Keywords: ACC1; acetylcoenzyme A carboxylase 1; ASIP; agouti signaling protein; BETA2; transcription factor Beta 2; CYP7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cFOS; transcription factor C-fos; FASN; fatty acid synthase; FOXA2; forkhead box prote
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Keywords: GDM; gestational diabetes mellitus; T2D; type 2 diabetes; CVD; cardiovascular disease; DOHaD; developmental origins of health and disease; CDA; Canadian diabetes association; HOMA-IR; homeostatic model assessment for insulin resistance; DINT; dietary inte
Keywords: ACC1; acetyl-CoA carboxylase 1; AHCY; S-adenosylhomocysteine hydrolase; AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; BHMT; betaine homocysteine methyltransferase; CD36; fatty acid translocase; CPT1α; carnitine palmitoyltransfera
Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Keywords: 27-HC; 27-Hydroxycholesterol; 3PO; 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; ABCG1; ATP-binding cassette subfamily G1; ACBA1; ATP-binding cassette subfamily A1; ACC1; Acetyl-Co-A carboxylase-1; AKAP4; A-kinase anchoring protein 4; ALDO; Aldolase; AM
Keywords: Acc1; acetyl coenzyme A carboxylase alpha; Cer; ceramide; Elovl5 and Elovl6; fatty acid elongase 5 and 6; Fads1 and Fads2; fatty acid desaturase 1 and 2; DHA; docosahexaenoic acid; DHP; dihydroprogesterone; Fas; fatty acid synthase; GalCer; C17 mono-sulfo
Keywords: BMI; Body mass index; T2DM; Type 2 diabetes mellitus; MHO; Metabolically healthy but obese; MUHNW; Metabolically unhealthy normal weight; MUHO; Metabolically unhealthy obese; MAO; Metabolically abnormal obese; LDL; Low density lipoprotein; HDL; High densi
Keywords: AcCoA carboxylase; Cancer cell metabolism; α-Ketoacid dehydrogenase; Warburg effect; Acc1; AcCoA carboxylase; FAS; fatty acid synthase complex; KGDC; pyruvate dehydrogenase complex; PDC; pyruvate dehydrogenase complex; OADC; oxaloacetate dehydrogenase co
Keywords: 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; ABA; activity-based anorexia; ACC1; acetyl coenzyme-A carboxylase-1; AEA; N-arachidonoylethanolamine; AN; anorexia nervosa; ARC; arcuate nucleus; BBB; blood-brain barrier; BED; binge eating disorder; BN;
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice
Keywords: A-type procyanidins; Oxidative stress; Glucose homeostasis; Type 2 diabetes; mTOR; ACC1; acetyl coenzyme A carboxylase 1; ACL; ATP-citrate lyase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under curve; BAT; brown adipose tis
Gangjihwan, a polyherbal composition, inhibits fat accumulation through the modulation of lipogenic transcription factors SREBP1C, PPARγ and C/EBPα
Keywords: ACC1; acetyl-CoA carboxylase 1; C/EBPα; CCAAT/enhancer binding protein alpha; DF; Gangjihwan; DEG; differentially expressed gene; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethylsulfoxide; FAS; fatty acid synthase; HPLC; high performance liquid chr
Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice
Keywords: 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)
Safety and efficacy of Melissa officinalis (lemon balm) on ApoA-I, Apo B, lipid ratio and ICAM-1 in type 2 diabetes patients: A randomized, double-blinded clinical trial
Keywords: ACC1; Acetyl-CoA carboxylase 1; AMPK/ACC; AMP-activated protein kinase/Acetyl-CoA c arboxylase; ALP; alkaline phosphatase; ALT; alanine aminotransferase; ANCOVA; analysis of covariance; Apo-B; apolipoprotein B; Apo A-I; apolipoprotein A-I; AST; aspartate
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways
Keywords: Arctigenin; Lipotoxicity; Steatosis; Inflammation; Nonalcoholic fatty liver disease; ACC1; acetylcoenzyme A carboxylase 1; ACO; acyl-CoA oxidase; ATG; arctigenin; CPT-1; carnitine palmitoyltransferase 1; FAS; fatty acid synthase; MDA; malondialdehyde; NAF
The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica inhibits hepatic steatosis and fibroinflammtion in high-fat diet-induced obese mice
Keywords: α-SMA; α-smooth muscle actin; ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; AST; aspartate transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; ECM; extracellular m
Human-based systems: Mechanistic NASH modelling just around the corner?
Keywords: Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a
Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c
Keywords: ACC1; acetyl CoA carboxylase 1; CRP; C reactive protein; FAS; fatty acid synthase; H2O2; hydrogen peroxide; HFD; high fat diet; IL-1β; interleukin-1; IPGTT; intraperitoneal glucose tolerance test; IPITT; intraperitoneal insulin tolerance test; KuA; Kukoa
Cassia auriculata flower extract attenuates hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol metabolism
Keywords: Et- CAF; ethanolic extract of Cassia auriculata flower; HMGR; HMG-CoA reductase; HMGS; HMGCoA synthase; SREBP-1c; sterol regulatory element binding protein -1c; SREBP-2; sterol regulatory element binding protein- 2; CYP7A1; cholesterol 7 α-hydroxylase; A
Role of salt inducible kinase 1 in high glucose-induced lipid accumulation in HepG2 cells and metformin intervention
Keywords: SIK1; High glucose; Lipogenesis; SREBP-1c; FASN; ACC1; Metformin; HepG2 cells;
Defining the Na+/H+ exchanger NHE1 interactome in triple-negative breast cancer cells
Keywords: ACC1; acetyl-CoA carboxylase; AKT; protein kinase B, PKB; CAII; carbonic anhydrase II; CHP1; calcineurin B homologous protein 1; ER; estrogen receptor; ERK1/2; extracellular signal-regulated kinase 1/2; ERM; ezrin-radixin-moesin; FOXO3a; forkhead box O3a;
Antidiabetic activity of Ganoderma lucidum polysaccharides F31 down-regulated hepatic glucose regulatory enzymes in diabetic mice
Keywords: ACC1; acetyl-CoA carboxylase 1; AMPK; AMP-activated protein kinase; BW; body weight; DM; diabetes mellitus; ELISA; enzyme-linked immunosorbent assay; FAS; fatty acidy synthase; FBPase; fructose-1,6-bisphosphatase; FSG; fasting serum glucose; FSI; fasting
Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice
Keywords: ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; DF; Gangjihwan; FAS; fatty acid synthase; HE; hematoxylin-eosin; HFD; high fat di
Heat-killed Bifidobacterium animalis subsp. Lactis CECT 8145 increases lean mass and ameliorates metabolic syndrome in cafeteria-fed obese rats
Keywords: Acc1; acetyl CoA carboxylase 1; Agrp; agouti-related protein; ANOVA; analysis of variance; Atgl; adipose triacylglycerol lipase; β-actin; actin beta; Ba8145; Bifidobacterium animalis subsp. lactis strain CECT 8145; Cart; cocaine and amphetamine-regulated
Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance
Keywords: StAR; steroidogenic acute regulatory protein; NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered solution; FBS; fetal bovine serum; ITS-X; insulin-transferrin-selenium-ethanolamine
High-Fructose Intake Impairs the Hepatic Hypolipidemic Effects of a High-Fat Fish-Oil Diet in C57BL/6 Mice
Keywords: ACC1; acetyl-CoA carboxylase-1; CPT1a; carnitine palmitoyltransferase 1a; ChREBP; carbohydrate response element binding protein; FASN; fatty acid synthase; FFA; free fatty acid; LPL; lipoprotein lipase; LXRα; liver-X-receptor; MTTP; microsomal triglyceri
Prunus mume Sieb. et Zucc. fruit ameliorates alcoholic liver injury in mice by inhibiting apoptosis and inflammation through oxidative stress
Keywords: Prunus mume Sieb. et Zucc; Alcoholic liver injury; Hepatic apoptosis; Lipogenesis; Natural antioxidant; 4-HNE; 4-hydroxynonenal; ACC1; acetyl coenzyme A carboxylase 1; CGA; chlorogenic acid; CMFDA; 5-chloromethylfluorescein diacetate; DAPI; 4',6-diamidino
The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells
Keywords: AMPK; adenosine monophosphate-activated protein kinase; ACC1; acetyl CoA carboxylase 1; Bp4eT; 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone; BpT; 2-benzoylpyridine thiosemicarbazone; CaMKKβ; calmodulin-mediated kinase kinase β; DFO; desferrioxamine; Dp
Zinc triggers signaling mechanisms and defense responses promoting resistance to Alternaria brassicicola in Arabidopsis thaliana
Keywords: AbACT; Alternaria brassicicola actin gene; ACC1; aminocyclopropane-1-carboxylic acid; AcOH; acetic acid; BGL2; β-1,3-glucanase 2, pathogenesis-related protein 2; CDS; copper superoxide dismutase; CHIB; basic chitinase, pathogenesis-related protein 3; Col
Interactions between dietary protein levels, growth performance, feed utilization, gene expression and metabolic products in juvenile grass carp (Ctenopharyngodon idella)
Keywords: NPY; neuropeptide Y; ACC1; acetyl-CoA carboxylase 1; UCP1; uncoupling protein 1; PPARγ; peroxisome proliferator-activated receptor γ; PWG; percent weight gain; FCR; feed conversion ratio; AST; aspartate aminotransferase; ALT; alanine transaminase; TG; t
Betahistine co-treatment ameliorates dyslipidemia induced by chronic olanzapine treatment in rats through modulation of hepatic AMPKα-SREBP-1 and PPARα-dependent pathways
Keywords: ACC1; acetyl-CoA carboxylase 1; AMPKα; AMP-activated protein kinaseα; CPT1A; carnitine palmitoyltransferase 1A; FASN; fatty acid synthetase; H1R; histamine H1 receptors; H3R; histamine H3 receptors; HDL-C; high density lipoprotein cholesterol; HMGCoA; 3
Changes of Saccharomyces cerevisiae cell membrane components and promotion to ethanol tolerance during the bioethanol fermentation
Keywords: Saccharomyces cerevisiae; Bioethanol fermentation process; Cell membrane; Ethanol tolerance; Gene expression; ACC1; Acetyl-CoA carboxylase; HFA1; Acetyl-CoA carboxylase; OLE1; stearoyl-CoA 9-desaturase; ACT1; β-actin; GC; gas chromatography; LC; liquid c
Improving polyketide and fatty acid synthesis by engineering of the yeast acetyl-CoA carboxylase
Keywords: Saccharomyces cerevisiae; Acc1; Phosphorylation; 6-MSA; Polyketides; Fatty acids
Compared to fish oil alone, a corn and fish oil mixture decreases the lipid requirement of a freshwater fish species, Carassius auratus gibelio
Keywords: â³6Fad; Î6 fatty acid desaturase; ACC1; acetyl-CoA carboxylase alpha; Elovl5; fatty acyl elongase 5; FAS; fatty acid synthase; LC-PUFAs; highly unsaturated fatty acids; MUFAs; monounsaturated fatty acids; PUFAs; polyunsaturated fatty acids; SFAs; satura
The local corticotropin-releasing hormone receptor 2 signalling pathway partly mediates hypoxia-induced increases in lipolysis via the cAMP-protein kinase A signalling pathway in white adipose tissue
Keywords: Hypoxia; Corticotropin-releasing hormone receptor 2; White adipose tissue; Lipolysis; CRHR2; corticotrophin-releasing hormone receptor type 2; Ucn2; urocortin 2; Ucn3; urocortin 3; WAT; white adipose tissue; BAT; brown adipose tissue; PKA; protein kinase
FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice
Keywords: MKP-3; MAP kinase phosphatase 3; Dex; Dexamethasone; FOXO1; forkhead box protein O1; GC; glucocorticoid; DUSP6; dual specificity protein phosphatase 6; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphoinosit
Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells
Keywords: ACC1; acetyl CoA-carboxylase; ALA; α-linolenic acid; BSA; bovine serum albumin; ChREBP; carbohydrate response element binding protein; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; HC; high-carbohydrate; HF; high fat; LE; lipid emulsion; LA; lin
Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH)
Keywords: ATGL; adipose triglyceride lipase; ACC1; acetyl-CoA carboxylase; ACSL1; long-chain fatty-acid-coenzyme A ligase; ap2/FABP4; adipocyte protein 2/fatty acid binding protein 4; ATP5B; ATP synthase, HÂ + transporting mitochondrial F1 complex, beta subunit; BA
Phylogenetic relationships and Y genome origin in Elymus L. sensu lato (Triticeae; Poaceae) based on single-copy nuclear Acc1 and Pgk1 gene sequences
Keywords: Phylogenetic relationships; Genome origin; Elymus L. sensu lato; Acc1; Pgk1;
MicroRNA-1 and microRNA-206 suppress LXRα-induced lipogenesis in hepatocytes
Keywords: LXRα/β; Liver X receptor α/β; miRs; MicroRNAs; SREBP-1c; sterol-regulatory element binding protein 1c; FAS; fatty acid synthase; ChREBP; carbohydrate responsive element-binding protein; ACC1; acetyl-CoA carboxylase 1; RXRα; retinoid X receptor α; LX
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis
Keywords: ACC1; acetyl-CoA carboxylase 1; SAMe; S-adenosylmethionine; AMPK; AMP-activated protein kinase; HNE; 4-hydroxy-2-nonenal; ANT; adenine nucleotide translocator; NRTI; antiretroviral nucleoside analog; ChREBP; carbohydrate responsive element-binding protein
Intermittent MTII application evokes repeated anorexia and robust fat and weight loss
Keywords: Melanocortin activation; MTII; ACC1; Fatty acid synthesis; Tachyphylaxis
Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2
Keywords: Acetyl-CoA carboxylase; ACC; Enzyme inhibitor; Spirochromanone; ACC1; ACC2; Structure based drug discovery; Diabetes; Metabolic syndrome
Research ArticleAmelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22
Keywords: aa; amino acid; ACC1; acetyl-CoA carboxylase; ACLY; ATP citrate lyase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ChREBP; MLX interacting protein-like; CYP7A1; cytochrome P450, family 7, subfamily a, polypeptide 1; DGAT1/2; diacylglyc
Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes
Keywords: ACC1; Lipogenesis; Isozyme; Human; Ovine; Mouse; Brain; Adipose tissue; Bidirectional promoters; Histone acetylation; SAGA-type complexes; FLJ39647;