
LC–MS-based holistic metabolic profiling. Problems, limitations, advantages, and future perspectives
Keywords: APCI, atmospheric pressure chemical ionisation; CE, capillary electrophoresis; DoE, design of experiment; ESI, electrospray ionisation; FT-ICR-MS, Fourier transformation ion cyclotron resonance mass spectrometry; GC–MS, gas chromatography–mass spectrometr