Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Cancer; Personalized medicine; Tumour microenvironment; Immunobiology; Targeted therapy; Pharmacogenetics; SmPC (alias SPC); summary of product characteristics; IBD; inflammatory bowel disease; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; com
مقالات ISI آنتی بادی-وابسته به سلول، سمیت سلولی (ترجمه نشده)
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Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; AIH-2; autoimmune hepatitis; Treg; regulatory T cells; NK; natural killer; TRAIL; tumor necrosis factor-related apoptosis inducing ligand; GITR; glucocorticoid-induced tumor necrosis factor-related receptor; IFNγ; interferon gamma; IL2; interleukin 2;
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; 5-FU; 5-fluoro-uracil; AAV; adeno-associated virus; ADAM; ADAM metallopeptidase domain; ADCC; antibody-dependent cell-mediated cytotoxicity; CCL; chemokine (C-C motif) ligand; CD; cluster of differentiation; CTLA-4; cytotoxic T-lymphocyte-associated ant
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Recombinant therapeutics; Aggregation; Host cell proteins; Glycosylation; Regulation; Biopharmaceuticals; 2D-PAGE; Two-dimensional polyacrylamide gel electrophoresis; ADCC; antibody-dependent cell-mediated cytotoxicity; AUC/SV-AUC; (Sedimentation velocity
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; ASC; antibody secreting cell; AHR; airway hyperresponsiveness; βc; common β; BCGF; B cell growth factor; BCDF; B cell differentiation factor; BCL1; murine chronic B leukemia; Btk; Bruton's tyrosine
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; AKT; protein kinase B; ATP; adenosine triphosphate; cfDNA; circulating free DNA; CISH; chromogenic in-situ hybridization; CTC; circulating tumor cells; EGFR; epithelial growth factor receptor; EMT; epit
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ABC; antibody-biologic conjugate; ADC; antibody-drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; ALL; acute lymphoblastic leukemia; ANC; antibody-nanoparticle conjugate; BBB; blood brain barrier; BiTE; bispecific T cell engager; CDC; c
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ACQ-5; Asthma Control Questionnaire-5; ACQ-6; Asthma Control Questionnaire-6; ADCC; antibody-dependent cell-mediated cytotoxicity; AG; antigen; AHR; airway hyper-responsiveness; AQLQ; Asthma Quality of Life Questionnaire; B; B cell; Bas; basophil; BrOâ;
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; AP3; adaptor protein 3; CHS; Chediak-Higashi syndrome; CMV; cytomegalovirus; CNKD; classical natural killer cell deficiency; CrkL; chicken tumor virus number 10 regulator of kinase-like; CTL; cytotoxi
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ABC; ATP binding cassette; ADCC; antibody-dependent cell-mediated cytotoxicity; ALDH; aldehyde dehydrogenase; CBP; cAMP response element binding protein (CREB)-binding protein; CSC; cancer stem cell; CTC; circulating tumour cell; DAPT; N-[N-(3,5-difluorop
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; ADCP; antibody-dependent phagocytosis; ELISA; enzyme-linked immunoabsorbant assay; gluV8; glutamyl endopeptidase I; IdeS; immunoglobulin G-degrading enzyme of str
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; AbX; antibody with mostly fucosylated glycans; AbX-AF; antibody with completely afucosylated glycans; ADCC; antibody-dependent cell-mediated cytotoxicity; AICC; antibody-independent cell-mediated cytotoxicity; CV; coefficient of variation; EC50; half maxi
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; PBMCs; peripheral blood mononuclear cells; NK; natural killer cells; IL; interleukin; ADCC; antibody-dependent cell-mediated cytotoxicity; FITC; fluorescein isothiacyanate; APC; allophycocyanin; PE; phycoerythrin; PC5; Phycoerythrincyanin 5; mAbs; monoclo
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Animal extrapolation; Preclinical studies; Experimental organism; Prediction; Mechanistic thinking; Ab; Antibody; ADCC; Antibody-Dependent Cell-Mediated Cytotoxicity; ADME; Absorption, Distribution, Metabolism, Excretion; CDC; Complement-Dependent Cytotox
Report on eighth WHO meeting on development of influenza vaccines that induce broadly protective and long-lasting immune responses: Chicago, USA, 23-24 August 2016
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Influenza; Pandemic influenza vaccine; Seasonal influenza vaccine; Universal influenza vaccine; Vaccine development; Nextgeneration influenza vaccine; ADCC; Antibody-dependent cell-mediated cytotoxicity; AE; Adverse event; CMI; cell-mediated immunity; CON
Transitioning from first- to second-generation biosimilars: An appraisal of regulatory and post-marketing challenges
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ACR; American College of Rheumatology; ADAb; anti-drug antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; AIFA; Italian Medicines Agency; CDC; complement-dependent cytotoxicity; CHMP; Committee for Medicinal Products for Human Use; DAS28; 28-j
Glycosimilarity assessment of biotherapeutics 1: Quantitative comparison of the N-glycosylation of the innovator and a biosimilar version of etanercept
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; APTS; 8-aminopyrene-1,3,6-trisulfonic acid; CGE-LIF; capillary gel electrophoresis - laser induced fluorescence; CQA; critical quality attributes; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; Fc; fragment
Dysregulated Response of Follicular Helper T Cells to Hepatitis B Surface Antigen Promotes HBV Persistence in Mice and Associates With Outcomes of Patients
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Viral Hepatitis; Immune Regulation; Neutralizing Antibody Response; Immunotherapy; ADCC; antibody-dependent cell-mediated cytotoxicity; anti-HBs; antibodies specific for hepatitis B surface antigen; ASC; antibody-secreting cell; CHB; chronic hepatitis B;
Large-scale expansion of Vγ9Vδ2 T cells with engineered K562 feeder cells in G-Rex vessels and their use as chimeric antigen receptor-modified effector cells
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; antibody-dependent cell-mediated cytotoxicity; artificial antigen-presenting cells; chimeric antigen receptor; gamma delta T cells;
Understanding the biology of HER3 receptor as a therapeutic target in human cancer
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Ab; antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; FDA; Food and Drug Administration; HER; Human epidermal growth factor receptor; HRG; heregulin; IGF-1R; insu
An improved method to quantify human NK cell-mediated antibody-dependent cell-mediated cytotoxicity (ADCC) per IgG FcR-positive NK cell without purification of NK cells
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; CD16A; cluster of differentiation designation for the Fc-gamma type III low affinity receptor for IgG, found on NK cells; CD20; cluster of differentiation designation for a B cell surface protein; CX1:1
Improved process robustness, product quality and biological efficacy of an anti-CD52 monoclonal antibody upon pH shift in Chinese hamster ovary cell perfusion culture
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; pH; Glycosylation; Charge heterogeneity; Complement-dependent cytotoxicity; Antibody-dependent cell-mediated cytotoxicity; Perfusion;
Aptamers as potential therapeutic agents for ovarian cancer
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Aptamers; Antibodies; EpCAM; Therapeutic; Targeted therapies; Ovarian cancer; ADCC; antibody-dependent cell-mediated cytotoxicity; ABC; ATP-binding cassette; BBB; blood brain barrier; CDC; complement-mediated cytolysis; CA125; Cancer Antigen 125; CSCs; ca
Implications of uterine NK cells and regulatory T cells in the endometrium of infertile women
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; ART; assisted reproductive technology; dNK cells; decidual natural killer cells; CTLA-4; cytotoxic T-lymphocyte antigen-4; EVT; extra-villous trophoblast; G-CSF; granulocyte colony-stimulating factor; G
Plasma N-glycome composition associates with chronic low back pain
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Glycan biomarker; Low back pain; Plasma N-glycosylation; Retrospective study; % Area; percentage of total integrated area of the chromatogram; 2-AB; 2-aminobenzamide; 2-PB; 2-picoline borane; AbSur; cohort of patients with acute inflammation that had abdo
Redox control of cancer cell destruction
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r
Bispecific antibodies for cancer therapy: A review
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; AE; adverse events; ALL; acute lymphoblastic leukemia; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; B-ALL; B-cell acute lymphoblastic leukemia; BiTES; Bi-sp
Cytokines for the induction of antitumor effectors: The paradigm of Cytokine-Induced Killer (CIK) cells
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ACT; Adoptive cell transfer; ADCC; Antibody-Dependent Cell-mediated Cytotoxicity; CAR; Chimeric antigen receptor; CIK; Cytokine Induced Killer cells; CMV; Cytomegalovirus; EGFR; Human epidermal growth factor 1; GVHD; Graft-versus-Host disease; ICI; Immune
B cell depleting therapy regulates splenic and circulating T follicular helper cells in immune thrombocytopenia
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Immune thrombocytopenia; T follicular helper cells; Rituximab; ADCC; antibody-dependent cell-mediated cytotoxicity; AID; autoimmune diseases; FC; fold change; GC; germinal center; ITP; immune thrombocytopenia; PBMC; peripheral blood mononuclear cells; PBL
Predictors of durable immune responses six months after the last vaccination in preventive HIV vaccine trials
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; AUC; area under the receiver operating characteristics curve; BAMA; binding antibody multiplex assay; CI; confidence interval; CV; cross-validation; ELISA; enzyme-linked immunosorbent assay; ELISpot; en
Research paperThaw-and-use target cells pre-labeled with calcein AM for antibody-dependent cell-mediated cytotoxicity assays
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; mAb; monoclonal antibody; NK; natural killer, PBMC, peripheral blood mononuclear cell; EC50; half maximal effective concentration; ET ratio; effector cell:target cell ratio; Fc; fragment crystallizable;
The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADC; antibody-drug conjugate; NHL; non-Hodgkin lymphoma; DLBCL; diffuse large B-cell lymphoma; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; MMAE; monomethyl auristatin E; SMCC; N-succinimidyl-4-(N-maleimidoe
Research paperCharacterization of FcγRIIIA effector cells used in in vitro ADCC bioassay: Comparison of primary NK cells with engineered NK-92 and Jurkat T cells
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; mAbs; monoclonal antibodies; Fab; fragment antigen-binding; Fc; fragment crystallizable; NK cells; natural killer cells; ADCC; antibody-dependent cell-mediated cytotoxicity; MOA; mechanisms of action; NFAT; nuclear factor of activated T cells; T cells; th
HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; HIV; human immunodeficiency virus; Env; HIV envelope protein; cART; combined antiretroviral therapy; EC; elite controller; IgG; immunoglobulin G; (n)Ab; (neutralizing) antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; CTL; cytotoxic T cell; T
Chimeric antigen receptor-engineered natural killer and natural killer T cells for cancer immunotherapy
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; aAPC; artificial antigen-presenting cells; αGalCer; α-galactosylceramide; ACT; adoptive cell transfer; ADCC; antibody-dependent cell-mediated cytotoxicity; ALL; Acute Lymphoblastic Leukemia; AML; acute lymphoid leukemia; CAR; chimeric antigen receptor;
Near infrared photoimmunotherapy of B-cell lymphoma
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Near infrared photoimmunotherapy; CD20; B-cell lymphoma; Monoclonal antibodies; Near infrared light; Molecular imaging; ADCC; antibody-dependent cell-mediated cytotoxicity; APC; antibody-photo absorber conjugate; CD; cluster of differentiation; CDC; compl
Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; Antibody-dependent cell-mediated cytotoxicity; ARV; Anti-retroviral; AZT; Zidovudine; bnAb; Broadly neutralizing antibody; CD4bs; CD4 binding site; dIgA; Dimeric IgA; FcRn; Neonatal Fc receptor; GalCer; Galactosyl ceramide; GI; Gastrointestinal; GU;
Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Fc; fragment crystallizable; IgG; immunoglobulin G; Fab; fragment antigen binding; FcγR; Fc gamma receptor; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; CDC; complement-dependent cytotoxicity;
Report on the second WHO integrated meeting on development and clinical trials of influenza vaccines that induce broadly protective and long-lasting immune responses: Geneva, Switzerland, 5-7 May 2014
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; CMI; cell-mediated immunity; COBRA; computationally optimized broadly reactive antigen; CoP; immune correlate of protection; HA; influenza haemagglutinin protein; HI; haemagglutination inhibition; IFN;
Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; AP; alkaline phosphatase; CDC; complement-mediated cytotoxicity; CH2; constant domain 2; DNP; 2,4-dinitrophenyl; EDTA; ethylenediaminetetraacetic aci
ReviewPreclinical and clinical development of inotuzumab-ozogamicin in hematological malignancies
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Ab; antibody; ADC; antibody-drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; AE; adverse event; ALL; acute lymphoblastic leukemia; AUC; the area under the plasma concentration time curve; AUCtau; area under the curve extrapolated ove
ReviewMast cells as targets for immunotherapy of solid tumors
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; FcÉRI; high affinity IgE Fc receptor; FcγRI; high affinity IgG Fc receptor; FcγRII; low affinity IgG Fc receptor; FGF; fibroblast growth factor; H1-H4; histamine receptors 1-4; HIF-1α; hypoxia i
Next-generation optimized biotherapeutics - A review and preclinical study
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADAs; anti-drug antibodies; ADC; antibody drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; ATL; adult T-cell leukemia-lymphoma; CCR4; CC chemokine receptor 4; CDC; complement-dependent cytotoxicity; CDR; complementary determining regio
Crystal structure of a novel asymmetrically engineered Fc variant with improved affinity for FcγRs
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; A/I ratio; activating FcγR binding to inhibitory FcγR binding; asym-mAb23; a novel asymmetrically engineered Fc; FcγR; Fcγ receptor; mAb; monoclo
Evaluation of a fully human monoclonal antibody against multiple influenza A viral strains in mice and a pandemic H1N1 strain in nonhuman primates
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; M2; matrix protein 2; M2e; ectodomain of M2; mAb; monoclonal antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; HA; hemagglutinin; NA; neuraminidase; Influenza A; Matrix protein 2; Antibody; Virus infect
Comparative functional characterization of canine IgG subclasses
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; cell-mediated cytotoxicity; CDR; complementarity determining region; Canine; Immunoglobulin; IgG subclass; Fc receptor; Effector functions;
A systematic review of dual targeting in HER2-positive breast cancer
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; ASCO; American Society of Clinical Oncology; CBR; clinical benefit rate; CHF; congestive heart failure; CI; confidence interval; DFS; disease free survival; EGFR; epidermal growth factor receptor; ER; e
Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; PBMC; peripheral blood mononuclear cell; NK cells; natural killer cells; LDH; lactate dehydrogenase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; EC50; measur
The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; Epidermal growth factor-like module containing mucin-like hormone receptor 1; eosinophil; hypereosinophilic syndrome; mAb therapy; afucosylated antibody; eosinophilia; ADCC; Antibody-dependent cell-mediated cytotoxicity; AEC; Absolute eosinophil count;
Comparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaques
Keywords: آنتی بادی-وابسته به سلول، سمیت سلولی; PBMCs; peripheral blood mononuclear cells; TNF-α; tumor necrosis factor α; IFN-γ; interferon γ; IM; intramuscular; IN; intranasal; O; oral; IT; intratracheal; IR; intrarectal; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCVI; antibody-depend