دانلود مقالات ISI درباره مواد اولیه دارویی فعال + ترجمه فارسی

Investigation of inclusion behaviour of gefitinib with epichlorohydrin-β-cyclodextrin polymer: preparation of binary complex, stoichiometric determination and characterization

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; ATP; adenosine tri phosphate; BCS; biopharmaceutical classification system; DSC; differential scanning calorimetry; DTA; differential thermal analysis; EGFR; epidermal growth factor receptor; Epi-β-CD; polymerized e

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

InVitro Evaluation of Optimal Inhalation Flow Patterns for Commercial Dry Powder Inhalers and Pressurized Metered Dose Inhalers With Human Inhalation Flow Pattern Simulator

Keywords: مواد اولیه دارویی فعال; inhalation flow pattern; dry powder inhalers; pressurized metered dose inhalers; inhalation performance; ACI; Andersen cascade impactor; API; active pharmaceutical ingredient; DPIs; dry powder inhalers; FIR; flow increase rate; FPF; fine particle fraction

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32

Keywords: مواد اولیه دارویی فعال; Allergy; grass pollen allergy; allergen; allergen immunotherapy; recombinant allergen; B-cell epitope-based immunotherapy; efficacy; hypoallergenic; clinical trial; safety; AE; Adverse event; AIT; Allergen immunotherapy; API; Active pharmaceutical ingre

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Impurity profiling of varenicline tartrate by LC-QTOF mass spectrometric techniques during drug development

Keywords: مواد اولیه دارویی فعال; VRC; varenicline; API; active pharmaceutical ingredient; RSs; related substances; nAChR; nicotinic acetylcholine receptor; FDA; Food and Drug Administration; Varenicline tartrate; Related substancesRelated substances; LC-QTOF-MS;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Cloning, expression and characterisation of P450-Hal1 (CYP116B62) from Halomonas sp. NCIMB 172: A self-sufficient P450 with high expression and diverse substrate scope

Keywords: مواد اولیه دارویی فعال; ALA; Aminolevulinic acid; API; Active pharmaceutical ingredient; BM3; CYP102A1 from Bacillus megaterium; FAD; Flavin adenine dinucleotide; FMN; Flavin mononucleotide; GDH; Glucose dehydrogenase; Hal1; CYP116B62 from Halomonas sp. NCIMB 172; HalC; CYP116B4

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Fast and non-destructive determination of active pharmaceutical ingredient concentration in an electrospun nanofiber patch using infrared spectroscopy

Keywords: مواد اولیه دارویی فعال; α-Arbutin; Electrospun-nanofiber patches; Active pharmaceutical ingredient; Non-destructive measurement; Transmission IR spectroscopy;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Investigation of the distributional homogeneity on chlorpheniramine maleate tablets using NIR-CI

Keywords: مواد اولیه دارویی فعال; DHI; Distributional Homogeneity Index; CPM; chlorpheniramine maleate; NIR-CI; near infrared chemical imaging; PAT; process analysis technology; CQAs; critical quality attributes; API; active pharmaceutical ingredient; HPLC; high-performance liquid chromat

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Performance indicators for carrier-based DPIs: Carrier surface properties for capsule filling and API properties for in vitro aerosolisation

Keywords: مواد اولیه دارویی فعال; AE; aeration energy; AIF; angle of internal friction; API; active pharmaceutical ingredient; APSD; aerodynamic particle-size distribution; BD; bulk density; BFE; basic flow energy; CI; Carr's index; COPD; chronical obstructive pulmonary disease; CPH; ca

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Octenylsuccinate hydroxypropyl phytoglycogen, a dendrimer-like biopolymer, solubilizes poorly water-soluble active pharmaceutical ingredients

Keywords: مواد اولیه دارویی فعال; Octenylsuccinate hydroxypropyl phytoglycogen; Solubilization; Solid dispersion; Active pharmaceutical ingredient;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Assessment of Tapentadol API Abuse Liability With the Researched Abuse, Diversion and Addiction-Related Surveillance System

Keywords: مواد اولیه دارویی فعال; Prescription drug abuse; prescription opioid abuse; prescription opioid analgesic; tapentadol abuse liability; active pharmaceutical ingredient; human; pain management;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Efficiency of extraction and conversion of pseudoephedrine to methamphetamine from tamper-resistant and non-tamper-resistant formulations

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; BTC; behind-the-counter; CMEA; Combat Methamphetamine Epidemic Act; CMP; 1-(1′4′-cyclohexadienyl)-2-methylaminopropane; DEA; Drug Enforcement Administration; FDA; Food and Drug Administration; HCl; hydrochloride;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

UV imaging in pharmaceutical analysis

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; ATR-FTIR; attenuated reflectance-Fourier transform infrared; CARS; coherent anti-Stokes Raman Scattering Microscopy; CMOS; Complementary metal oxide semiconductor; EMMA; electrophoretically mediated micro-analysis; L

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs

Keywords: مواد اولیه دارویی فعال; AME; absorption-modifying excipient; API; active pharmaceutical ingredient; BCS; biopharmaceutics classification system; BE; bioequivalence; CL; clearance; CPE; critical pharmaceutical excipient; Ffirstpass; firstpass extraction; GI; gastrointestinal; Pap

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of chirality on the Glass Forming Ability and the crystallization from the amorphous state of 5-ethyl-5-methylhydantoin, a chiral poor glass former

Keywords: مواد اولیه دارویی فعال; 5-Ethyl-5-methylhydantoin (PubChem CID: 82,162); API; Active Pharmaceutical Ingredient; GFA; Glass Forming Ability; FSC; Fast Scanning Calorimetry; DSC; Differential Scanning Calorimetry; BCS; BioPharmaceutical Classification System; ee; Enantiomeric Exce

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

High-performance liquid chromatography coupled to inductively coupled plasma - Mass spectrometry (HPLC-ICP-MS) for quantitative metabolite profiling of non-metal drugs

Keywords: مواد اولیه دارویی فعال; Quantitative drug metabolite profiling; Inductively coupled plasma - (tandem) mass spectrometry coupled to high-performance liquid chromatography; Spectral interference; Chemical resolution; Chemical derivatization for ICP-MS detection; ICP-MS(/MS); ind

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Development of TCM-based composite particles for direct compaction by particle design

Keywords: مواد اولیه دارویی فعال; Direct compaction; Design of experiment; Compactibility; Flowability; Yield; Traditional Chinese medicine; AHE; Andrographis herba extract; API; active pharmaceutical ingredient; AR; angle of repose; AUTCC; area under the tensile strength versus compactio

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Investigating the effects of amphipathic gastrointestinal compounds on the solution behaviour of salt and free base forms of clofazimine: An in vitro evaluation

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; AUC; area under the curve; BCS; biopharmaceutics classification system; CFZ; clofazimine; CFZB; clofazimine free base; CFZHCl; clofazimine hydrochloride; CMC; critical micelle concentration; FaSSGF; fasted state simu

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Dual mechanism of microenvironmental pH modulation and foam melt extrusion to enhance performance of HPMCAS based amorphous solid dispersion

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; ASD; amorphous solid dispersion; HME; Hot-melt extrusion; HPMCAS; Hydroxypropyl methylcellulose acetate succinate; PAT; Process Analytical Technology; QbD; Quality by Design; Foam melt extrusion; Amorphous solid disp

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Dry powder inhalers: An overview of the in vitro dissolution methodologies and their correlation with the biopharmaceutical aspects of the drug products

Keywords: مواد اولیه دارویی فعال; Pulmonary delivery; Dry powder inhalation; Solubility; Dissolution methods; Biopharmaceutical classification; API; Active pharmaceutical ingredient; ACI; Andersen cascade impactor; ALF; alveolar lung fluid; BCS; Biopharmaceutics Classification System; iBC

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Ability of gelatin and BSA to stabilize the supersaturated state of poorly soluble drugs

Keywords: مواد اولیه دارویی فعال; Solubility; Supersaturation; Protein; Gelatin; bovine serum albumin (BSA); Biopolymers; API; Active Pharmaceutical Ingredient; ASD; amorphous Solid Dispersion(s); AUC; Area Under the Curve; BCS; Biopharmaceutics Classification System; BSA; Bovine Serum Al

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Use of biorelevant dissolution and PBPK modeling to predict oral drug absorption

Keywords: مواد اولیه دارویی فعال; Biorelevant dissolution; Weak base; PBPK modeling; BCS class II; pH dependent solubility; ACAT; advanced compartmental absorption and transit model; ADAM; advanced dissolution, absorption and metabolism model; API; active pharmaceutical ingredient; ASD;

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

Variable-focus microscopy and UV surface dissolution imaging as complementary techniques in intrinsic dissolution rate determination

Keywords: مواد اولیه دارویی فعال; IBU; ibuprofen; USP; United Sates Pharmacopeia; SDS; sodium dodecyl sulphate; DSC; differential scanning calorimetry; XRPD; x-ray powder diffraction; IDR; intrinsic dissolution rate; SDI; surface dissolution imaging; API; active pharmaceutical ingredient;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of polymer type on the surface energy of acetaminophen solid dispersions prepared by melt method

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; IGC; inverse gas chromatography; K12; Kollidon® 12 PF; K64; Kollidon® VA 64; PM; physical mixture; SD; solid dispersion; Sol; Soluplus®; STD; standard deviation; Surface energy; Solid dispersion; Physical mixture;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Mimicking the Impact of Infant Tongue Peristalsis on Behavior of Solid Oral Dosage Forms Administered During Breastfeeding

Keywords: مواد اولیه دارویی فعال; in vitro models; oral drug delivery; pediatric; physical characterization; drug delivery systems; API; active pharmaceutical ingredient; NSDS; nipple shield delivery system; PEEK; polyetheretherketone; SB; sulforhodamine B; TM; tongue mimic; TMS; tongue

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Development of an abiraterone acetate formulation with improved oral bioavailability guided by absorption modeling based on in vitro dissolution and permeability measurements

Keywords: مواد اولیه دارویی فعال; AA; abiraterone acetate; API; active pharmaceutical ingredient; FaSSIF/FeSSIF; fasted/fed state simulated intestinal fluid; PAMPA; parallel artificial membrane permeation assay; S.D.; standard deviation; HPLC; high performance liquid chromatography; DLS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of the pulmonary deposition and in vitro permeability on the prediction of plasma levels of inhaled budesonide formulation

Keywords: مواد اولیه دارویی فعال; ACAT; advanced compartmental absorption and transit; ADRM; additional dosage route module; ALE; air-liquid interface exposure; API; active pharmaceutical ingredient; APSD; aerodynamic particle size distribution; AUC; area under the curve; CF; cystic fibro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule

Keywords: مواد اولیه دارویی فعال; ACN; acetonitrile; API; active pharmaceutical ingredient; ASD; amorphous solid dispersions; AUC; area under the curve; BCS; biopharmaceutics classification system; CD; cyclodextrin; Cmax; maximum concentration; DSC; differential scanning calorimetry; FA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperNovel concentrated water-in-oil emulsions based on a non-ionic silicone surfactant: Appealing application properties and tuneable viscoelasticity

Keywords: مواد اولیه دارویی فعال; O/W; oil-in-water; W/O; water-in-oil; API; active pharmaceutical ingredient; SC; stratum corneum; ATR; attenuated total reflection; FTIR; Fourier transform infrared spectroscopy; Water-in-oil emulsion; Silicone surfactant; Skin-friendly; Skin permeation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Changing paradigms in bioequivalence trials submitted to the EMA for evaluation - A clinical and regulatory perspective

Keywords: مواد اولیه دارویی فعال; EU; European Union; MA; marketing authorisation; BE; bioequivalence; BCS; Biopharmaceutics Classification System (BCS); CHMP; Committee for Medicinal Products for Human Use; NHS; National Health System; API; active pharmaceutical ingredient; EMA; European

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of highly branched cyclic dextrin in inhalable particles of combined antibiotics for the pulmonary delivery of anti-tuberculosis drugs

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; βCD; β-cyclodextrin; BET; Brunauer-Emmett-Teller; DPI; dry powder-inhaler; ED; emitted dose; FPD; fine-particle dose; FPF; fine-particle fraction; HBCD; highly branched cyclic dextrin; HPLC; high performance li

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperElectrospraying of polymer solutions: Study of formulation and process parameters

Keywords: مواد اولیه دارویی فعال; Microparticles; Nanoparticles; Electrospraying; Polymer solutions; Cone-jet mode; Solid dispersion; API; active pharmaceutical ingredient; BCS; Biopharmaceutics Classification System; HPMC; hydroxypropyl methylcellulose; HPMCP; hydroxypropyl methylcellulo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperThe dispersion releaser technology is an effective method for testing drug release from nanosized drug carriers

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; BSA; bovine serum albumin; CAR; compartmental accumulation ratio; DB; dialysis bag; DLS; dynamic light scattering; DR; dispersion releaser; FDA; Food and Drug Administration; HPLC; high-performance liquid chromatogra

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluating the predictability of the in vitro transfer model and in vivo rat studies as a surrogate to investigate the supersaturation and precipitation behaviour of different Albendazole formulations for humans

Keywords: مواد اولیه دارویی فعال; ABZ; Albendazole; HPβCD; hydroxypropyl-β-cyclodextrin; HPMC; hydroxypropylmethylcellulose; GIT; gastro intestinal tract; PK; pharmacokinetic; API; active pharmaceutical ingredient; rpm; rounds per minute; FaSSGF; fasted state simulating gastric fluid; F

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of different in vitro dissolution tests based on level A in vitro-in vivo correlations for fenofibrate self-emulsifying lipid-based formulations

Keywords: مواد اولیه دارویی فعال; Af; absorbed API fraction without EHC; API; Active Pharmaceutical Ingredient; AUC; Area Under the Curve; BCS; Biopharmaceutics Classification System; Cmax; Maximal Concentration; CS; Saturation Concentration; DSC; Differential Scanning Calorimetry; EHC; E

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast

Keywords: مواد اولیه دارویی فعال; ADMET; absorption, distribution, metabolism, excretion, and toxicity; API; active pharmaceutical ingredient; CPR; NADPH-cytochrome P450 oxidoreductase; CYP; cytochrome P450; EMM; Edinburgh Minimal Medium; HLMs; human liver microsomes; RLU; relative lumine

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

The SeDeM Expert Diagram System: Its performance and predictability in direct compressible formulations containing novel excipients and different types of active ingredients

Keywords: مواد اولیه دارویی فعال; % < 50; Particle size; %H; Hygroscopicity; %HR; Loss on drying; API; Active pharmaceutical ingredient; Carr; Carr's index; Coh; Cohesion index; Da; Bulk density; Dc; Tapped density; Haus; Hausner ratio; Ie; Inter-particle porosity; Iθ; Homogeneity inde

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Photostability testing using online reactor HPLC hyphenation and mass spectrometric compound identification illustrated by ketoprofen as model compound

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; DAD; diode array detection; EI; electron ionization; ESI; electrospray ionization; ESI+; positive electrospray ionization; FDA; US Food and Drug Administration; GC; gas chromatography; HPLC; high performance liquid c

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Efavirenz dissolution enhancement III: Colloid milling, pharmacokinetics and electronic tongue evaluation

Keywords: مواد اولیه دارویی فعال; EFV; efavirenz; NNRTI; non-nucleoside reverse transcriptase inhibitor; HIV-1/AIDS; human immunodeficiency virus type 1 infection; SLS; sodium lauryl sulfate; HPC; hydroxypropylcellulose; HPMC; hydroxypropylmetilcellulose; NRTIs; nucleoside reverse transcr

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

An innovative method for the preparation of high API-loaded hollow spherical granules for use in controlled-release formulation

Keywords: مواد اولیه دارویی فعال; Granulation; High shear mixer; High active pharmaceutical ingredient-loaded granule; Hollow spherical particle; Controlled release; Low cost; API; active pharmaceutical ingredient; CR; controlled released; PSD; particle size distribution; SEM; scanning el

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewAdvances in drug delivery systems based on synthetic poly(hydroxybutyrate) (co)polymers

Keywords: مواد اولیه دارویی فعال; AG; A33scFv green fluorescence protein; 3HB-CoA; 3-hydroxybutyryl-coenzyme A; API; active pharmaceutical ingredient; ATRP; atom transfer radical polymerization; BL; β-butyrolactone; BLallyl; allyl-β-butyrolactone; rac-BL; racemic β-butyrolactone; rac-B

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmaceutical salts of ethionamide with GRAS counter ion donors to enhance the solubility

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; ETH; ethionamide; CNB; 2-chloro-4-nitrobenzoic acid; 2,6HBA; 2,6-dihydroxybenzoic acid; 2,3HBA; 2,3-dihydroxybenzoic acid; DNB; 2,4-dinitrobenzoic acid; SCXRD; single crystal x-ray diffraction; PXRD; powder X-ray dif

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques

Keywords: مواد اولیه دارویی فعال; Drug; Active pharmaceutical ingredient; Crystallographic studies; Spectroscopic characterization; Thermal analysis; NMR crystallography; Solubility; Stability;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies

Keywords: مواد اولیه دارویی فعال; 4-Aminosalicylic acid (PubChem CID: 4649); Pyrazinamide (PubChem CID: 1046); Nicotinamide (PubChem CID: 936); Isonicotinamide (PubChem CID: 15074); Isoniazid (PubChem CID: 3767); Caffeine (PubChem CID: 2519); Theophylline (PubChem CID: 2153); Methanol (Pu

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Keywords: مواد اولیه دارویی فعال; API; active pharmaceutical ingredient; AUC; area under the curve; BCS; biopharmaceutics classification system; BP; blood-to-plasma ratio; Cmax; maximum concentration; CL; clearance; Do; dose number according to BCS; DDI; drug-drug interaction; EFPIA; Euro

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Keywords: مواد اولیه دارویی فعال; AFE; Average Fold Error; AAFE; Absolute Average Fold Error; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CCC; Concordance Correlation Coeffici

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Keywords: مواد اولیه دارویی فعال; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CL; Clearance; CL/F; Apparent clearance; Cmax; Maximum concentration; Do; Dose number; fa; Fracti

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Precipitation of curcumin by pressure reduction of CO2-expanded acetone

Keywords: مواد اولیه دارویی فعال; Pressure reduction; Subcritical CO2; Curcumin; Precipitation; Polymorphism; Active pharmaceutical ingredient;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Development of a Predictive Model for the Stabilizer Concentration Estimation in Microreservoir Transdermal Drug Delivery Systems Using Lipophilic Pressure-Sensitive Adhesives as Matrix/Carrier

Keywords: مواد اولیه دارویی فعال; polymeric drug delivery system; transdermal; solid dispersion; amorphous; physical stability; thermal analysis; hydration; water sorption; thermodynamics; mathematical model; a; activity; API; active pharmaceutical ingredient; ASA; acetylsalicylic acid; D

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Impact of sodium chloride on the expansion of a liquid-liquid miscibility gap in an API/water system. Case study of Brivaracetam

Keywords: مواد اولیه دارویی فعال; BRV; brivaracetam or UCB34714; DITA; discontinuous isoperibolic thermal analysis; IV; intravenous; API; active pharmaceutical ingredient; Brivaracetam (PubChem CID: 9837243); Brivaracetam; Liquid-liquid miscibility gap; Phase diagrams; IV administration;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of phosphodiesterase type V inhibitors in wastewater by direct injection followed by liquid chromatography coupled to tandem mass spectrometry

Keywords: مواد اولیه دارویی فعال; PDE5; phosphodiesterase type V; ED; erectile dysfunction; API; active pharmaceutical ingredient; WWTP; wastewater treatment plant; ILIS; isotopically labeled internal standard; WBE; wastewater-based epidemiology; Wastewater-based epidemiology; Phosphodies

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه