دانلود مقالات ISI درباره ADAM، disintegrin و متالوپروتئیناز + ترجمه فارسی

In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, ADAM with thrombospondin domains motifs; ECM, extracellular matrix; LAP, latency-associated protein; LGAL, amarckian genetic algorithm; Kd, dissociation constant; MD, molecular dynamics; RMSD, root mean s

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation

Keywords: ADAM، disintegrin و متالوپروتئیناز; UC, ulcerative colitis; ADAM, a disintegrin and metalloproteinase; TNF, tumor necrosis factor; EGFR, epidermal growth factor receptor; MMP, matrix metalloproteinase; EGF, epidermal growth factor; TACE, tumor necrosis factor-α converting enzyme; IBD, infla

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, A Disintegrin And Metalloproteinase; BACE, β-site APP cleaving enzyme; APP, amyloid precursor protein; AD, Alzheimer disease; RIP, regulated intramembrane proteolysis; PC, prohormone convertase; CNS, central nervous system; UTR, untranslated region;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Common variable immunodeficiency and autoimmunity – an inconvenient truth

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; AHA, autoimmune hemolytic anemia; AID, activation induced cytidine deaminase; ALT, alanine aminotransferase; AMA, antimitochondrial antibody; ANA, antinuclear antibody; AST, aspartate aminotransferase; BAFF-R, B

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Epiregulin: Roles in normal physiology and cancer

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, A disintegrin and metalloproteinase; B[a]P, benzo[a]pyrene; CASMC, coronary artery smooth muscle cell; COPD, chronic obstructive pulmonary disease; COX-2, cyclooxygenase 2; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; FLS, f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Differential protein–protein interactions of full length human FasL and FasL fragments generated by proteolysis

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; (F-)BAR, (Fer/CIP4 homology-)Bin–Amphiphysin–Rvs; ESCRT, endosomal sorting complexes required for transport; FasL, Fas ligand; ICD, intracellular domain; I-CLiP, intramembrane-cleaving protease; mab, monoclonal a

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Carnosic acid suppresses the production of amyloid-β 1–42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells

Keywords: ADAM، disintegrin و متالوپروتئیناز; Aβ, amyloid-β; AD, Alzheimer's disease; ADAM, a disintegrin and metalloproteinase; APP, amyloid precursor protein; BACE1, β-site APP-cleaving enzyme-1; BCA, bicinchoninic acid; BSA, bovine serum albumin; CA, carnosic acid; CHAPS, 3-[(3-Cholamidopropyl)dim

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Colon tumour secretopeptidome: Insights into endogenous proteolytic cleavage events in the colon tumour microenvironment

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; APP, amyloid precursor protein; BSG, basigin; CALR, calreticulin; CDH1, epithelial cadherin; CEA, carcinoembryonic antigen; CM, culture medium; CRC, colorectal cancer; CTF, carboxy-terminal fragment; DG, dystrogl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

CD46: The ‘multitasker’ of complement proteins

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; AP-1, activator protein 1; aHUS, atypical hemolytic uremic syndrome; AMD, age-related macular degeneration; Bcl-2, B-cell lymphoma 2; CCL, chemokine (C-C motif) ligand; CCP, complement control protein domain; CSL

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Lost in disruption: Role of proteases in glioma invasion and progression

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, ADAMs with thrombospondin motifs; bFGF, basic fibroblast growth factor; ECM, extracellular matrix; EGF, epidermal growth factor; FAP, fibroblast activation protein; GAG, glycosaminoglycan; GFAP, glial fib

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Distinct role of matrix metalloproteinase-3 in kidney injury molecule-1 shedding by kidney proximal tubular epithelial cells

Keywords: ADAM، disintegrin و متالوپروتئیناز; ACT-D, actinomycin D; ADAM, a disintegrin and metalloproteinase; APMA, aminophenylmercuric acetate; BB-2516, marimastat; BB-94, batimastat; DAPI, 4′,6′-diamidino-2-phenylindole hydrochloride; DMSO, dimethyl sulfoxide; DPI, diphenylene iodonium; FBS, fetal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Preventing cleavage of Mer promotes efferocytosis and suppresses acute lung injury in bleomycin treated mice

Keywords: ADAM، disintegrin و متالوپروتئیناز; Mer, Mer receptor tyrosine kinase; ADAM, a disintegrin and metalloproteinase; TAM, Tyro-3/Axl/Mer; Gas6, growth arrest-specific protein 6; LPS, lipopolysaccharide; sMer, soluble Mer; PMA, phrobol 12-myristate 13-acetate; BAL, bronchoalveolar lavage; PI, p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, A Disintegrin And Metalloproteinase; AD, Alzheimer's disease; APP, Amyloid Precursor Protein; AR, Amphiregulin; BTC, Betacellulin; CXCL, CXC, chemokine ligand; EGF, Epidermal growth factor; EGFR, EGF receptor; EPR, Epiregulin; HB-EGF, Heparin-bindin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Expression of KIT in the ovary, and the role of somatic precursor cells

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; AMH, anti-Mullerian hormone; BMP, bone morphogenic protein; CD, cluster of differentiation; c-KIT, cellular KIT; c-PKC, conventional protein kinase C; Cyp 17, cytochrome P450 17alpha-hydroxylase/17,20-lyase; eNos

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2011 سفارش ترجمه

Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism

Keywords: ADAM، disintegrin و متالوپروتئیناز; Prion protein; Transmembrane domain; Membrane topology; α-Cleavage; C1 fragmentα1-3, α-helical structure; β1-2, β-sheet structure; aa, aminoacids; Ab, antibody; ADAM, A disintegrin and metalloproteinase; AP, acceptor peptide; APP, amyloid precursor protei

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Purification and characterization of a fibrinogenolytic and hemorrhagic metalloproteinase isolated from Vipera lebetina venom

Keywords: ADAM، disintegrin و متالوپروتئیناز; Vipera lebetina; VLH2; Fibrinogenolytic enzyme; Hemorrhagic metalloproteinase; Apoptosis-inducing proteaseAEBSF, 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride; ADAM, a disintegrin and metalloproteinase; BAEE, Nα-benzoyl-l-arginine ethyl ester hy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

EGFR signaling in breast cancer: Bad to the bone

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, ADAM with thrombospondin motif; AREG, amphiregulin; CSF-1, colony-stimulating factor-1; DTC, disseminated tumor cell; EGFR, epidermal growth factor receptor; ER, estrogen receptor; OPG, osteoprotegrin; PT

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

TNF blocker drugs modulate human TNF-α-converting enzyme pro-domain shedding induced by autoantibodies

Keywords: ADAM، disintegrin و متالوپروتئیناز; Adalimumab; Autoantibodies; Autoimmune disease; Etanercept; Shedding; TACEAnti-Ro/SSA AutoAbs, antinuclear autoantibodies in the blood directed against Ro/SSA; autoAbs, autoantibodies; ADAM, a disintegrin and metalloproteinase; FACS, Fluorescence-Activate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

ErbB receptor signaling in astrocytes: A mediator of neuron-glia communication in the mature central nervous system

Keywords: ADAM، disintegrin و متالوپروتئیناز; 5-HT, 5-hydroxytryptamine or serotonin; 20-HETE, 20-hydroxyeicosatetraenoic acid; AD, Alzheimer's disease; ADAM, a disintegrin and metalloproteinase; AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AREG, amphiregulin; ATP, adenosine triph

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

Keywords: ADAM، disintegrin و متالوپروتئیناز; MMP, matrix metalloproteinase; TIMP, tissue-inhibitor of metalloproteinases; ECM, extracellular matrix; MMPI, matrix metalloproteinase inhibitor; ADAM, a disintegrin and metalloproteinase; ADAMTS, a disintegrin and metalloproteinase with thrombospondin do

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Mechanism and significance of specific proteolytic cleavage of Reelin

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, ADAM with thrombospondin motifs; FI-1, Furin Inhibitor I; FI-2, Furin Inhibitor II; PC, proprotein convertase; RR, Reelin repeatReelin; Dab1; Phosphorylation; Proteolysis; Heparin; Brain development; Furi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Prolonged inhibition of protein kinase A results in metalloproteinase-dependent platelet GPIbα shedding

Keywords: ADAM، disintegrin و متالوپروتئیناز; GP, glycoprotein; VWF, von Willebrand factor; PKA, protein kinase A; ADAM, a disintegrin and metalloproteinase; GC, glycocalicin; MDL 28170, Carbobenzoxy-valinyl-phenylalaninal; E-64d, (2S, 3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane Ethyl Ester

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; AMPA, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; APP, amyloid precursor protein; CAM, cell adhesion molecule; CX3CL1, CX3C-chemokine ligand 1; CX3CR1, CX3C-chemokine receptor 1; CXCL16, CXC-chemokine l

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein

Keywords: ADAM، disintegrin و متالوپروتئیناز; Aβ, amyloid beta; AD, Alzheimer's disease; ADAM, a disintegrin and metalloproteinase; APP, amyloid precursor protein; BACE1, beta-site APP cleaving enzyme 1; CPM, carboxypeptidase M; GPI, glycosylphosphatidylinositol; GPI-AD10, GPI-anchored ADAM10; hTfR,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

New perspectives on mechanisms underlying chronic allergic inflammation and asthma in 2007

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, A disintegrin and metalloproteinase; CC10, Clara cell protein 10; COPD, Chronic obstructive pulmonary disease; CysLT, Cysteinyl leukotriene; EE, Eosinophilic esophagitis; GILZ, Glucocorticoid-induced leucine zipper; IL-13Rα2, IL-13 receptor α2; IP-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain

Keywords: ADAM، disintegrin و متالوپروتئیناز; ACE, angiotensin-converting enzyme; ADAM, a disintegrin and metalloproteinase; Ang, angiotensin; CaMi, calmodulin inhibitor; Dnp, dinitrophenyl; HEK, human embryonic kidney; Mca, 7-amido-4-methylcoumarin; RAS, renin–angiotensin system; RIPA, radio-immunop

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Glial cross-talk by transmembrane chemokines CX3CL1 and CXCL16

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; CX3CL1, CX3C-chemokine ligand 1; CX3CR1, CX3C-chemokine receptor 1; CXCL16, CXC-chemokine ligand 16; CXCR6, CXC-chemokine receptor 6; PMA, 4-ß-phorbol 12-myristate 13-acetate; GPC, glial precursor cells; MCP-1/CC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; AP-1, activator protein 1; bFGF, basic fibroblast growth factor; EGF, epidermal growth factor; ERK, extracellular-signal related kinase; FCS, fetal calf serum; GFAP, glial fibrillary acidic protein; GPC, glial pr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Structural Determinants of the ADAM Inhibition by TIMP-3: Crystal Structure of the TACE-N-TIMP-3 Complex

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, ADAMs with thrombospondin motifs; β-APP, amyloid precursor protein; cd, catalytic domain; ECM, extracellular matrix; MMP, matrix metalloproteinase; TACE, TNF-α converting enzyme; TIMP, tissue inhibitor of

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

MT1-MMP releases latent TGF-β1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; BSA, bovine serum albumin; ECs, endothelial cells; ECM, extracellular matrix; ERK, extracellular signal-regulated protein kinase; HUVEC, human umbilical vein endothelial cells; LAP, latency associated peptide; LL

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Metalloproteinases and their inhibitors: Regulators of wound healing

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; MMP, matrix metalloproteinase; ECM, extracellular matrix; TIMP, tissue inhibitor of metalloproteinase; RECK, reversion-inducing cysteine-rich protein with Kazal motifs; EMT, epithelial-to-mesenchymal transition;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

NADPH oxidases in lung biology and pathology: Host defense enzymes, and more

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; BCR, B cell receptor; CGD, chronic granulomatous disease; ClC3, chloride channel 3; COPD, chronic obstructive pulmonary disease; DC, dendritic cell; DUOX, dual oxidase; DUOXA, DUOX maturation factor; EGF(R), epid

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, a disintegrin and metalloproteinase with thrombospondin motif; ALP, alkaline phosphatase; BLT, LTB4 receptor; BMP, bone morphogenetic protein; CAIA, collagen antibody-induced arthritis; cAMP, cyclic AMP;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2008 سفارش ترجمه

The role of proteases in pathologies of the synovial joint

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, a disintegrin and metalloproteinase with thrombospondin motifs; Ala, alanine; Asp, aspartic; CD, cluster of differentiation; CLIP, class II invariant chain-associated peptide; COMP, cartilage oligomeric m

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2008 سفارش ترجمه

Crystal structure of RVV-X: An example of evolutionary gain of specificity by ADAM proteinases

Keywords: ADAM، disintegrin و متالوپروتئیناز; RVV-X, Russell’s viper venom factor X activator; ADAM, a disintegrin and metalloproteinase; MDC, metalloproteinase/disintegrin/cysteine-rich; HVR, hyper-variable-region; PEG, polyethyleneglycolMetalloproteinase; Disintegrin; ADAM; Factor X activator; Snak

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Prolyl, cystyl and pyroglutamyl peptidase activities in the hippocampus and hypothalamus of streptozotocin-induced diabetic rats

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, A disintegrin and metalloproteinase; APM, aminopeptidase M; AVP, vasopressin; BSA, Bovine serum albumin; CAP, cystinyl or cystyl aminopeptidase; CSF, cerebrospinal fluid; DPPIV, dipeptidyl-peptidase IV; DTT, dl-dithiothreitol; EDTA, ethylenediamine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Novel function of human ADAM15 disintegrin-like domain and its derivatives in platelet aggregation

Keywords: ADAM، disintegrin و متالوپروتئیناز; A15Dis, ADAM 15 disintegrin-like domain; ADAM, A Disintegrin and Metalloproteinase; ADP, adenosine diphosphate; BSA, bovine serum albumin; ELISA, enzyme-linked immunosorbent assay; FITC, fluorescein isothiocyanate; GRGDSP, Gly–Arg–Gly–Asp–Ser–Pro; KGD, Ly

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Crystal Structures of Human ADAMTS-1 Reveal a Conserved Catalytic Domain and a Disintegrin-like Domain with a Fold Homologous to Cysteine-Rich Domains

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; ADAMTS, a disintegrin-like and metalloproteinase domain with thrombospondin type I motifs; MMP, matrix metalloproteinase; S-SAD, sulphur SADADAMTS-1; metalloproteinase; X-ray structure

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

The allergic cascade: Review of the most important molecules in the asthmatic lung

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; AHR, airway hyperresponsiveness; APCs, antigen-presenting cells; ASM, airway smooth muscle; BAL, bronchoalveolar lavage; BECs, bronchial epithelial cells; bFGF, basic fibroblast growth factor; CCL, CC-chemokine l

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Breaking up the tie: Disintegrin-like metalloproteinases as regulators of cell migration in inflammation and invasion

Keywords: ADAM، disintegrin و متالوپروتئیناز; ADAM, a disintegrin and metalloproteinase; APP, amyloid precursor protein; CAM, cell adhesion molecule; CHL1, close homologue of L1; ECM, extracellular matrix; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; GPCR, G protein-coupled r

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2006 سفارش ترجمه