دانلود مقالات ISI درباره ATM، Ataxia telangiectasia جهش یافته است + ترجمه فارسی

پروتئین های تلومر در تومور زایی و نتایج بالینی کارسینوم سلول سنگفرشی دهان

The telomere proteins in tumorigenesis and clinical outcomes of oral squamous cell carcinoma

Keywords: ATM، Ataxia telangiectasia جهش یافته است; Head and neck cancer; Telomeres; Telomerase; Shelterin; Oral cancer; Oral squamous cell carcinoma; TumorigenesisAPC, antigen presenting cell; ALT, alternative lenghtening telomeres; ATM, ataxia telangiectasia mutated; AAH, atypical adenomatous hyperplasia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

فاکتور القاء شده با هیپوکسی - الفا: یک هدف درمانی انتزاعی در اندومتریوز است

Hypoxia-inducible factor-1alpha: A promising therapeutic target in endometriosis

Keywords: ATM، Ataxia telangiectasia جهش یافته است; Hypoxia-inducible factor-1alpha; Endometriosis; Etiology; Promising; Therapeutic targetANX, annexin; ANXA2, annexin A2; ARD, arrest defective; Asn, asparagine; ATM, ataxia telangiectasia mutated; bHLH-PAS, basic helix-loop-helix Per/Arnt/Sim; CBP, CREB bi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

اثر دوز کم دوز تابش یونیزه بر سلول های بنیادی بافت نرم

Low dose effects of ionizing radiation on normal tissue stem cells

Keywords: ATM، Ataxia telangiectasia جهش یافته است; Normal stem cells; Irradiation; Low dose; CarcinogenesisAPE1, Apurinic endonuclease; ATM, ataxia telangiectasia mutated; BER, base excision repair; CSC, cancer stem cell; DNA DSB, DNA double strand break; ESC, Embryonic stem cell; EMT, Epithelial-to-Mesen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

تعاملات بین هیدروکربن های آروماتیک چند حلقه ای در ترکیبات پیچیده و پیامدهای آن برای ارزیابی خطر سرطان

Interactions between polycyclic aromatic hydrocarbons in complex mixtures and implications for cancer risk assessment

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AhR, aryl hydrocarbon receptor; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad3-related protein; B[a]P, benzo[a]pyrene; B[a]Peq, B[a]P-equivalent; Chk1, checkpoint kinase 1; CT, coal tar; CYP, cytochrome P450; DE, diol epoxide; DNA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

تقویت هم افزایی از سمیت سلولی (-) - lomaiviticin توسط مهارکننده ATR VE-821

Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATR, ataxia telangiectasia and Rad3-related protein; SSB, single-strand break; DSB, double-strand break; PI3KK, phosphatidylinositol 3-kinase-related kinase; ATM, ataxia telangiectasia mutated; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; BRC

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Uridine homeostatic disorder leads to DNA damage and tumorigenesis

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; ATP, adenosine triphosphate; ATR, ATM-Rad3-related; BER, base excision repair; CTP, cytidine 5′-triphosphate; DAPI, 4′,6-diamidino-2-phenylindole; dCDP, deoxycytidine 5′-diphosphate; dCTP, deoxycytidine 5′-triphosphate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AD, Alzheimer's disease; AT, ataxia-telangiectasia; ATM, ataxia telangiectasia mutated; CP, core promoter; mcc, methylation correlation coefficient; MCI, mild cognitive impairment; mCpG, methyl-CpG; MID, multiplex identifiers; MMSE, minimental state exami

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ApG, adenine-guanine; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad3 related kinase; Bax, Bcl2-associated X protein; Bcl2, B-cell/lymphoma 2; Chk1, checkpoint kinase 1; Chk2, checkpoint kinase 2; CisPt, cisplatin; Ctr1, solute car

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease

Keywords: ATM، Ataxia telangiectasia جهش یافته است; PKC, Protein kinase C; PKCδ, Protein kinase C-δ; TPA, 12-O-tetradecanoylphorbol-13-acetate; DAG, Diaclyglyerol; RACK, Receptor for activated C-kinase; AKAP, A-kinase anchoring protein; ATM, Ataxia telangiectasia mutated; ERK, Extracellular regulated kinas

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; AP, apurinic/apyrimidinic; APE1, AP endonuclease 1; ATM, ataxia telangiectasia mutated; ATR, ATM Rad3-related protein; BER, base excision repair; DNA-PKcs, DNA-dependent protein kinases; ERCC1, excision repair cross-co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Phospho-ΔNp63α-responsive microRNAs contribute to the regulation of necroptosis in squamous cell carcinoma upon cisplatin exposure

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATG, autophagy-related protein; ATM, ataxia telangiectasia mutated; BCL, B-cell lymphoma; CIS, cisplatin; CYLD, cylindromatosis; DAP3, death-assocated protein; DAPK, death-associated protein kinase; IAP, inhibitor of apoptosis; IP, immunoprecipitation; ML

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

In silico analysis of consequences of non-synonymous SNPs of Slc11a2 gene in Indian bovines

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; BRAF, B-Raf; CFTR, cystic fibrosis transmembrane conductance regulator; GalNAc-T1, N-acetylgalactosaminyltransferase 1; GATK, Genome Analysis Tool Kit; HBB, hemoglobin beta; HMM, Hidden Markov Model; IGF1R, insulin-like

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

MKP1 phosphatase mediates G1-specific dephosphorylation of H3Serine10P in response to DNA damage

Keywords: ATM، Ataxia telangiectasia جهش یافته است; DDR, DNA damage response; MSK1, Mitogen and stress-activated protein kinase-1; MKP1, Mitogen-activated protein kinase phosphatase-1; ATM, Ataxia telangiectasia mutated; VEGF, Vascular endothelial growth factor; S10P, serine10 phosphorylation; IR, ionizati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad3-related; BER, base excision repair; DSB, double-strand break; H3K4me2, histone H3 lysine 4 dimethylation; H3K4me3, histone H3 lysine 4 trimethylation; H3K9me2, histone H3 lysine 9 dim

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Selective killing of G2 decatenation checkpoint defective colon cancer cells by catalytic topoisomerase II inhibitor

Keywords: ATM، Ataxia telangiectasia جهش یافته است; Topo IIα, topoisomerase IIα; ATM, ataxia telangiectasia mutated; Chk2, checkpoint kinase 2G2 DNA decatenation checkpoint; Topoisomerase IIα; Colorectal cancer; ICRF193; Mitotic catastrophe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A novel assay revealed that ribonucleotide reductase is functionally important for interstrand DNA crosslink repair

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, Ataxia telangiectasia mutated; ATR, ATM and rad3-related; BCA, bicinchoninic acid; Chk1, checkpoint kinase 1; DDR, DNA damage response/repair; DMSO, dimethyl sulfoxide; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum; HEPES, 2-[4-(2-hy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; DAPI, 4′,6-diamidino-2-phenylindole; DDR, DNA damage response; DSB, double strand break; EMA, ethydium monoazide; ETO, etoposide; γH2AX, phosphorylated histone H2AX serine 139/140; IVMN, in vitro micronucleus; NOS, nosc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Bmi-1: At the crossroads of physiological and pathological biology

Keywords: ATM، Ataxia telangiectasia جهش یافته است; Aging; Bmi-1; Cancer; Post translational modification; Stem cellASC, adult stem cell; ATM, Ataxia telangiectasia mutated; BASC, bronchioalveolar stem cell; Bmi-1, B-cell specific Moloney murine virus integration site 1; CIC, cancer initiating cell; CSC, c

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Functional characterization of genetic polymorphisms in the H2AFX distal promoter

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; DNA-PK, DNA dependent protein kinase; γ-H2AX, phosphorylated H2AX; SNP, single nucleotide polymorphism; NHL, non Hodgkin lymphoma; DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; MCL, mantle cell lymphoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

γ-H2AX as a biomarker for DNA double-strand breaks in ecotoxicology

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 5-FU, 5-fluorouracil; 53BP1, p53 binding protein 1; API, aphidicolin; ARA-C, cytarabine; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia related; BLAP, ß-lapachone; BLM, bleomycin; BRCA1, breast cancer type 1 susceptibility protein; cDDP, c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Repair of endogenous DNA base lesions modulate lifespan in mice

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 3meA, 3-methyladenine; Aag/Mpg, alkyladenine glycosylase; AP, abasic; Atm, ataxia telangiectasia mutated; BER, base excision repair; BM, bone marrow; CR, calorie restriction; Exo1, exonuclease 1; Mgmt, O6MeG DNA methyltransferase; MMR, mismatch repair; MM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, Ataxia telangiectasia mutated; ATR, Ataxia telangiectasia-Rad3-related; BER, Base excision repair; CEES, 2-chloroethyl ethyl sulfide; DAPI, 4′,6′-diamidino-2-phenylindole; DMSO, Dimethyl sulfoxide; DSB, Double strand breaks; FACS, Fluorescence activa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Interaction between Rad9–Hus1–Rad1 and TopBP1 activates ATR–ATRIP and promotes TopBP1 recruitment to sites of UV-damage

Keywords: ATM، Ataxia telangiectasia جهش یافته است; Rad, radiation sensitive; Hus, hydroxyurea sensitive; 9–1–1, Rad9–Hus1–Rad1; ser, serine; TopBP1, DNA Topoisomerase II Binding Protein 1; CK2, casein kinase 2; ATR, ATM- and Rad3-related; Chk1, checkpoint kinase 1; ATM, Ataxia telangiectasia mutated; ATRI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AOH, alternariol; AO, acridine orange; AMPK, AMP-activated protein kinase; ATM, ataxia telangiectasia mutated; SA-β-Gal, senescence-associate-β-galactosidase; BSA, bovine serum albumin; ConA, concanamycin A; CQ, chloroquine; DMEM, Dulbecco’s modified eagl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Sensitivity to methylmercury toxicity is enhanced in oxoguanine glycosylase 1 knockout murine embryonic fibroblasts and is dependent on cellular proliferation capacity

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 8-oxodG, 8-oxo-2′-deoxyguanosine; ATM, ataxia telangiectasia mutated; ATR, AT and Rad3-related protein; BER, base excision repair; BrdU, bromodeoxyuridine; BSA, bovine serum albumin; CBP, CREB1-binding protein; DAPI, 4′-6-Diamidino-2-phenylindole; DNA-PK,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of glutathione synthesis in brain endothelial cells lengthens S-phase transit time in the cell cycle: Implications for proliferation in recovery from oxidative stress and endothelial cell damage

Keywords: ATM، Ataxia telangiectasia جهش یافته است; GSH, glutathione; GSSG, glutathione disulfide; H1, histone H1; cdk1, cyclin dependent kinase 1; ATM, ataxia telangiectasia mutated; chk2, checkpoint kinase 2; GAPDH, glyceraldehyde 3-phosphate dehydrogenaseNuclear-to-cytosolic GSH distribution; GSH and en

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Functional analysis—Make or break for cancer predictability

Keywords: ATM، Ataxia telangiectasia جهش یافته است; array-CGH, array comparative genomic hybridization; ATM, Ataxia telangiectasia mutated; BACH1, BRCA1 associated C-terminal helicase 1; BRCA1, breast-cancer susceptibility gene 1; BRCA2, breast-cancer susceptibility gene 2; CHEK2, gene encoding checkpoint

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AOH, alternariol; AME, alternariol monomethyl ether; ATM, ataxia telangiectasia mutated; 12-DSA, 12-Doxyl Stearic Acid; ATR, ATM-Rad3-related; BSA, bovine serum albumin; Chk-1/2, checkpoint kinase 1/2; DMEM, Dulbecco's Modified Eagle Medium; DSBs, DNA dou

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The interferon response to intracellular DNA: Why so many receptors?

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AIM2, absent in melanoma 2; ASC, apoptosis-associated speck-like protein containing a CARD; ATLD, ataxia-telangiectasia-like disorder cells; ATM, Ataxia telangiectasia mutated; BMDC, bone marrow-derived dendritic cells; BMDM, bone marrow-derived macrophag

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of RSF-1, the Caenorhabditis elegans homolog of the Ras-association domain family protein 1

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; C. elegans, Caenorhabditis elegans; C1, conserved phorbol ester/diacylglycerol-binding; Gex, gut on the exterior; GFP, green fluorescent protein; GST, glutathione S-transferase; MST, mammalian Ste20-like kinases; MuV, m

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

DNA-damage response in chromatin of ribosomal genes and the surrounding genome

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 53BP1, p53-binding protein; AOTF, acousto-optic tunable filter; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad-related kinase; BrdU, 5-bromo-2′-deoxy-uridine; CD, chromodomain; ChIP–PCR, chromatin immunoprecipitation–polymerase cha

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Ligand modulation of a dinuclear platinum compound leads to mechanistic differences in cell cycle progression and arrest

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, Ataxia Telangiectasia Mutated; ATR, Ataxia Telangiectasia Mutated and Rad3 related; BrdU, bromodeoxyuridine; CDK, cyclin dependent kinase; Chk1, checkpoint kinase 1; DACH, 1,2-diaminocyclohexane; Gy, Gray; MTT, (3,4,5-dimethylthiazol-2-yl)-2,5-diphen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; CMFDA, 5-chloromethylfluorescein diacetate; DAPI, 4′,6-diamidino-2-phenylindole; DR4/5, death receptor 4/5; Fas, fatty acid synthase; FADD, Fas-associated protein with death domain; FITC, fluorescein isothiocyanate; GSH

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

The role of BRCA1 in DNA double-strand repair: Past and present

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 53BP1, p53 binding protein 1; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia mutated rad3-related; ATRIP, ATR-interacting protein; BACH1, BRCA1-associated C-terminal helicase; BARD1, BRCA1-associated RING domain; BASC, BRCA1-associated gen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells

Keywords: ATM، Ataxia telangiectasia جهش یافته است; DSBs, double-strand breaks; NHEJ, non-homologous end joining; HR, homologous recombination; ENU, N-ethyl-N-nitrosourea; RIC, radiation induced curly tailed; DNA-PKcs, DNA dependent protein kinase catalytic subunit; ATM, ataxia telangiectasia mutated; ATR,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Saccharomyces cerevisiae Tel2 plays roles in TORC signaling and telomere maintenance that can be mutationally separated

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ASTRA, assembly of Tel, Rvb and Atm-like kinases; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3 related; FOA, 5-fluoroorotic acid; HU, hydroxyurea; MMS, methyl methanesulfonate; PIKK, phosphatidylinositol 3-kinase-like protein kinase; TORC, target

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Signaling pathways in aged T cells – A reflection of T cell differentiation, cell senescence and host environment

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AKT, protein kinase B; AMPK, AMP-activated protein kinase; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia-related; DNA-PKcs, catalytic subunit of DNA-dependent protein kinase; DSB, double strand break; DUSP, dual-specific phosphatase; HAAR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Autocrine regulation of γ-irradiation-induced DNA damage response via extracellular nucleotides-mediated activation of P2Y6 and P2Y12 receptors

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; γH2AX, phosphorylated histone variant H2AX; shRNA, short hairpin RNA plasmid; 53BP1, tumor suppressor p53-binding protein 1DNA damage response; Radiation; Purinergic receptor; ATP; γH2AX; ATM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

Keywords: ATM، Ataxia telangiectasia جهش یافته است; AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK, AMP-activated kinase; ATM, ataxia telangiectasia mutated; CHK2, checkpoint kinase 2; COPD, chronic obstructive pulmonary disease; DDR, DNA damage response; DSB, double-strand break; EGCG, e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Impacts of low doses of pesticide mixtures on liver cell defence systems

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ADI, acceptable daily intake; ATM, ataxia telangiectasia mutated; BCL2, B cell lymphoma 2; BRCA1/2, breast cancer 1 and 2, early onset proteins; CHEK2, checkpoint kinase 2; GST, glutahione S-transferase; CYP, cytochrome P450; H2AX, histone H2A-member X; T

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 8-oxodG, 8-oxo-7,8-dihydro-2′-deoxyguanosine; AFU, Arbitrary fluorescence units; ATM, Ataxia telangiectasia mutated; BRCA1/2, Breast cancer gene 1/2; Cp, Crossing point; DF4, DharmaFECT-4; DME, Dulbecco's modified Eagle's medium; ERCC1 to 8, Excision repa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Reversion of the ErbB malignant phenotype and the DNA damage response

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ARG, amphiregulin; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; BRCA1/2, breast cancer type 1/2 susceptibility protein; DNA-PK, DNA dependent protein kinase; DSB, double strand break; EGF, epidermal growth factor; EGFR, epidermal growth

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA–PKcs and PARP-1

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; DNA–PKcs, DNA-dependent protein kinase catalytic subunit; PARP-1, poly(ADP-ribose) polymerase; PAR, anti-poly(ADP-ribose); 3-MA, 3-methyladenine; 3-AB, 3-aminobenzamide; AMPKα, AMP-activated protein kinase-α; LC3, micro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ALL, acute lymphocytic leukemia; APAF-1, apoptotic protease-activating factor 1; AIF, apoptosis-inducing factor; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad3-related; CBP, cAMP-response element-binding protein-binding protein; C

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Family friction as ΔNp73 antagonises p73 and p53

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, Ataxia Telangiectasia Mutated; MEF, mouse embryonic fibroblast; Mdm2, double minute protein; PTEN, phosphatase and tensin homolog; p53AIP1, p53 apoptosis inducing protein 1; PIR2, p73 induced RING 2 protein; SAOS, sarcoma osteogenic; WT, wild type; 5

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Valproic acid-induced DNA damage increases embryonic p27KIP1 and caspase-3 expression: A mechanism for valproic-acid induced neural tube defects

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; ATR, ATM and RAD3-related; BSA, bovine serum albumin; DAB, 3,3-diaminobenzidine; DNAPKcs, DNA-protein kinase catalytic subunit; DSB, double strand break; GD, gestational day; NTD, neural tube defect; γH2AX, phosphorylat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

DNA damage response: The emerging role of c-Abl as a regulatory switch?

Keywords: ATM، Ataxia telangiectasia جهش یافته است; 53BP1, Tumor suppressor p53-binding protein 1; ATM, Ataxia telangiectasia mutated; ATR, Ataxia telangiectasia and Rad3-related protein; BARD, BRCA1-associated RING domain protein 1; BER, Base excision repair; BRCA1, Breast cancer type 1 susceptibility pro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Role of DNA damage in atherosclerosis—Bystander or participant?

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ApoE−/−, Apolipoprotein E deficient; ATM, Ataxia Telangiectasia Mutated; ATR, ATM- and Rad3-related protein; BER, base-excision repair; CHK1/2, checkpoint kinase 1 or checkpoint kinase 2; CtIP, C-terminal interacting protein; DDR, DNA damage response path

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mode of ATM-dependent suppression of chromosome translocation

Keywords: ATM، Ataxia telangiectasia جهش یافته است; ATM, ataxia telangiectasia mutated; DNA-PK, DNA-dependent protein kinase; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; DSB, DNA double-strand break; IR, ionizing radiation; NHEJ, non-homologous end-joining; MMEJ, microhomology-mediated end-jo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog

Keywords: ATM، Ataxia telangiectasia جهش یافته است; DAP, 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV); Cdk, cyclin-dependent kinase; IC50, inhibitory concentration reducing tumor cell growth by 50%; HMGB, high mobility group box; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiect

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه