Keywords: عامل آلکیل کردن; alkylant; antimétabolite; inhibiteur de topoisomérase; poison du fuseau; alkylating agent; antimetabolite; spindle poison; topoisomerase inhibitor;
مقالات ISI عامل آلکیل کردن (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Design, synthesis, chemical and biological evaluation of brain targeted alkylating agent using reversible redox prodrug approach
Keywords: عامل آلکیل کردن; Alkylating agent; Blood-brain barrier; Redox system; ADME; NBP assay; Biological oxidation;
Keywords: عامل آلکیل کردن; POPAM, 3-(4-(bis(2-chloroethyl)amino)phenoxy)propanoic acid; l-PAM, l-phenylalanine mustardSteroidal lactam; Antileukemic agent; Nitrogen mustard; Alkylating agent; Homo-aza-steroidal alkylators
Keywords: عامل آلکیل کردن; Alkylating agent; Blood–brain barrier; Physico-chemical parameters; NBP assay; Kinetic study
Keywords: عامل آلکیل کردن; Neuroblastoma; meta-Iodobenzylguanidine (mIBG); Alkylating agent; Busulfan
Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA
Keywords: عامل آلکیل کردن; Duocarmycins; Tafuramycin A; Cytotoxic; Antimalarial; Vaccine; Minor groove; Adenine-N3; Alkylating agent;
Original ResearchDigital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients
Keywords: عامل آلکیل کردن; MGMT; Immunohistochemistry; DNA methylation; Digital PCR; Metastatic colorectal cancer; Alkylating agent;
L-β-N-methylamino-l-alanine (BMAA) nitrosation generates a cytotoxic DNA damaging alkylating agent: An unexplored mechanism for neurodegenerative disease
Keywords: عامل آلکیل کردن; BMAA; ALS; Alkylating agent; N-nitrosation;
Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: Secondary analysis of the Euro-Ewing99-R1 trial
Keywords: عامل آلکیل کردن; Ewing sarcomas; Alkylating agent; Gender; Efficacy; Toxicity; Interaction; Metabolism; Constitutive androstane receptor; CYP3A4; CYP2B6;
Trial of a 5-day dosing regimen of temozolomide in patients with relapsed small cell lung cancers with assessment of methylguanine-DNA methyltransferase
Keywords: عامل آلکیل کردن; Temozolomide; SCLC; MGMT; Biomarker; Alkylating agent; Chemotherapy;
Clerocidin-mediated DNA footprinting discriminates among different G-quadruplex conformations and detects tetraplex folding in a duplex environment
Keywords: عامل آلکیل کردن; G-quadruplex; Clerocidin; Footprinting; Protection assay; Alkylating agent; DNA conformation;
AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents
Keywords: عامل آلکیل کردن; Autophagy; AMPK; Alkylating agent; DNA damage; PARP-1; Necrosis
Antigen and Lymphopenia-Driven Donor T Cells Are Differentially Diminished by Post-Transplantation Administration of Cyclophosphamide after Hematopoietic Cell Transplantation
Keywords: عامل آلکیل کردن; Allogeneic-hematopoietic stem cell transplantation (HSCT); Graft-versus-host disease (GVHD); Lymphopenia-induced proliferation; Alkylating agent; Post-transplantation cyclophosphamide; Myeloablative conditioning
Determination of tissue distribution of potent antitumor agent ureidomustin (BO-1055) by HPLC and its pharmacokinetic application in rats
Keywords: عامل آلکیل کردن; Alkylating agent; Bioassay; Organ distribution; Pharmacokinetics
Diepoxybutane interstrand cross-links induce DNA bending
Keywords: عامل آلکیل کردن; DNA cross-linking; Diepoxybutane; DNA bending; DNA damage; Alkylating agent;
Development and validation of LC–MS/MS assays for the quantification of bendamustine and its metabolites in human plasma and urine
Keywords: عامل آلکیل کردن; Bendamustine; Metabolites; Alkylating agent; Stability; LC–MS/MS
Sulfur mustard induced oxidative stress and its alteration by epigallocatechin gallate
Keywords: عامل آلکیل کردن; EGCG; Green tea; Antioxidant; Alkylating agent; Apoptosis; Glutathione; Chemical warfare
Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation
Keywords: عامل آلکیل کردن; PI polyamide; Alkylating agent; PEGylation; Minor groove binder; Antitumor agent
Decreased fertility among female childhood cancer survivors who received 22-27 Gy hypothalamic/pituitary irradiation: a report from the Childhood Cancer Survivor Study
Keywords: عامل آلکیل کردن; Childhood cancer survivor; hypothalamic irradiation; pituitary irradiation; alkylating agent; pregnancy;
Tumor prevalence and biomarkers of genotoxicity in brown bullhead (Ameiurus nebulosus) in Chesapeake Bay tributaries
Keywords: عامل آلکیل کردن; Biomarker; Brown bullhead; DNA adduct; PAH; Tumor; Alkylating agent
Lung Carcinogenicity of Sulfur Mustard
Keywords: عامل آلکیل کردن; Alkylating agent; Chemical weaponry; Chronic obstructive pulmonary disease; Mustard lung; p53
Accumulation of true single strand breaks and AP sites in base excision repair deficient cells
Keywords: عامل آلکیل کردن; Alkylating agent; AP sites; Base excision repair; Single strand breaks; O-hydroxylamine
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphomas, and Multiple Myeloma: Treatment Recommendations From an International Consensus Panel
Keywords: عامل آلکیل کردن; Alkylating agent; Non-Hodgkin's lymphoma; Phase I trial; Refractory; Relapsed; Rituximab
Comparative analysis of DNA alkylation by conjugates between pyrrole–imidazole hairpin polyamides and chlorambucil or seco-CBI
Keywords: عامل آلکیل کردن; Alkylating agent; Minor groove binder; DNA alkylation; Antitumor agent; Pyrrole imidazole polyamide
Recombination kinetics of polarons in films of alkylator-sensing co-polymers
Keywords: عامل آلکیل کردن; Alkylating agent; Conjugated polymer; Polaron
Vapor phase alkylation of indole with methanol and dimethylcarbonate over Ni–Mn based ferrospinels
Keywords: عامل آلکیل کردن; Alkylation; Alkylating agent; Ferrospinel; Indole; 3-Methylindole
EMS in Viracept—Initial (‘traditional’) assessment of risk to patients based on linear dose response relations
Keywords: عامل آلکیل کردن; In vivo genotoxicity; Cancer; Birth defects; Risk assessment; Alkylating agent; Genotoxic impurity
Vapor phase alkylation of pyrrole with methanol and dimethylcarbonate over ferrospinels
Keywords: عامل آلکیل کردن; Alkylation; Alkylating agent; Ferrospinels; Pyrrole; 2-Methylpyrrole
Quantitative PCR analysis of diepoxybutane and epihalohydrin damage to nuclear versus mitochondrial DNA
Keywords: عامل آلکیل کردن; Diepoxybutane; Quantitative PCR; DNA damage; Cytotoxicity; Alkylating agent; Apoptosis
Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS
Keywords: عامل آلکیل کردن; Alkylating agent; N7-methylguanine; AP sites; Base excision repair; Single strand breaks; PARP-1;
Collision induced dissociation of protonated N-nitrosodimethylamine by ion trap mass spectrometry: Ultimate carcinogens in gas phase
Keywords: عامل آلکیل کردن; N-nitrosodimethylamine; CID; Methanediazonium ion; Alkylating agent; Ion/molecule reactions;
Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
Keywords: عامل آلکیل کردن; Vesicant; Sulfur mustard; Microarray; Alkylating agent; Skin; MMP inhibitor; MMP; Matrix metalloproteinase;
Literature review on the genotoxicity, reproductive toxicity, and carcinogenicity of ethyl methanesulfonate
Keywords: عامل آلکیل کردن; Literature review; Alkylating agent; Dose-response; Genotoxic impurity; Risk assessment
Spectroscopic studies of STZ-induced methylated-DNA in both in vivo and in vitro conditions
Keywords: عامل آلکیل کردن; Alkylating agent; DNA; Streptozotocin; DNA structural change; DNA function;
Alkyltransferase-like proteins
Keywords: عامل آلکیل کردن; O6-Alkylguanine; Alkylating agent; DNA alkylation; AGT; MNNG; Epistasis
Kinetic investigation on aqueous decomposition of 2-chloroethylnitrososulfamide
Keywords: عامل آلکیل کردن; 2-Chloroethylnitrososulfamide; Alkylating agent; Anticancerous compounds; Kinetic decomposition; LC–MS; UV spectroscopy
Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage tolerance
Keywords: عامل آلکیل کردن; Alkylating agent; Methylnitrosourea; cII; Lambda shuttle vector; PMS2; Mismatch repair (MMR)
Induced endoplasmic reticulum (ER) stress and binding of over-expressed ER specific chaperone GRP78/BiP with dimerized epidermal growth factor receptor in mammalian cells exposed to low concentration of N-methyl-N′-nitro-N-nitrosoguanidine
Keywords: عامل آلکیل کردن; Epidermal growth factor receptor; Endoplasmic reticulum stress/unfolded protein responses; Alkylating agent; N-Methyl-N′-nitro-N-nitrosoguanidine; Endoplastic reticulum stress; Caspases-12; Glucose-regulated protein 78; GADD153/CHOP
Use of 2-mercaptopyridine for the determination of alkylating agents in complex matrices: application to dimethyl sulfate
Keywords: عامل آلکیل کردن; Dimethyl sulfate; 2-Mercaptopyridine; Alkylating agent; Reversed-phase liquid chromatography; Fluorescence;
Development and validation of a sensitive GC-MS method for the determination of trace levels of an alkylating reagent in a β-lactam active pharmaceutical ingredient
Keywords: عامل آلکیل کردن; GC-MS; Selected ion monitoring; Alkylating agent; Trace assays; Active pharmaceutical ingredient;
N-methyl-Nâ²-nitro-N-nitrosoguanidine interferes with the epidermal growth factor receptor-mediated signaling pathway
Keywords: عامل آلکیل کردن; Epidermal growth factor receptor; Ras; Signal transduction pathway; Alkylating agent;