angiotensinconverting enzyme inhibitor; ADP; adenosine diphosphate; ARB; angiotensin receptor blocker; CCB; calcium channel blockers; CHD; Coronary Heart Disease; CLP; clopidogrel; CLPM; clopidogr
ABCB1 C3435T polymorphism is associated with tetrahydrocannabinol blood levels in heavy cannabis users
Keywords: ABCB1; P-glycoprotein 1; Cannabis use disorder; Cannabinoids; Pharmacokinetics; Pharmacogenetics;
UCA1 confers paclitaxel resistance to ovarian cancer through miR-129/ABCB1 axis
Keywords: UCA1; miR-129; ABCB1; Paclitaxel resistance; Ovarian cancer;
FOXP3 rs3761549 polymorphism predicts long-term renal allograft function in patients receiving cyclosporine-based immunosuppressive regimen
Keywords: ABCB1; ATP binding cassette subfamily B member 1; CsA; cyclosporine A; CYP3A4; cytochrome P450 3A4; CYP3A5; cytochrome P450 3A5; eGFR; estimated glomerular filtration rate; Foxp3; forkhead box p3; MMF; mycophenolate mofetil; MPA; mycophenolic acid; MPS; c
Network pharmacology analysis of the anti-cancer pharmacological mechanisms of Ganoderma lucidum extract with experimental support using Hepa1-6-bearing C57 BL/6 mice
Keywords: GL; Ganoderma lucidum; GLE; Ganoderma lucidum extract; HE; hematoxylin and eosin; qRT-PCR; Quantitative reverse transcription- Polymerase Chain Reaction; ABCB1; ATP binding cassette subfamily B member 1; AR; androgen receptor; BCL2; BCL2, apoptosis regula
Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates
Keywords: P-glycoprotein; Efflux ratio; ABCB1; MDR1-P-gp inhibitor; Digoxin; Rhodamine 123; Zosuquidar; Monolayer;
The positive inotropic agent DPI-201106 selectively reverses ABCB1-mediated multidrug resistance in cancer cell lines
Keywords: ABCB1; Multidrug resistance; Modulator; Sodium channel; DPI-201106; MDR; multidrug resistance; ABC; ATP-binding cassette; FCS; fetal calf serum; CCK-8; Cell Counting Kit-8; IMDM; Iscove's Modified Dulbecco's Medium; MTT; 3-(4,5-dimethylthiazol-yl)-2,5-dip
Predicted activity of UGT2B7, ABCB1, OPRM1, and COMT using full-gene haplotypes and their association with the CYP2D6-inferred metabolizer phenotype
Keywords: UGT2B7; ABCB1; OPRM1; COMT; CYP2D6; Comprehensive pharmacogenetics; Molecular autopsy;
C-phycocyanin to overcome the multidrug resistance phenotype in human erythroleukemias with or without interaction with ABC transporters
Keywords: Antiproliferative; Docking; ABCB1; ABCC1;
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
C-Phycocyanin: Cellular targets, mechanisms of action and multi drug resistance in cancer
Keywords: Antitumoral; Antiproliferative; Apoptosis; Tumor specificity; Prevention of metastasis; ABCB1; ABCC1;
ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells
Keywords: ETV7; Ets Variant Gene 7; ETS; E26 Transformation-Specific; DNAJC15; DNAJ Heat Shock Protein family (Hsp40) member C15; ABCB1; ATP Binding Cassette subfamily B member 1; DNMT3A; DNA Methyl-Transferase 3A; 5-Aza; 5-Aza-2â²-deoxycytidine; TNBC; Triple Nega
Monoterpene indole alkaloid azine derivatives as MDR reversal agents
Keywords: ABC; ATP binding cassette; ABCB1; ATP binding cassette subfamily B member 1; ABCG2; ATP binding cassette subfamily G member 2; BCRP; breast cancer resistance protein; BHK-21; baby hamster kidney; CS; collateral sensitivity; FACS; fluorescence-activated ce
Long noncoding RNAs in cancer cells
Keywords: lncRNAs; Cancer biomarker; Oncogene; Drug-resistance; Hallmarks of cancer; ABCB1; ATP-binding cassette; subfamily B and member 1; AFAP1-AS1; actin filament-associated protein 1 antisense RNA 1; ANRIL; antisense non-coding RNA in the ink4 locus; APOC1P1; a
P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice
Keywords: ABCB1; ABCG2; CYP3A enzymes; Encorafenib; Brain penetration;
Effects of UGT2B7, SCN1A and CYP3A4 on the therapeutic response of sodium valproate treatment in children with generalized seizures
Keywords: VPA; sodium valproate; FABP2; fatty acid binding protein 2; ABCB1; ATP binding cassette subfamily B member 1; ABCC2; ATP binding cassette subfamily C member 2; GABA; gamma-aminobutyric acid; ABAT; 4-aminobutyrate aminotransferase; GABR; GABA receptor; SCN
Genotypes and haplotypes of ABCB1 contribute to TAC chemotherapy response in Malaysian triple negative breast cancer patients
Keywords: Triple negative breast cancer; ABCB1; SNPs; Haplotypes; mRNA; Chemoresistance;
HOXB4 knockdown enhances the cytotoxic effect of paclitaxel and cisplatin by downregulating ABC transporters in ovarian cancer cells
Keywords: ABCB1; ATP Binding Cassette Subfamily B Member 1; ABCC1; ATP Binding Cassette Subfamily C Member 1; ABCG2; ATP Binding Cassette Subfamily G Member 2; HOXB13; Homeobox B13; HOXB4; Homeobox B4; LDH; lactate dehydrogenase; PI3K; phosphatidylinositol 3-kinase
A new method measuring the interaction of radiotracers with the human P-glycoprotein (P-gp) transporter
Keywords: AUC; area under the curve; BCRP; breast cancer resistance protein; Ki; equilibrium inhibitory constant; hMDR1; human multiple drug resistance 1; MDCKII; Madin-Darby Canine Kidney cell line; MRP-1; multiple drug resistance protein 1; PET; positron emission
Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro
Keywords: 95%CI; 95% confidential interval; AB; apical-to-basolateral; ABC; ATP-binding cassette; Abcb1; canine P-glycoprotein; ABCB1; human P-glycoprotein; ABCC1; multidrug resistance-associated protein 1; ABCG2; breast cancer resistance protein; BA; basolateral-t
Bisphenol A (BPA) and bisphenol S (BPS) alter the promoter activity of the ABCB1 gene encoding P-glycoprotein in the human placenta in a haplotype-dependent manner
Keywords: BPA/BPS; ABCB1; Polymorphisms; Haplotypes; P-Glycoprotein; Placenta;
Effect of amyloid beta on ATP-binding cassette transporter expression and activity in porcine brain microvascular endothelial cells
Keywords: ABCB1; ABCG2; ABCC5; Nuclear receptors; Amyloid-β; Alzheimer's disease; Porcine brain endothelial cells; ABC; ATP-binding cassette; Aβ(1-42); amyloid-β (1-42); BBB; blood-brain barrier; CAR; constitutive androstane receptor; CAPS; 3-(Cyclohexylam
Discovery of a non-toxic [1,2,4]triazolo[1,5-a]pyrimidin-7-one (WS-10) that modulates ABCB1-mediated multidrug resistance (MDR)
Keywords: Multidrug resistance (MDR); ABC transporters; ABCB1; Triazolo [1,5-a]pyrimidin-7-one;
Comparison of mechanistic transport cycle models of ABC exporters
Keywords: ABC transporter; ABCB1; P-glycoprotein; Molecular dynamics simulations; Transport cycle; Mechanistic models;
The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact
Deubiquitylating enzymes as cancer stem cell therapeutics
Keywords: Protein-IPSC; protein-induced pluripotent stem cells; CSCs; cancer stem cells; DUBs; deubiquitylating enzymes; ESCs; embryonic stem cells; PTMs; post-translational modifications; AML; acute myelogenous leukemia; USP/UBP; ubiquitin-specific processing prot