Keywords: AGD، Anogenital distance; AGD, anogenital distance; BMD, bone mineral density; BW, body weight; ER, estrogen receptor; PND, postnatal dayDaidzein; Bone mineral density; Safety; Perinatal period; Timing of exposure
مقالات ISI AGD، Anogenital distance (ترجمه نشده)
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Effects of the environmental estrogenic contaminants bisphenol A and 17α-ethinyl estradiol on sexual development and adult behaviors in aquatic wildlife species
Keywords: AGD، Anogenital distance; AGD, anogenital distance; AR, androgen receptor; AOPs, adverse outcome pathways; BMPO, benzo(a)pyrene monooxygenase; BPA, bisphenol A; CYP1A1, cytochrome P450 family 1 subfamily A polypeptide 1; Cyp19a1a, aromatase; DES, diethylstilbestrol; DDE, dichlorod
Effects of n-butylparaben on steroidogenesis and spermatogenesis through changed E2 levels in male rat offspring
Keywords: AGD، Anogenital distance; Parabens; Endocrine disrupting chemicals; Reproduction; Testosterone; Oestrogenen-BP, n-butylparaben; GD, gestation day; PND, postnatal day; EDCs, endocrine disrupting chemicals; AGD, anogenital distance; TD, testicular descent; PPS, preputial separation;
Dose-related effect by maternal exposure to di-(2-ethylhexyl) phthalate plasticizer on inducing hypospadiac male rats
Keywords: AGD، Anogenital distance; DEHP, di-(2-ethylhexyl) phthalate; GD, gestation day; BW, body weight; EEDs, environmental endocrine disruptors; PND, postnatal day; AGD, anogenital distance; DBP, di-n-butyl phthalateDi-(2-ethylhexyl) phthalate; Plasticizer; Hypospadias; External genital
Prenatal developmental toxicity studies on diundecyl and ditridecyl phthalates in Sprague-Dawley rats
Keywords: AGD، Anogenital distance; AGD, anogenital distance; DEHP, diethylhexyl phthalate; DIDP, diisodecyl phthalate; DINP, diisononyl phthalate; DTDP, ditridecyl phthalate; DUDP, diundecyl phthalate; GD, gestation day; HMWPE, high molecular weight phthalate esters; NOAEL, no-observed-adv
Endocrine disrupting effects in rats perinatally exposed to a dietary relevant mixture of phytoestrogens
Keywords: AGD، Anogenital distance; AGD, anogenital distance; DMBA, 7,12-dimethylbenz(a)anthracene; GD, gestation day; MNU, N-nitroso-N-methylurea; PND, postnatal day; SECO, secoisolariciresinol; TEB, terminal end budMammary; Histology; Daidzein; Genistein; Secoisolarici resinol; Lignans; D
A dose response study to assess effects after dietary administration of diisononyl phthalate (DINP) in gestation and lactation on male rat sexual development
Keywords: AGD، Anogenital distance; AGD, anogenital distance; DiNP, diisononyl phthalate; DBP, dibutyl phthalate; DEHP, diethylhexyl phthalate; DEP, diethyl phthalate; DMP, dimethyl phthalate; GD, gestation day; LCA, Leydig cell aggregates; MNG, multinucleated gonocytes; NOEL, no adverse ef
An approach for integrating toxicogenomic data in risk assessment: The dibutyl phthalate case study
Keywords: AGD، Anogenital distance; ADME, absorption, distribution, metabolism, and excretion; AGD, anogenital distance; ALDH2, aldehyde dehydrogenase-2; AR, androgen receptor; BBDR model, biologically based dose–response model; CNPs, copy number polymorphisms; CYP2D6, cytochrome P450 2D6;
Use of genomic data in risk assessment case study: I. Evaluation of the dibutyl phthalate male reproductive development toxicity data set
Keywords: AGD، Anogenital distance; AGD, anogenital distance; BMDL, benchmark dose lower confidence limit; DBP, dibutyl phthalate; GD, gestation day; IRIS, Integrated Risk Information System; LOEL, lowest-observed-effect level; LOAEL, lowest-observed-adverse-effect level; MOA, mode of actio
Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set
Keywords: AGD، Anogenital distance; AGD, anogenital distance; BBP, benzyl butyl phthalate; DBP, dibutyl phthalate; DEG, differentially-expressed gene; DEHP, di-(2-ethylhexyl) phthalate; DEP, diethyl phthalate; DMP, dimethyl phthalate; DOTP, dioctyl tere-phthalate; DPP, dipentyl phthalate; E
Disposition of diiosononyl phthalate and its effects on sexual development of the male fetus following repeated dosing in pregnant rats
Keywords: AGD، Anogenital distance; AGD, anogenital distance; DiNP, diisononyl phthalate; DBP, dibutyl phthalate; DEHP, diethylhexyl phthalate; FW, fetal weight; GD, gestation day; LCA, Leydig cell aggregates; LW, liver weight; MCiOP, mono(carboxy-isooctyl) phthalate; MEHP, mono-(2-ethyhexy
The role of androgen-induced growth factor (FGF8) on genital tubercle development in a hypospadiac male rat model of prenatal exposure to di-n-butyl phthalate
Keywords: AGD، Anogenital distance; DBP, di-n-butyl phthalate; EEDs, environmental endocrine disruptors; GD, gestation day; PND, postnatal day; BW, body weight; AGD, anogenital distance; T, testosterone; AR, androgen receptor; FGF8, fibroblast growth factor 8; AIGF, androgen-induced growth
Prenatal exposure to di-n-butyl phthalate induces anorectal malformations in male rat offspring
Keywords: AGD، Anogenital distance; DBP, di-n-butyl phthalate; ARMs, anorectal malformations; GD, gestation day; PND, postnatal day; BW, bodyweight; AGD, anogenital distance; T, testosterone; AR, androgen receptor; Shh, sonic hedgehog; Bmp4, bone morphogenetic protein; PAEs, phthalic acid e
Impaired oligodendroglial development by decabromodiphenyl ether in rat offspring after maternal exposure from mid-gestation through lactation
Keywords: AGD، Anogenital distance; AGD, anogenital distance; BFR, brominated flame retardant; CNPase, 2′,3′-cyclic nucleotide 3′-phosphodiesterase; CYP, cytochrome P450; DBDE, decabromodiphenyl ether; GD, gestation day; NeuN, neuron-specific nuclear protein; PBDEs, polybrominated diphenyl
Prenatal developmental toxicity studies on di-n-heptyl and di-n-octyl phthalates in Sprague-Dawley rats
Keywords: AGD، Anogenital distance; AGD, anogenital distance; BMD, benchmark dose; BMDL, benchmark dose limit; DEHP, diethylhexyl phthalate; DIBP, diisobutyl phthalate; DIHP, diisoheptyl phthalate; DBP, di-n-butyl phthalate; DHPP, di-n-heptyl phthalate; DnOP, di-n-octyl phthalate; GD, gesta
Paternal treatment with cisplatin impairs reproduction of adult male offspring in rats
Keywords: AGD، Anogenital distance; AGD, anogenital distance; BEP, bleomycin, etoposide and cisplatin; CP, cisplatin; GD, gestational day; PND, postnatal dayCisplatin; Paternal exposure; Adult male progeny; Reproduction
Reproductive and developmental toxicities of zinc supplemented rats
Keywords: AGD، Anogenital distance; AGD, Anogenital distance; ALP, Alkaline phosphatase; ALT, Alanine aminotransferase; BUN, Blood urea nitrogen; GD0, Gestational day zero; γ-GGT, Gamma-glutamyl transferase; HGB, Hemoglobin; MCHC, Mean corpuscular hemoglobin concentration; MCV, Mean corpusc
Phthalate Exposure and Precocious Puberty in Females
Keywords: AGD، Anogenital distance; AGD, Anogenital distance; BMI, Body mass index; CDC, Centers for Disease Control and Prevention; CPP, Central precocious puberty; DBP, Di-n-butyl phthalate; DEHP, Di-(2-ethylhexyl) phthalate; EDC, Endocrine-disrupting chemical; LOD, Limit of detection; MB
Prenatal exposure to diesel exhaust particles and effect on the male reproductive system in mice
Keywords: AGD، Anogenital distance; AGD, anogenital distance; AMH, anti-Müllerian hormone; AR, androgen receptor; AQP, aquaporin; BSA, bovine serum albumin; DE, diesel exhaust; DEP, diesel exhaust particles; DSP, daily sperm production; ER, estrogen receptor; FSHr, follicle-stimulating horm
In Utero Exposure to Benzophenone-2 Causes Hypospadias Through an Estrogen Receptor Dependent Mechanism
Keywords: AGD، Anogenital distance; urethra; hypospadias; endocrine disruptors; benzophenone; receptors; estrogen3D, 3-dimensional; AGD, anogenital distance; AGDI, AGD index; BP2, benzophenone-2; ER, estrogen receptor; GD, gestational day; GT, genital tubercle; PCR, polymerase chain reactio
Phthalate exposure and male infertility
Keywords: AGD، Anogenital distance; AGD, anogenital distance; BBP, butylbenzylphthalate; COX-2, cyclooxygenase-2; DBP, di-n-butylphthalate; DEHP, di-(2-ethylhexyl)phthalate; DEP, diethylphthalate; DHT, dihydrotestosterone; DiBuP, di-iso-butylphthalate; DiNP, di-isononylphthalate; DnBuP, di-