P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacological Research - Volume 129, March 2018, Pages 414-423

Jing Wang, Changpei Gan, Rolf W. Sparidans, Els Wagenaar, Stéphanie van Hoppe, Jos H. Beijnen, Alfred H. Schinkel,