Keywords: محدوده تحت منحنی زمان غلظت پلاسما; SOD; superoxide dismutase; SK; streptokinase; PEG; polyethylene glycol; CAR; peptide CARSKNK; BSA; Bovine serum albumin; PVA; polyvinylalcohol; HPMC; hydroxypropyl methylcellulose; PLGA; polylactic-co-glycolic acid; HP-β-CD; hydroxypropyl-β-cyclodextrin
مقالات ISI محدوده تحت منحنی زمان غلظت پلاسما (ترجمه نشده)
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Keywords: محدوده تحت منحنی زمان غلظت پلاسما; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under the plasma concentration-time curve; BMI; body mass index (BMI); Cmax; maximum plasma concentration; CRPus; ultrasensitive C-reactive protein; GGT; gamma-glutamyl transferas
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; DCX; docetaxel; PK; phamacokinetic; PD; pharmacodynamic; HPLC; high-performance liquid chromatography; UV; ultraviolet; MS/MS; tandem mass spectrometry; UPLC; ultra-performance liquid chromatography; MTBE; methyl t-butyl ether; LC; liquid chromatography;
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC; area under the plasma concentration-time curve; BDMC; bis-demethoxycurcumin; Cmax; maximum plasma concentration; DMC; demethoxycurcumin; NC; native curcuminoids; NCP; native curcuminoids and phytochemicals; MC; micellar curcuminoids; MCP; micellar
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AED; antiepileptic drug; ANOVA; analysis of variance; AUC; area under the plasma concentration-time curve; AUCinf; area under the plasma concentration-time curve from zero to infinity; AUC(0-t); area under the plasma concentration-time curve from
Food-drug interactions involving multiple mechanisms: A case study with effect of Capsaicin on the pharmacokinetics of Irinotecan and its main metabolites in rat
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; APC; 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxy-camptothecin; AUC; Area under the plasma concentration-time curve; CAP; Capsaicin; CES; Carboxylesterase; CPT; Camptothecin; CPT-11; Irinotecan; CYP; cytochrome P450; DMEs; Drug-meta
Effects of sulfur-fumigation on the pharmacokinetics, metabolites and analgesic activity of Radix Paeoniae Alba
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC; area under the plasma concentration-time curve; BS; Radix Paeoniae Alba; CID; collision-induced dissociation; CL; clearance; Cmax; maximum plasma concentration; FDA; US Food and Drug Administration; HPLC/UV; high performance liquid chromatography/u
Strategies to improve the prediction accuracy of hepatic intrinsic clearance of three antidiabetic drugs: Application of the extended clearance concept and consideration of the effect of albumin on CYP2C metabolism and OATP1B-mediated hepatic uptake
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC; area under the plasma concentration-time curve; BSA; bovine serum albumin; CCK-8; cholecystokinin octapeptide-8; CYP; cytochrome P450; E1S; estrone-3 sulfate; FAF; fatty-acid-free; HBSS; Hanks' balanced salt solution; HEK; human embryonic kidney; H
A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; Aconitum carmichaeli Debx.; Aconitum alkaloids; Pharmacokinetics; Herb-drug interactions; Toxicology; Personalized medicine; DMEs; drug-metabolizing enzymes; ETs; efflux transporters; BB; bioavailability barrier; DDAs; diester-diterpene alkaloids; MDAs; m
Intestinal Drug Interactions Mediated by OATPs: A Systematic Review of Preclinical and Clinical Findings
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; drug interaction; inhibition; transporter; organic anion-transporting polypeptide transporters; intestinal absorption; polymorphism; AUC; area under the plasma concentration-time curve; DDIs; drug-drug interactions; EMA; European Medicines Agency; FDA
Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; cytochrome P450; drug interaction; hepatic clearance; mathematical model; organic anion-transporting polypeptide transporters; pharmacokinetics; AUC; area under the plasma concentration-time curve; CL; clearance; CLint,all; overall hepatic intrinsic cle
Involvement of organic cation transporter 3 (Oct3/Slc22a3) in the bioavailability and pharmacokinetics of antidiabetic metformin in mice
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; Metformin; OCT3; Transporter; Intestinal absorption; Bioavailability; Mouse; AUC; area under the plasma concentration-time curve; CL; clearance; Cmax; maximum concentration; OCT/Oct; organic cation transporter; SLC; solute carrier; tmax; time to maximum
Liquid chromatography-tandem mass spectrometric assay for the tyrosine kinase inhibitor afatinib in mouse plasma using salting-out liquid-liquid extraction
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC; area under the plasma concentration-time curve; CHMP; Committee for Medicinal Products for Human Use; EGFR; epidermal growth factor receptor; FDA; Food and Drug Administration; FVB; Friend Leukemia Virus; HER; human epidermal growth-factor receptor
Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(â/â) rats
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; P-glycoprotein; Central nervous system; Brain; Cerebrospinal fluid; Interstitial fluid; Microdialysis; Rats; Drug discovery; AUC; area under the plasma concentration-time curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; BCSFB;
High-performance liquid chromatography-tandem mass spectrometry method for the determination of perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist in human plasma
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AED; anti-epileptic drugs; AMPA; α-amin-3-hydroxyl-5methyl-4isoxazolepropionic acid; AUC; area under the plasma concentration-time curve; AUC0-inf; AUC extrapolated to infinity; AUC0-last; AUC to the last time points; AUMC; area under the first mom
Liquid chromatography-tandem mass spectrometric assay for the cyclin-dependent kinase inhibitor AT7519 in mouse plasma
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC0ââ; area under the plasma concentration-time curve; CDK; cyclin-dependent kinase; Cmax; maximum plasma concentration; EDTA; ethylenediaminetetraacetic acid; i.p.; intraperitoneal; IS; internal standard; MYCN; V-myc myelocytomatosis viral related
Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; α-ZAL; α-zearalanol; α-ZEL; α-zearalenol; β-ZAL; β-zearalanol; β-ZEL; β-zearalenol; ACN; acetonitrile; AUC; area under the plasma concentration-time curve; BW; body weight; Cl; clearance; Cmax; maximum plasma concentration; DON; deoxynivalenol;
P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC; area under the plasma concentration-time curve; Cmax; maximum drug concentration in plasma; Tmax; the time after administration of a drug when the maximum plasma concentration is reached; BBB; blood-brain barrier; BCRP; breast cancer resistance p
Research ArticleA phase 1, randomized, placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; AUC; area under the plasma concentration-time curve; BMI; body mass index; EC50; 50% effective inhibitory concentration; EC90; 90% effective inhibitory concentration; HCV; hepatitis C virus; PEG-IFN; peginterferon alfa; RBV; ribavirin; NS5A protein; Vir
Phase I Study of Heat-Deployed Liposomal Doxorubicin during Radiofrequency Ablation for Hepatic Malignancies
Keywords: محدوده تحت منحنی زمان غلظت پلاسما; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under the plasma concentration-time curve; AUC0-â; area under the plasma concentration-time curve from time 0 to infinity; DLT; dose-limiting toxicity; LTLD; lyso-thermosens