Metalloproteinase Gene Expression Correlates With Clinical Outcome in Dupuytren's Disease
Keywords: ADAMTS; Dupuytren's Disease; gene expression; MMP; TIMP
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Proprotein convertase activation of aggrecanases in cartilage in situ
Keywords: Aggrecanase; ADAMTS; PACE4; Proprotein convertase; Cartilage; Osteoarthritis; Metalloproteases; Post-translational activation
ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques
Keywords: ADAMTS; Atherosclerosis; Inflammation; Macrophages; Matrix-degrading proteases
Synthetic active site-directed inhibitors of metzincins: Achievement and perspectives
Keywords: MMPs; Matrix metalloproteinase; Zinc protease; Inhibitor; Hydroxamate; Phosphinic peptide; Inhibitor design; ADAM; ADAMTS
Evidence from limited proteolysis of a ristocetin-induced conformational change in human von Willebrand factor that promotes its binding to platelet glycoprotein Ib-IX-V
Keywords: ADAMTS; a disintegrin-like and metalloprotease with thrombospondin type-1 motif; l-BAPNA; Nα-benzoyl-l-arginine-p-nitroanilide; GP Ib-IX-V; glycoprotein Ib-IX-V; GP IIb-IIIa; glycoprotein IIb-IIIa; VWD; von Willebrand disease; VWF; von Willebrand factor;
Specific targeting of metzincin family members with small-molecule inhibitors: Progress toward a multifarious challenge
Keywords: Matrix metalloproteinases; MMP; Metzincins; ADAM; ADAMTS; PCP; Procollagen C-proteinase; Selective; Inhibitor; Specific; Zn-metalloproteinases; TACE; Hydroxamate; Phosphinic; Zinc-binding group
A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease
Keywords: ADAMTS; Dupuytren’s disease; gene expression; MMP; TIMP
ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis
Keywords: Extracellular matrix; ADAMTS; ADAMTS-like; Myogenesis; Glycoprotein
Signaling pathways implicated in oncostatin M-induced aggrecanase-1 and matrix metalloproteinase-13 expression in human articular chondrocytes
Keywords: Arthritis; Human chondrocytes; Matrix metalloproteinase; ADAMTS; Oncostatin M; Cell signaling
Differential expression of ADAMTS-1, -4, -5 and TIMP-3 in rat spinal cord at different stages of acute experimental autoimmune encephalomyelitis
Keywords: ADAMTS; EAE; Extracellular matrix; Inflammation; Brain
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: Comparative analyses with ADAMTS-5, -9, -16 and -18
Keywords: ADAMTS; Aggrecan; aggrecanase; Glycosaminoglycan-binding; Metalloproteinase; Proteoglycan
Expression of aggrecan(ases) during murine preadipocyte differentiation and adipose tissue development
Keywords: Aggrecan; ADAMTS; Obesity; Adipogenesis
A suite of parallel vectors for baculovirus expression
Keywords: Recombinant baculoviruses; Expression vector; MBP; GFP; Kinase; ADAMTS; Folding; High throughput
Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression
Keywords: MMP; ADAMTS; Fracture healing; Transcriptional profiling
Metalloproteinase ADAMTS-1 but not ADAMTS-5 is manifold overexpressed in neurodegenerative disorders as Down syndrome, Alzheimer's and Pick's disease
Keywords: Disorders of the nervous system; Degenerative disease: other; Metalloproteinase; ADAMTS; Neurodegeneration; Down syndrome; Alzheimer's disease; Pick's disease;
The characterisation of six ADAMTS proteases in the basal chordate Ciona intestinalis provides new insights into the vertebrate ADAMTS family
Keywords: ADAMTS; a disintegrin-like and metalloprotease domain [reprolysin-type] with thrombospondin type-1 motif; ADAMTSL; ADAMTS-like; CUB; complement subcomponent C1r/C1s/embryonic sea urchin protein Uegf/Bone morphogenic protein 1; IGCAM; Immunoglobulin cell a
Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration
Keywords: Aggrecanase; Matrix metalloproteinases; Cartilage catabolism; MMP; matrix metalloproteinase; IL-1; interleukin-1; OSM; oncostatin M; GAG; glycosaminoglycan; IGD; interglobular domain of the aggrecan core protein; DMMB; dimethylmethylene blue; MAb; monoclo
Adamts9 is widely expressed during mouse embryo development
Keywords: ADAMTS; Metalloprotease; ADAMTS9; ADAMTS20; gon-1; Aggrecan; Versican; Belted; In situ hybridization; Mouse; Embryogenesis; Mesoderm; Rathke's pouch; Trophoblast; Endochondral ossification; ADAMTS; a disintegrin-like and metalloprotease domain with thromb
The hyalectan degrading ADAMTS-1 enzyme is expressed by osteoblasts and up-regulated at regions of new bone formation
Keywords: Osteoblasts; Proteoglycan; Metalloproteinase; Osteogenesis; ADAMTS;
Analysis of full length ADAMTS6 transcript reveals alternative splicing and a role for the 5â² untranslated region in translational control
Keywords: ADAMTS; A-disintegrin-and-metalloproteinase with thrombospondin-1 type repeats; MMP; matrix metalloproteinase; TNFα; tumour necrosis factor alpha; RACE; rapid amplification of cDNA ends; UTR; untranslated region; IRES; internal ribosome entry site; Metal
Phenotypic characterization of chondrosarcoma-derived cell lines
Keywords: Chondrocyte; Cell line; Expression analysis; Functional genomics; ADAMTS; a disintegrin and metalloproteinase with thrombospondin type 1 motif; Col; collagen; IL-1β; interleukin 1β; MMP; matrix metalloproteinases; OA; osteoarthritic; qPCR; quantitative
Functions for proteinases in the ovulatory process
Keywords: PA; plasminogen activator; uPA; urokinase-type PA; tPA; tissue-type PA; MMP; matrix metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondine motifs; PAPP-A; pregnancy-associated plasma protein-A; Ovulation; MMP; PA/plasmin; ADAM