Keywords: گیرنده آدنوزین A2A; Cordycepin; Spontaneous alternation behavior; Hippocampus; Adenosine; Adenosine A2A receptor; Adenosine A1 receptor;
مقالات ISI گیرنده آدنوزین A2A (ترجمه نشده)
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Keywords: گیرنده آدنوزین A2A; Adora2a; adenosine A2a receptor; ACTH; adrenocorticotropic hormone; AVP; arginine vasopressin; α-CaMKII; Ca2+/calmodulin-dependent protein kinase II-α; β-actin; Rattus norvegicus actin, beta; cAMP; cyclic adenosine monophosphate; CORT; corticosterone;
Keywords: گیرنده آدنوزین A2A; hA1AR; human adenosine A1 receptor; hA2AAR; A2AR, human adenosine A2A receptor; hA2BAR; human adenosine A2B receptor; hA3AR; human adenosine A3 receptor; ADORA2A; adenosine A2A receptor gene; AR; adenosine receptor; cAMP; cyclic adenosine 5â²-monophospha
Keywords: گیرنده آدنوزین A2A; Restless Legs Syndrome; Brain iron deficiency; Adenosine A1 receptor; Adenosine A2A receptor; Dopamine D2 receptor
Keywords: گیرنده آدنوزین A2A; A1AR; adenosine A1 receptor; A2AAR; adenosine A2A receptor; A2BAR; adenosine A2B receptor; A3AR; adenosine A3 receptor; MG; myasthenia gravis; EAMG; experimental autoimmune myasthenia gravis; AChR; acetylcholine receptor; AChR R97-116; rat AChR α97-116 p
Keywords: گیرنده آدنوزین A2A; Sickle cell disease; Adenosine; Adenosine A2A receptor; Adenosine A2B receptor; NKT cells;
Keywords: گیرنده آدنوزین A2A; Rubimetide; Rubisco; MMK1; Humanin; Anxiolytic-like activity; FPR2; Prostaglandin D2; DP1 receptor; Adenosine A2A receptor; GABAA receptor
Keywords: گیرنده آدنوزین A2A; Guanidines; A2A receptor; Privileged structure; Iminoimidazoline; Tic-H; tetrahydroisoquinoline-hydantoin; A2AR; adenosine A2A receptor;
Early-life hyperthermic seizures upregulate adenosine A2A receptors in the cortex and promote depressive-like behavior in adult rats
Keywords: گیرنده آدنوزین A2A; HIS; hyperthermia-induced seizures; A2AR; adenosine A2A receptor; AC; adenylate cyclase; PD; postnatal day; Febrile seizures; Adenosine A2A receptors; Cortex; Depression; Rat; Adulthood;
Impact of adenosine A2a receptor polymorphism rs5751876 on platelet reactivity in ticagrelor treated patients
Keywords: گیرنده آدنوزین A2A; Ticagrelor; Platelet activation; Adenosine A2a receptor; Single nucleotide polymorphism; Percutaneous coronary intervention;
Benzopyrone represents a privilege scaffold to identify novel adenosine A1/A2A receptor antagonists
Keywords: گیرنده آدنوزین A2A; Benzopyrone; Adenosine A2A receptor; Adenosine A1 receptor; Antagonist; GTP shift; Radioligand binding assay; Cancer; Parkinson's disease; AR; adenosine receptor; GTP; guanosine triphosphate; [3H]DPCPX; [3H]-dipropyl-8-cyclopentylxanthine; [3H]NECA; N-[3H
The adenosine A2A receptor agonist T1-11 ameliorates neurovisceral symptoms and extends the lifespan of a mouse model of Niemann-Pick type C disease
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Niemann-Pick C; Cholesterol; T1-11;
Inhibition of astrocytic adenosine receptor A2A attenuates microglial activation in a mouse model of Sandhoff disease
Keywords: گیرنده آدنوزین A2A; Sandhoff disease; HexB knockout mice; Adenosine A2A receptor; Astrogliosis; Istradefylline; SD; Sandhoff disease; Hex; β-hexosaminidase; A2AR; Adenosine receptor A2A;
Adenosine A2A receptor gene polymorphisms (ADORA2A) are associated with maximal concentric contraction pain
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; ADORA2A; Caffeine; Eccentric exercise; Pain;
Adenosine A2A receptor involves in neuroinflammation-mediated cognitive decline through activating microglia under acute hypobaric hypoxia
Keywords: گیرنده آدنوزین A2A; Hypobaric hypoxia; Adenosine A2A receptor; Microglia; Hippocampus; Neuroinflammation; Cognitive impairment;
Remote control of movement disorders using a photoactive adenosine A2A receptor antagonist
Keywords: گیرنده آدنوزین A2A; Movement disorder; Adenosine A2A receptor; Photopharmacology; SCH442416; Locomotor activity; Catalepsy; Tremor; Parkinson's disease;
The Corticostriatal Adenosine A2A Receptor Controls Maintenance and Retrieval of Spatial Working Memory
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; OptoA2AR; Parkinson's disease; Prefrontal cortex; Spatial working memory; Striatum;
Occupancy of adenosine A2A receptors by istradefylline in patients with Parkinson's disease using 11C-preladenant PET
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Istradefylline; Parkinson's disease; PET; 11C-preladenant;
Functional histamine H3 and adenosine A2A receptor heteromers in recombinant cells and rat striatum
Keywords: گیرنده آدنوزین A2A; A2AR; Adenosine A2A receptor; cAMP; Cyclic adenosine monophosphate; D1R; Dopamine D1 receptor; D2R; Dopamine D2 receptor; dMSNs; Direct pathway striatal medium-sized spiny neurons; GABA; γ-Aminobutyric acid; GPCRs; G-protein coupled receptors; H2R; Hista
Expressions of adenosine A2A receptors in coronary arteries and peripheral blood mononuclear cells are correlated in coronary artery disease patients
Keywords: گیرنده آدنوزین A2A; Coronary artery disease; Adenosine A2A receptor; Ischemia;
A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment
Keywords: گیرنده آدنوزین A2A; A2aR; adenosine A2a receptor; CAF; cancer-associated fibroblast; CHO; Chinese hamster ovary; IC50; concentration of compound that displaces the binding of radioligand by 50%; Kb; binding constant; Ki; inhibition constant; NECA; 5â³-N-ethylcarboxamidoaden
Research PaperCocaine self-administration specifically increases A2AR-D2R and D2R-sigma1R heteroreceptor complexes in the rat nucleus accumbens shell. Relevance for cocaine use disorder
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Cocaine self-administration; Dopamine D2 receptor; Heteroreceptor complexes; Sigma 1 receptor; Substance use disorder;
Method for rapid optimization of recombinant GPCR protein expression and stability using virus-like particles
Keywords: گیرنده آدنوزین A2A; GPCR recombinant protein expression; Protein engineering; Virus-like particles; GPCR protein stabilization; Membrane protein; A2A; Adenosine A2A Receptor; eGFP; enhanced Green Fluorescent Protein; ESI; Electrospray Ionization; GALR3; Galanin Receptor Type
Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells
Keywords: گیرنده آدنوزین A2A; A1R; adenosine A1 receptor; A2AR; adenosine A2A receptor; A2BR; adenosine A2B receptor; A3R; adenosine A3 receptor; MAPK; mitogen activated protein kinase; NECA; 5â²-N-ethylcarboxamidoadenosine; PI3K; phosphatidylinositol-3â²-kinase; Macrophage; Chemota
Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation
Keywords: گیرنده آدنوزین A2A; Caffeine; Cannabinoid receptor 1; Adenosine A2A receptor; Istradefylline; Novel object recognition; Memory; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; A1R; adenosine A1 receptor; A2AR; adenosine A
Adenosine A2a receptor stimulation blocks development of nonalcoholic steatohepatitis in mice by multilevel inhibition of signals that cause immunolipotoxicity
Keywords: گیرنده آدنوزین A2A; A2aR; adenosine A2a receptor; Th; T helper; NASH; nonalcoholic steatohepatitis; MCD; methionine-choline deficient; IL; interleukin; WT; wild type; NAFLD; nonalcoholic fatty liver disease; Treg; T regulatory; IFN; interferon; TNF; tumor necrosis factor; TG
Original Research ArticleReduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Coronary reactive hyperemia; Ï-hydroxylases; Soluble epoxide hydrolase; Heart perfusate oxylipins; Plasma oxylipins;
Chronic oral administration of MPEP, an antagonist of mGlu5 receptor, during gestation and lactation alters mGlu5 and A2A receptors in maternal and neonatal brain
Keywords: گیرنده آدنوزین A2A; ADA; adenosine deaminase; AMPA; (RS)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; A2AR; adenosine A2A receptor; a.u.; arbitrary units; DHPG; (S)-3,5-dihydroxyphenylglycine; EGTA; ethylene glycol-bis(β-aminoethyl ether)-N,N,Nâ²,Nâ²-tetraacetic
Genetic deletion of GPR52 enhances the locomotor-stimulating effect of an adenosine A2A receptor antagonist in mice: A potential role of GPR52 in the function of striatopallidal neurons
Keywords: گیرنده آدنوزین A2A; ADORA2A; adenosine A2A receptor; DRD1; dopamine D1 receptor; DRD2; dopamine D2 receptor; GPCR; G protein-coupled receptor; KO; knockout; NMDA; N-methyl-d-aspartate; mAb; monoclonal antibody; qPCR; quantitative polymerase chain reaction; WT; wild type; GPR
Calcium modulates calmodulin/α-actinin 1 interaction with and agonist-dependent internalization of the adenosine A2A receptor
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Alpha-actinin; GPCR; Actin; Crosslinking; Internalization; Desensitization; Ca2Â + binding; Carboxyl terminus;
Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists
Keywords: گیرنده آدنوزین A2A; Structure-affinity relationships; Adenosine A1 receptor; Adenosine A2A receptor; Selectivity; Antagonists;
Down-regulation of adenosine A1 and A2A receptors in peripheral cells from idiopathic normal-pressure hydrocephalus patients
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Adenosine A1 receptor; Idiopathic normal-pressure hydrocephalus;
Alterations in ventral and dorsal striatal allosteric A2AR-D2R receptor-receptor interactions after amphetamine challenge: Relevance for schizophrenia
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Dopamine D2 receptor; Heteroreceptor complexes; Schizophrenia; Amphetamine; Allosteric receptor-receptor interaction;
Cocaine self-administration differentially affects allosteric A2A-D2 receptor-receptor interactions in the striatum. Relevance for cocaine use disorder
Keywords: گیرنده آدنوزین A2A; Cocaine self-administration; Dopamine D2 receptor; Adenosine A2A receptor; Allosteric receptor-receptor interactions; Heteroreceptor complex; Addiction
Evaluation of antidepressant-like and anxiolytic-like activity of purinedione-derivatives with affinity for adenosine A2A receptors in mice
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Antidepressant activity; Imidazo[2,1-f]purinediones; Pyrimido[2,1-f]purinediones;
Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1
Keywords: گیرنده آدنوزین A2A; Niemann-Pick C; Adenosine A2A receptor; Cholesterol; Mitochondrial membrane potential; Neuroblastoma cell line; Oligodendroglial cell line;
Guanosine may increase absence epileptic activity by means of A2A adenosine receptors in Wistar Albino Glaxo Rijswijk rats
Keywords: گیرنده آدنوزین A2A; A1R; adenosine A1 receptor; A2AR; adenosine A2A receptor; Ado; adenosine; ADP; Ado diphosphate; AMP; Ado monophosphate; ATPA; do triphosphate; CNS; central nervous system; COX; cyclooxygenase; DMSO; dimethyl sulfoxide; EEG; electroencephalogram; FFT; Fast
Research PaperAberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy
Keywords: گیرنده آدنوزین A2A; α-Syn; α-synuclein; A2AR; adenosine A2A receptor; AD; Alzheimer's disease; DG; dentate gyrus; DLB; dementia with Lewy bodies; HD; Huntington's disease; KO; knockout; LBs; Lewy bodies; LNs; Lewy neurites; MSA; multiple system atrophy; PD; Parkinson's dis
Activation of the adenosine A2A receptor attenuates experimental autoimmune encephalomyelitis and is associated with increased intracellular calcium levels
Keywords: گیرنده آدنوزین A2A; A2AR; adenosine A2A receptor; CFA; complete Freund's adjuvant; CGS; CGS21680; CRAC; Ca2+ release-activated calcium; EAE; experimental autoimmune encephalomyelitis; FITC; fluorescein isothiocyanate; MS; multiple sclerosis; PBS; phosphate-buffered saline;
Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury
Keywords: گیرنده آدنوزین A2A; Hippocampal neurotoxicity; Cerebral ischemia; Adenosine A1 receptor; AMPAR trafficking; Serine/threonine protein phosphatase; Adenosine-induced persistent synaptic depression; CPA; N6-cyclopentyl adenosine; DPCPX; 8-cyclopentyl-1,3-dipropylxanthine; APSD;
Allosteric mechanisms within the adenosine A2A-dopamine D2 receptor heterotetramer
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Dopamine D2 receptor; Heteromer; Striatum; Caffeine; Parkinson's disease;
Adenosine A2A receptor signaling attenuates LPS-induced pro-inflammatory cytokine formation of mouse macrophages by inducing the expression of DUSP1
Keywords: گیرنده آدنوزین A2A; A2AR; adenosine A2A receptor; AP-1; activator protein 1; BLC; B-lymphocyte chemoattractant; BMDM; bone marrow derived macrophage; CREB; cAMP response element-binding protein; DUSP1; dual specific phosphatase; Epac; exchange protein activated by cAMP; ERK;
Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure-induced transient ischemic injury
Keywords: گیرنده آدنوزین A2A; A2AR; adenosine A2A receptor; CNS; central nervous system; CTCF; corrected total cell fluorescence; EDTA; ethylenediamine tetraacetic acid; EGTA; ethylene glycol tetraacetic acid; EHP; elevated hydrostatic pressure; FBS; fetal bovine serum; GCL; ganglion
Whole transcriptome microarrays identify long non-coding RNAs associated with cardiac hypertrophy
Keywords: گیرنده آدنوزین A2A; Microarray; Long non-coding RNA; Adenosine A2a receptor; Transverse aortic constriction
Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; hERG; MK-499; Docking; Superposition; Transformation
Animal models of Parkinson׳s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535)
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Parkinson׳s disease; Catalepsy; Motor activity; 6-OHDA model;
Modulatory effects of inosine, guanosine and uridine on lipopolysaccharide-evoked increase in spike-wave discharge activity in Wistar Albino Glaxo/Rijswijk rats
Keywords: گیرنده آدنوزین A2A; NF-κB; nuclear factor kappa B; A2AR; adenosine A2A receptor; Ado; adenosine; AP5; 2-amino-5-phosphonopentanoic acid; CNS; central nervous system; COX-2; cyclooxygenase-2; EEG; electroencephalogram; GABAA receptors; GABAA type of gamma-aminobutyric acid r
Salidroside attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A2a receptor related mitochondria-dependent apoptosis pathway
Keywords: گیرنده آدنوزین A2A; PAH; pulmonary arterial hypertension; PASMCs; pulmonary arterial smooth muscle cells; A2aR; adenosine A2a receptor; COPD; chronic obstructive pulmonary disease; HUVECs; human umbilical vein endothelial cells; MYH11; smooth muscle myosin heavy chain 11; RV
Improvement of mitochondrial NAD+/FAD+-linked state-3 respiration by caffeine attenuates quinolinic acid induced motor impairment in rats: Implications in Huntington's disease
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; Caffeine; Mitochondria; Oxidative stress
Increased striatal adenosine A2A receptor levels is an early event in Parkinson's disease-related pathology and it is potentially regulated by miR-34b
Keywords: گیرنده آدنوزین A2A; Adenosine A2A receptor; ADORA2A; miR-34b; Putamen; Parkinson's disease; Post-mortem;