Keywords: آپامین; Linaria vulgaris; Hippocampal culture; Calcium imaging; Alcohol; 1-EBIO; Apamin; Acetylpectolinarin; Flavonoid; Extract;
مقالات ISI آپامین (ترجمه نشده)
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Keywords: آپامین; Apamin; Atrial fibrillation; Melanocyte-like cells; Optical mapping; SK channels;
Keywords: آپامین; Bee venom; Apamin; Melittin; Phospholipase A2; Antioxidant/anti-inflammatory; Cytotoxic;
Keywords: آپامین; GC; glucocorticoid; GR; glucocorticoid receptor; DEX; dexamethasone; SKCa; small calcium-dependent potassium channel; BKCa; big calcium-dependent potassium channel; APA; apamin; ChTX; charybdotoxin; PE; phenylephrine; INDO; indomethacin; L-NAME; L-NG-nitr
Neonatal exposure to sevoflurane caused cognitive deficits by dysregulating SK2 channels and GluA2-lacking AMPA receptors in juvenile rat hippocampus
Keywords: آپامین; Anesthetics exposure; Apamin; GluA2-lacking AMPA receptors; Hippocampus; Cognitive function;
Calcium-activated SK potassium channels are key modulators of the pacemaker frequency in locus coeruleus neurons
Keywords: آپامین; Locus coeruleus; Pacemaking; SK channels; Apamin; NS309; Cav channels;
Apamin inhibits TNF-α- and IFN-γ-induced inflammatory cytokines and chemokines via suppressions of NF-κB signaling pathway and STAT in human keratinocytes
Keywords: آپامین; Apamin; Atopic dermatitis; Type 2 helper T lymphocyte chemokine; NF-κB; STAT;
Regulation of excitability in tonic firing substantia gelatinosa neurons of the spinal cord by small-conductance Ca2+-activated K+ channels
Keywords: آپامین; Ca2+-activated K+ channels; Apamin; 1-EBIO; Spinal cord; Pain; 1-EBIO; 1-ethyl-2-benzimidazolinone; aCSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AP-5; D-2-amino-5-phosphon
Apamin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through suppressions of activated Akt and Erk signaling pathway
Keywords: آپامین; Apamin; VSMC; Proliferation; Migration; Cell cycle
Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration
Keywords: آپامین; Docking; Rational design; Butanamide; Benzyloxy; Enantiomers; Small conductance calcium-activated K+ channels; Apamin; In vitro binding; Isoquinoline;
Apamin inhibits hepatic fibrosis through suppression of transforming growth factor β1-induced hepatocyte epithelial-mesenchymal transition
Keywords: آپامین; Apamin; EMT; Liver fibrosis; Hepatocyte; TGF-β1; CCl4;
Ginsenoside Re enhances small-conductance Ca2Â +-activated K+ current in human coronary artery endothelial cells
Keywords: آپامین; Apamin; Ginseng; Ion channel; Whole-cell patch clamp technique;
Increased Small Conductance Calcium-Activated Potassium Type 2 Channel-Mediated Negative Feedback on N-methyl-D-aspartate Receptors Impairs Synaptic Plasticity Following Context-Dependent Sensitization to Morphine
Keywords: آپامین; Apamin; hippocampus; locomotor activity; long-term potentiation; PP2A; SK2-NMDA loop;
Functional consequences of retro-inverso isomerization of a miniature protein inhibitor of the p53-MDM2 interaction
Keywords: آپامین; Retro-inverso peptide; p53; MDM2; MDMX; d-Peptide; Apamin; Stingin;
Apamin inhibits THP-1-derived macrophage apoptosis via mitochondria-related apoptotic pathway
Keywords: آپامین; Atherosclerosis; Apoptosis; Apamin; oxLDL
Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties
Keywords: آپامین; ACSF; artificial cerebral spinal fluid; AHP; afterhyperpolarization; AP; action potential; AP5; D-2-amino-5-phosphonovalerate; 4-AP; 4-aminopyridine; AVPNs; airway vagal preganglionic neurons; CbTx; charybdotoxin; cNA; compact portion of the nucleus ambig
Blocking SK channels impairs long-term memory formation in young chicks
Keywords: آپامین; Small-conductance calcium-activated potassium channel; SK channel; Apamin; Discriminative avoidance learning; Memory; Chick;
Functional reduction of SK3-mediated currents precedes AMPA-receptor-mediated excitotoxicity in dopaminergic neurons
Keywords: آپامین; Dopaminergic; SK channels; Apamin; 1-Ebio; CyPPA; NS8593 AMPA; Excitotoxicity; NeuroprotectionSK, small-conductance calcium-activated potassium channels; ISK, SK channel-mediated current; IAHP, afterhyperpolarization; VDCC, voltage-dependent calcium chann
Apamin, a selective blocker of SKCa channels, inhibits posthypoxic hyperexcitability but does not affect rapid hypoxic preconditioning in hippocampal CA1 pyramidal neurons in vitro
Keywords: آپامین; Hippocampal slices; Hypoxia; Apamin; Population spike; SK-type potassium channels; Posthypoxic hyperexcitability; Rapid hypoxic preconditioning
Apamin reduces neuromuscular transmission by activating inhibitory muscarinic M2 receptors on motor nerve terminals
Keywords: آپامین; Apamin; Fade; Choline; Muscarinic receptors; Skeletal muscle
Ictal activity induced by group I metabotropic glutamate receptor activation and loss of afterhyperpolarizations
Keywords: آپامین; CA3; Hippocampus; Epilepsy; Apamin; 1-EBIO; DCEBIO
Quantification of melittin and apamin in bee venom lyophilized powder from Apis mellifera by liquid chromatography–diode array detector–tandem mass spectrometry
Keywords: آپامین; Melittin; Apamin; Crude bee venom lyophilized powder; LC–DAD–MS/MS
Complex actions of neurotensin in ascending and sigmoid colonic muscle: Involvement of enteric mediators
Keywords: آپامین; Neurotensin; Human colon; Neuronal; Indomethacin; Apamin; Nifedipine;
Distribution, expression and functional effects of small conductance Ca-activated potassium (SK) channels in rat myometrium
Keywords: آپامین; Uterus; Ca signalling; Outward current; Apamin; Smooth muscle; BK;
Mechanisms of changes in coronary arterial tone induced by bee venom toxins
Keywords: آپامین; Melittin; Apamin; Relaxation; Contraction; Porcine coronary artery; Calcium-activated potassium channels
In vivo pharmacological manipulation of small conductance Ca2+-activated K+ channels influences motor behavior, object memory and fear conditioning
Keywords: آپامین; Memory encoding; Object recognition; Apamin; Mice; Fear conditioning; SK channel; EBIO; CyPPA;
SK channel blocker apamin attenuates the effect of SSRI fluoxetine upon cell firing in dorsal raphe nucleus: A concomitant electrophysiological and electrochemical in vivo study reveals implications for modulating extracellular 5-HT
Keywords: آپامین; In vivo dual probing; Electrophysiology and voltammetry; Serotonin; Rat brain; Hippocampus; Frontal cortex; Amygdala; Dorsal raphe nucleus; Apamin; Fluoxetine
Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
Keywords: آپامین; SK2; Action potential; Apamin; Repolarization reserve; Intracellular calcium;
Contribution of apamin-sensitive SK channels to the firing precision but not to the slow afterhyperpolarization and spike frequency adaptation in snail neurons
Keywords: آپامین; Apamin; Firing precision; Spike frequency adaptation; Slow AHP; Snail neuron;
Apamin increases 5-HT cell firing in raphe dorsalis and extracellular 5-HT levels in amygdala: A concomitant in vivo study in anesthetized rats
Keywords: آپامین; Apamin; In vivo voltammetry; Electrophysiology; Serotonin; Amygdala; Raphe dorsalis; Potassium channel; Anesthetized rats
Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels
Keywords: آپامین; 2-Aminothiazole; Small conductance potassium channel; Potassium channel blockers; Apamin
Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine KCa channel blockers
Keywords: آپامین; Non-apamin displacing; Small conductance potassium channel; Pyrrazolopyrimidine; Apamin;
Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca2+-activated K+ channel blockers
Keywords: آپامین; Apamin; Tetrahydroisoquinoline; Patch-clamp; Neurons; Motor activity; Stereoisomer;
The role of small-conductance Ca2+-activated K+ channels in the modulation of 4-aminopyridine-induced burst firing in rat cerebellar Purkinje cells
Keywords: آپامین; SK channels; Purkinje neurons; Apamin; 4-AP-induced burst; Ca2+ spikes; Na+ spikes
Differential inhibitory control of circular and longitudinal smooth muscle layers of Balb/C mouse small intestine
Keywords: آپامین; Longitudinal muscle; Circular muscle; Small intestine; Nitric oxide; Apamin
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SKCa)
Keywords: آپامین; Quinoline; Aminoquinoline; Guanidine; Apamin; Potassium ion channel; Calcium activated; SKCa; SK3; AHP; After-hyperpolarization
Blockade of Ca2+-activated K+ channels by galantamine can also contribute to the potentiation of catecholamine secretion from chromaffin cells
Keywords: آپامین; Galantamine; KCa2 channels; Catecholamines; Chromaffin cell; Apamin
Mechanisms for modulation of mouse gastrointestinal motility by proteinase-activated receptor (PAR)-1 and -2 in vitro
Keywords: آپامین; Proteinase (protease)-activated receptor (PAR); Stomach; Intestine; Gastrointestinal smooth muscle; Contraction; Relaxation; Apamin; Indomethacin; Capsaicin; PAR-2-knockout mouse
Paraoxon suppresses Ca2+ spike and afterhyperpolarization in snail neurons: Relevance to the hyperexcitability induction
Keywords: آپامین; Paraoxon; Ca2+ spike; Neuronal excitability; AHP; Apamin
The functional consequences of paraoxon exposure in central neurones of land snail, Caucasotachea atrolabiata, are partly mediated through modulation of Ca2+ and Ca2+-activated K+-channels
Keywords: آپامین; Afterhyperpolarization; Apamin; Caucasotachea atrolabiata; Calcium dependent potassium channels; Firing precision; Neuronal activity; Paraoxon; Post-train AHP
Apamin produces selective improvements of learning in rats
Keywords: آپامین; Apamin; Learning; Memory; Rat;
Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test
Keywords: آپامین; Meloxicam; Antinociception; K+ channels; Apamin; Charybdotoxin; 4-aminopyridine; Tetraethylammonium; Glibenclamide; Tolbutamide; Formalin test;
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib
Keywords: آپامین; Lumiracoxib; K+ channel; NO-cyclic GMP pathway; Charybdotoxin; Apamin; Margatoxin; Serotonergic system; Opioid receptor;