Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity
Keywords: آنتراسن 9-کربوکسیلیک اسید; Sodium channel; Use-dependence; Myotonia; Membrane hyperexcitability; Tocainide derivative; Mexiletine; TRR; time of righting reflex; 9-AC; anthracene-9-carboxylic acid; SAR; structure-activity relationship;