Keywords: αSMA; alpha-smooth muscle actin; ABCG2; ATP-binding cassette sub-family G member 2; ACE; angiotensin-converting enzyme; ASK1; apoptosis signal-regulating kinase 1; BF; bright field; CD90; cluster of differentiation 90; CF; cardiac fibroblast; COPD; chron
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Keywords: 5-FU; 5-Fluorouracil; ABCB5; ATP-binding cassette sub-family B member 5; ABCC2; ATP-binding cassette sub-family C member 2; ABCG2; ATP-binding cassette sub-family G member 2; ACs; Anthocyanins; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; AP
Keywords: ABCG2; Antiemetic agents; Chemotherapy-induced nausea and vomiting; Genetic factors; Single nucleotide polymorphism;
Keywords: Anticancer therapy; Autophagy; Cancer stem cells; Chemoresistance; Stemness; 5-FU; 5-fluorouracil; ABC; transporter; ATP; binding cassette transporters; ABCC3; ATP Binding Cassette Subfamily C Member 3; ABCG2; ABC transporter gene2; ALDH; aldehyde dehydro
Keywords: Mrp1; Multidrug resistance proteins 1; Mrp2; Multidrug resistance proteins 2; Mrp3; Multidrug resistance proteins 3; Mrp4; Multidrug resistance proteins 4; Abcg2; ATP-binding cassette sub-family G member 2; Mrp transporters; Abcg2; Rat liver; Development;
Keywords: Treatment resistance; Cancer stem cells; Cancer progression; Mutation; EMT; EMT transition; ABCB1; ATP-binding cassette, Sub-family B, Member 1; ABCG2; ATP-binding cassette, Sub-family G, Member 2; AKT; V-Akt murine thymoma viral oncogene; APC; adenomatou
Keywords: ABC; ATP-binding cassette; BCRP/ABCG2; breast cancer resistance protein; Bz; benzoyl; FTC; fumitremorgin C; mBu; methyl isobutyl; LBE; lowest binding energies; MDR; multidrug resistance; MRP1; multidrug-resistance-associated protein 1; POP; polyoxypregnan
Keywords: Genome-wide association studies; Gout; Hyperuricemia; ABCG2; SLC2A9; Urate; Uric acid;
Keywords: ABCG2; ATP binding cassette subfamily G member 2; CPF; chlorpyrifos; hCG; human chorionic gonadotrophin; MDR1; multi-drug resistance 1 gene; OP; Organophosphate; P-gp; P-glycoprotein 1; PSG; pregnancy specific glycoprotein; STB; syncytiotrophoblast; vCTB;
Keywords: Ovarian cancer; Chemotherapy resistance; Natural compounds; Autophagy; Apoptosis; Ovarian cancer stem-like cells; ABCG2; ATP-binding cassette G2; AE; Amla extracts; Akt; protein kinase B; ALDH1; aldehyde dehydrogenase 1; ARE; antioxidant-response element;
Keywords: ABCC; ATP-binding cassette sub-family C; ABCG2; ATP-binding cassette sub-family G member 2 (BCRP); DHFA; Dihydroferulic acid; DMCA; 3,4-dimethoxycinnamic acid; FA; Ferulic acid; FA-glu; Ferulic acid-4-O-glucuronide; FA-sul; Ferulic acid-4-O-sulfate; HT; H
Keywords: ABCG2; ATP binding cassette subfamily G member 2; alt-EJ; alternative end joining; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3 related; Aundiff; undifferentiated spermatogonia; DDR; DNA damage response; BAX; BCL2-associated X p
Keywords: ABCG2; ATP Binding Cassette subfamily G Member 2; ANCR; antidifferentiation non-coding RNA; A-T; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; BCC; basal cell carcinoma; Bcl-2; B-Cell CLL/Lymphoma 2; BCNS; basal-cell nevus syndrome; BCRP1; br
Keywords: Red cell membrane proteins; Biomarkers; Insulin receptor; GLUT1 transporter; ABCA1; ABCB6; ABCG2; PMCA; Erythrocyte membrane
Keywords: PDGF-A; platelet-derived growth factor-A; CK2; casein kinase 2; Bcl-2; B-cell lymphoma-2; PARP; poly-(ADP-ribose) polymerase; IAP; inhibitor of apoptosis protein; XIAP; X-linked inhibitor of apoptosis protein; 8-tBid; caspase-8-cleaved Bid; CBF1; C-repeat
Keywords: EGFR; epidermal growth factor receptor; NSCLC; non-small cell lung cancer; TKI; tyrosine kinase inhibitor; WT; wild type; KRAS; Kirsten RNA associated rat sarcoma 2 virus gene; PTEN; phosphatase and tensin homolog; HGF; hepatocyte growth factor; IGF1R; in
Keywords: Gout; Urate; Gene; Association; Genome-wide association studies; SLC2A9; ABCG2;
Keywords: Uric acid; Diabetic kidney disease; SLC2A9; ABCG2; Single nucleotide polymorphisms
Effect of ABCG2, OCT1, and ABCB1 (MDR1) Gene Expression on Treatment-Free Remission in a EURO-SKI Subtrial
Keywords: ABCG2; Biomarker; CML; Imatinib; Prediction;
Polymorphisms of ABCG2 and its impact on clinical relevance
Keywords: ABCG2; SNPs; Gout; Cancer; Epilepsy; Atorvastatin; Alzheimer's disease;
SDF-1/CXCR4 axis promotes the growth and sphere formation of hypoxic breast cancer SP cells by c-Jun/ABCG2 pathway
Keywords: CXCR4; ABCG2; SP cells; JNK/c-Jun; Hypoxia; Breast cancer;
Correlation between adenosine triphosphate (ATP)-binding cassette transporter G2 (ABCG2) and drug resistance of esophageal cancer and reversal of drug resistance by artesunate
Keywords: ABCG2; adenosine triphosphate-binding cassette transporter G2; ADM; art and/or doxorubicin; AML; acute myeloid leukemia; Art; artesunate; ATP; adenosine triphosphate; EB; ethidium bromide; FBS; fetal bovine serum; FCM; flow cytometry; IHC; immunohistochem
Effect and mechanism of dioscin from Dioscorea spongiosa on uric acid excretion in animal model of hyperuricemia
Keywords: Dioscin; Tigogenin; URAT1; ABCG2; Hyperuricemia; Uric acid excretion;
Olmutinib (HM61713) reversed multidrug resistance by inhibiting the activity of ATP-binding cassette subfamily G member 2 in vitro and in vivo
Keywords: ABC; adenosine triphosphate (ATP)-binding cassette; ABCG2; ABC transporter subfamily G member 2; DDP; cisplatin; DMEM; Dulbecco׳s modified Eagle׳s medium; DMSO; dimethyl sulfoxide; DOX; doxorubicin; FTC; fumitremorgin C; IAAP; iodoarylazidoprazosin; MDR
Monoterpene indole alkaloid azine derivatives as MDR reversal agents
Keywords: ABC; ATP binding cassette; ABCB1; ATP binding cassette subfamily B member 1; ABCG2; ATP binding cassette subfamily G member 2; BCRP; breast cancer resistance protein; BHK-21; baby hamster kidney; CS; collateral sensitivity; FACS; fluorescence-activated ce
P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice
Keywords: ABCB1; ABCG2; CYP3A enzymes; Encorafenib; Brain penetration;
ABCG2-mediated suppression of chlorin e6 accumulation and photodynamic therapy efficiency in glioblastoma cell lines can be reversed by KO143
Keywords: Photodynamic therapy; Chlorin e6; ABCG2; Glioblastoma; Cancer stem cells;
Inhibiting ABCG2 could potentially enhance the efficacy of hypericin-mediated photodynamic therapy in spheroidal cell models of colorectal cancer
Keywords: Colorectal cancer; Hypericin; Photodynamic therapy; ABCG2; Multicellular tumour spheroids; Ko143;
HOXB4 knockdown enhances the cytotoxic effect of paclitaxel and cisplatin by downregulating ABC transporters in ovarian cancer cells
Keywords: ABCB1; ATP Binding Cassette Subfamily B Member 1; ABCC1; ATP Binding Cassette Subfamily C Member 1; ABCG2; ATP Binding Cassette Subfamily G Member 2; HOXB13; Homeobox B13; HOXB4; Homeobox B4; LDH; lactate dehydrogenase; PI3K; phosphatidylinositol 3-kinase
Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro
Keywords: 95%CI; 95% confidential interval; AB; apical-to-basolateral; ABC; ATP-binding cassette; Abcb1; canine P-glycoprotein; ABCB1; human P-glycoprotein; ABCC1; multidrug resistance-associated protein 1; ABCG2; breast cancer resistance protein; BA; basolateral-t
Effect of amyloid beta on ATP-binding cassette transporter expression and activity in porcine brain microvascular endothelial cells
Keywords: ABCB1; ABCG2; ABCC5; Nuclear receptors; Amyloid-β; Alzheimer's disease; Porcine brain endothelial cells; ABC; ATP-binding cassette; Aβ(1-42); amyloid-β (1-42); BBB; blood-brain barrier; CAR; constitutive androstane receptor; CAPS; 3-(Cyclohexylam
The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma
Keywords: Nasopharyngeal carcinoma; IRF6; Cancer stem cells; ABCG2; Transcription;
Repression of adenosine triphosphate-binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury
Keywords: ABCG2; Brain endothelial cell; Estrogen; Glutathione; Ischemic stroke; Neuroprotection;
Metronomic vinorelbine is directly active on Non Small Cell Lung Cancer cells and sensitizes the EGFRL858R/T790M cells to reversible EGFR tyrosine kinase inhibitors
Keywords: ABCG2; ATP-binding cassette sub-family G member 2; CI; combination index; D-VNR; deacetyl-vinorelbine; EGFR; epidermal growth factor receptor; FBS; fetal bovine serum; IC50; inhibitory concentration 50; mVNR; metronomic vinorelbine; NSCLC; Non Small Cell
Epidermal growth factor receptor (EGFR) inhibitor PD153035 reverses ABCG2-mediated multidrug resistance in non-small cell lung cancer: In vitro and in vivo
Keywords: PD153035; Tyrosine kinase inhibitor; Multidrug resistance; EGFR inhibitor; ABCG2;
Regulation of ABCG2 by nuclear factor kappa B affects the sensitivity of human lung adenocarcinoma A549 cells to arsenic trioxide
Keywords: Arsenic trioxide; ABCG2; NF-κB; Drug sensitivity;
Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure
Keywords: α/β-Cardiac Myosin; Heavy chain Alpha and Beta Cardiac Myosin; ABCG2; ATP-Binding Cassette sub-family G member 2; ANOVA; Analysis of Variance; DMEM; Dulbecco's Modified Eagle Medium; DMSO; Dimethyl Sulfoxide; DPBS; Dulbecco's Phosphate-Buffered Sali
Role of the efflux transporters BCRP and MRP1 in human placental bio-disposition of pravastatin
Keywords: ALP; alkaline phosphatase; AMP; adenosine monophosphate; ATP; adenosine triphosphate; BCRP; breast cancer resistance protein; ABCG2; ATP-binding cassette sub-family G member 2; DHA; dihydroalprenolol; IOVs; inside-out vesicles; MRPs; multidrug resistance-
Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine
Keywords: Blood-brain barrier; P-glycoprotein; ABCG2; AZT; Inhibition;
Abcb1a but not Abcg2 played a predominant role in limiting the brain distribution of Huperzine A in mice
Keywords: Huperzine A; Alzheimer's disease; Brain distribution; ABCB1; Brain to plasma concentration ratio; ABCB1; ATP Binding Cassette Subfamily B Member 1; ABCG2; ATP Binding Cassette Subfamily G Member 2; BBB; Blood-Brain Barrier; BCRP; Breast Cancer Resistant P
The Breast Cancer Resistance Protein (BCRP/ABCG2) influences the levels of enterolignans and their metabolites in plasma, milk and mammary gland
Keywords: ABC; ATP-binding cassette; ABCG2; ATP-binding cassette subfamily G2; END; enterodiol; ENL; enterolactone; SDG; secoisolariciresinol diglucoside; SECO; secoisolariciresinol; UPLC-QTOF-MS; ultra-performance liquid chromatography quadrupole time-of-flight ma
Design, synthesis and biological evaluation of benzamide and phenyltetrazole derivatives with amide and urea linkers as BCRP inhibitors
Keywords: ABCG2; BCRP inhibitors; Multidrug resistance; Benzamide and phenyltetrazole derivatives; Cytotoxicity and reversal assay;
Down-regulation of the placental BCRP/ABCG2 transporter in response to hypoxia signaling
Keywords: BCRP; ABCG2; Placenta; Transporter; Hypoxia;
In this issueExpression of MRP1 and ABCG2 is associated with adverse clinical outcomes of papillary thyroid carcinoma with a solid component
Keywords: Solid variant; Papillary thyroid carcinoma; Cancer stem cell; MRP1; ABCG2;
Contrasting roles of the ABCG2 Q141K variant in prostate cancer
Keywords: ABCG2; Docetaxel; Folate; Prostate cancer; Q141K variant;
Metabolism of KO143, an ABCG2 inhibitor
Keywords: ABCG2; KO143; Carboxylesterase; Drug metabolism; Drug design;
Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation
Keywords: Afatinib; Tyrosine kinase inhibitor; ABCB1; ABCG2; Brain accumulation; Oral availability;
Research ArticleGene expression changes in colon tissues from colorectal cancer patients following the intake of an ellagitannin-containing pomegranate extract: a randomized clinical trial
Keywords: ABCG2; ATP-binding cassette subfamily G member 2 gene; APC; adenomatous polyposis coli gene; BIRC5; baculoviral inhibitor of apoptosis repeat-containing 5 gene; CASP3; apoptosis-related cysteine peptidase (caspase 3) gene; CDKN1A; cyclin-dependent kinase
Original ArticleTyrphostin RG14620 selectively reverses ABCG2-mediated multidrug resistance in cancer cell lines
Keywords: ABC transporter; ABCG2; EGFR inhibitor; Multidrug resistance; Tyrphostin RG14620; MDR; multidrug resistance; ABC; ATP-binding cassette; EGFR; epidermal growth factor receptor; FCS; fetal calf serum; CCK-8; Cell Counting Kit-8; IMDM; Iscove's Modified Dulb
Suppression of ABCG2 mediated MDR in vitro and in vivo by a novel inhibitor of ABCG2 drug transport
Keywords: ABC; ATP-binding cassette; ABCB1; ABC transporter-subfamily B member 1; ABCG2; ABC transporter-subfamily G member 2; MDR; multidrug resistance; Multi-drug resistance; ATP-Binding cassette; Breast cancer resistance protein; Reversal;