دانلود مقالات ISI درباره Akr1B10 + ترجمه فارسی

بهینه سازی ساختار مهارکننده های آلدو ایسیدیدید ردوکتاز مبتنی بر تتراهیدروپیریدیدول باعث بهبود کارایی و انتخاب آنها شد

Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity

Keywords: ALR2; aldose reductase; ALR1; aldehyde reductase; ARIs; aldose reductase inhibitors; AKR1B1; aldo-keto reductase family1 member1; AKR1B10; aldo-keto reductase family1 member10; Glc; glucose; Ep; epalrestat; Aldose reductase inhibition; Diabetic compli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

تحقیقاتی مقاله تغییرات مولکولی و متابولیک در فک های سلولی شکم کبد انسان شبیه تغییراتی است که در گوسفند وحشی

Research ArticleMolecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis

Keywords: ACAC; acetyl-coenzyme A carboxylase; ACADM; acyl-CoA dehydrogenase for acyl chains of medium length; ACLY; ATP citrate lyase; AKR1B10; aldo-keto reductase family 1, member B10; AKT; v-akt murine thymoma viral oncogene homolog; AMPK; AMP-activated kinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity

Keywords: Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Overexpression and enhanced specific activity of aldoketo reductases (AKR1B1 & AKR1B10) in human breast cancers

Keywords: Aldose reductase; AKR1B1; AKR1B10; Breast cancer; Chemoresistance; Tumor grade;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo

Keywords: Amentoflavone (PubChem CID: 5281600); Doxorubicin hydrochloride (PubChem CID: 443939); Epalrestat (PubChem CID: 1549120); AKR1B10; Amentoflavone; Anti-cancer; Combinatorial treatment; Doxorubicin; Selanginella tamariscina;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008

Keywords: Cancer; Enzyme inhibitor; Psoriasis; RAR/RXR agonist; Retinoic acid; Skin disease; AR; Aldose Reductase; AKR; Aldo-Keto Reductase; AKR1B10; AKR family member 1B10; AKR1B15; AKR family member 1B15; AKR1A1; AKR family member 1A1 or aldehyde reductase; ARIs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Design and synthesis of polyhydroxy steroids as selective inhibitors against AKR1B10 and molecular docking

Keywords: Synthesis; Polyhydroxy steroids; AKR1B10; Selective inhibitor; Anti-cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of aldo-keto reductase family 1 member B10 by unsaturated fatty acids

Keywords: Aldo-keto reductase; AKR1B10; cis-Unsaturated fatty acids; Cancer; Inhibitory selectivity; AKR; aldo-keto reductase; ALA; α-linolenic acid; ARA; arachidonic acid; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; LA; linoleic acid; ONE; 4-oxo-2-none

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease

Keywords: AKR1B10; aldo-keto reductase family 1, member B10; ALDH; aldehyde dehydrogenase; CRABP; cellular retinoic acid binding protein; CYP26; cytochrome P450, family 26; KD; keloid disease; KE; keloid epidermis; KF; keloid fibroblast; LCM; laser capture microdis

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism

Keywords: HMGB1; high-mobility group box 1; VILI; ventilator-induced lung injury; LVT; low tidal volume; HVT; high tidal volume; MLVEC; mouse lung vascular endothelial cell; VE-cadherin; vascular endothelial cadherin; DAMP; damage-associated molecular pattern; ROS;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of steroidal derivatives as selective inhibitors of AKR1B10

Keywords: Aldose reductase; AKR1B10; Inhibitors; Steroidal derivatives; Molecular docking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

AKR1B10, a good prognostic indicator in gastric cancer

Keywords: AKR1B10; Gastric cancer; Metastasis; Prognosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras-E-cadherin pathway

Keywords: AKR1B10; KRAS; E-cadherin; Migration; Invasion; Pancreatic adenocarcinoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Aldoketoreductase family 1B10 (AKR1B10) as a biomarker to distinguish hepatocellular carcinoma from benign liver lesions

Keywords: Hepatocellular carcinoma; Hepatic adenoma; Focal nodular hyperplasia; AKR1B10

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Combining metabolomic analysis and microarray gene expression analysis in the characterization of the medicinal plant Chelidonium majus L

Keywords: Chelidonii herba; Herbal safety; Gene expression profiling; 1H-NMR fingerprint; IPA; Ingenuity pathway analysis; PCA; Principal component analysis; qRT-PCR; quantitative real-time PCR; AhRR; Aryl-hydrocarbon receptor repressor; AKR1B10; Aldo-keto reductas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C3

Keywords: AKR1A1; aldo-keto reductase 1A1; AKR1B1; aldo-keto reductase 1B1; AKR1B10; aldo-keto reductase 1B10; AKR1C3; aldo-keto reductase 1C3; CBR1; carbonyl reductase 1; qRT-PCR; quantitative real-time reverse transcription PCR; UHPLC; ultra-high performance liqu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111)

Keywords: AKR1B10; aldo-keto reductase family1 member10; AKR1B1; aldose reductase aldo-keto reductase family1 member1; FLF; flufenamic acid; AKR1A1; aldehyde reductase; AKR1B10; AKR1B1; Inhibitor selectivity; Crystal structure;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleSUOX is a promising diagnostic and prognostic biomarker for hepatocellular carcinoma

Keywords: HCC; hepatocellular carcinoma; HBV; hepatitis B virus; DN; dysplastic nodules; HGDN; high-grade dysplastic nodules; WD-sHCC; well-differentiated small hepatocellular carcinoma; SUOX; sulfite oxidase; AKR1B10; aldo-ketoreductase family 1 member B10; MD-sHC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway

Keywords: Nrf2; nuclear factor erythroid 2-related factor 2; HCC; hepatocellular carcinoma; HO-1; heme oxygenase-1; Keap1; kelch-like ECH-associated protein 1; AKR1B10; Aldo-keto reductase 1B10; MRP5; multidrug resistance-associated protein 5; ADM; doxorubicin; D

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of proteomic signatures associated with lung cancer and COPD

Keywords: 2D-PAGE; Two dimensional electrophoresis; AKR1B10; Aldo-keto reductase family 1, member B10; AKR1C3; Aldo-keto reductase family 1, member C3; ALDH3A1; Aldehyde dehydrogenase 3 family, member A1; ALDOA; Aldolase A; AMY1A; Alpha 1 amylase; AMY2A; Alpha 2 am

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Decreased levels of AKR1B1 and AKR1B10 in cancerous endometrium compared to adjacent non-cancerous tissue

Keywords: AKR1B1; aldo-keto reductase 1B1; AKR1B10; aldo-keto reductase 1B10; Retinoic acid; Prostaglandins; Inflammation; Cancer; AKR1B;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

X-ray structure of the V301L aldo–keto reductase 1B10 complexed with NADP+ and the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity

Keywords: AKR1B10; Aldo–keto reductase; Aldose reductase; Diabetes; Enzyme inhibitor; Fidarestat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of rabbit aldose reductase-like protein with 3β-hydroxysteroid dehydrogenase activity

Keywords: AKR1B10; Aldo–keto reductase; Aldose reductase; 3β-Hydroxysteroid dehydrogenase; 4-Oxo-2-nonenal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A-class prostaglandins: Early findings and new perspectives for overcoming tumor chemoresistance

Keywords: Cyclopentenone; AKR1B10; GST; Chemoresistance; Prostaglandin A1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo–keto reductase 1B10

Keywords: AKR1B10; Aldose reductase; Caffeic acid phenethyl ester; Inhibitor; Selectivity; CancerAKR, Aldo–keto reductase; AKR1B1, Human aldose reductase; AKR1B10, A human member in the AKR1B subfamily of the AKR superfamily; CAPE, Caffeic acid phenethyl ester

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of aldo–keto reductase AKR1B10 gene expression: Involvement of transcription factor Nrf2

Keywords: AKR, aldo–keto reductase; ARE, antioxidant response elementAldo–keto reductase; AKR1B10; Nrf2; Promoter; Microsatellite; Ethoxyquin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10

Keywords: AKR; aldo-keto reductase; ALR; aldehyde reductase; AR; aldose reductase; FBS; fetal bovine serum; HNE; 4-hydroxy-2-nonenal; PHPC; (Z)-2-(phenylimino)-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide; AKR1B10; Aldose reductase-like protein; Aldose redu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleIdentification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours

Keywords: HCC; hepatocellular carcinoma; CC; cholangiocarcinoma; AFP; alpha-fetoprotein; AKR1B10; aldo-ketoreductase1-B10; RDA; representational difference analysis; PCR; polymerase chain reaction; RT-PCR; reverse transcriptase-polymerase chain reaction; TMA; tis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Properties and tissue distribution of a novel aldo–keto reductase encoding in a rat gene (Akr1b10)

Keywords: Aldo–keto reductase superfamily; AKR1B10; Aldose reductase; Glycation; Oxidative stress; 4-Oxo-2-nonenal; 4-Hydroxy-2-nonenal; 3-Deoxyglucosone

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Cancer biomarker AKR1B10 and carbonyl metabolism

Keywords: Aldo-keto reductase; AKR1B10; Cancer; Chemotherapy; Inhibitor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: Probing the active site of the enzyme with molecular modeling and site-directed mutagenesis

Keywords: AKR1B10; Aldose reductase-like 1; Aldose reductase; Curcumin; Bisdemethoxycurcumin; Polyphenol;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Acetyl-CoA carboxylase-α inhibitor TOFA induces human cancer cell apoptosis

Keywords: ACCA; acetyl-CoA carboxylase-α; ACCB; acetyl-CoA carboxylase-β; AKR1B10; aldo-keto reductase family 1 B10; BC; biotin carboxylase; CPT-1; carnitine palmitoyltransferase 1; CT; carboxyltransferase; FAS; fatty acid synthetase; PARP; Poly (ADP-ribose) po

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Role of human aldo-keto-reductase AKR1B10 in the protection against toxic aldehydes

Keywords: DEPT; distortionless enhancement by polarization transfer; 4-HNE; (2E)-4-hydroxynon-2-enal; HPLC; high-pressure liquid chromatography; 4-MP; 4-methylpentanal; 4-ONE; (2E)-4-oxonon-2-enal; TLC; thin layer chromatography; TMS; tetramethylsilane; Aldo-keto

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibition of aldose reductase by dietary antioxidant curcumin: Mechanism of inhibition, specificity and significance

Keywords: AKR; aldo-keto reductase; ALR1; aldehyde reductase; ALR2, AKR1B1; human aldose reductase; HSIR, AKR1B10; human small intestine reductase; ARI; aldose reductase inhibitor; RBC; red blood cells; Aldo-keto reductase; ALR2; AKR1B10; Curcumin; Sorbitol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Kinetic studies of AKR1B10, human aldose reductase-like protein: Endogenous substrates and inhibition by steroids

Keywords: Aldo–keto reductase superfamily; AKR1B10; Aldose reductase-like 1; Aldose reductase; 20α-Hydroxysteroid dehydrogenase; Isoprenoid; Steroid hormone; Bile acid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers

Keywords: AKR1B10; Fenofibrate; Cancer; Liver; Lung

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

AKR1B10 in usual interstitial pneumonia: Expression in squamous metaplasia in association with smoking and lung cancer

Keywords: Usual interstitial pneumonia/idiopathic pulmonary fibrosis (UIP/IPF); AKR1B10; Lung cancer; Squamous metaplasia; Tobacco smoking

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه