Keywords: NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; FC; free cholesterol; VLDL; very low density lipoprotein; LDL; low density lipoprotein; mTOR; mechanistic target of rapamycin signaling; AMPK; AMP-activated protein kinase; TG; t
مقالات ISI (ترجمه نشده)
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Keywords: ACAT; acyl-coenzyme A:cholesterol acyltransferases; BSH; bile salt hydrolase; CFU; colony-forming unit; FAS; fatty acid synthase; FXR; farnesoid X receptor; GA; gum Arabic; GLP; glucagon-like peptides; HDL-C; high density lipoproteins cholesterol; HFD; hi
Keywords: apoA-I; apolipoprotein A-I; apoB; apolipoprotein B; apoE; apolipoprotein E; ABCA1; ATP-cassette binding transporter A1; ABCG1; ATP-cassette binding transporter G1; ACAT; acyl CoA cholesterol acyl transferase; ATP; adenosine triphosphate; CAD; coronary art
Keywords: 27-HC; 27-hydroxycholesterol; ER; estrogen receptor; CYP27A1; cytochrome P450, family 27, subfamily A, polypeptide 1; LXR; liver X receptor; BRCA1 and BRCA2; Breast cancer 1 and 2; LDL; low density lipoprotein; HDL; high density lipoprotein; ApoE; apolipo
Keywords: ACAT; acyl coenzyme A:cholesterol acyltransferase; ATP; binding cassette; CC; curcumin group; CHD; coronary heart disease; CVD; cardiovascular disease; CYP7A; cholesterol 7alpha-hydroxlyase; HDL-C; HDL-cholesterol; HMG-CoA reductase; 3-hydroxy-3-methyl-gl
Keywords: ACAT; Aged Care Assessment Team; ADE; adverse drug event; BZD; benzodiazepine; DAA; dose administration aid; DDD; defined daily dose; GP; general medical practitioner; HYVET; Hypertension in the Very Elderly Trial; MAC; Medication Advisory Committee; PART
Keywords: ABC; ATP-binding casette; ACAT; acyl-CoA:cholesterol acyltransferase; ALLO; allopregnanolone; CAH; congenital adrenal hyperplasia; CESD; cholesterol ester storage disease; CoA; coenzyme A; CYP; cytochrome P450; DSD; Disordered sexual development; ER; endo
Keywords: AA; arachidonic acid; ABCA1; ATP binding cassette transporter A1; ACAT; acyl coenzyme A: cholesterol acyl transferase; apo; apolipoprotein; CE; cholesteryl esters; CHD; coronary heart disease; DHA; docosahexaenoic acid; DPA; docosapentaenoic acid; EPA; ei
Keywords: ACAT; acyl-coenzyme A:cholesterol acyl transferase; DChol; 6-dansyl-cholestanol; RChol; 6-rhodamine-cholestanol; BChol; bodipy cholesterol (=Â TopFluo Chosterol); BODIPY; boron dipyrro methane; BSA; bovine serum albumin; DOPC; 1,2-dioleoyl-sn-glycero-3-ph
Keywords: ACAT; Advanced Compartmental Absorption and Transit; BCS; biopharmaceutical drug classification system; CAT; Compartmental Absorption and Transit; FD; fast dissolving; GR; gastric release; IR; immediate release; IVIVC; in vivo/in vitro correlations; MAE;
Keywords: ACAT; acyl-CoA:cholesterol acyltransferase; DGAT; acyl-CoA:diacylglycerol acyltransferase; DW; dry weight; FAR; fatty acyl-CoA reductase; MGAT; acyl-CoA:monoacylglycerol acyltransferase; Ric; ricinoleic acid; TAG; triacylglycerols; WE; wax esters; WS; wax
Keywords: Cancer stem-like cells; Mevalonate cascade; Ras; Rho; Stemness; Statins; Yap; ACAT; acetoacetyl-CoA transferase; acetyl-CoA; acetyl-coenzyme A; Arp2/3; actin-related protein 2/3 (actin polymerizing complex); BPs; bisphosphonates; CAMs; cell adhesion molec
Keywords: ACAT; Acyl-coenzyme A: Cholesterol Acetyltransferase; AGPAT2; 1-acylglycerol-3-phosphate-O-acyltransferase-2; AsD; Atherogenic diet; BMT; Bone marrow transplant; CGL; Congenital generalized lipodystrophy; IDL; Intermediate-density lipoprotein; LDLR; Low-d
Keywords: FA; fatty acid; LD; lipid droplet; ER; endoplasmic reticulum; DAG; diacylglycerol; DGAT; diacylglycerol O-acyltransferase; PL; phospholipid; PDAT; phospholipid:diacylglycerol O-acyltransferase; ACAT; acyl-CoA:cholesterol O-acyltransferase; PA; phosphatidi
Keywords: APO; apolipoprotein; ACS; acyl-CoA synthetase; ACSL; acyl-CoA synthetase, long chain; ACAT; acyl-CoA:cholesterol acyltransferase; AGPAT; acylglycerophosphate acyltransferase; ATGL; adipocyte triglyceride lipase; 3BHS1; 3-Beta-hydroxysteroid dehydrogenase;
Keywords: 24OHC; 24S-Hydroxycholesterol; 27OHC; 27-Hydroxycholesterol; ABC; ATP-binding cassette transporter; ACAT; Acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; ApoE; Apolipoprotein E; BACHD; Bacterial artificial chromosome HD; BDNF; Brain-derived n
Keywords: SL; sphingolipid; S1P; sphingosine 1-phosphate; GCS; glucosylceramide synthase; GC; glucosylceramide; AC; ceramidase; SphK; sphingosine kinase; PPMP; D-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol; PDMP; D-threo-1-phenyl-2-decanoylamino-3-mo
Keywords: 11β-HSD; 11β-hydroxysteroid dehydrogenase; 17β-HSD; 17β-hydroxysteroid dehydrogenase; ACAT; acyl-CoA:cholesterol acyltransferase; DTT; dithiothreitol; DMEM; Dulbecco's modified Eagle's medium; ÎR; endoplasmic reticulum; GFP; green-fluorescent protein
Keywords: ABC; ATP binding cassette; ACAT; Acyl CoA: cholesterol acyltransferase; ACBD1/3; acyl CoA binding domain 1/3; AFG3L2; AFG3-like AAA ATPase 2; AIM/Spα; apoptosis inhibitor expressed by macrophages; ANT; adenine nucleotide transporter; Apo; apolipoprotein;
Keywords: ABCG; ATP-binding cassette sub-family G; AC; atherogenic control; ACAT; Acyl-coenzyme A cholesterol acyltrasnferase; BBR; berberine; EMEM; Eagle's Minimum Essential Medium; HBSS; Hank's buffered salt solution; IRMS; isotope ratio mass spectrometry; LDL-C;
Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: 7-KC; 7 ketocholesterol; ACAT; acyl-CoA cholesterol acyl transferase; CHEH; cholesterol-5-6-epoxide hydrolase; CNS; central nervous system; CT; cholestane 3β-5α-6β triol; EC; epoxycholesterol; EGF; epidermal growth factor; ER; endoplasmic reticulum; ER
Keywords: TRL; triglyceride-rich lipoproteins; ApoB48R; apolipoprotein-B48 receptor; HPSO; high-palmitic sunflower oil; ROO; olive oil; VEFO; mixture of vegetable and fish oils; SFA; saturated fatty acids; MUFA; monounsaturated fatty acids; PMA; phorbol 12-myristat
Keywords: 1,25(OH)2D; 1,25 dihydroxy vitamin D (calcitriol); 3βHSD; 3β-hydroxysteroid dehydrogenase; ACAT; acyl transferase; ACTH; adrenocorticotropic hormone; ANT; adenine nucleotide transporter; ER; endoplasmic reticulum; CRAC; cholesterol recognition amino aci
Mining Ferula gummosa transcriptome to identify miRNAs involved in the regulation and biosynthesis of terpenes
Keywords: bp; base pair(s); RNA-seq; ribonucleic acid sequencing; KEGG; The Kyoto Encyclopedia of Genes and Genome; BLAST; basic local alignment search tool; TF; transcription factor; TP; terpene synthesis; GO; gene ontology; E-value; expectation value; MVA; mevalo
Network analysis reveals the co-expression of sugar and aroma genes in the Chinese white pear (Pyrus bretschneideri)
Keywords: SS, SUS; sucrose synthase; INV; invertase; SPS; sucrose phosphate synthase; SDH; sorbitol dehydrogenase; S6PDH; sorbitol-6-phosphate dehydrogenase; SUTs; sucrose transporters; HTs; hexose transporters; SOTs; sorbitol transporters; LOX; lipoxygenase; HPL;
Proposal of a new thraustochytrid genus Hondaea gen. nov. and comparison of its lipid dynamics with the closely related pseudo-cryptic genus Aurantiochytrium
Keywords: ACAA; 3-ketoacyl-CoA thiolase; ACAT; acetyl-CoA acetyltransferase; ACP; acyl carrier protein; CACT; carnitine-acylcarnitine translocase; CCT; CTP:phosphocholine cytidylyltransferase; CDP-DAG; cytidyldiphosphate-diacylglycerol; CDP-EtA; cytidyldiphosphate-
19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system
Keywords: ACAT; acyl-CoA: cholesterol acyltransferase; CE; cholesterol ester; 19MD; chromosome 19 microdeletion; ER; endoplasmic reticulum; FCS; fetal calf serum; GlcCer; glucosylceramide; HBSS; Hank's buffered salt solution; HPBCD; 2-hydroxypropyl-β-cyclodextrin;
Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts
Keywords: ACAT; acyl Coenzyme A acyl transferase; Alexa647-Tf; Alexa647-tagged transferrin; 13C3-cholesterol; cholesterol with heavy carbon (C13) at position 3; CHO; Chinese Hamster Ovarian; ER; endoplasmic reticulum; D; diffusion coefficient; DHE; dehydroergostero
The heparan sulfate proteoglycan grip on hyperlipidemia and atherosclerosis
Keywords: ACAT; Acyl-CoA:cholesterol acyltransferase; ADAM17; a disintegrin and metalloproteinase 17; APO; apolipoprotein; COL18; collagen XVIII; CS/DS; chondroitin sulfate/dermatan sulfate; FLOT1; flotilin-1; GLCE; C5 epimerase; GPIHBP1; glycosylphosphatidylinosit
Use of biorelevant dissolution and PBPK modeling to predict oral drug absorption
Keywords: Biorelevant dissolution; Weak base; PBPK modeling; BCS class II; pH dependent solubility; ACAT; advanced compartmental absorption and transit model; ADAM; advanced dissolution, absorption and metabolism model; API; active pharmaceutical ingredient; ASD;
Mechanistic prediction of food effects for Compound A tablet using PBPK model
Keywords: Food effects; PBPK; ACAT; Prediction; Pharmacokinetic;
Effect of the pulmonary deposition and in vitro permeability on the prediction of plasma levels of inhaled budesonide formulation
Keywords: ACAT; advanced compartmental absorption and transit; ADRM; additional dosage route module; ALE; air-liquid interface exposure; API; active pharmaceutical ingredient; APSD; aerodynamic particle size distribution; AUC; area under the curve; CF; cystic fibro
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration
Keywords: RPE; retinal pigment epithelium; UC; unesterified cholesterol; EC; esterified cholesterol; Fib3; EFEMP1/Fibulin3; AMD; age-related macular degeneration; ApoB; Apolipoprotein B; BrM; Bruch's membrane; HDL; high-density lipoprotein; FCS; fetal calf serum;
Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors
Keywords: CETP inhibitor; Pentacyclic triterpenes; Non-HDL-C; Dyslipidemia; CVDs; cardiovascular diseases; CETP; cholesteryl ester transfer protein; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; VLDL; very-low-density lipo
Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1-AKT-mTOR Axis in Mice
Keywords: Cholesterol; Cholestyramine; Fatty Liver; Nuclear Receptor; ACAT; acyl-CoA:cholesterol acyltransferase; CE; cholesterol ester; ChTM; cholestyramine; CQ; chloroquine; CYP7A1; cholesterol 7α-hydroxylase; DIO; diet-induced obesity; ER; endoplasmic reticulum
Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism
Keywords: ACAT; acyl-CoA:cholesterol acyltransferase; ApoE; apolipoprotein E; DGAT; acyl-CoA:diacylglycerol acyltransferase; I-DGAT1; intestine-specific; Inh-DGAT1; DGAT1 inhibitor-treated; GLP-1; glucagon-like peptide 1; HF/HCD; high-fat/high-cholesterol diet; MTP
In vitro and in silico characterisation of Tacrolimus released under biorelevant conditions
Keywords: Tacrolimus (PubChem CID: 5282315); ACAT; advanced compartmental and transit; ADME; absorption, distribution, metabolism and excretion; ANOVA; analysis of variance; API; active pharmaceutical ingredient; BCS; biopharmaceutics classification system; CL; cle
Decreased OxLDL uptake and cholesterol efflux in THP1 cells elicited by cortisol and by cortisone through 11β-hydroxysteroid dehydrogenase type 1
Keywords: Cortisol; Cortisone; 11β-hydroxysteroid dehydrogenase 1; 11β-hydroxysteroid dehydrogenase 2; THP1 macrophages; Foam cells; EMR1; epidermal growth factor like module-containing mucin-like hormone receptor-like1; CD163; Cluster of Differentiation 163; MMR
Diagnostic tests for Niemann-Pick disease type C (NP-C): A critical review
Keywords: 7-KC; 7-Ketocholesterol; ACAT; Acyl-CoA:cholesterol acyltransferase; ASMDs; Acid sphingomyelinase deficiencies; BMP; Bis(monoacylglycero)phosphate; C-triol; Cholestane-3β,5α,6β-triol; EOA; Early-onset ataxia; GC/MS; Gas chromatography-mass spectromet
Brain cortical cholesterol metabolism is highly affected by human APP overexpression in mice
Keywords: Alzheimer's disease; Aβ; Cholesterol; Amyloid precursor protein overexpression; Mouse model; APPSL; AD; Alzheimer's disease; Aβ; amyloid beta; ACAT; Acetyl-CoA acetyltransferases; APP; amyloid precursor protein; ApoB-100; apolipoprotein B-100; ApoE; apo
SND1 overexpression deregulates cholesterol homeostasis in hepatocellular carcinoma
Keywords: ACAT; acyl-coenzyme A:cholesterol acyltransferase; CD; cyclodextrin; CE; cholesteryl ester; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; FC; free cholesterol; HCC; hepatocellular carcinoma; HMGCR; hydroxymethylglutaryl-coenzyme A reductase; INSIG;
Chylomicrons: Advances in biology, pathology, laboratory testing, and therapeutics
Keywords: ACAT; acyl CoA acyl transferase; Angptl3; angiopoietin-like protein 3; Angptl4; angiopoietin-like protein 4; Angptl8; angiopoietin-like protein 8; apo; apolipoprotein; apobec 1; apoB mRNA editing enzyme 1; CM; chylomicron; CMs; chylomicrons; COPII; coat p
Oxysterols: From cholesterol metabolites to key mediators
Keywords: ABC; ATP-binding cassette; ACAT; acyl-coenzyme A cholesterol acyltransferase; C4; 7-hydroxycholestenone; CA; cholestanoic acid; CH25H; cholesterol-25-hydroxylase; ChEH; cholesterol epoxide hydrolase; CNS; central nervous system; CSF; cerebrospinal fluid;
Electrospun polyimide nanofibers and their applications
Keywords: AAI; [CH3COCHC(O)CH3]3Fe; AAPTMI; 5(6)-amino-1-(4â²-aminophenyl)-1,3-trimethylindane; ACAT; N,Nâ²-bis(4â²-aminophenyl)-1,4-quinonenediimine; AIE; aggregation-induced emission; BDAF; 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane; blend-PI; blend-po
Lovastatin suppresses the aberrant tau phosphorylation from FTDP-17 mutation and okadaic acid-induction in rat primary neurons
Keywords: AAV; adeno-associated virus; ACAT; acyl-CoA:cholesterol acyltransferase; AD; Alzheimer's disease; CDK; cyclin-dependent kinase; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FTDP-17; frontotemporal dementia and Parkinson
Chylomicron remnant model emulsions induce intracellular cholesterol accumulation and cell death due to lysosomal destabilization
Keywords: ACAT; acyl CoA:cholesterol acyltransferase; ac-LDL; acetylated LDL; apoE; apolipoprotein E; BSA; bovine serum albumin; CE; esterified cholesterol; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; HSPGs; heparan
Parameterization of small intestinal water volume using PBPK modeling
Keywords: PBPK; physiologically-based pharmacokinetic; FDA; US Food and Drug Administration; ACAT; advanced compartmental absorption and transit; ADAM; advanced dissolution, absorption, and metabolism; CAT; compartmental absorption and transit; SIWV; small intestin
Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities
Keywords: ACAT; acyl CoA:cholesterol acyltransferase; ADME; absorption, distribution, metabolism and excretion; APCI; atomospheric pressure chemical ionization; CM; chylomicron; dba; dibenzylideneacetone; CYP; cytochrome P450; DDI; drug-drug interaction; DGAT; ac
Areca catechu L. (Arecaceae): A review of its traditional uses, botany, phytochemistry, pharmacology and toxicology
Keywords: AA; arachidonic acid; ACAT; acyl coenzyme A-cholesterol acyltransferase; ACE; angiotensin-converting enzyme; ACEAN; ethyl acetate extracts of areca nut; AchE; acetylcholinesterase; AchR; acetylcholine receptors; ADP; adenosine diphosphate; AEAN; acetone e