Keywords: آرستین; Bradykinin; Myometrium; Arrestin; Migration; Myometrial contraction; B2 receptorB2R, bradykinin B2 receptor; [Ca2+]i, intracellular calcium concentration; ERK, extracellular signal-regulated kinase; GPCR, G protein-coupled receptor; GRK, G protein-coupled
مقالات ISI آرستین (ترجمه نشده)
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Keywords: آرستین; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; WT; wild type; Rh; dark unphosphorylated rhodopsin; Rh*; light-activated unphosphorylated rhodopsin; P-Rh; dark phosphorylated rhodopsin; P-Rh*; light-activated phosphorylated rhodo
Non-visual arrestins regulate the focal adhesion formation via small GTPases RhoA and Rac1 independently of GPCRs
Keywords: آرستین; Arrestin; Small GTPases; RhoA; Rac1; Cell spreading; Cell motility; Actin; Focal adhesions;
GPCR desensitization: Acute and prolonged phases
Keywords: آرستین; Endocytosis; Arrestin; Ubiquitin; Phosphorylation; Recycling;
Translating in vitro ligand bias into in vivo efficacy
Keywords: آرستین; BRET; bioluminescence resonance energy transfer; DPD; deoxypyridinoline; GPCR; G protein-coupled receptor; RAi; intrinsic relative activity; NHERF2; Na+/H+ exchanger regulatory factor 2; PKA; protein kinase A; PKC; protein kinase C; PTH; parathyroid hormo
Different mode of arrestin-3 binding at the human Y1 and Y2 receptor
Keywords: آرستین; ANOVA; analysis of variance; arr; arrestin; BRET; bioluminescence resonance energy transfer; EYFP; enhanced yellow fluorescent protein; FLR; finger loop region; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; YxR; neuropeptide Yx
Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics
Keywords: آرستین; 7TMR; GPCR; Arrestin; β-Arrestin; Biased agonism; Biased agonist; Mass spectrometry; Proteomics; Pharmacology; Drug discovery;
C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment
Keywords: آرستین; ANOVA; analysis of variance; arr; arrestin; BRET; bioluminescence resonance energy transfer; EYFP; enhanced yellow fluorescent protein; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; hPP; human pancreatic polypeptide; hY1R; huma
ReviewNew Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy
Keywords: آرستین; Antipsychotics; Arrestin; Dopamine; Functional selectivity; Schizophrenia; System bias;
Arrestin-2 and arrestin-3 differentially modulate locomotor responses and sensitization to amphetamine
Keywords: آرستین; Amphetamine; Locomotor sensitization; Arrestin; Receptor desensitization; Arrestin-mediated signaling;
Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors
Keywords: آرستین; Arrestin; GPCRs; Receptor specificity; Protein-protein interactions; Protein engineering;
Reciprocal regulation of β2-adrenoceptor-activated cAMP response-element binding protein signalling by arrestin2 and arrestin3
Keywords: آرستین; ATF-1; activation of transcription factor-1; β1AR; β1 adrenoceptor; β2AR; β2 adrenoceptor; CGP-20712A; 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride; CREB; cAMP respo
Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α2A adrenergic receptor ligands
Keywords: آرستین; Antipsychotic; Endocytosis; Arrestin; Biased agonism; α2 adrenergic receptor; Lipid raft;
Angiotensin type 1A receptor regulates β-arrestin binding of the β2-adrenergic receptor via heterodimerization
Keywords: آرستین; GPCR; Heterodimerization; Arrestin; BRET; Biased signaling; G protein-coupled receptors; GPCR; Angiotensin type 1A receptor; AT1R; β2-adrenergic receptors; β2AR; serotonin 2C receptor; 5HT2CR; angiotensin II; AngII; Isoproterenol; ISO; Renilla luciferas
Archival ReportAdaptive Activation of a Stress Response Pathway Improves Learning and Memory Through Gs and β-Arrestin-1-Regulated Lactate Metabolism
Keywords: آرستین; Adrenergic receptor; Arrestin; G protein; HIF-1α; Memory; Stress;
Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications
Keywords: آرستین; AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Î1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem
β-arrestins regulate gonadotropin receptor-mediated cell proliferation and apoptosis by controlling different FSHR or LHCGR intracellular signaling in the hGL5 cell line
Keywords: آرستین; hGL5; FSHR; LHCGR; Apoptosis; GPCR; Arrestin;
Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation
Keywords: آرستین; G protein-coupled receptor; Signaling bias; Arrestin; Informatic; Transcriptome; In vivo;
Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins
Keywords: آرستین; GPCR; G protein; Arrestin; GRK; Signal transduction; Biased signaling;
FFA4 receptor (GPR120): A hot target for the development of anti-diabetic therapies
Keywords: آرستین; GPR120; Glucose metabolism; Lipid; Arrestin; Biased signaling;
Emerging Functional Divergence of β-Arrestin Isoforms in GPCR Function
Keywords: آرستین; G protein-coupled receptors; arrestin; cellular signaling; biased agonism; desensitization; mitogen-activated protein kinase.
Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes
Keywords: آرستین; GPCR; G protein-coupled receptor; arr; arrestin; NPY; neuropeptide Y; Y1R; neuropeptide Y1 receptor; Y2R; neuropeptide Y2 receptor; BRET; bioluminescence resonance energy transfer; ANOVA; analysis of variance; arr-3-K2A; arrestin-3-Lys11 AlaLys12Ala; arr-
Probing biased/partial agonism at the G protein-coupled A2B adenosine receptor
Keywords: آرستین; GPCR; Adenosine receptor; Purines; Cyclic AMP; Calcium; Arrestin; BAY60-6583 (BAY, LUF6210); 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]acetamide; cyclic AMP (cAMP); 3â²5â²-cyclic adenosine monophosphate; CGS21680; 2-[p-(2
Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains
Keywords: آرستین; GPCR; G protein-coupled receptor; JNK; c-Jun NH2-terminal protein kinase; MAPK; mitogen-activated protein kinase; MKK or MAPKK; MAP kinase kinase; MAPKKK; MAP kinase kinase kinase; ASK1; Apoptosis signal-regulating kinase 1, a.k.a. mitogen-activated prote
Activation of Bombyx neuropeptide G protein-coupled receptor A4 via a Gαi-dependent signaling pathway by direct interaction with neuropeptide F from silkworm, Bombyx mori
Keywords: آرستین; Neuropeptide; GPCR; Signaling; Arrestin; MAP kinases; AKH; adipokinetic hormone; cAMP; cyclic AMP; CRE; cAMP-response element; EGFP; enhanced green fluorescent protein; ERK1/2; extracellular signal-regulated kinase1/2; Gi; inhibitory GTP-binding protein o
Quantitative morphological analysis of arrestin2 clustering upon G protein-coupled receptor stimulation by super-resolution microscopy
Keywords: آرستین; Super-resolution microscopy; Clustering; Arrestin; G-protein coupled receptor; Single-molecule fluorescence microscopy;
Inhibitory effects of cytoskeleton disrupting drugs and GDP-locked Rab mutants on bradykinin B2 receptor cycling
Keywords: آرستین; Arrestin; Bradykinin; Bradykinin B2 receptors; Microtubules; Actin; Rab proteins;
One-step purification of a functional, constitutively activated form of visual arrestin
Keywords: آرستین; Arrestin; Vision; Desensitization; Rhodopsin; Affinity fusion-tag; Subtilisin; Protein purification; Automated chromatography;
S-nitrosylation-regulated GPCR signaling
Keywords: آرستین; GPCR; GRK; Arrestin; Dynamin; S-nitrosylation;
Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin
Keywords: آرستین; α2 Adrenergic receptor; Arrestin; Depression; Desipramine; Forced swim test; Spinophilin5HT, serotonin; AR, adrenergic receptor; Arr, arrestin; DMI, desipramine; EPM, elevated plus maze; FLX, fluoxetine; FST, forced swim test; GPCR, G protein-coupled rece
Synthetic biology with surgical precision: Targeted reengineering of signaling proteins
Keywords: آرستین; Cell signaling; Signaling pathways; Arrestin; GPCR; Scaffold protein; Protein engineering; Cell survival; Cell death
Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptors
Keywords: آرستین; BiFC; bimolecular fluorescence complementation; BIBO3304; (R)-N2-(diphenylacetyl)-N-[(4-(aminocarbonylaminomethyl-)phenyl)methyl]-argininamide; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; FCS; fluorescence correlation spectroscopy
Adenosine receptor desensitization and trafficking
Keywords: آرستین; Adenosine receptor; Desensitization; Internalization; Arrestin; Kinase
Adrenocorticotropin hormone (ACTH) effects on MAPK phosphorylation in human fasciculata cells and in embryonic kidney 293 cells expressing human melanocortin 2 receptor (MC2R) and MC2R accessory protein (MRAP)β
Keywords: آرستین; DAPI; 4â²,6â²-diamino-2-phenylindole dihydrochloride; ACTH; adrenocorticotropin hormone; Rp-cAMPS; adenosine-3-5-cyclic monophosphorothioate, Rp isomer; BFA; brefeldin A; Epac; exchange protein directly activated by cAMP; ERK; extracellular regulated re
Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder
Keywords: آرستین; G protein-coupled receptor kinase; Arrestin; Schizophrenia; Schizoaffective disorder; Postmortem; Protein expression; RNAse protection assay; mRNA expression
Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health
Keywords: آرستین; arrestin; rod photoreceptor; photoresponse; recovery; protein expression; electroretinography; COX IV; subunit IV of the cytochrome C oxidase; ERG; electroretinography; GRK1; G protein-coupled receptor kinase 1 (rhodopsin kinase); IS; inner segment; NSF;
The functional cycle of visual arrestins in photoreceptor cells
Keywords: آرستین; Arrestin; Rhodopsin; Signal shutoff; Photoreceptors; Protein-protein interactions;
Spectral sensitivity of light-induced hatching and expression of genes mediating photoreception in eggs of the Asian tadpole shrimp Triops granarius
Keywords: آرستین; Arrestin; Asian tadpole shrimp; Branchiopoda; Opsin; Phototransduction cascade; Spectral sensitivity; Visual pigment
β-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist
Keywords: آرستین; Arrestin; Extracellular signal-regulated kinase; SH-SY5Y; IGF-I receptor; mu-Opioid receptor; TransactivationANOVA, analysis of variance; DAMGO, [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin; DMSO, dimethylsulfoxide; EGFR, epidermal growth factor receptor; ERK 1/
Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: Identification of a recycling motif
Keywords: آرستین; CRTH2; G protein-coupled receptor; Internalization; GRKs; PKC; Arrestin
A scanning peptide array approach uncovers association sites within the JNK/βarrestin signalling complex
Keywords: آرستین; MAPK; Map kinase; JNK; c-Jun N-terminal kinase; ASK1; apoptosis signal-regulating kinase 1; MKK4; MAPK kinase 4; CD site; common docking site; Arrestin; JNK; Scaffold; MKK4; ASK1; Peptide array;
G protein-coupled receptors stimulation and the control of cell migration
Keywords: آرستین; G protein-coupled receptors; Migration; Actin remodeling; G proteins; Arrestin
Ubiquitin ligase adaptors: Regulators of ubiquitylation and endocytosis of plasma membrane proteins
Keywords: آرستین; Ubiquitin; Substrate specificity; Ubiquitin ligase; Adaptor; Endocytosis; Nedd4; Rsp5; Cbl; Arrestin
β-arrestin2 regulates parathyroid hormone effects on a p38 MAPK and NFκB gene expression network in osteoblasts
Keywords: آرستین; PTH; Bone; Arrestin; Osteoblast; Gene expression
Functional characterization of kurtz, a Drosophila non-visual arrestin, reveals conservation of GPCR desensitization mechanisms
Keywords: آرستین; Arrestin; G protein-coupled receptor; Drosophila; Desensitization; Endocytosis
Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases
Keywords: آرستین; 5-HT2A; 5-Hydroxytryptamine; Serotonin; PSD95; Arrestin; Caveolin; Lipid raft; RSK2; PKC; GPCR; Gq; PDZ; Post-synaptic density; Desensitization; Trafficking; Endocytosis; Internalization; Scaffolding
The human angiotensin AT1 receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation
Keywords: آرستین; GPCR; 7TM receptor; Differential activation; Angiotensin; Arrestin; AT1 receptor
Desensitization of herpesvirus-encoded G protein-coupled receptors
Keywords: آرستین; GPCR; Cytomegalovirus; KSHV; HCMV; MCMV; US28; M33; ORF74; GRK; Arrestin; Desensitization
A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction
Keywords: آرستین; Arrestin; Desensitization; Olfaction; Anopheles gambiae; Drosophila melanogaster
Rod photoreceptor differentiation in fetal and infant human retina
Keywords: آرستین; rod opsin; cone opsin; arrestin; NRL; NR2E3; peripherin; recoverin; AIPL1