Potential protective mechanisms of aryl hydrocarbon receptor (AHR) signaling in benign prostatic hyperplasia
Keywords: AHR; Prostate; BPH; Development; Vasculature; Androgen
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Regulation of Bach2 by the aryl hydrocarbon receptor as a mechanism for suppression of B-cell differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin
Keywords: Bach2; AHR; 2,3,7,8-Tetrachlorodibenzo-p-dioxin; B-cell differentiation
Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation
Keywords: Obesity; asthma; bariatric surgery; weight loss; airway hyperreactivity; CD4 T cell; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; BMI; Body mass index;
Discovery and biological characterization of 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole as an aryl hydrocarbon receptor activator generated by photoactivation of tryptophan by sunlight
Keywords: Abbreviations; AHR; aryl hydrocarbon receptor; aTRP; sunlight-activated tryptophan; CEH; chick embryo hepatocytes; CID; collision-induced dissociation; CYP; cytochrome P450; EROD; 7-ethoxyresorufin deeethylase; ESIMS; electrospray ionization mass spectrom
Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line
Keywords: CYP; cytochrome P450; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; DRE; dioxin response element; EROD; 7-ethoxyresorufin O-deethylation; B[a]P; benzo[a]pyrene; BNF; β-naphthoflavone; TIIA; tanshinone IIA; CTS; cry
Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation
Keywords: Dioxin; AhR; SOS1; Ras; Cell proliferation
Biological and chemical studies on aryl hydrocarbon receptor induction by the p53 inhibitor pifithrin-α and its condensation product pifithrin-β
Keywords: Pifithrin alpha; Pifithrin beta; AhR; CYP1A; Transcriptional response; Computational modeling
Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells
Keywords: Long-term estrogen exposure; AhR; STAT1; Gene expression; Breast cancer
Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFκB and AhR and EGFR-ERK pathway
Keywords: AhR; Cytokines; EGFR; Keratinocytes; Plant polyphenols; UVAÂ +Â UVB;
Developmental effects related to angiogenesis and osteogenic differentiation in Salmon larvae continuously exposed to dioxin-like 3,3′,4,4′-tetrachlorobiphenyl (congener 77)
Keywords: Dioxin-like PCB; Yolk-sac larvae; Development; Osteogenesis; Angiogenesis; AhR
Prenatal administration of the cytochrome P4501A inducer, Î-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: Implications for bronchopulmonary dysplasia (BPD) in premature infants
Keywords: BPD; bronchopulmonary dysplasia; CYP; cytochrome P450; BNF; Ã-napthoflavone; CO; corn oil; EROD; ethoxyresorufin O-deethylase; MROD; methoxyresorufin O-demethylase; ROS; reactive oxygen species; MC; 3-methylcholanthrene; AHR; Ah receptor; RT-PCR; reverse
Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract
Keywords: Crohn's disease; Colitis; T-helper cells; Immune Regulation; AhR; Aryl hydrocarbon receptor; DSS; dextran sulfate sodium; Ficz; 6-formylindolo(3, 2-b)carbazole; IFN; interferon; IL; interleukin; LPMC; lamina propria mononuclear cell; Th; T-helper; TNBS; t
Association Between CHADS2 Risk Factors and Anticoagulation-Related Bleeding: A Systematic Literature Review
Keywords: AF; atrial fibrillation; AHR; adjusted hazard ratio; AOR; adjusted odds ratio; CHADS2; chronic heart failure, hypertension, advanced age, diabetes, and prior stroke/transient ischemic attack; CHF; chronic heart failure; CI; confidence interval; CVD; cereb
The extra domain AÂ of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice
Keywords: Airway remodeling; asthma; EDA-containing fibronectin; fibroblast; fibrosis; myofibroblast; AHR; Airway hyperresponsiveness; α-SMA; α-Smooth muscle actin; ASM; Airway smooth muscle; BAL; Bronchoalveolar lavage; Ct; Cycle threshold; ECM; Extracellular ma
Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2
Keywords: AhR; aryl hydrocarbon receptor; AhRR; AhR repressor; AIP; aryl hydrocarbon receptor interacting protein; ARE; anti-oxidant response element; ARNT; aryl hydrocarbon receptor nuclear translocator; BaP; benzo[a]pyrene; CYP; cytochrome P450; EROD; ethoxyresor
The increasing challenge of discovering asthma drugs
Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; bn; billion; cysLT; cysteinyl leukotrienes; DZ; dizygotic; EAR; early airway response; FDA; Food and Drug
A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma
Keywords: Goblet cells; SPDEF; IL-13; hyperplasia; AHR; Airway hyperresponsiveness; APTI; Airway pressure time index; BALF; Bronchoalveolar lavage fluid; CLCA3; Calcium activated chloride channel 3; FOXA3; Forkhead box transcription factor A3; HBEC; Human bronchial
IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation
Keywords: Allergic inflammation; asthma; IL-22; eosinophils; IL-25; AHR; Airway hyperresponsiveness; BALF; Bronchoalveolar lavage fluid; BMDC; Bone marrow-derived dendritic cell; IL-10R2; IL-10 receptor 2; IL-22R1; IL-22 receptor 1; LTi; Lymphoid tissue inducer;
Adaptive response to oxidative stress: Bacteria, fungi, plants and animals
Keywords: AHP1; alkylhydroperoxide reductase; AHR; aryl hydrocarbon receptor; ARE; antioxidant response element; 2CPA; 2-Cys peroxiredoxin-A; CRD; cysteine rich domain; Cul3; Cullin 3; DPH; diphenylhexatriene; EpRE; electrophile response element; ERK; extracellular
Old and new generation lipid mediators in acute inflammation and resolution
Keywords: 5-HT; 5-hydroxytryptamine; HETEs; hydroxyeicosatetraenoic acids; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5(S)-HPETE; hydroperoxyeicosatetranoic acid; 15R-HETE; 15-R-hydroxyeicosatetraenoic acid; 17R-HDHA; 17R-hydroxydocosahexaenoic acid; AA; arachidoni
TH17 cells mediate pulmonary collateral priming
Keywords: Asthma; IL-17A; TH cell; polysensitization; AHR; Airway hyperresponsiveness; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; KLH; Keyhole limpet hemocyanin; LN; Lymph node; mLN; Mediastinal lymph node; OVA; Ovalbumin; PMA; Phorbol 12-myristate
Asthma translational medicine: Report card
Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AP-1; activator protein 1; APC; antigen-presenting cell; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; CTLA-4; cytotoxic T lymphocyte-associated antigen
Species-specific activation of nuclear receptors correlates with the response of liver drug metabolizing enzymes to EMD 392949 in vitro
Keywords: AhR; arylhydrocarbon receptor; bp; base pair; DME; drug metabolizing enzyme; DMEM; Dulbecco's modified Eagle's medium; EMD; EMD 392949; FBS; fetal bovine serum; nt; nucleotide(s); NXR; nuclear xenobiotic receptor; P450; cytochrome P450-dependent monooxyge
A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico)
Keywords: Balaenoptera physalus; Skin biopsy; Mediterranean Sea; Gulf of California; OCs; PAHs; PBDEs; CYP1A1; CYP2B; HSP70; ERα; AHR; E2F-1;
Quercetin blocks caveolae-dependent pro-inflammatory responses induced by co-planar PCBs
Keywords: Quercetin; PCBs; Caveolae; AHR; CYP1A1; VCAM-1; MAPKs
Influence of the solvent quality on the AhR mediated Procept® assay measurement of dioxin and dioxin-like compounds
Keywords: Dioxin; Screening; AhR; Quantitative PCR; Solvent quality; Toluene;
Role of hormonal and environmental factors on early incidence of breast cancer in Iran
Keywords: Breast cancer; AhR; Breast fibroadenoma; Iran; Sex steroid hormones; ER; PgR
The activated aryl hydrocarbon receptor synergizes mitogen-induced murine liver hyperplasia
Keywords: AhR; Aryl hydrocarbon receptor; BrdU; bromodeoxyuridine; CKO; conditional knockout; CDK; cyclin-dependent kinase; PH; partial hepatectomy; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCPOBOP; 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene; TCPOBOP; TCDD; AhR;
Theoretical targets for TCDD: A bioinformatics approach
Keywords: AhR; Protein; Virtual screening; TarFisDock
Estrogenic and AhR activities in dissolved phase and suspended solids from wastewater treatment plants
Keywords: Suspended solids; Partitioning; Endocrine disruptors; ERα; AhR
Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction
Keywords: Flavonoid; AhR; TCDD; ERK; Phosphorylation
Allergic rhinitis as a predictor for wheezing onset in school-aged children
Keywords: Allergic rhinitis; birth cohort study; wheezing; allergic sensitization; risk factors; AHR; Airway hyperresponsiveness; MAS; German Multicentre Allergy Study; PARF; Population-attributable risk fraction; RR; Relative risk;
One-way inhibiting cross-talk between arylhydrocarbon receptor (AhR) and estrogen receptor (ER) signaling in primary cultures of rainbow trout hepatocytes
Keywords: AhR; ER; Fish; Hepatocytes; Aromatic hydrocarbons; Estrogens
Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: Different toxicity and target gene expression
Keywords: Flame retardants; PBDE; BDE47; Tetrabrominated dibenzofuran; AhR; Microarray analysis; Zebrafish
Indirubins deplete striatal monoamines in the Intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis
Keywords: 6BIO; 6-bromoindirubin-3â²-oxime; 5BIO; 5-bromoindirubin-3â²-oxime; 5A6BI; 5-amino-6-bromoindirubin; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin/5-hydroxytryptamine; AhR; aryl hydrocarbon receptor; BSA; bovine serum albumin; CDK; cyclin-dependen
Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines
Keywords: Cyp1a1; Cyp1b1; AhR; DNA methylation; Histone deacetylase
Ube2l3 gene expression is modulated by activation of the aryl hydrocarbon receptor: Implications for p53 ubiquitination
Keywords: AhR; Ubiquitin–proteasome system; Ube2l3; p53; TCDD
Beta tubulin affects the aryl hydrocarbon receptor function via an Arnt-mediated mechanism
Keywords: AhR; aryl hydrocarbon receptor; Arnt; Ah receptor nuclear translocator; HIF-1α; hypoxia inducible factor 1 alpha; βME; β-mercaptoethanol; DRE; dioxin response element; HRE; hypoxia response element; βNF; β-napthoflavone; HEDG; 25 mM HEPES, pH 7.4, 1
Differential transcription of genes involved in peroxisome proliferation in thicklip grey mullets Chelon labrosus injected with benzo(a)pyrene
Keywords: AOX1; palmitoyl-CoA oxidase; MFP; multifunctional protein; THIO; 3-ketoacyl-CoA thiolase; DECR; Î2,Î4-dienoyl-CoA reductase 2; PMP70; peroxisomal membrane protein of 70Â kDa; CAT; catalase; CYP1A; cytochrome P450 1A; PPAR; peroxisome proliferator activa
TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes
Keywords: VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; TSU-16; (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone; CYP; cytochrome P450; AhR; aryl hydrocarbon receptor; OMP; omeprazole; 3MC; 3-methylcholanthr
Molecular cloning and sequence analysis and the response of a aryl hydrocarbon receptor homologue gene in the clam Ruditapes philippinarum exposed to benzo(a)pyrene
Keywords: AhR; Benzo(a)pyrene; cDNA cloning; mRNA expression; Ruditapes philippinarum; Tissue-expression profile
2,3,7,8-Tetrachlorodibenzo-p-dioxin and β-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism
Keywords: H9c2 cells; TCDD; AhR; Cytochrome P450s; Heart; Hypertrophy
Effects of dioxin isomers on induction of AhRs and CYP1A1 in early developmental stage embryos of medaka (Oryzias latipes)
Keywords: Dioxin isomer; TEF; AhR; CYP1A1; Medaka; Embryo
IL-10 family of cytokines
Keywords: Psoriasis; Inflammatory bowel disease; RORgammaT; AHR; Interferon
Eczema in Early Life: Genetics, the Skin Barrier, and Lessons Learned from Birth Cohort Studies
Keywords: AhR; Aryl-hydrocarbon Receptor; ALSPAC; Avon Longitudinal Study of Parents and Children; BAMSE; Children, Allergy, Environment Stockholm Epidemiology; CCAAPS; Cincinnati Childhood Allergy and Air Pollution Study; CMA1; Mast cell chymase 1; COAST; Childhoo
Predictors of remitting, periodic, and persistent childhood asthma
Keywords: Remission; natural history; persistent asthma; AHR; Airway hyperresponsiveness; CAMP; Childhood Asthma Management Program; ED; Emergency department; FVC; Forced vital capacity; OR; Odds ratio;
A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma
Keywords: Medication adherence; inhaled corticosteroids; asthma; randomized controlled trial; aHR; Adjusted hazard ratio; aRR; Adjusted relative rate; HMO; Health maintenance organization; ICC; Intracluster correlation coefficient; ICS; Inhaled corticosteroid;
The role of the T cell in asthma
Keywords: T lymphocyte, TH2, cytokine, regulatory T cell, asthma, natural killer T cell, γδ T cell; AHR; Airways hyperresponsiveness; FoxP3; Forkhead box protein 3; NK; Natural killer; EB; Eosinophilic bronchitis; T-bet; T-box transcription factor; Treg; Regulato
Silymarin protects PBMC against B(a)P induced toxicity by replenishing redox status and modulating glutathione metabolizing enzymes-An in vitro study
Keywords: PAHs; Polycyclic aromatic hydrocarbons; B(a)P; Benzo(a)pyrene; QD; Quinone derivatives; ROS; Reactive oxygen species; LPO; Lipid peroxidation; PO; Protein oxidation; GSH; Reduced glutathione; GSSG; Oxidised glutathione; GR; Glutathione reductase; GPx; Glu
Biology of interleukin-10
Keywords: IL-10 family; Cytokine receptor; c-maf; AHR; Foxp3; IL-27