
Transdermal delivery of relatively high molecular weight drugs using novel self-dissolving microneedle arrays fabricated from hyaluronic acid and their characteristics and safety after application to the skin
Keywords: HA; hyaluronic acid; FD4; fluorescein isothiocyanate-labeled dextran with an average molecular weight of 4Â kDa; TEWL; transepidermal water loss; TER; transcutaneous electrical resistance; H&E; hematoxylin and eosin; P.I.I.; Primary Irritation Index; Micr