Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AAV, adeno-associated virus; AAV2, adeno-associated viral vector serotype 2; AMD, age-related macular degeneration; iPSC, induced pluripotent stem cell; RP, retinitis pigmentosa; RPE, retinal pigment epithelium; VEGF, vascular endothelial growth factor
مقالات ISI AMD، دژنراسیون ماکولا مربوط به سن (ترجمه نشده)
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Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AHR, aryl hydrocarbon receptor; Aldh3a1, aldehyde dehydrogenase 3A1; AMD, age-related macular degeneration; BHQ, black-hole quencher; CYP1A1, cytochrome P450 1A1; CYP1A2, cytochrome P450 1A2; CYP1B1, cytochrome P450 1B1; FAM, 6-carboxyfluorescein; Gsr, gl
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; CC3, complement component 3; AMD, age-related macular degeneration; OR, odds ratio; SNP, single nucleotide polymorphism; CI, confidence interval; RPE, retinal pigment epithelium; CNV, choroidal neovascularization; PB, population-based; HB, hospital-based;
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AAV, adeno-associated viral vector; AMD, age-related macular degeneration; ANOVA, analysis of variance; DAPI, 4′,6-diamidino-2-phenylindole; ELISA, enzyme-linked immunosorbent assay; GO, Gene Ontology; ONH, optic nerve head; ONL, outer nuclear layer; OS,
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; AREDS, Age-Related Eye Disease Study; DR, diabetic retinopathy; GDP, gross domestic product; ICER, incremental cost-effectiveness ratio; QALY, quality-adjusted life year; STDR, sight-threatening diabetic retinopathy;
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Buttermilk; Egg yolk; Cholesterol; Serum lipids; Milk polar lipids; Lutein; ZeaxanthinALAT, alanine transaminase; ALP, alkaline phosphatase; AMD, age-related macular degeneration; ANOVA, analysis of variance; Apo A1, apolipoprotein A1; Apo B100, apolipopr
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; ERG, electroretinogram; hBM-MSCs, human bone marrow mesenchymal stem cells; ONL, outer nuclear layer; PFA, paraformaldehyde; RCS, royal college surgeons; RP, retinitis pigmentosa; RPE, retinal pigment epitheliumEpire
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; CI, confidence interval; D, diopter; OR, odds ratio; SE, spherical equivalent; US, United States; VA, visual acuity; WHO, World Health Organization
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ADH, adipic dihydrazide; AMD, age-related macular degeneration; cmax, maximum plasma concentration; EDC, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; EGF, epidermal growth factor; ESHU, poly(ethylene glycol)-poly-(serinol hexamethylene urethane); HA, hy
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; RPE, retinal pigmented epithelium; CNV, choroidal neovascularization; VEGF, vascular endothelial growth factor; IgG, immunoglobulin γ; Fab, antigen binding fragment; FDA, Food and Drug Administration; EDTRS, early tr
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ADSCs, adipose-derived stem cells; AMD, age-related macular degeneration; BDNF, brain-derived neurotrophic factor; BMSCs, bone marrow-derived stem cells; CNS, central nervous system; CNTF, ciliary neurotrophic factor; DPSC, dental pulp stem cells; EGF, ep
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ACE, angiotensin-I converting enzyme; AGT, angiotensinogen; AGTR1, angiotensin II type 1 receptor; AGEs, advanced glycation end-products; AMD, age-related macular degeneration; AR2, aldose reductase; ARPE, arising retinal pigment epithelia; BRB, blood–ret
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Endoplasmic reticulum stress; Unfolded protein response; Retina; Angiogenesis; VEGF; Endothelial cellsAhR, aryl hydrocarbon receptor; AMD, age-related macular degeneration; ATF, activating transcription factor; Bip, immunoglobulin heavy chain-binding prot
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; DVA, distance visual acuity; IVI, Impact of Vision Impairment; NEI-VFQ-25, National Eye Institute Visual Functioning Questionnaire 25 items; OCT, optical coherence tomography; QoL, quality of life; SD, standard devia
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; CI, confidence interval; DM, diabetes mellitus; HRS, Health and Retirement Study; IADL, instrumental activity of daily living; ICD-9-CM, International Classification of Diseases, 9th Revision, Clinical Modification;
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; BEST1, bestrophin 1; bFGF, basic fibroblast growth factor; ECM, extracellular matrix; FACS, fluorescent-activated cell sorting; FGF, fibroblast growth factor; hESC, human embryonic stem cell; hiPSC, human induced plu
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; RPE, retinal pigment epithelium; nvAMD, neovascular age-related macular degeneration; VEGF, vascular endothelial growth factor; HtrA1, heat temperature required factor A; IL, interleukin; TNF, tumour necrosis factor;
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ADC, Antibody-drug conjugates; ADCC, Antibody-dependent cellular cytotoxicity; AMD, Age-related macular degeneration; bFGF, basic Fibroblast Growth Factor; CDC, Complement dependent cytotoxicity; CDR, Complementarity determining region; CNS, Central Nervo
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Eye; Ocular; Glaucoma; Retina; Renin–angiotensin system; Angiotensin IIAGEs, Advanced glycation endproducts; AMD, Age-related macular degeneration; Ang, Angiotensin; ACE, Angiotensin converting enzyme; ARB, Angiotensin receptor blocker; AGT, Angiotensinog
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Retinal remodeling; Neurodegeneration; Glial cells; Retinal therapy; Neuroprotection; Retinal diseasesAAV, Adeno-associated virus; AGEs, Advanced glycation end products; AMD, Age-related macular degeneration; Apaf-1, Apoptotic protease-activating factor-1
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ADR, adriamycin; AMD, age-related macular degeneration; ATP, adenosine triphosphate; CNV, choroidal neovascularisation; DIO, diosmetin; H&E, hematoxylin and eosin; IC50, inhibition for 50% of the cells; IVI, intravitreal injection; PVR, proliferative vitr
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Akt, serine/threonine-specific protein kinase; AMD, age-related macular degeneration; CF, cystic fibrosis; COPD, chronic obstructive pulmonary disease; c-Src, proto-oncogene tyrosine-protein kinase; EC, endothelial cell; FGF-2, fibroblast growth factor-2;
Rapid isolation of pure Complement Factor H from serum for functional studies by the use of a monoclonal antibody that discriminates FH from all the other isoforms
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AP, alternative pathway; aHUS, atypical haemolytic uraemic syndrome; AMD, age-related macular degeneration; BCIP, 5-bromo-4-chloro-3-indolyl-phosphate; CCP, complement control protein; CFH, Complement Factor H gene; DAA, decay acceleration activity; FB, c
The role of heparan sulfate as determining pathogenic factor in complement factor H-associated diseases
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; FH, complement factor H; HS, heparan sulfate; AP, alternative pathway; CCP, complement control protein domain; GAG, glycosaminoglycan; AMD, age-related macular degeneration; DDD, dense deposit disease; aHUS, atypical hemolytic uremic syndrome; dpX, degree
Associations of the G1961E and D2177N variants in ABCA4 and the risk of age-related macular degeneration
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ABCA4, ATP-binding cassette, sub-family A, member 4; ABC, ATP-binding cassette; A2E, N-retinyl-N-retinylidene ethanolamine; AMD, age-related macular degeneration; AREDS, Age-Related Eye Disease Study; CI, confidence interval; DGGE, denaturing gradient gel
Beneficial protective effect of pramipexole on light-induced retinal damage in mice
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Age-related macular degeneration; Light-induced retinal damage; Apoptosis; Pramipexole; Antioxidant4-HNE, 4-hydroxynonenal; 8OHdG, 8-hydroxy-2-deoxyguanosine; ALS, amyotrophic lateral sclerosis; AMD, age-related macular degeneration; AREDS, age-related ey
Retinal gene delivery by adeno-associated virus (AAV) vectors: Strategies and applications
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AAV, adeno-associated virus; AMD, age-related macular degeneration; ChR2, channelrhodopsin 2; CNG, cyclic nucleotide-gated channel; CNTF, ciliary neurotrophic factor; GDNF, glial cell derived neurotrophic factor; GFP, green fluorescent protein; ITR, inver
Nanoparticles for the treatment of ocular neovascularizations
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AGEs, advanced glycosylation end products; AMD, age-related macular degeneration; AuNP, gold nanoparticles; BAB, blood-aqueous barrier; BM, Bruch’s membrane; BRB, blood-retinal barrier; CNV, choroidal neovascularization; DHA, docosahexaenoic acid; DR, dia
Light-induced disulfide dimerization of recoverin under ex vivo and in vivo conditions
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; rOx, reactive oxygen species; NO, nitric oxide; CH, choroid; RPE, retinal pigment epithelium; PL, photoreceptor layer; ONL, outer nuclear layer; INL, inner nuclear layer; GL, ganglion cell layer; NFL, nerve fiber lay
Fluorescence lifetime imaging (FLIM): Basic concepts and some recent developments
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ADC, analogue-to-digital converter; AFM, atomic force microscopy; AMD, age-related macular degeneration; APD, avalanche photodiode; CARS, coherent anti-Stokes Raman scattering; CCD, charge-coupled device; CFD, constant fraction discriminator; CFP, cyan/ce
Association between complement factor H Val62Ile polymorphism and age-related macular degeneration susceptibility: A meta-analysis
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; CFH, complement factor H; AMD, age-related macular degeneration; PCR, polymerase chain reaction; HWE, Hardy–Weinberg equilibrium; CI, confidence interval; OR, odds ratioAge-related macular degeneration; Complement factor H polymorphism; Meta-analysis
Therapeutic potentials of gene silencing by RNA interference: Principles, challenges, and new strategies
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AAV, adenovirus-associated vectors; AGO, argonaute; AGT, angiotensinogen; AMD, age-related macular degeneration; APP, amyloid precursor protein; AV, adenovirus vectors; BACE1, β-site APP cleavage enzyme 1; bFGF, basic fibroblast growth factor; CCR5RZ, T c
Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AD, Alzheimer’s disease; AMD, age-related macular degeneration; ANOVA, analysis of variation; BODIPY, boron-dipyrromethene; cAMP, cyclic adenosine monophosphate; EDTA, ethylenediaminetetraacetic acid; fAD, familial Alzheimer’s disease; GAPDH, glyceraldehy
Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AGEs; Angiogenesis; Anti-glycating agents; Blood-retinal barrier; Eye disease; InflammationAGEs, advanced glycation end products; ALEs, advanced lipoxidation end products; AP-1, activating protein-1; AMD, age-related macular degeneration; ARB, angiotensin
The β-adrenergic system as a possible new target for pharmacologic treatment of neovascular retinal diseases
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Angiogenesis; Neuroprotection; Oxygen-induced retinopathy model; β-AR blockade; β1/β2-AR knock-out mice; Preterm infantsAC, adenylyl cyclase; AMD, age-related macular degeneration; ARs, adrenergic receptors; BDNF, brain-derived neurotrophic factor; DBH, d
Channelrhodopsins—Their potential in gene therapy for neurological disorders
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AAV, adeno-associated virus; AMD, age-related macular degeneration; ArchT, archaerhodopsin-T from Halorubrum strain TP009; ChR, channelrhodopsin; ChR1, channelrhodopsin-1; ChR2, channelrhodopsin-2; ChRFR, ChR-fast receiver; ChRWR, ChR-wide receiver; ChRGR
NAD+ maintenance attenuates light induced photoreceptor degeneration
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; rat; mouse; sirtuin; NMNAT1TPEN, N,N,N′N′-tetrakis(−)[2-pyridylmethyl]-ethylenediamine; NAD+, Nicotinamide adenine dinucleotide; NMNAT1, Nicotinamide mononucleotide adenyl-transferase-1; LD, light damage; AMD, Age-related macular degeneration; PARP1, Poly
Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; TLR3, toll-like receptor 3; RPE, retinal pigmented epithelium; Poly(I:C), polyinosinic:polycytidylic acid; AMD, age-related macular degeneration; STAT3, signal transducer and activator of transcription 3Toll-like receptor 3; Retinal pigmented epithelium;
Quantitative proteomics of aqueous and vitreous fluid from patients with idiopathic epiretinal membranes
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; epiretinal membranes; ocular fluids; mass spectrometry; quantitative proteomicsAF, aqueous fluid; AMD, age-related macular degeneration; AQUA, absolute quantitation; DR, diabetic retinopathy; ELISA, enzyme-linked immunosorbent assay; GO, gene ontology; HC
Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; A2-E, N-retinylidene- N-retinylethanol-amine; AGE, advanced glycation end products; AIM2, Absent in melanoma; AMD, age-related macular degeneration; Aβ, amyloid β; ATP, adenosine tri-phosphate; BACE1, β-secretase; BMDM, bone-marrow derived macrophages; Bm
CD46: The ‘multitasker’ of complement proteins
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; ADAM, a disintegrin and metalloproteinase; AP-1, activator protein 1; aHUS, atypical hemolytic uremic syndrome; AMD, age-related macular degeneration; Bcl-2, B-cell lymphoma 2; CCL, chemokine (C-C motif) ligand; CCP, complement control protein domain; CSL
HtrA1 is induced by oxidative stress and enhances cell senescence through p38 MAPK pathway
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; HtrA1; age-related macular degeneration; AMD; p38 MAPK; retinal pigment epithelium; senescence; oxidative stressHtrA1, High Temperature Requirement A1; AMD, age-related macular degeneration; TGF-β, transform growth factor -beta; MAPK, mitogen-activated pr
Elevated amyloid β production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid β in age-related macular degeneration
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Aβ, amyloid β; APP, amyloid precursor protein; RPE, retinal pigment epithelium; AMD, age-related macular degeneration; AD, Alzheimer’s disease; NEP, neprilysin; BACE, beta-site amyloid precursor protein cleaving enzymeAmyloid β; Retinal pigment epithelium
Ocular hazards of blue-light therapy in dermatology
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; age-related macular degeneration; blue light; blue-light phototherapy; photodynamic therapy; phototherapy; retinopathyALA, aminolevulinic acid; AMD, age-related macular degeneration; PDT, photodynamic therapy; RPE, retinal pigmented epithelium
Cholesterol enhances amyloid β deposition in mouse retina by modulating the activities of Aβ-regulating enzymes in retinal pigment epithelial cells
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; Aβ, amyloid β; APP, amyloid precursor protein; RPE, retinal pigment epithelium; AMD, age-related macular degeneration; AD, Alzheimer’s disease; NEP, neprilysinAmyloid β; Retinal pigment epithelium; Age-related macular degeneration; Cholesterol; Neprilysin
Stability and bioavailability of lutein ester supplements from Tagetes flower prepared under food processing conditions
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; BHT, butylated hydroxy toluene; β-lg, β-lactoglobulin; LE, lutein esters; MCT, medium chain triglycerides; O/W, oil/water; T, Tagetes; UV, ultravioletTagetes; Lutein ester; Emulsion; Stability; Whey protein; Bioavail
Manipulating the mediator: Modulation of the alternative complement pathway C3 convertase in health, disease and therapy
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; AP, alternative pathway; CA, cofactor activity; CCP, complement control protein domain; CP, classical pathway; CR1, complement receptor 1; CR2, complement receptor 2; CRIg, complement receptor of the immunoglobulin s
Serum autoantibody biomarkers for age-related macular degeneration and possible regulators of neovascularization
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AEC, 3-amino-9-ethylcarbazole; AMD, age-related macular degeneration; APS, antiphospholipid syndrome; AUC, area under the ROC curve; CEP, carboxyethylpyrrole; CNPase, cyclic nucleotide phosphodiesterase; CNV, choroidal neovascularization; DM, dermatomyosi
Microphthalmia-associated transcription factor acts through PEDF to regulate RPE cell migration
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; BDNF, brain-derived growth factor; cDNA, complementary DNA; EGFP, enhanced green fluorescent protein; FBS, fetal bovine serum; FGF, fibroblast growth factors; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; MITF, mi
Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin
Keywords: AMD، دژنراسیون ماکولا مربوط به سن; AMD, age-related macular degeneration; CSB, cytoskeleton stabilization buffer; ERG, electroretinography; HNE, 4-hydroxynonenal; PFA, paraformaldehyde; POS, shed photoreceptor outer segment tips; RPE, retinal pigment epithelium; TLC, thin-layer chromatogra