Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; AR, androgen receptor; cAMP, cyclic adenosine monophosphate; p57, Kip2, cyclin-dependent kinase inhibitor 1C; COX-2, cyclooxygenase-2; DC, deisobutyrylciclesonide; Dex, dexamethasone; KA, dissociation constant; ER, oestrogen rec
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Keywords: AP-1، پروتئین فعال کننده 1; Depression; Neurotoxicity; Pain; Seizure; Stroke; Traumatic brain injuryAD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AP-1, activator protein 1; ASD, autism spectrum disorder;
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; DAMP, damage associated molecular patterns; IRAK1, interleukin-1 receptor associated kinase-1; LBP, LPS binding protein; LPS, lipopolysacharide; MAPK, mitogen-activated protein kinase; MD2, myeloid differentiation factor 2; MHC,
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; AR, androgen receptor; DAPI, 4′,6-diamidino-2-phenylindole; Dex, dexamethasone; ER, estrogen receptor; GC, glucocorticoid; GR, glucocorticoid receptor; IκBα, nuclear factor of kappa light polypeptide gene enhancer in B cells inh
Keywords: AP-1، پروتئین فعال کننده 1; 2-AG, 2-arachidonoyl-glycerol; 5′UTR, untranslated region; AP-1, activator protein 1; AA, arachidonic acid; AEA, arachidonoyl-ethanolamide; ARE, AU-rich element; C/EBP, CCAAT-enhancer-binding protein; CRC, colorectal cancer; CREs, cAMP-response elements;
Keywords: AP-1، پروتئین فعال کننده 1; AIDS, Acquired immune deficiency syndrome; AIM2, Absent in melanoma 2; AMPs, Antimicrobial peptides; APCs, Antigen presenting cells; AP-1, Activator protein 1; APOBEC3, Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3; ASC, Apoptosis-as
Keywords: AP-1، پروتئین فعال کننده 1; Progesterone receptor (PR); Phosphorylation; SUMOylation; Gene expression; Estrogen receptor (ER); AntiprogestinsAF, activation function; AP-1, activator protein 1; CD, common docking; CDK2, cyclin dependent kinase 2; CK2, casein kinase II; DUSP6/MKP3, du
BACH1, the master regulator gene: A novel candidate target for cancer therapy
Keywords: AP-1، پروتئین فعال کننده 1; BACH1, BTB and CNC homology 1, basic leucine zipper transcription factor 1; CNC, cap ‘n’ collar; bZIP, basic leucine zipper; HO-1, hemoxygenas-1; MMP1, matrix metalloproteinase-1; CXCR4, C–X–C chemokine receptor type 4; AP-1, activator protein 1; MAF, tra
Steroidogenesis and early response gene expression in MA-10 Leydig tumor cells following heterologous receptor down-regulation and cellular desensitization
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; BSA, bovine serum albumin; CREB, cAMP response element binding protein; db-cAMP, dibutryl cAMP; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; ERG, early response gene; ERK1/2, extracellular signal regulat
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; DCFH-DA, 2′,7′-dichlorofluorescin diacetate; E-selectin, endothelial-leukocyte adhesion molecule-1; EGCG, epigallocatechin gallate; FBS, fetal bovine serum; GCL, glutamate-cysteine ligase; GCLC, glutamate-cysteine ligase catalyt
Erk-Creb pathway suppresses glutathione-S-transferase pi expression under basal and oxidative stress conditions in zebrafish embryos
Keywords: AP-1، پروتئین فعال کننده 1; Ahr, aryl hydrocarbon receptor; Akt, protein kinase B; AOE, antioxidant enzyme; AP-1, activator protein 1; cAMP, cyclic adenosine monophosphate; cat, catalase; CRE, cAMP response element; Creb, cAMP response element-binding protein; cyp1a, cytochrome P450
Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway
Keywords: AP-1، پروتئین فعال کننده 1; Diabetic nephropathy; Advanced glycation-end products; Polydatin; Sphingosine kinase 1; Fibronectin; Intercellular adhesion molecule-1AGEs, advanced glycation-end products; AP-1, activator protein 1; BUN, blood urea nitrogen; C17–S1P, C17-D-erythro-sphing
Temozolomide resistance in glioblastoma multiforme
Keywords: AP-1، پروتئین فعال کننده 1; Adaptive; Glioblastoma; Intrinsic; Resistance; Temodar; TemozolomideAGT (also known as MGMT), O6-methylguanine-DNA alkyltransferase; APE1, apurinic/apyrimidine endonuclease/redox factor-1; APNG, Alkylpurine-DNA-N-glycosylase; AP-1, activator protein 1; BB
Characterization of bovine A20 gene: Expression mediated by NF-κB pathway in MDBK cells infected with bovine viral diarrhea virus-1
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; AREs, adenylate- and uridylate-rich (AU-rich) elements; bp, base pair; Bcl10, B-cell lymphoma 10-encoded protein; Bcl3, B-cell lymphoma 3-encoded protein; BVDV-1, bovine viral diarrhea virus; CBP, CREB-binding protein; DUBs, deu
A molecular perspective on rituximab: A monoclonal antibody for B cell non Hodgkin lymphoma and other affections
Keywords: AP-1، پروتئین فعال کننده 1; ADCC, antibody dependent cellular cytotoxicity; AIDS, acquired immune deficiency syndrome; AIHA, autoimmune hemolytic anemia; Akt, also known as protein kinase B (PKB); AP-1, activator protein 1; Bak, BCL2-antagonist/killer 1; BAT box, a sequence of eleme
Genetic and functional analysis of the TBX3 gene promoter in indirect inguinal hernia
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; DSV, DNA sequence variant; IIH, indirect inguinal hernia; JDP2, Jun dimerization protein 2; SNPs, single-nucleotide polymorphisms; SRY, sex-determining region Y; TBX3, T-box transcription factor 3Indirect inguinal hernia; Geneti
Thioredoxin-like protein 2b facilitates colon cancer cell proliferation and inhibits apoptosis via NF-κB pathway
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; ASK1, apoptosis signal-regulating kinase 1; CT antigen, cancer-testis antigen; NF-κB, nuclear factor-κB; Txl-2, thioredoxin-like protein 2; Trx, thioredoxin; VCR, vincristineColon cancer; Proliferation; Apoptosis; Thioredoxin-li
Dual regulation of skin sensitizer-induced HMOX1 expression by Bach1 and Nrf2: Comparison to regulation of the AKR1C2-ARE element in the KeratinoSens cell line
Keywords: AP-1، پروتئین فعال کننده 1; AKR1C2, aldoketoreductase 1C2; AP-1, activator protein 1; ARE, antioxidant response element; Bach1, BTB and CNC homolog 1; DMEM, Dulbecco's Modified Eagle Medium; DMSO, dimethylsulfoxide; DNCB, 2,4-dinitrochlorobenzene; EC1.5/EC2/EC3, concentration for 1.
Bone marrow-derived c-jun N-terminal kinase-1 (JNK1) mediates liver regeneration
Keywords: AP-1، پروتئین فعال کننده 1; ANOVA, analysis of variance; ALT, alanine aminotransferase; AP-1, activator protein 1; APR, acute phase response; AST, aspartate aminotransferase; BM, bone marrow; BMT, bone marrow transplantation; BrdU, 5-bromo-2′-deoxyuridine; KC, Kupffer cells; FXR, fa
Type I IFN family members: Similarity, differences and interaction
Keywords: AP-1، پروتئین فعال کننده 1; ADAR1, adenosine deaminase acting on RNA 1; AP-1, activator protein 1; APCs, antigen presenting cells; ATF6, activating transcription factor 6; BCG, bacille Calmette–Guérin; cGAS, cyclic GMP-AMP synthase; CHIKV, Chickungunya virus; CRF2, class II cytokine
Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance
Keywords: AP-1، پروتئین فعال کننده 1; ABCB1, P-glycoprotein; ABCC1, multidrug resistance-associated protein; AP-1, activator protein 1; CSA, cyclosporine A; DFO, desferrioxamine; DNMT1, DNA methyltransferase 1; ERK, extracellular signal-regulated kinase; GST, glutathione S-transferase; IRP1,
Anti-inflammatory effects of 4′-demethylnobiletin, a major metabolite of nobiletin
Keywords: AP-1، پروتئین فعال کننده 1; 4DN, 4′-demethylnobiletin; LPS, lipopolysaccharide; iNOS, inducible nitric oxide synthase; COX-2, cyclooxygenase-2; NF-κB, nuclear factor-κB; AP-1, activator protein 1; Nrf2, nuclear factor erythroid 2-related factor 2; HO-1, heme oxygenase-1; NQO1, NADH
Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise
Keywords: AP-1، پروتئین فعال کننده 1; AMPK, AMP-dependent kinase; AP-1, Activator protein 1; aP2, Adipocyte protein 2; BAIBA, β-Aminoisobutyric acid; BAT, Brown adipose tissue; BDNF, Brain-derived neurotrophic factor; CaMK, Calcium/calmodulin-dependent protein kinase; C/EBPα, CCAAT-enhancer-b
Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators
Keywords: AP-1، پروتئین فعال کننده 1; 4-HNE, 4-hydroxynonenal; AP-1, activator protein 1; DMPO, 5,5-dimethyl-2-(8-octanoic acid)-1-pyrroline N-oxide; DNPH, 2,4-dinitrophenylhydrazine; ERK, extracellular signal-regulated kinase; JNK, Jun-N terminal kinase; MAPK, mitogen-activated protein kinas
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; PCB-NDL, polychlorinated biphenyl non-dioxin-like; RSV, resveratrol (3,5,4′-trihydroxy-trans-stilbene); EX-527, 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; SIRT1, sirtuin 1; MS, oligodeoxynucleotide missense; AS, oli
Genome-wide identification of hypoxia-inducible factor-1 and -2 binding sites in hypoxic human macrophages alternatively activated by IL-10
Keywords: AP-1، پروتئین فعال کننده 1; ADM, adrenomedullin; AP-1, activator protein 1; CBP, CREB binding protein; C/EBP, CCAAT/enhancer binding protein; ChIP-seq, chromatin immunoprecipitation-sequencing; EGR, early growth response; HUVEC, human umbilical vein endothelial cells; HIF, hypoxia-i
Modulation of aryl hydrocarbon receptor-regulated enzymes by trimethylarsine oxide in C57BL/6 mice: In vivo and in vitro studies
Keywords: AP-1، پروتئین فعال کننده 1; 4-OHE2, 4-hydroxy estradiol; AhR, aryl hydrocarbon receptor; Aldh3, cytosolic “class 3” aldehyde dehydrogenase; AP-1, activator protein 1; ARE, antioxidant response element; ARNT, aryl hydrocarbon receptor nuclear translocator; AS3MT, arsenic methyltransf
Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair
Keywords: AP-1، پروتئین فعال کننده 1; Oxidative stress; Redox signaling; Gene regulation; Epigenetics; DNA repair5-hmC, 5-hydroxymethylcytosine; 5-mC, 5-methylcytosine; AP-1, activator protein 1; Ape-1, apurinic/apyrimidinic endonuclease 1; AREs, AU-rich elements; BER, base excision repair; C
A novel homozygous Fas ligand mutation leads to early protein truncation, abrogation of death receptor and reverse signaling and a severe form of the autoimmune lymphoproliferative syndrome
Keywords: AP-1، پروتئین فعال کننده 1; AKT, v-akt murine thymoma viral oncogene homolog 1; ALPS, autoimmune lymphoproliferative syndrome; AP-1, activator protein 1; CASP10, caspase-10; CCND1, cyclin D1; DN T cells, double negative T cells; ERK1/2, extracellular-signal regulated kinase 1/2; Fas
Interplay between estrogen and retinoid signaling in breast cancer – Current and future perspectives
Keywords: AP-1، پروتئین فعال کننده 1; AF-1, activator function 1; AF-2, activator function 2; APL, acute promyelocytic leukemia; AP-1, activator protein 1; Co-A, coactivator; Co-R, corepressor; CREB, cyclic adenosine monophosphate-responsive element-binding protein; CYP, cytochrome P450; ER,
Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller
Keywords: AP-1، پروتئین فعال کننده 1; 1D NMR, one-dimensional nuclear magnetic resonance spectroscopy; 2D NMR, two-dimensional nuclear magnetic resonance spectroscopy; ANOVA, analysis of variance; AP-1, activator protein 1; CC, column chromatography; CDCl3, deuterated chloroform; C/EBP, CCAAT
Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region
Keywords: AP-1، پروتئین فعال کننده 1; 5′-UTR, 5′-untranslated region; ALP, alkaline phosphatase; AP-1, activator protein 1; ATF, activating transcription factor; bglap2, bone gamma-carboxyglutamate protein 2; BMSC, bone marrow stromal cells; cDNA, complementary deoxyribonucleic acid; CdxA, ca
Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization
Keywords: AP-1، پروتئین فعال کننده 1; AhR, aryl hydrocarbon receptor; AMD, age related macular degeneration; AP-1, activator protein 1; APE1, apurinic endonuclease 1/redox factor-1; ApoE, apolipoprotein E; CBF/NF-Y/YY1, CCAAT binding factor/nuclear factor-Y/Yin Yang 1; CECs, choroidal endothe
Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures
Keywords: AP-1، پروتئین فعال کننده 1; Oxidative stress; Epigenetics; Base excision repair; Developmental origin5mC, 5-methylcytosine; 8-oxodG, 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1, activator protein 1; APE1, apurinic/apyrimidinic endonuclease 1; BER, base excision repair; CREB, cAMP resp
Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways
Keywords: AP-1، پروتئین فعال کننده 1; COX-2, cyclooxygenase-2; IL, interleukin; TNF-α, tumor necrosis factor-α; iNOS, inducible nitric oxide synthase; AP-1, activator protein 1; HIF-1α, hypoxia-inducible factor 1-alpha; VEGF, vascular endothelial growth factor; MMP-9, matrix metalloproteinase
The receptor for advanced glycation end-products: A complex signaling scenario for a promiscuous receptor
Keywords: AP-1، پروتئین فعال کننده 1; Akt, a member of serine–threonine kinase family; AP-1, activator protein 1; Cdc 42, cell division cycle 42; Erk1/2, extracellular signal-regulated kinases 1/2; IRAKs, IL-1R associated kinases; JAK, Janus kinase; JNK, Jun N-terminal kinase; m-Dia 1, mammal
Elk1 and AP-1 sites in the TBP promoter mediate alcohol-induced deregulation of Pol III-dependent genes
Keywords: AP-1، پروتئین فعال کننده 1; JNKs, c-Jun N-terminal kinases; AP-1, activator protein 1; Elk-1, ETS domain-containing protein; HCC, hepatocellular carcinoma; Pol III, polymerase III; ADH, alcohol dehydrogenases; Luc, luciferase; NS5A, non-structure protein 5AAlcohol; TBP; Elk1; AP-1;
Negative regulation of inflammation by SIRT1
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; CK2, casein kinase II; COPD, chronic obstructive pulmonary disease; COX-2, cyclooxygenase-2; CSE, cigarette smoke extract; DYRK1A, dual specificity tyrosine phosphorylation-regulated kinase 1A; FoxO, forkhead box O transcription
Impact of LIF (leukemia inhibitory factor) expression in malignant melanoma
Keywords: AP-1، پروتئین فعال کننده 1; Angptl4, Angiopoietin-Like 4; AP-1, Activator Protein 1; DFX, Desferrioxamine; DP, 2,2 Dipyridyl; GAPDH, Glyceraldehydes-3-phosphate dehydrogenase; HIF-1, Hypoxia inducible factor; NF-κB, Nuclear factor kappa B; LIF, Leukemia inhibitory factor; PI3K, Phos
12-Deoxyphorbol 13-palmitate inhibit VEGF-induced angiogenesis via suppression of VEGFR-2-signaling pathway
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, Activator Protein 1; bFGF, Basic fibroblast growth factor; CAM, Chorioallantoic membrane; ECM, Endothelial cell medium; ERK, Extracellular signal-regulated kinase; HUVEC, Human umbilical vein endothelial cells; JNK, c-Jun N-terminal kinase; MAPK, Mi
Transcriptional activity of c-Jun is critical for the suppression of AR function
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; CRPC, castration-resistant prostate cancer; DBD, DNA-binding domain; ARE, androgen-response element; DHT, dihydrotestosterone; bZIP, basic region leucine zipper; TRE, TPA-responsive elements; CRE, cyclic AMP-responsive elements;
The GluK4 kainate receptor subunit regulates memory, mood, and excitotoxic neurodegeneration
Keywords: AP-1، پروتئین فعال کننده 1; ABR, auditory brainstem response; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA, analysis of variance; AP-1, activator protein 1; ATF-2, activating transcription factor 2; CA1, cornu ammonis 1; CA2, cornu ammonis 2; CA3, cornu ammonis
MAP kinase signalling cascades and transcriptional regulation
Keywords: AP-1، پروتئین فعال کننده 1; AML, acute myeloid leukemia; AP-1, activator protein 1; ASH2L, absent, small, or homeotic-like; ATAC, Ada2A containing; ATF1/2, activating transcription factor 1/2; BAF60c/155, BRG1-associated factor 60c/155; Bcd, bicoid; bHLH, basic helix loop helix; BMK
CD46: The ‘multitasker’ of complement proteins
Keywords: AP-1، پروتئین فعال کننده 1; ADAM, a disintegrin and metalloproteinase; AP-1, activator protein 1; aHUS, atypical hemolytic uremic syndrome; AMD, age-related macular degeneration; Bcl-2, B-cell lymphoma 2; CCL, chemokine (C-C motif) ligand; CCP, complement control protein domain; CSL
Immediate early response genes and cell transformation
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, Activator protein 1; CREB, Cyclic AMP response element-binding protein; Dnmt, DNA cytosine-5′-methyltransferase; EGF, Epidermal growth factor; ERK1/2, Extracellular signal-related kinase 1 and 2; HDAC, Histone deacetylase; MAPK, Mitogen-activated pr
Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: Possible therapeutic targets?
Keywords: AP-1، پروتئین فعال کننده 1; Free radicals; NO synthases; NO inhibitors; ADMA; BH4; Cardiovascular diseaseADMA, asymmetric dimethylarginine; AF, atrial fibrillation; AGXT2, alanine-glyoxylate aminotransferase 2; AP-1, activator protein 1; ApoE-KO, apolipoprotein E knockout; ARE, anti
Glutathione synthesis and its role in redox signaling
Keywords: AP-1، پروتئین فعال کننده 1; ANT, adenine nucleotide translocator; AP-1, activator protein 1; ATF4, activating transcription factor 4; CBP, CREB binding protein; EpRE, electrophile response element; ERK, extracellular signal regulated protein kinase; GSK-3β, glycogen synthase kinase
Anti-superoxide and anti-peroxynitrite strategies in pain suppression
Keywords: AP-1، پروتئین فعال کننده 1; TEMPOL, 4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl; AP-1, activator protein 1; CaMKII, calcium/calmodulin-dependent protein kinase II; JNK, c-Jun N-terminal kinase; CNS, central nervous system; CIPN, chemotherapy-induced peripheral neuropathy; COX, cy
Rare sugar d-allose strongly induces thioredoxin-interacting protein and inhibits osteoclast differentiation in Raw264 cells
Keywords: AP-1، پروتئین فعال کننده 1; AP-1, activator protein 1; DMEM, Dulbecco modified Eagle medium; FBS, fetal bovine serum; MEM, minimum essential medium; NFAT, nuclear factor of activated T cells; NF-κB, nuclear factor-κB; PBS, phosphate-buffered saline; RANKL, receptor activator of nucl
ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway
Keywords: AP-1، پروتئین فعال کننده 1; Abro1, Abraxas brother 1; DUB, deubiquitinating enzyme; BRISC, BRCC36 isopeptidase complex; BRCA1, breast cancer 1; AP-1, activator protein 1; ATF, activating transcription factor; BRCC36, BRCA1/BRCA2-containing complex, subunit 3; BRE, brain and reproduc