Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; ACN; acetonitrile; ADMET; absorption, distribution, metabolism, excretion and toxicity; Caco2; in vitro Caco2 cell permeability (Human colorectal carcinoma); ANN; artificial neural networks; CADD; computer-aided drug design; DAD; diode array detector; ECC
مقالات ISI جذب، توزیع، متابولیسم، دفع و سمیت (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; AD; Alzheimer's disease; NFT; neurofibrillary tangles; ChE; cholinesterase; NMDA; N-methyl-D-aspartate; TCM; Traditional Chinese Medicine; MOA; mechanisms of action; TCMSP; traditional Chinese medicine systems pharmacology; TCMID; traditional Chinese medi
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; DILI; drug-induced liver injury; HLA; human leucocyte antigen; DAMPs; the damage associated molecular pattern molecules; ADMET; absorption, distribution, metabolism, excretion and toxicity; GST; glutathione-S-transferase; ROS; reactive oxygen species; JNK
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; ADME; absorption, distribution, metabolism and excretion; ADMET; absorption, distribution, metabolism, excretion and toxicity; FDA; USA Food and Drug Administration; GWAS; genome-wide association study; mTOR; mammalian target of rapamycin; NME; new molecu
Multiple quantitative structure-activity relationships (QSARs) analysis for orally active trypanocidal N-myristoyltransferase inhibitors
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; QSAR; TbNMT; Pyrazole sulphonamides; Human African trypanosomiasis; TbNMT; Trypanosoma brucei N-myristoyltransferase; HAT; Human African Trypanosomiasis; GA; Genetic algorithm; MLR; Multiple linear Regression; QSAR; Quantitative structure-activity analysi
Binding affinity toward human prion protein of some anti-prion compounds - Assessment based on QSAR modeling, molecular docking and non-parametric ranking
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; ADMET; absorption, distribution, metabolism, excretion and toxicity; ANN; artificial neural networks; ANNR; artificial neural networks regression; BBB; blood-brain barrier; BFGS; Broyden-Fletcher-Goldfarb-Shanno algorithm; BSE; bovine spongiform encephalo
Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; Trypanosoma cruzi; Naphthoquinones; Trypanocidal activity; Chemotherapy; CD; Chagas disease; Bz; Benznidazole; Nif; Nifurtimox; ROS; Reactive oxygen species; CC50; Concentration of compound that reduces 50% of mammalian cell viability; IC50; Concentration
PyDescriptor: A new PyMOL plugin for calculating thousands of easily understandable molecular descriptors
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; Molecular descriptors; PyMOL; PyDescriptor; QSAR; Interpretation; OECD; Organisation for Economic Co-operation and Development; WHO; World health organisation; ADMET; Absorption, Distribution, Metabolism, Excretion and Toxicity; OLS; Ordinary Least Square
QSAR modeling for anti-human African trypanosomiasis activity of substituted 2-Phenylimidazopyridines
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; Anti-HAT activity; QSAR; Substituted 2-Phenylimidazopyridines; HAT; Human African Trypanosomiasis; GA; Genetic algorithm; MLR; Multiple linear Regression; QSAR; Quantitative structure-activity analysis; WHO; World health organization; ADMET; Absorption, D
The application of molecular modelling in the safety assessment of chemicals: A case study on ligand-dependent PPARγ dysregulation
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; ADMET; absorption, distribution, metabolism, excretion and toxicity; AOP; adverse outcome pathway; BHK21 ATCC CCL10; baby hamster kidney cell line from the American Type Culture Collection; CAS; chemical abstracts service; CoMSIA; comparative molecular si
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; 3OH-Qi; 3-hydroxy-quinidine; ADME-Tox; absorption, distribution, metabolism, excretion and toxicity; CP100356; N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine; CYP; cytochrome P450; DDI(s); drug
Prediction of pharmacokinetic and toxicological parameters of a 4-phenylcoumarin isolated from geopropolis: In silico and in vitro approaches
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; ADME/Tox; absorption, distribution, metabolism, excretion and toxicity; CNM; cinnamoyloxy-mammeisin; HPLC; high performance liquid chromatography; HREIMS; high-resolution electron-spray ionization mass spectrometry; MeOH; methanol; NMR; nuclear magnetic r
Coupling ultra-high-pressure liquid chromatography with mass spectrometry for in-vitro drug-metabolism studies
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; ADC; Analog-to-digital converter; ADMET; Absorption, distribution, metabolism, excretion and toxicity; APCI; Atmospheric pressure chemical ionization; CYP; Cytochrome P450; DDI; Drug-drug interaction; DMPK; Drug metabolism and pharmacokinetics; DT; Dwell
Dendrimer space concept for innovative nanomedicine: A futuristic vision for medicinal chemistry
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; PK; pharmacokinetic; PD; pharmacodynamic; PK/PD; pharmacokinetic/pharmacodynamic; RES; reticuloendothelial system; EPR effect; enhanced permeability and retention effect; ADMET; absorption, distribution, metabolism, excretion and toxicity; logP; octanolâ
Potential virtual lead identification in the discovery of renin inhibitors: Application of ligand and structure-based pharmacophore modeling approaches
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; Ligand and structure-based pharmacophore; Renin; Blood pressure; Database screening; Molecular docking; RAS; renin-angiotensinogen system; ACE; angiotensin-converting enzyme; PDB; protein data bank; DS; discovery studio; Pharm-A; pharmacophore A; HA; hydr
Prediction of the deleterious nsSNPs in ABCB transporters
Keywords: جذب، توزیع، متابولیسم، دفع و سمیت; SNP; single nucleotide polymorphism; nsSNPs; non-synonymous SNPs; ABCB; ATP-binding cassette B; RPLS; ridge partial least square; LDA; linear discriminant analysis; 3D; 3-dimensional; SIFT; sorting intolerant from tolerant; ÎÎG; relative stability chang